Bacillus anthracis lethal toxin disrupts TCR signaling in CD1d-restricted NKT cells leading to functional anergy

PLoS Pathogens

Volumn 5, Issue 9, 2009, Pages

  Joshi, Sunil K ^a   Lang, Gillian A ^a   Larabee, Jason L ^a   Devera, T Scott ^a   Aye, Lindsay M ^a   Shah, Hemangi B ^a   Ballard, Jimmy D ^a   Lang, Mark L ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX TOXIN; BACTERIAL TOXIN; CD1D ANTIGEN; CMG 2 TOXIN; CYTOKINE; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; NATURAL KILLER CELL RECEPTOR NKG2D; T LYMPHOCYTE RECEPTOR; TEM 8 TOXIN; UNCLASSIFIED DRUG; ALPHA GALACTOSYLCERAMIDE; ALPHA-GALACTOSYLCERAMIDE; ANTHRAX TOXIN RECEPTORS; BACTERIAL ANTIGEN; GALACTOSYLCERAMIDE; LYMPHOCYTE ANTIGEN RECEPTOR; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K; RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTHRAX; ARTICLE; BACILLUS ANTHRACIS; C57BL 6 MOUSE; CELL TYPE; CLONAL ANERGY; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; HOST; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; LETHAL GENE; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; DRUG EFFECT; FLOW CYTOMETRY; IMMUNOLOGY; METABOLISM; SIGNAL TRANSDUCTION;

BACILLUS ANTHRACIS; MUS;

ANIMALS; ANTIGENS, BACTERIAL; ANTIGENS, CD1D; BACILLUS ANTHRACIS; BACTERIAL TOXINS; CYTOKINES; FEMALE; FLOW CYTOMETRY; GALACTOSYLCERAMIDES; MICE; MICE, INBRED C57BL; NATURAL KILLER T-CELLS; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, PEPTIDE; SIGNAL TRANSDUCTION;

EID: 70349677168     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000588     Document Type: Article

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