메뉴 건너뛰기




Volumn 125, Issue 1, 2010, Pages 27-38

A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link?

Author keywords

Angiotensin II type 1 receptor; Blood pressure; Hypertension; Signaling; Sympathetic; Tissue localized renin angiotensin system

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; ANGIOTENSINOGEN; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PRORENIN RECEPTOR; RENIN; RENIN INHIBITOR;

EID: 72149091180     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2009.07.007     Document Type: Review
Times cited : (78)

References (186)
  • 1
    • 0000761147 scopus 로고    scopus 로고
    • Blockade of angiotensin AT1-receptors in the rostral ventrolateral medulla of spontaneously hypertensive rats reduces blood pressure and sympathetic nerve discharge
    • Allen A.M. Blockade of angiotensin AT1-receptors in the rostral ventrolateral medulla of spontaneously hypertensive rats reduces blood pressure and sympathetic nerve discharge. J Renin Angiotensin Aldosterone Syst 2 (2001) s120-s124
    • (2001) J Renin Angiotensin Aldosterone Syst , vol.2
    • Allen, A.M.1
  • 2
    • 33744982448 scopus 로고    scopus 로고
    • Expression of constitutively active angiotensin receptors in the rostral ventrolateral medulla increases blood pressure
    • Allen A.M., Dosanjh J.K., Erac M., Dassanayake S., Hannan R.D., and Thomas W.G. Expression of constitutively active angiotensin receptors in the rostral ventrolateral medulla increases blood pressure. Hypertension 47 (2006) 1054-1061
    • (2006) Hypertension , vol.47 , pp. 1054-1061
    • Allen, A.M.1    Dosanjh, J.K.2    Erac, M.3    Dassanayake, S.4    Hannan, R.D.5    Thomas, W.G.6
  • 4
    • 0029032759 scopus 로고
    • Developmental analysis of murine Promyelocyte Leukemia Zinc Finger (PLZF) gene expression: implications for the neuromeric model of the forebrain organization
    • Avantaggiato V., Pandolfi P.P., Ruthardt M., Hawe N., Acampora D., Pelicci P.G., et al. Developmental analysis of murine Promyelocyte Leukemia Zinc Finger (PLZF) gene expression: implications for the neuromeric model of the forebrain organization. J Neurosci 15 (1995) 4927-4942
    • (1995) J Neurosci , vol.15 , pp. 4927-4942
    • Avantaggiato, V.1    Pandolfi, P.P.2    Ruthardt, M.3    Hawe, N.4    Acampora, D.5    Pelicci, P.G.6
  • 5
    • 0033956392 scopus 로고    scopus 로고
    • Angiotensin peptides and baroreflex control of sympathetic outflow: pathways and mechanisms of the medulla oblongata
    • Averill D.B., and Diz D.I. Angiotensin peptides and baroreflex control of sympathetic outflow: pathways and mechanisms of the medulla oblongata. Brain Res Bull 51 (2000) 119-128
    • (2000) Brain Res Bull , vol.51 , pp. 119-128
    • Averill, D.B.1    Diz, D.I.2
  • 6
    • 0037059508 scopus 로고    scopus 로고
    • It's renin in the brain: transgenic animals elucidate the brain renin-angiotensin system
    • Bader M., and Ganten D. It's renin in the brain: transgenic animals elucidate the brain renin-angiotensin system. Circ Res 90 (2002) 8-10
    • (2002) Circ Res , vol.90 , pp. 8-10
    • Bader, M.1    Ganten, D.2
  • 7
    • 0035074165 scopus 로고    scopus 로고
    • Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research
    • Bader M., Peters J., Baltatu O., Muller D.N., Luft F.C., and Ganten D. Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research. J Mol Med 79 (2001) 76-102
    • (2001) J Mol Med , vol.79 , pp. 76-102
    • Bader, M.1    Peters, J.2    Baltatu, O.3    Muller, D.N.4    Luft, F.C.5    Ganten, D.6
  • 8
    • 0031011283 scopus 로고    scopus 로고
    • Role of vasopressin in essential hypertension: racial differences
    • Bakris G., Bursztyn M., Gavras I., Bresnahan M., and Gavras H. Role of vasopressin in essential hypertension: racial differences. J Hypertens 15 (1997) 545-550
    • (1997) J Hypertens , vol.15 , pp. 545-550
    • Bakris, G.1    Bursztyn, M.2    Gavras, I.3    Bresnahan, M.4    Gavras, H.5
  • 9
    • 27744496889 scopus 로고    scopus 로고
    • Vasopressin-V2 receptor stimulation reduces sodium excretion in healthy humans
    • Bankir L., Fernandes S., Bardoux P., Bouby N., and Bichet D.G. Vasopressin-V2 receptor stimulation reduces sodium excretion in healthy humans. J Am Soc Nephrol 16 (2005) 1920-1928
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1920-1928
    • Bankir, L.1    Fernandes, S.2    Bardoux, P.3    Bouby, N.4    Bichet, D.G.5
  • 10
    • 34548843043 scopus 로고    scopus 로고
    • Ethnic differences in urine concentration: possible relationship to blood pressure
    • Bankir L., Perucca J., and Weinberger M.H. Ethnic differences in urine concentration: possible relationship to blood pressure. Clin J Am Soc Nephrol 2 (2007) 304-312
    • (2007) Clin J Am Soc Nephrol , vol.2 , pp. 304-312
    • Bankir, L.1    Perucca, J.2    Weinberger, M.H.3
  • 11
    • 0037405846 scopus 로고    scopus 로고
    • Angiotensin potentiates excitatory sensory synaptic transmission to medial solitary tract nucleus neurons
    • Barnes K.L., DeWeese D.M., and Andresen M.C. Angiotensin potentiates excitatory sensory synaptic transmission to medial solitary tract nucleus neurons. Am J Physiol Regul Integr Comp Physiol 284 (2003) R1340-1353
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.284
    • Barnes, K.L.1    DeWeese, D.M.2    Andresen, M.C.3
  • 12
    • 56749131247 scopus 로고    scopus 로고
    • Prorenin and the (pro)renin receptor: binding kinetics, signalling and interaction with aliskiren
    • Batenburg W.W., and Danser A.J. Prorenin and the (pro)renin receptor: binding kinetics, signalling and interaction with aliskiren. J Renin Angiotensin Aldosterone Syst 9 (2008) 181-184
    • (2008) J Renin Angiotensin Aldosterone Syst , vol.9 , pp. 181-184
    • Batenburg, W.W.1    Danser, A.J.2
  • 13
    • 43049090108 scopus 로고    scopus 로고
    • The (pro)renin receptor: a new addition to the renin-angiotensin system?
