Biomarkers of endothelial cell activation: Candidate markers for drug-induced vasculitis in patients or drug-induced vascular injury in animals

Vascular Pharmacology

Volumn 56, Issue 1-2, 2012, Pages 14-25

  Zhang, Jun ^a   Hanig, Joseph P ^a   De Felice, Albert F ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

ANCA associated small vessel vasculitis; Drug induced vasculitis; Endothelial biomarkers; Endothelial cell activation

Indexed keywords

ANTICOAGULANT AGENT; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CELL ADHESION MOLECULE; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FENOLDOPAM; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HAPTOGLOBIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MINOCYCLINE; N (3,5 DICHLORO 1 OXIDO 4 PYRIDINYL) 8 METHOXY 2 TRIFLUOROMETHYL 5 QUINOLINECARBOXAMIDE; NERVE GROWTH FACTOR; NEUTROPHIL CYTOPLASMIC ANTIBODY; OROSOMUCOID; PADGEM PROTEIN; PHOSPHODIESTERASE V INHIBITOR; REACTIVE OXYGEN METABOLITE; SCATTER FACTOR; SCH 534385; THROMBIN; THROMBOMODULIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN; VON WILLEBRAND FACTOR;

ANCA ASSOCIATED SMALL VESSEL VASCULITIS; ARTERIOLE; ARTERY; BLOOD VESSEL; BLOOD VESSEL INJURY; CAPILLARY; CELL ACTIVATION; CELL PROLIFERATION; CHURG STRAUSS SYNDROME; CIRCULATING ENDOTHELIAL CELL; CIRCULATION; CYTOKINE PRODUCTION; DRUG INDUCED VASCULAR INJURY; DRUG SAFETY; ENDOTHELIUM CELL; GLOMERULONEPHRITIS; HISTOPATHOLOGY; HUMAN; IMMUNOPATHOGENESIS; IN VITRO STUDY; IN VIVO STUDY; INJURY SEVERITY; LEUKOCYTE ACTIVATION; MACROPHAGE; MAST CELL; MICROSCOPIC POLYANGIITIS; MUCOCUTANEOUS LYMPH NODE SYNDROME; NECROTIZING ARTERITIS; NECROTIZING CRESCENTIC GLOMERULONEPHRITIS; NEUTROPHIL; NONHUMAN; PHENOTYPE; POLYARTERITIS NODOSA; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SECRETION; REVIEW; SYSTEMIC VASCULITIS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; VASCULAR ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM; VASCULAR NECROSIS; VASCULITIS; VENULE; WEGENER GRANULOMATOSIS;

ANIMALS; BIOLOGICAL MARKERS; ENDOTHELIAL CELLS; HUMANS; VASCULAR SYSTEM INJURIES; VASCULITIS;

EID: 84856266010     PISSN: 15371891     EISSN: 18793649     Source Type: Journal    
DOI: 10.1016/j.vph.2011.09.002     Document Type: Review

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