Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in mice

Hypertension

Volumn 59, Issue 2, 2012, Pages 348-354

  Jennings, Brett L ^a   Anderson, Larry J ^a   Estes, Anne M ^a   Yaghini, Fariborz A ^a   Fang, Xiao R ^a   Porter, Jason ^a   Gonzalez, Frank J ^b   Campbell, William B ^c   Malik, Kafait U ^a  

^a UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Angiotensin II; CYP1B1; Cyp1b1 mice; Oxidative stress; Renal function

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; 20 HYDROXYICOSATETRAENOIC ACID; ANGIOTENSIN II; CYTOCHROME P450 1B1; MITOGEN ACTIVATED PROTEIN KINASE; POTASSIUM; PROTEIN KINASE P60; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SODIUM;

ALBUMINURIA; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG TARGETING; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; FLUID INTAKE; GENE DISRUPTION; GENE EXPRESSION; HYPERTENSION; INFLAMMATION; KIDNEY DYSFUNCTION; KIDNEY FIBROSIS; KIDNEY INJURY; KIDNEY TUBULE; KIDNEY TUBULE DAMAGE; MALE; MOUSE; NONHUMAN; OSMOTIC MINIPUMP; POTASSIUM URINE LEVEL; PRIORITY JOURNAL; PROTEINURIA; SODIUM URINE LEVEL; SYSTOLIC BLOOD PRESSURE; THIRST; URINE OSMOLALITY; URINE VOLUME; VASCULAR RESISTANCE;

ANGIOTENSIN II; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROSIS; HYPERTENSION; KIDNEY; MALE; MICE; MICE, KNOCKOUT; NADPH OXIDASE; PROTEIN-TYROSINE KINASES; REACTIVE OXYGEN SPECIES; SODIUM; VASCULAR RESISTANCE;

EID: 84856237440     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.183301     Document Type: Article

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