    • Batenburg W.W., and Jan Danser A.H. The (pro)renin receptor: a new addition to the renin-angiotensin system?. Eur J Pharmacol 585 (2008) 320-324
    • (2008) Eur J Pharmacol , vol.585 , pp. 320-324
    • Batenburg, W.W.1    Jan Danser, A.H.2
  • 14
    • 35848948398 scopus 로고    scopus 로고
    • Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor
    • Batenburg W.W., Krop M., Garrelds I.M., de Vries R., de Bruin R.J., Burckle C.A., et al. Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor. J Hypertens 25 (2007) 2441-2453
    • (2007) J Hypertens , vol.25 , pp. 2441-2453
    • Batenburg, W.W.1    Krop, M.2    Garrelds, I.M.3    de Vries, R.4    de Bruin, R.J.5    Burckle, C.A.6
  • 16
    • 23844446135 scopus 로고    scopus 로고
    • Paraventricular nucleus, stress response, and cardiovascular disease
    • Benarroch E.E. Paraventricular nucleus, stress response, and cardiovascular disease. Clin Auton Res 15 (2005) 254-263
    • (2005) Clin Auton Res , vol.15 , pp. 254-263
    • Benarroch, E.E.1
  • 17
    • 0024453294 scopus 로고
    • Inositol phosphates and cell signalling
    • Berridge M.J., and Irvine R.F. Inositol phosphates and cell signalling. Nature 341 (1989) 197-204
    • (1989) Nature , vol.341 , pp. 197-204
    • Berridge, M.J.1    Irvine, R.F.2
  • 18
    • 84964126120 scopus 로고
    • Evidence for a central mechanism in angiotensin induced hypertension
    • Bickerton R.K., and Buckley J.P. Evidence for a central mechanism in angiotensin induced hypertension. Proc Soc Exp Biol Med 106 (1961) 834-837
    • (1961) Proc Soc Exp Biol Med , vol.106 , pp. 834-837
    • Bickerton, R.K.1    Buckley, J.P.2
  • 20
    • 0035961206 scopus 로고    scopus 로고
    • Baroreflex inhibition of cardiac sympathetic outflow is attenuated by angiotensin II in the nucleus of the solitary tract
    • Boscan P., Allen A.M., and Paton J.F. Baroreflex inhibition of cardiac sympathetic outflow is attenuated by angiotensin II in the nucleus of the solitary tract. Neuroscience 103 (2001) 153-160
    • (2001) Neuroscience , vol.103 , pp. 153-160
    • Boscan, P.1    Allen, A.M.2    Paton, J.F.3
  • 21
    • 0021265041 scopus 로고
    • Activity patterns and osmosensitivity of rat supraoptic neurones in perfused hypothalamic explants
    • Bourque C.W., and Renaud L.P. Activity patterns and osmosensitivity of rat supraoptic neurones in perfused hypothalamic explants. J Physiol 349 (1984) 631-642
    • (1984) J Physiol , vol.349 , pp. 631-642
    • Bourque, C.W.1    Renaud, L.P.2
  • 22
    • 57449105452 scopus 로고    scopus 로고
    • Response of substances co-expressed in hypothalamic magnocellular neurons to osmotic challenges in normal and Brattleboro rats
    • Bundzikova J., Pirnik Z., Zelena D., Mikkelsen J.D., and Kiss A. Response of substances co-expressed in hypothalamic magnocellular neurons to osmotic challenges in normal and Brattleboro rats. Cell Mol Neurobiol 28 (2008) 1033-1047
    • (2008) Cell Mol Neurobiol , vol.28 , pp. 1033-1047
    • Bundzikova, J.1    Pirnik, Z.2    Zelena, D.3    Mikkelsen, J.D.4    Kiss, A.5
  • 23
    • 33750592956 scopus 로고    scopus 로고
    • Prorenin and its ancient receptor
    • Burckle C., and Bader M. Prorenin and its ancient receptor. Hypertension 48 (2006) 549-551
    • (2006) Hypertension , vol.48 , pp. 549-551
    • Burckle, C.1    Bader, M.2
  • 25
    • 0025138666 scopus 로고
    • Pressor hormones in elderly hypertensive persons. Racial differences
    • Bursztyn M., Bresnahan M., Gavras I., and Gavras H. Pressor hormones in elderly hypertensive persons. Racial differences. Hypertension 15 (1990) I88-92
    • (1990) Hypertension , vol.15
    • Bursztyn, M.1    Bresnahan, M.2    Gavras, I.3    Gavras, H.4
  • 27
    • 42349091494 scopus 로고    scopus 로고
    • Critical review of prorenin and (pro)renin receptor research
    • Campbell D.J. Critical review of prorenin and (pro)renin receptor research. Hypertension 51 (2008) 1259-1264
    • (2008) Hypertension , vol.51 , pp. 1259-1264
    • Campbell, D.J.1
  • 28
    • 0026409556 scopus 로고
    • Differential regulation of angiotensin peptide levels in plasma and kidney of the rat
    • Campbell D.J., Lawrence A.C., Towrie A., Kladis A., and Valentijn A.J. Differential regulation of angiotensin peptide levels in plasma and kidney of the rat. Hypertension 18 (1991) 763-773
    • (1991) Hypertension , vol.18 , pp. 763-773
    • Campbell, D.J.1    Lawrence, A.C.2    Towrie, A.3    Kladis, A.4    Valentijn, A.J.5
  • 29
    • 26844522807 scopus 로고    scopus 로고
    • NADPH oxidase-derived superoxide anion mediates angiotensin II-induced pressor effect via activation of p38 mitogen-activated protein kinase in the rostral ventrolateral medulla
    • Chan S.H., Hsu K.S., Huang C.C., Wang L.L., Ou C.C., and Chan J.Y. NADPH oxidase-derived superoxide anion mediates angiotensin II-induced pressor effect via activation of p38 mitogen-activated protein kinase in the rostral ventrolateral medulla. Circ Res 97 (2005) 772-780
    • (2005) Circ Res , vol.97 , pp. 772-780
    • Chan, S.H.1    Hsu, K.S.2    Huang, C.C.3    Wang, L.L.4    Ou, C.C.5    Chan, J.Y.6
  • 30
    • 34147190091 scopus 로고    scopus 로고
    • The baroreceptor reflex: novel methods and mechanisms
    • Dun N.J., Benedito H., and Pilowsky P.M. (Eds), Kluwer Academic Publishers, Norwell, MA
    • Chapleau M.W., and Abboud F.M. The baroreceptor reflex: novel methods and mechanisms. In: Dun N.J., Benedito H., and Pilowsky P.M. (Eds). Neural Mechanisms of Cardiovascular Regulation 1-29 (2004), Kluwer Academic Publishers, Norwell, MA
    • (2004) Neural Mechanisms of Cardiovascular Regulation , vol.1-29
    • Chapleau, M.W.1    Abboud, F.M.2
  • 31
    • 0029855362 scopus 로고    scopus 로고
    • The renin-angiotensin system and the heart: a historical review
    • Cleland S.J., and Reid J.L. The renin-angiotensin system and the heart: a historical review. Heart 76 (1996) 7-12
    • (1996) Heart , vol.76 , pp. 7-12
    • Cleland, S.J.1    Reid, J.L.2
  • 33
    • 0028258843 scopus 로고
    • Functional organization of central pathways regulating the cardiovascular system
    • Dampney R.A. Functional organization of central pathways regulating the cardiovascular system. Physiol Rev 74 (1994) 323-364
    • (1994) Physiol Rev , vol.74 , pp. 323-364
    • Dampney, R.A.1
  • 34
    • 0017192617 scopus 로고
    • Pulmonary angiotensin-converting enzyme antienzyme antibody
    • Das M., and Soffer R.L. Pulmonary angiotensin-converting enzyme antienzyme antibody. Biochemistry 15 (1976) 5088-5094
    • (1976) Biochemistry , vol.15 , pp. 5088-5094
    • Das, M.1    Soffer, R.L.2
  • 35
    • 0033824138 scopus 로고    scopus 로고
    • International union of pharmacology. XXIII. The angiotensin II receptors
    • de Gasparo M., Catt K.J., Inagami T., Wright J.W., and Unger T. International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev 52 (2000) 415-472
    • (2000) Pharmacol Rev , vol.52 , pp. 415-472
    • de Gasparo, M.1    Catt, K.J.2    Inagami, T.3    Wright, J.W.4    Unger, T.5
  • 36
    • 0034784818 scopus 로고    scopus 로고
    • The hypothalamus and hypertension
    • de Wardener H.E. The hypothalamus and hypertension. Physiol Rev 81 (2001) 1599-1658
    • (2001) Physiol Rev , vol.81 , pp. 1599-1658
    • de Wardener, H.E.1
  • 37
    • 0020545825 scopus 로고
    • Angiotensinogen is related to the antitrypsin-antithrombin-ovalbumin family
