Lethality in a murine model of pulmonary anthrax is reduced by combining nuclear transport modifier with antimicrobial therapy

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Veach, Ruth Ann ^a   Zienkiewicz, Jozef ^a   Collins, Robert D ^a   Hawiger, Jacek ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; ERYTHROPOIETIN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; SN 50; TUMOR NECROSIS FACTOR ALPHA; ANTIINFECTIVE AGENT; CELL PENETRATING PEPTIDE; CSN50 PEPTIDE; CYCLOPEPTIDE; CYTOKINE; MEMBRANE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTHRAX; ARTICLE; BACILLUS ANTHRACIS; BACTERIAL COUNT; BLOOD VESSEL INJURY; CLINICAL PROTOCOL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE MODEL; FEMALE; HISTOPATHOLOGY; HOST RESISTANCE; INNATE IMMUNITY; LETHALITY; LUNG PARENCHYMA; MORTALITY; MOUSE; NONHUMAN; SINGLE DRUG DOSE; SURVIVAL RATE; TREATMENT DURATION; TREATMENT OUTCOME; ACTIVE TRANSPORT; ANIMAL; BLOOD; DRUG COMBINATION; DRUG EFFECT; EVALUATION; LUNG DISEASE; METABOLISM; PATHOLOGY; SURVIVAL;

ANIMALIA; BACILLUS ANTHRACIS; MURINAE; MUS;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTHRAX; ANTI-INFECTIVE AGENTS; CELL-PENETRATING PEPTIDES; CIPROFLOXACIN; CYTOKINES; DISEASE MODELS, ANIMAL; DRUG COMBINATIONS; FEMALE; LUNG DISEASES; MEMBRANE PROTEINS; MICE; PEPTIDES, CYCLIC; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84856259565     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030527     Document Type: Article

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