    • Doolittle R.F. Angiotensinogen is related to the antitrypsin-antithrombin-ovalbumin family. Science 222 (1983) 417-419
    • (1983) Science , vol.222 , pp. 417-419
    • Doolittle, R.F.1
  • 38
    • 0033912454 scopus 로고    scopus 로고
    • The sympathetic system and hypertension
    • Esler M. The sympathetic system and hypertension. Am J Hypertens 13 (2000) 99S-105S
    • (2000) Am J Hypertens , vol.13
    • Esler, M.1
  • 39
    • 46449118638 scopus 로고    scopus 로고
    • Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats
    • Feldman D.L., Jin L., Xuan H., Contrepas A., Zhou Y., Webb R.L., et al. Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats. Hypertension 52 (2008) 130-136
    • (2008) Hypertension , vol.52 , pp. 130-136
    • Feldman, D.L.1    Jin, L.2    Xuan, H.3    Contrepas, A.4    Zhou, Y.5    Webb, R.L.6
  • 40
    • 39749098706 scopus 로고    scopus 로고
    • Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide
    • Feldt S., et al. Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. Hypertension 51 (2008) 682-688
    • (2008) Hypertension , vol.51 , pp. 682-688
    • Feldt, S.1
  • 41
    • 42249089770 scopus 로고    scopus 로고
    • The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling
    • Feldt S., Maschke U., Dechend R., Luft F.C., and Muller D.N. The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling. J Am Soc Nephrol 19 (2008) 743-748
    • (2008) J Am Soc Nephrol , vol.19 , pp. 743-748
    • Feldt, S.1    Maschke, U.2    Dechend, R.3    Luft, F.C.4    Muller, D.N.5
  • 42
    • 33745162185 scopus 로고    scopus 로고
    • Role of the renin-angiotensin-aldosterone system and proinflammatory mediators in cardiovascular disease
    • Ferrario C.M., and Strawn W.B. Role of the renin-angiotensin-aldosterone system and proinflammatory mediators in cardiovascular disease. Am J Cardiol 98 (2006) 121-128
    • (2006) Am J Cardiol , vol.98 , pp. 121-128
    • Ferrario, C.M.1    Strawn, W.B.2
  • 44
    • 7244246886 scopus 로고    scopus 로고
    • Brain angiotensin-converting enzyme activity and autonomic regulation in heart failure
    • Francis J., Wei S.G., Weiss R.M., and Felder R.B. Brain angiotensin-converting enzyme activity and autonomic regulation in heart failure. Am J Physiol Heart Circ Physiol 287 (2004) H2138-2146
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Francis, J.1    Wei, S.G.2    Weiss, R.M.3    Felder, R.B.4
  • 45
    • 0020608530 scopus 로고
    • Angiotensin synthesis in the brain and increased turnover in hypertensive rats
    • Ganten D., Hermann K., Bayer C., Unger T., and Lang R.E. Angiotensin synthesis in the brain and increased turnover in hypertensive rats. Science 221 (1983) 869-871
    • (1983) Science , vol.221 , pp. 869-871
    • Ganten, D.1    Hermann, K.2    Bayer, C.3    Unger, T.4    Lang, R.E.5
  • 47
    • 0026753520 scopus 로고
    • Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes
    • Ganten D., Wagner J., Zeh K., Bader M., Michel J.B., Paul M., et al. Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes. Proc Natl Acad Sci U S A 89 (1992) 7806-7810
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 7806-7810
    • Ganten, D.1    Wagner, J.2    Zeh, K.3    Bader, M.4    Michel, J.B.5    Paul, M.6
  • 48
    • 0027976514 scopus 로고
    • Bovine tyrosine hydroxylase gene-promoter regions involved in basal and angiotensin II-stimulated expression in nontransformed adrenal medullary cells
    • Goc A., and Stachowiak M.K. Bovine tyrosine hydroxylase gene-promoter regions involved in basal and angiotensin II-stimulated expression in nontransformed adrenal medullary cells. J Neurochem 62 (1994) 834-843
    • (1994) J Neurochem , vol.62 , pp. 834-843
    • Goc, A.1    Stachowiak, M.K.2
  • 49
    • 0023718598 scopus 로고
    • Baroreceptor-mediated suppression of osmotically stimulated vasopressin in normal humans
    • Goldsmith S.R. Baroreceptor-mediated suppression of osmotically stimulated vasopressin in normal humans. J Appl Physiol 65 (1988) 1226-1230
    • (1988) J Appl Physiol , vol.65 , pp. 1226-1230
    • Goldsmith, S.R.1
  • 50
    • 0028365310 scopus 로고
    • Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
    • Griendling K.K., Minieri C.A., Ollerenshaw J.D., and Alexander R.W. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 74 (1994) 1141-1148
    • (1994) Circ Res , vol.74 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3    Alexander, R.W.4
  • 51
    • 0032126920 scopus 로고    scopus 로고
    • Redox control of vascular smooth muscle proliferation
    • Griendling K.K., and Ushio-Fukai M. Redox control of vascular smooth muscle proliferation. J Lab Clin Med 132 (1998) 9-15
    • (1998) J Lab Clin Med , vol.132 , pp. 9-15
    • Griendling, K.K.1    Ushio-Fukai, M.2
  • 52
    • 33745712914 scopus 로고    scopus 로고
    • The sympathetic control of blood pressure
    • Guyenet P.G. The sympathetic control of blood pressure. Nat Rev Neurosci 7 (2006) 335-346
    • (2006) Nat Rev Neurosci , vol.7 , pp. 335-346
    • Guyenet, P.G.1
  • 53
    • 0025817650 scopus 로고
    • Blood pressure control-special role of the kidneys and body fluids
    • Guyton A.C. Blood pressure control-special role of the kidneys and body fluids. Science 252 (1991) 1813-1816
    • (1991) Science , vol.252 , pp. 1813-1816
    • Guyton, A.C.1
  • 54
    • 0027333008 scopus 로고
    • Antisense inhibition of AT1 receptor mRNA and angiotensinogen mRNA in the brain of spontaneously hypertensive rats reduces hypertension of neurogenic origin
    • Gyurko R., Wielbo D., and Phillips M.I. Antisense inhibition of AT1 receptor mRNA and angiotensinogen mRNA in the brain of spontaneously hypertensive rats reduces hypertension of neurogenic origin. Regul Pept 49 (1993) 167-174
    • (1993) Regul Pept , vol.49 , pp. 167-174
    • Gyurko, R.1    Wielbo, D.2    Phillips, M.I.3
  • 55
    • 0022516143 scopus 로고
    • Cerebroventricular and intravascular metabolism of [125I]angiotensins in rat
    • Harding J.W., Yoshida M.S., Dilts R.P., Woods T.M., and Wright J.W. Cerebroventricular and intravascular metabolism of [125I]angiotensins in rat. J Neurochem 46 (1986) 1292-1297
    • (1986) J Neurochem , vol.46 , pp. 1292-1297
    • Harding, J.W.1    Yoshida, M.S.2    Dilts, R.P.3    Woods, T.M.4    Wright, J.W.5
  • 56
    • 0028301777 scopus 로고
    • Comparative studies on species-specific reactivity between renin and angiotensinogen
    • Hatae T., Takimoto E., Murakami K., and Fukamizu A. Comparative studies on species-specific reactivity between renin and angiotensinogen. Mol Cell Biochem 131 (1994) 43-47
    • (1994) Mol Cell Biochem , vol.131 , pp. 43-47
    • Hatae, T.1    Takimoto, E.2    Murakami, K.3    Fukamizu, A.4
  • 57
    • 0000319711 scopus 로고
    • Differentiation between two forms of angiotonin by means of spirally cut strips of rabbit aorta
    • Helmer O.M. Differentiation between two forms of angiotonin by means of spirally cut strips of rabbit aorta. Am J Physiol 188 (1957) 571-577
    • (1957) Am J Physiol , vol.188 , pp. 571-577
    • Helmer, O.M.1
  • 59
    • 0021729899 scopus 로고
    • Angiotensin biosynthesis and concentrations in brain of normotensive and hypertensive rats
    • Hermann K., McDonald W., Unger T., Lang R.E., and Ganten D. Angiotensin biosynthesis and concentrations in brain of normotensive and hypertensive rats. J Physiol (Paris) 79 (1984) 471-480
    • (1984) J Physiol (Paris) , vol.79 , pp. 471-480
    • Hermann, K.1    McDonald, W.2    Unger, T.3    Lang, R.E.4    Ganten, D.5
  • 60
    • 0030779799 scopus 로고    scopus 로고
    • Role of angiotensin II receptor subtypes in mediating the sympathoexcitatory effects of exogenous and endogenous angiotensin peptides in the rostral ventrolateral medulla of the rabbit
    • Hirooka Y., Potts P.D., and Dampney R.A.L. Role of angiotensin II receptor subtypes in mediating the sympathoexcitatory effects of exogenous and endogenous angiotensin peptides in the rostral ventrolateral medulla of the rabbit. Brain Res 772 (1997) 107
    • (1997) Brain Res , vol.772 , pp. 107
    • Hirooka, Y.1    Potts, P.D.2    Dampney, R.A.L.3
  • 61
    • 0026612790 scopus 로고
    • The role of angiotensin, AT1 and AT2 receptors in the pressor, drinking and vasopressin responses to central angiotensin
    • Hogarty D.C., Speakman E.A., Puig V., and Phillips M.I. The role of angiotensin, AT1 and AT2 receptors in the pressor, drinking and vasopressin responses to central angiotensin. Brain Res 586 (1992) 289-294
    • (1992) Brain Res , vol.586 , pp. 289-294
    • Hogarty, D.C.1    Speakman, E.A.2    Puig, V.3    Phillips, M.I.4
  • 62
    • 0036081935 scopus 로고    scopus 로고
    • Expression of angiotensin II type 1 (AT1) receptor in the rostral ventrolateral medulla in rats
    • Hu L., Zhu D.-N., Yu Z., Wang J.Q., Sun Z.-J., and Yao T. Expression of angiotensin II type 1 (AT1) receptor in the rostral ventrolateral medulla in rats. J Appl Physiol 92 (2002) 2153-2161
    • (2002) J Appl Physiol , vol.92 , pp. 2153-2161
    • Hu, L.1    Zhu, D.-N.2    Yu, Z.3    Wang, J.Q.4    Sun, Z.-J.5    Yao, T.6
  • 63
    • 48249139468 scopus 로고    scopus 로고
    • Aldosterone and TGF-beta1 synergistically increase PAI-1 and decrease matrix degradation in rat renal mesangial and fibroblast cells
    • Huang W., Xu C., Kahng K.W., Noble N.A., Border W.A., and Huang Y. Aldosterone and TGF-beta1 synergistically increase PAI-1 and decrease matrix degradation in rat renal mesangial and fibroblast cells. Am J Physiol Renal Physiol 294 (2008) F1287-1295
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Huang, W.1    Xu, C.2    Kahng, K.W.3    Noble, N.A.4    Border, W.A.5    Huang, Y.6
  • 64
    • 34347350179 scopus 로고    scopus 로고
    • Renin-stimulated TGF-beta1 expression is regulated by a mitogen-activated protein kinase in mesangial cells
    • Huang Y., Noble N.A., Zhang J., Xu C., and Border W.A. Renin-stimulated TGF-beta1 expression is regulated by a mitogen-activated protein kinase in mesangial cells. Kidney Int 72 (2007) 45-52
    • (2007) Kidney Int , vol.72 , pp. 45-52
    • Huang, Y.1    Noble, N.A.2    Zhang, J.3    Xu, C.4    Border, W.A.5
  • 65
    • 30944469631 scopus 로고    scopus 로고
    • Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
    • Huang Y., Wongamorntham S., Kasting J., McQuillan D., Owens R.T., Yu L., et al. Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms. Kidney Int 69 (2006) 105-113
    • (2006) Kidney Int , vol.69 , pp. 105-113
    • Huang, Y.1    Wongamorntham, S.2    Kasting, J.3    McQuillan, D.4    Owens, R.T.5    Yu, L.6
  • 66
    • 0019313931 scopus 로고
    • A surprising new protein superfamily containing ovalbumin, antithrombin-III, and alpha 1-proteinase inhibitor
    • Hunt L.T., and Dayhoff M.O. A surprising new protein superfamily containing ovalbumin, antithrombin-III, and alpha 1-proteinase inhibitor. Biochem Biophys Res Commun 95 (1980) 864-871
    • (1980) Biochem Biophys Res Commun , vol.95 , pp. 864-871
    • Hunt, L.T.1    Dayhoff, M.O.2
  • 67
    • 33751081792 scopus 로고    scopus 로고
    • Response to cardiovascular effects of nonproteolytic activation of prorenin
    • Ichihara A., and Kaneshiro Y. Response to cardiovascular effects of nonproteolytic activation of prorenin. Hypertension 48 (2006) e114
    • (2006) Hypertension , vol.48
    • Ichihara, A.1    Kaneshiro, Y.2
  • 68
    • 9644283069 scopus 로고    scopus 로고
    • Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin
    • Ichihara A., Hayashi M., Kaneshiro Y., Suzuki F., Nakagawa T., Tada Y., et al. Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin. J Clin Invest 114 (2004) 1128-1135
    • (2004) J Clin Invest , vol.114 , pp. 1128-1135
    • Ichihara, A.1    Hayashi, M.2    Kaneshiro, Y.3    Suzuki, F.4    Nakagawa, T.5    Tada, Y.6
  • 69
    • 33646160993 scopus 로고    scopus 로고
    • Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension
    • Ichihara A., Kaneshiro Y., Takemitsu T., Sakoda M., Suzuki F., Nakagawa T., et al. Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension. Hypertension 47 (2006) 894-900
    • (2006) Hypertension , vol.47 , pp. 894-900
    • Ichihara, A.1    Kaneshiro, Y.2    Takemitsu, T.3    Sakoda, M.4    Suzuki, F.5    Nakagawa, T.6
  • 70
    • 33745824649 scopus 로고    scopus 로고
    • Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice
    • Ichihara A., Suzuki F., Nakagawa T., Kaneshiro Y., Takemitsu T., Sakoda M., et al. Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice. J Am Soc Nephrol 17 (2006) 1950-1961
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1950-1961
    • Ichihara, A.1    Suzuki, F.2    Nakagawa, T.3    Kaneshiro, Y.4    Takemitsu, T.5    Sakoda, M.6
  • 71
    • 0025056511 scopus 로고
    • In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system
    • Ingelfinger J.R., Zuo W.M., Fon E.A., Ellison K.E., and Dzau V.J. In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system. J Clin Invest 85 (1990) 417-423
    • (1990) J Clin Invest , vol.85 , pp. 417-423
    • Ingelfinger, J.R.1    Zuo, W.M.2    Fon, E.A.3    Ellison, K.E.4    Dzau, V.J.5
  • 72
    • 0029827490 scopus 로고    scopus 로고
    • Blockade of angiotensin receptors in rat rostral ventrolateral medulla removes excitatory vasomotor tone
    • Ito S., and Sved A.F. Blockade of angiotensin receptors in rat rostral ventrolateral medulla removes excitatory vasomotor tone. Am J Physiol 270 (1996) R1317-1323
    • (1996) Am J Physiol , vol.270
    • Ito, S.1    Sved, A.F.2
  • 73
    • 0034537384 scopus 로고    scopus 로고
    • Pharmacological profile of depressor response elicited by sarthran in rat ventrolateral medulla
    • Ito S., and Sved A.F. Pharmacological profile of depressor response elicited by sarthran in rat ventrolateral medulla. Am J Physiol Heart Circ Physiol 279 (2000) H2961-2966
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Ito, S.1    Sved, A.F.2
  • 74
    • 0037341456 scopus 로고    scopus 로고
    • Ventrolateral medulla AT1 receptors support arterial pressure in Dahl salt-sensitive rats
    • Ito S., Hiratsuka M., Komatsu K., Tsukamoto K., Kanmatsuse K., and Sved A.F. Ventrolateral medulla AT1 receptors support arterial pressure in Dahl salt-sensitive rats. Hypertension 41 (2003) 744-750
    • (2003) Hypertension , vol.41 , pp. 744-750
    • Ito, S.1    Hiratsuka, M.2    Komatsu, K.3    Tsukamoto, K.4    Kanmatsuse, K.5    Sved, A.F.6
  • 75
    • 0036771845 scopus 로고    scopus 로고
    • Ventrolateral medulla AT1 receptors support blood pressure in hypertensive rats
    • Ito S., Komatsu K., Tsukamoto K., Kanmatsuse K., and Sved A.F. Ventrolateral medulla AT1 receptors support blood pressure in hypertensive rats. Hypertension 40 (2002) 552-559
    • (2002) Hypertension , vol.40 , pp. 552-559
    • Ito, S.1    Komatsu, K.2    Tsukamoto, K.3    Kanmatsuse, K.4    Sved, A.F.5
  • 77
    • 0037409309 scopus 로고    scopus 로고
    • Local renin-angiotensin systems: the unanswered questions
    • Jan Danser A.H. Local renin-angiotensin systems: the unanswered questions. Int J Biochem Cell Biol 35 (2003) 759
    • (2003) Int J Biochem Cell Biol , vol.35 , pp. 759
    • Jan Danser, A.H.1
  • 78
    • 27444447364 scopus 로고    scopus 로고
    • Renin, prorenin and the putative (pro)renin receptor
    • Jan Danser A.H., and Deinum J. Renin, prorenin and the putative (pro)renin receptor. Hypertension 46 (2005) 1069-1076
    • (2005) Hypertension , vol.46 , pp. 1069-1076
    • Jan Danser, A.H.1    Deinum, J.2
  • 80
    • 34249881320 scopus 로고    scopus 로고
    • Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats
    • Kaneshiro Y., Ichihara A., Sakoda M., Takemitsu T., Nabi A.H., Uddin M.N., et al. Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats. J Am Soc Nephrol 18 (2007) 1789-1795
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1789-1795
    • Kaneshiro, Y.1    Ichihara, A.2    Sakoda, M.3    Takemitsu, T.4    Nabi, A.H.5    Uddin, M.N.6
  • 81
    • 43549089723 scopus 로고    scopus 로고
    • Altered central catecholaminergic transmission and cardiovascular disease
    • Kasparov S., and Teschemacher A.G. Altered central catecholaminergic transmission and cardiovascular disease. Exp Physiol 93 (2008) 725-740
    • (2008) Exp Physiol , vol.93 , pp. 725-740
    • Kasparov, S.1    Teschemacher, A.G.2
  • 83
    • 34748859681 scopus 로고    scopus 로고
    • The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease
    • Kobori H., Nangaku M., Navar L.G., and Nishiyama A. The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev 59 (2007) 251-287
    • (2007) Pharmacol Rev , vol.59 , pp. 251-287
    • Kobori, H.1    Nangaku, M.2    Navar, L.G.3    Nishiyama, A.4
  • 84
    • 0023897045 scopus 로고
    • Angiotensinogen gene expression in neuronal and glial cells in primary cultures of rat brain
    • Kumar A., Rassoli A., and Raizada M.K. Angiotensinogen gene expression in neuronal and glial cells in primary cultures of rat brain. J Neurosci Res 19 (1988) 287-290
    • (1988) J Neurosci Res , vol.19 , pp. 287-290
    • Kumar, A.1    Rassoli, A.2    Raizada, M.K.3
  • 85
    • 2342479957 scopus 로고    scopus 로고
    • Adjacent expression of renin and angiotensinogen in the rostral ventrolateral medulla using a dual-reporter transgenic model
    • Lavoie J.L., Cassell M.D., Gross K.W., and Sigmund C.D. Adjacent expression of renin and angiotensinogen in the rostral ventrolateral medulla using a dual-reporter transgenic model. Hypertension 43 (2004) 1116-1119
    • (2004) Hypertension , vol.43 , pp. 1116-1119
    • Lavoie, J.L.1    Cassell, M.D.2    Gross, K.W.3    Sigmund, C.D.4
  • 86
    • 1842587534 scopus 로고    scopus 로고
    • Localization of renin expressing cells in the brain, by use of a REN-eGFP transgenic model
    • Lavoie J.L., Cassell M.D., Gross K.W., and Sigmund C.D. Localization of renin expressing cells in the brain, by use of a REN-eGFP transgenic model. Physiol Genomics 16 (2004) 240-246
    • (2004) Physiol Genomics , vol.16 , pp. 240-246
    • Lavoie, J.L.1    Cassell, M.D.2    Gross, K.W.3    Sigmund, C.D.4
  • 87
    • 0037155772 scopus 로고    scopus 로고
    • Brain-selective overexpression of angiotensin (AT1) receptors causes enhanced cardiovascular sensitivity in transgenic mice
    • Lazartigues E., Dunlay S.M., Loihl A.K., Sinnayah P., Lang J.A., Espelund J.J., et al. Brain-selective overexpression of angiotensin (AT1) receptors causes enhanced cardiovascular sensitivity in transgenic mice. Circ Res 90 (2002) 617-624
    • (2002) Circ Res , vol.90 , pp. 617-624
    • Lazartigues, E.1    Dunlay, S.M.2    Loihl, A.K.3    Sinnayah, P.4    Lang, J.A.5    Espelund, J.J.6
  • 89
    • 0038452698 scopus 로고    scopus 로고
    • Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition
    • Li D.P., Chen S.R., and Pan H.L. Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition. J Neurosci 23 (2003) 5041-5049
    • (2003) J Neurosci , vol.23 , pp. 5041-5049
    • Li, D.P.1    Chen, S.R.2    Pan, H.L.3
  • 90
    • 0029670960 scopus 로고    scopus 로고
    • Angiotensin II decreases a resting K+ conductance in rat bulbospinal neurons of the C1 area
    • Li Y.W., and Guyenet P.G. Angiotensin II decreases a resting K+ conductance in rat bulbospinal neurons of the C1 area. Circ Res 78 (1996) 274-282
    • (1996) Circ Res , vol.78 , pp. 274-282
    • Li, Y.W.1    Guyenet, P.G.2
  • 91
    • 0027244387 scopus 로고
    • Subfornical organ efferents to paraventricular nucleus utilize angiotensin as a neurotransmitter
    • Li Z., and Ferguson A.V. Subfornical organ efferents to paraventricular nucleus utilize angiotensin as a neurotransmitter. Am J Physiol 265 (1993) R302-309
    • (1993) Am J Physiol , vol.265
    • Li, Z.1    Ferguson, A.V.2
  • 92
    • 0035936780 scopus 로고    scopus 로고
    • Molecular mechanisms of human hypertension
    • Lifton R.P., Gharavi A.G., and Geller D.S. Molecular mechanisms of human hypertension. Cell 104 (2001) 545-556
    • (2001) Cell , vol.104 , pp. 545-556
    • Lifton, R.P.1    Gharavi, A.G.2    Geller, D.S.3
  • 93
    • 0021671104 scopus 로고
    • Angiotensin II immunoreactive pathways in the central nervous system of the rat: evidence for a projection from the subfornical organ to the paraventricular nucleus of the hypothalamus
    • Lind R.W., Swanson L.W., and Ganten D. Angiotensin II immunoreactive pathways in the central nervous system of the rat: evidence for a projection from the subfornical organ to the paraventricular nucleus of the hypothalamus. Clin Exp Hypertens A 6 (1984) 1915-1920
    • (1984) Clin Exp Hypertens A , vol.6 , pp. 1915-1920
    • Lind, R.W.1    Swanson, L.W.2    Ganten, D.3
  • 94
    • 0035072529 scopus 로고    scopus 로고
    • A view of renin in the brain
    • Lippoldt A., Fuxe K., and Luft F.C. A view of renin in the brain. J Mol Med 79 (2001) 71-73
    • (2001) J Mol Med , vol.79 , pp. 71-73
    • Lippoldt, A.1    Fuxe, K.2    Luft, F.C.3
  • 96
    • 0032514215 scopus 로고    scopus 로고
    • Regulation of angiotensin II-induced neuromodulation by MARCKS in brain neurons
    • Lu D., Yang H., Lenox R.H., and Raizada M.K. Regulation of angiotensin II-induced neuromodulation by MARCKS in brain neurons. J Cell Biol 142 (1998) 217-227
    • (1998) J Cell Biol , vol.142 , pp. 217-227
    • Lu, D.1    Yang, H.2    Lenox, R.H.3    Raizada, M.K.4
  • 97
    • 0030470183 scopus 로고    scopus 로고
    • Angiotensin II regulation of neuromodulation: downstream signaling mechanism from activation of mitogen-activated protein kinase
    • Lu D., Yang H., and Raizada M.K. Angiotensin II regulation of neuromodulation: downstream signaling mechanism from activation of mitogen-activated protein kinase. J Cell Biol 135 (1996) 1609-1617
    • (1996) J Cell Biol , vol.135 , pp. 1609-1617
    • Lu, D.1    Yang, H.2    Raizada, M.K.3
  • 98
    • 0031595096 scopus 로고    scopus 로고
    • AT1 receptor-mediated nuclear translocation of Raf-1 in brain neurons
    • Lu D., Yang H., and Raizada M.K. AT1 receptor-mediated nuclear translocation of Raf-1 in brain neurons. J Neurochem 70 (1998) 424-427
    • (1998) J Neurochem , vol.70 , pp. 424-427
    • Lu, D.1    Yang, H.2    Raizada, M.K.3
  • 99
    • 0030070394 scopus 로고    scopus 로고
    • Regulation of norepinephrine transport system by angiotensin II in neuronal cultures of normotensive and spontaneously hypertensive rat brains
    • Lu D., Yu K., Paddy M.R., Rowland N.E., and Raizada M.K. Regulation of norepinephrine transport system by angiotensin II in neuronal cultures of normotensive and spontaneously hypertensive rat brains. Endocrinology 137 (1996) 763-772
    • (1996) Endocrinology , vol.137 , pp. 763-772
    • Lu, D.1    Yu, K.2    Paddy, M.R.3    Rowland, N.E.4    Raizada, M.K.5
  • 100
    • 0021889169 scopus 로고
    • Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications
    • Luetscher J.A., Kraemer F.B., Wilson D.M., Schwartz H.C., and Bryer-Ash M. Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications. N Engl J Med 312 (1985) 1412-1417
    • (1985) N Engl J Med , vol.312 , pp. 1412-1417
    • Luetscher, J.A.1    Kraemer, F.B.2    Wilson, D.M.3    Schwartz, H.C.4    Bryer-Ash, M.5
  • 101
    • 34548823532 scopus 로고    scopus 로고
    • Vasopressin, urine concentration, and hypertension: a new perspective on an old story
    • Luft F.C. Vasopressin, urine concentration, and hypertension: a new perspective on an old story. Clin J Am Soc Nephrol 2 (2007) 196-197
    • (2007) Clin J Am Soc Nephrol , vol.2 , pp. 196-197
    • Luft, F.C.1
  • 102
    • 0035851213 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase isoforms selectively couple receptors to vascular L-type Ca(2+) channels
    • Macrez N., Mironneau C., Carricaburu V., Quignard J.F., Babich A., Czupalla C., et al. Phosphoinositide 3-kinase isoforms selectively couple receptors to vascular L-type Ca(2+) channels. Circ Res 89 (2001) 692-699
    • (2001) Circ Res , vol.89 , pp. 692-699
    • Macrez, N.1    Mironneau, C.2    Carricaburu, V.3    Quignard, J.F.4    Babich, A.5    Czupalla, C.6
  • 103
    • 0019164781 scopus 로고
    • Supraoptic neurones of rat hypothalamus are osmosensitive
    • Mason W.T. Supraoptic neurones of rat hypothalamus are osmosensitive. Nature 287 (1980) 154-157
    • (1980) Nature , vol.287 , pp. 154-157
    • Mason, W.T.1
  • 106
    • 0030049446 scopus 로고    scopus 로고
    • Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes
    • Merrill D.C., Thompson M.W., Carney C.L., Granwehr B.P., Schlager G., Robillard G.E., et al. Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes. J Clin Invest 97 (1996) 1047-1055
    • (1996) J Clin Invest , vol.97 , pp. 1047-1055
    • Merrill, D.C.1    Thompson, M.W.2    Carney, C.L.3    Granwehr, B.P.4    Schlager, G.5    Robillard, G.E.6
  • 109
    • 0036552412 scopus 로고    scopus 로고
    • Angiotensin mutant mice: a focus on the brain renin-angiotensin system
    • Morimoto S., and Sigmund C.D. Angiotensin mutant mice: a focus on the brain renin-angiotensin system. Neuropeptides 36 (2002) 194-200
    • (2002) Neuropeptides , vol.36 , pp. 194-200
    • Morimoto, S.1    Sigmund, C.D.2
  • 110
    • 0037059564 scopus 로고    scopus 로고
    • The brain renin-angiotensin system in transgenic mice carrying a highly regulated human renin transgene
    • Morimoto S., Cassell M.D., and Sigmund C.D. The brain renin-angiotensin system in transgenic mice carrying a highly regulated human renin transgene. Circ Res 90 (2002) 80-86
    • (2002) Circ Res , vol.90 , pp. 80-86
    • Morimoto, S.1    Cassell, M.D.2    Sigmund, C.D.3
  • 112
    • 0029125410 scopus 로고
    • Effects of human renin in the vasculature of rats transgenic for human angiotensinogen
    • Muller D.N., Hilgers K.F., Bohlender J., Lippoldt A., Wagner J., Fischli W., et al. Effects of human renin in the vasculature of rats transgenic for human angiotensinogen. Hypertension 26 (1995) 272-278
    • (1995) Hypertension , vol.26 , pp. 272-278
    • Muller, D.N.1    Hilgers, K.F.2    Bohlender, J.3    Lippoldt, A.4    Wagner, J.5    Fischli, W.6
  • 113
    • 39749088803 scopus 로고    scopus 로고
    • (Pro)renin receptor peptide inhibitor "handle-region" peptide does not affect hypertensive nephrosclerosis in Goldblatt rats
    • Muller D.N., Klanke B., Feldt S., Cordasic N., Hartner A., Schmieder R.E., et al. (Pro)renin receptor peptide inhibitor "handle-region" peptide does not affect hypertensive nephrosclerosis in Goldblatt rats. Hypertension 51 (2008) 676-681
    • (2008) Hypertension , vol.51 , pp. 676-681
    • Muller, D.N.1    Klanke, B.2    Feldt, S.3    Cordasic, N.4    Hartner, A.5    Schmieder, R.E.6
  • 114
    • 0025239301 scopus 로고
    • Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene
    • Mullins J.J., Peters J., and Ganten D. Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene. Nature 344 (1990) 541-544
    • (1990) Nature , vol.344 , pp. 541-544
    • Mullins, J.J.1    Peters, J.2    Ganten, D.3
  • 115
    • 33750600468 scopus 로고    scopus 로고
    • Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system
    • Nabi A.H., Kageshima A., Uddin M.N., Nakagawa T., Park E.Y., and Suzuki F. Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system. Int J Mol Med 18 (2006) 483-488
    • (2006) Int J Mol Med , vol.18 , pp. 483-488
    • Nabi, A.H.1    Kageshima, A.2    Uddin, M.N.3    Nakagawa, T.4    Park, E.Y.5    Suzuki, F.6
  • 116
    • 0032820248 scopus 로고    scopus 로고
    • Activation of the brain angiotensin system by in vivo human angiotensin-converting enzyme gene transfer in rats
    • Nakamura S., Moriguchi A., Morishita R., Yamada K., Nishii T., Tomita N., et al. Activation of the brain angiotensin system by in vivo human angiotensin-converting enzyme gene transfer in rats. Hypertension 34 (1999) 302-308
    • (1999) Hypertension , vol.34 , pp. 302-308
    • Nakamura, S.1    Moriguchi, A.2    Morishita, R.3    Yamada, K.4    Nishii, T.5    Tomita, N.6
  • 117
    • 33646501526 scopus 로고    scopus 로고
    • Renin/prorenin receptors
    • Nguyen G. Renin/prorenin receptors. Kidney Int 69 (2006) 1503
    • (2006) Kidney Int , vol.69 , pp. 1503
    • Nguyen, G.1
  • 118
    • 40649124722 scopus 로고    scopus 로고
    • Physiology and pharmacology of the (pro)renin receptor
    • Nguyen G., and Contrepas A. Physiology and pharmacology of the (pro)renin receptor. Curr Opinion Pharmacol 8 (2008) 127
    • (2008) Curr Opinion Pharmacol , vol.8 , pp. 127
    • Nguyen, G.1    Contrepas, A.2
  • 119
    • 43449090079 scopus 로고    scopus 로고
    • The (pro)renin receptors
    • Nguyen G., and Contrepas A. The (pro)renin receptors. J Mol Med 86 (2008) 643-646
    • (2008) J Mol Med , vol.86 , pp. 643-646
    • Nguyen, G.1    Contrepas, A.2
  • 120
    • 0029853814 scopus 로고    scopus 로고
    • Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen
    • Nguyen G., Delarue F., Berrou J., Rondeau E., and Sraer J.-D. Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen. Kidney Int 50 (1996) 1897
    • (1996) Kidney Int , vol.50 , pp. 1897
    • Nguyen, G.1    Delarue, F.2    Berrou, J.3    Rondeau, E.4    Sraer, J.-D.5
  • 121
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • Nguyen G., Delarue F., Burckle C., Bouzhir L., Giller T., and Sraer J.D. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 109 (2002) 1417-1427
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3    Bouzhir, L.4    Giller, T.5    Sraer, J.D.6
  • 122
    • 0033529509 scopus 로고    scopus 로고
    • Angiotensinogen gene-activating elements regulate blood pressure in the brain
    • Nishii T., Moriguchi A., Morishita R., Yamada K., Nakamura S., Tomita N., et al. Angiotensinogen gene-activating elements regulate blood pressure in the brain. Circ Res 85 (1999) 257-263
    • (1999) Circ Res , vol.85 , pp. 257-263
    • Nishii, T.1    Moriguchi, A.2    Morishita, R.3    Yamada, K.4    Nakamura, S.5    Tomita, N.6
  • 123
    • 34547693066 scopus 로고    scopus 로고
    • Role of "handle" region of prorenin prosegment in the non-proteolytic activation of prorenin by binding to membrane anchored (pro)renin receptor
    • Nurun N.A., Uddin N.M., Nakagawa T., Iwata H., Ichihara A., Inagami T., et al. Role of "handle" region of prorenin prosegment in the non-proteolytic activation of prorenin by binding to membrane anchored (pro)renin receptor. Front Biosci 12 (2007) 4810-4817
    • (2007) Front Biosci , vol.12 , pp. 4810-4817
    • Nurun, N.A.1    Uddin, N.M.2    Nakagawa, T.3    Iwata, H.4    Ichihara, A.5    Inagami, T.6
  • 125
    • 4544274907 scopus 로고    scopus 로고
    • Brain angiotensin II and synaptic transmission
    • Pan H.L. Brain angiotensin II and synaptic transmission. Neuroscientist 10 (2004) 422-431
    • (2004) Neuroscientist , vol.10 , pp. 422-431
    • Pan, H.L.1
  • 126
    • 0023855091 scopus 로고
    • Quantification of renin mRNA in various mouse tissues by a novel solution hybridization assay
    • Paul M., Wagner D., Metzger R., Ganten D., Lang R.E., Suzuki F., et al. Quantification of renin mRNA in various mouse tissues by a novel solution hybridization assay. J Hypertens 6 (1988) 247-252
    • (1988) J Hypertens , vol.6 , pp. 247-252
    • Paul, M.1    Wagner, D.2    Metzger, R.3    Ganten, D.4    Lang, R.E.5    Suzuki, F.6
  • 127
    • 0023793081 scopus 로고
    • Brain angiotensin in the developing spontaneously hypertensive rat
    • Phillips M.I., and Kimura B. Brain angiotensin in the developing spontaneously hypertensive rat. J Hypertens 6 (1988) 607-612
    • (1988) J Hypertens , vol.6 , pp. 607-612
    • Phillips, M.I.1    Kimura, B.2
  • 128
    • 0017697211 scopus 로고
    • Lowering of hypertension by central saralasin in the absence of plasma renin
    • Phillips M.I., Mann J.F., Haebara H., Hoffman W.E., Dietz R., Schelling P., et al. Lowering of hypertension by central saralasin in the absence of plasma renin. Nature 270 (1977) 445-447
    • (1977) Nature , vol.270 , pp. 445-447
    • Phillips, M.I.1    Mann, J.F.2    Haebara, H.3    Hoffman, W.E.4    Dietz, R.5    Schelling, P.6
  • 129
    • 0027473892 scopus 로고
    • Immunohistochemical mapping of angiotensin AT1 receptors in the brain
    • Phillips M.I., Shen L., Richards E.M., and Raizada M.K. Immunohistochemical mapping of angiotensin AT1 receptors in the brain. Regul Pept 44 (1993) 95-107
    • (1993) Regul Pept , vol.44 , pp. 95-107
    • Phillips, M.I.1    Shen, L.2    Richards, E.M.3    Raizada, M.K.4
  • 130
    • 0028997101 scopus 로고
    • Co-localization of angiotensin II and gamma-aminobutyric acid in axon terminals in the rat subfornical organ
    • Pickel V.M., and Chan J. Co-localization of angiotensin II and gamma-aminobutyric acid in axon terminals in the rat subfornical organ. Neurosci Lett 193 (1995) 89-92
    • (1995) Neurosci Lett , vol.193 , pp. 89-92
    • Pickel, V.M.1    Chan, J.2
  • 131
    • 0022557065 scopus 로고
    • Dual peroxidase and colloidal gold-labeling study of angiotensin converting enzyme and angiotensin-like immunoreactivity in the rat subfornical organ
    • Pickel V.M., Chan J., and Ganten D. Dual peroxidase and colloidal gold-labeling study of angiotensin converting enzyme and angiotensin-like immunoreactivity in the rat subfornical organ. J Neurosci 6 (1986) 2457-2469
    • (1986) J Neurosci , vol.6 , pp. 2457-2469
    • Pickel, V.M.1    Chan, J.2    Ganten, D.3
  • 132
    • 20244369597 scopus 로고    scopus 로고
    • A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor
    • Ramser J., Abidi F.E., Burckle C.A., Lenski C., Toriello H., Wen G., et al. A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor. Hum Mol Genet 14 (2005) 1019-1027
    • (2005) Hum Mol Genet , vol.14 , pp. 1019-1027
    • Ramser, J.1    Abidi, F.E.2    Burckle, C.A.3    Lenski, C.4    Toriello, H.5    Wen, G.6
  • 133
    • 0026515446 scopus 로고
    • Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression
    • Rao G.N., and Berk B.C. Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression. Circ Res 70 (1992) 593-599
    • (1992) Circ Res , vol.70 , pp. 593-599
    • Rao, G.N.1    Berk, B.C.2
  • 134
    • 0035347330 scopus 로고    scopus 로고
    • Angiotensin III: a central regulator of vasopressin release and blood pressure
    • Reaux A., Fournie-Zaluski M.C., and Llorens-Cortes C. Angiotensin III: a central regulator of vasopressin release and blood pressure. Trends Endocrinol Metab 12 (2001) 157-162
    • (2001) Trends Endocrinol Metab , vol.12 , pp. 157-162
    • Reaux, A.1    Fournie-Zaluski, M.C.2    Llorens-Cortes, C.3
  • 135
    • 0023903227 scopus 로고
    • The renin-angiotensin system in the rat brain. Immunocytochemical localization of angiotensinogen in glial cells and neurons
    • Richoux J.P., Bouhnik J., Clauser E., and Corvol P. The renin-angiotensin system in the rat brain. Immunocytochemical localization of angiotensinogen in glial cells and neurons. Histochemistry 89 (1988) 323-331
    • (1988) Histochemistry , vol.89 , pp. 323-331
    • Richoux, J.P.1    Bouhnik, J.2    Clauser, E.3    Corvol, P.4
  • 136
    • 0025020166 scopus 로고
    • The renin-angiotensin system in different stages of spontaneous hypertension in the rat (S H R)
    • Ruiz P., Basso N., Cannata M.A., and Taquini A.C. The renin-angiotensin system in different stages of spontaneous hypertension in the rat (S H R). Clin Exp Hypertens A 12 (1990) 63-81
    • (1990) Clin Exp Hypertens A , vol.12 , pp. 63-81
    • Ruiz, P.1    Basso, N.2    Cannata, M.A.3    Taquini, A.C.4
  • 137
    • 23944500881 scopus 로고    scopus 로고
    • Brain angiotensin II: new developments, unanswered questions and therapeutic opportunities
    • Saavedra J.M. Brain angiotensin II: new developments, unanswered questions and therapeutic opportunities. Cell Mol Neurobiol 25 (2005) 485-512
    • (2005) Cell Mol Neurobiol , vol.25 , pp. 485-512
    • Saavedra, J.M.1
  • 139
    • 33845608395 scopus 로고    scopus 로고
    • A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein
    • Schefe J.H., Menk M., Reinemund J., Effertz K., Hobbs R.M., Pandolfi P.P., et al. A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein. Circ Res 99 (2006) 1355-1366
    • (2006) Circ Res , vol.99 , pp. 1355-1366
    • Schefe, J.H.1    Menk, M.2    Reinemund, J.3    Effertz, K.4    Hobbs, R.M.5    Pandolfi, P.P.6
  • 141
    • 0033616721 scopus 로고    scopus 로고
    • Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen
    • Schinke M., Baltatu O., Bohm M., Peters J., Rascher W., Bricca G., et al. Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen. Proc Natl Acad Sci U S A 96 (1999) 3975-3980
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 3975-3980
    • Schinke, M.1    Baltatu, O.2    Bohm, M.3    Peters, J.4    Rascher, W.5    Bricca, G.6
  • 142
    • 0842289476 scopus 로고    scopus 로고
    • Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and angiotensin neuromodulation
    • Schlaich M.P., Lambert E., Kaye D.M., Krozowski Z., Campbell D.J., Lambert G., et al. Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and angiotensin neuromodulation. Hypertension 43 (2004) 169-175
    • (2004) Hypertension , vol.43 , pp. 169-175
    • Schlaich, M.P.1    Lambert, E.2    Kaye, D.M.3    Krozowski, Z.4    Campbell, D.J.5    Lambert, G.6
  • 143
    • 0029905502 scopus 로고    scopus 로고
    • Multiple protein factors interact with the cis-regulatory elements of the proximal promoter in a cell-specific manner and regulate transcription of the dopamine beta-hydroxylase gene
    • Seo H., Yang C., Kim H.S., and Kim K.S. Multiple protein factors interact with the cis-regulatory elements of the proximal promoter in a cell-specific manner and regulate transcription of the dopamine beta-hydroxylase gene. J Neurosci 16 (1996) 4102-4112
    • (1996) J Neurosci , vol.16 , pp. 4102-4112
    • Seo, H.1    Yang, C.2    Kim, H.S.3    Kim, K.S.4
  • 145
    • 42649086029 scopus 로고    scopus 로고
    • Characterization of a functional (pro)renin receptor in rat brain neurons
    • Shan Z., Cuadra A.E., Sumners C., and Raizada M.K. Characterization of a functional (pro)renin receptor in rat brain neurons. Exp Physiol 93 (2008) 701-708
    • (2008) Exp Physiol , vol.93 , pp. 701-708
    • Shan, Z.1    Cuadra, A.E.2    Sumners, C.3    Raizada, M.K.4
  • 146
    • 33750896096 scopus 로고    scopus 로고
    • Genetic ablation of angiotensinogen in the subfornical organ of the brain prevents the central angiotensinergic pressor response
    • Sinnayah P., Lazartigues E., Sakai K., Sharma R.V., Sigmund C.D., and Davisson R.L. Genetic ablation of angiotensinogen in the subfornical organ of the brain prevents the central angiotensinergic pressor response. Circ Res 99 (2006) 1125-1131
    • (2006) Circ Res , vol.99 , pp. 1125-1131
    • Sinnayah, P.1    Lazartigues, E.2    Sakai, K.3    Sharma, R.V.4    Sigmund, C.D.5    Davisson, R.L.6
  • 147
    • 0038163054 scopus 로고
    • The preparation and function of the hypertensin-converting enzyme
    • Skeggs Jr. L.T., Kahn J.R., and Shumway N.P. The preparation and function of the hypertensin-converting enzyme. J Exp Med 103 (1956) 295-299
    • (1956) J Exp Med , vol.103 , pp. 295-299
    • Skeggs Jr., L.T.1    Kahn, J.R.2    Shumway, N.P.3
  • 148
    • 0028810344 scopus 로고
    • Effects of vasopressin and aldosterone on the lateral mobility of epithelial Na+ channels in A6 renal epithelial cells
    • Smith P.R., Stoner L.C., Viggiano S.C., Angelides K.J., and Benos D.J. Effects of vasopressin and aldosterone on the lateral mobility of epithelial Na+ channels in A6 renal epithelial cells. J Membr Biol 147 (1995) 195-205
    • (1995) J Membr Biol , vol.147 , pp. 195-205
    • Smith, P.R.1    Stoner, L.C.2    Viggiano, S.C.3    Angelides, K.J.4    Benos, D.J.5
  • 149
    • 0035851221 scopus 로고    scopus 로고
    • PI3King the L-type calcium channel activation mechanism
    • Steinberg S.F. PI3King the L-type calcium channel activation mechanism. Circ Res 89 (2001) 641-644
    • (2001) Circ Res , vol.89 , pp. 641-644
    • Steinberg, S.F.1
  • 151
    • 16444380220 scopus 로고    scopus 로고
    • NAD(P)H oxidase inhibition attenuates neuronal chronotropic actions of angiotensin II
    • Sun C., Sellers K.W., Sumners C., and Raizada M.K. NAD(P)H oxidase inhibition attenuates neuronal chronotropic actions of angiotensin II. Circ Res 96 (2005) 659-666
    • (2005) Circ Res , vol.96 , pp. 659-666
    • Sun, C.1    Sellers, K.W.2    Sumners, C.3    Raizada, M.K.4
  • 152
    • 0036175502 scopus 로고    scopus 로고
    • Chronotropic action of angiotensin II in neurons via protein kinase C and CaMKII
    • Sun C., Sumners C., and Raizada M.K. Chronotropic action of angiotensin II in neurons via protein kinase C and CaMKII. Hypertension 39 (2002) 562-566
    • (2002) Hypertension , vol.39 , pp. 562-566
    • Sun, C.1    Sumners, C.2    Raizada, M.K.3
  • 153
    • 0037591344 scopus 로고    scopus 로고
    • Human prorenin has "gate and handle" regions for its non-proteolytic activation
    • Suzuki F., Hayakawa M., Nakagawa T., Nasir U.M., Ebihara A., Iwasawa A., et al. Human prorenin has "gate and handle" regions for its non-proteolytic activation. J Biol Chem 278 (2003) 22217-22222
    • (2003) J Biol Chem , vol.278 , pp. 22217-22222
    • Suzuki, F.1    Hayakawa, M.2    Nakagawa, T.3    Nasir, U.M.4    Ebihara, A.5    Iwasawa, A.6
  • 154
    • 0020645737 scopus 로고
    • Hypothalamic integration: organization of the paraventricular and supraoptic nuclei
    • Swanson L.W., and Sawchenko P.E. Hypothalamic integration: organization of the paraventricular and supraoptic nuclei. Annu Rev Neurosci 6 (1983) 269-324
    • (1983) Annu Rev Neurosci , vol.6 , pp. 269-324
    • Swanson, L.W.1    Sawchenko, P.E.2
  • 155
    • 0035691617 scopus 로고    scopus 로고
    • The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas
    • Szkudelski T. The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res 50 (2001) 537-546
    • (2001) Physiol Res , vol.50 , pp. 537-546
    • Szkudelski, T.1
  • 157
    • 0032819352 scopus 로고    scopus 로고
    • Sympathoinhibition after angiotensin receptor blockade in the rostral ventrolateral medulla is independent of glutamate and gamma-aminobutyric acid receptors
    • Tagawa T., Horiuchi J., Potts P.D., and Dampney R.A. Sympathoinhibition after angiotensin receptor blockade in the rostral ventrolateral medulla is independent of glutamate and gamma-aminobutyric acid receptors. J Auton Nerv Syst 77 (1999) 21-30
    • (1999) J Auton Nerv Syst , vol.77 , pp. 21-30
    • Tagawa, T.1    Horiuchi, J.2    Potts, P.D.3    Dampney, R.A.4
  • 159
    • 0019154043 scopus 로고
    • Augmented sympathetic nerve activity and pressor responsiveness in DOCA hypertensive rats
    • Takeda K., and Bunag R.D. Augmented sympathetic nerve activity and pressor responsiveness in DOCA hypertensive rats. Hypertension 2 (1980) 97-101
    • (1980) Hypertension , vol.2 , pp. 97-101
    • Takeda, K.1    Bunag, R.D.2
  • 160
    • 9344227303 scopus 로고    scopus 로고
    • Tissue-specific regulation of angiotensinogen gene expression in spontaneously hypertensive rats
    • Tamura K., Umemura S., Nyui N., Yamakawa T., Yamaguchi S., Ishigami T., et al. Tissue-specific regulation of angiotensinogen gene expression in spontaneously hypertensive rats. Hypertension 27 (1996) 1216-1223
    • (1996) Hypertension , vol.27 , pp. 1216-1223
    • Tamura, K.1    Umemura, S.2    Nyui, N.3    Yamakawa, T.4    Yamaguchi, S.5    Ishigami, T.6
  • 161
    • 1942501668 scopus 로고    scopus 로고
    • Increases in brain and cardiac AT1 receptor and ACE densities after myocardial infarct in rats
    • Tan J., Wang H., and Leenen F.H. Increases in brain and cardiac AT1 receptor and ACE densities after myocardial infarct in rats. Am J Physiol Heart Circ Physiol 286 (2004) H1665-1671
    • (2004) Am J Physiol Heart Circ Physiol , vol.286
    • Tan, J.1    Wang, H.2    Leenen, F.H.3
  • 162
    • 0026644264 scopus 로고
    • Angiotensinogen is secreted by pure rat neuronal cell cultures
    • Thomas W.G., Greenland K.J., Shinkel T.A., and Sernia C. Angiotensinogen is secreted by pure rat neuronal cell cultures. Brain Res 588 (1992) 191-200
    • (1992) Brain Res , vol.588 , pp. 191-200
    • Thomas, W.G.1    Greenland, K.J.2    Shinkel, T.A.3    Sernia, C.4
  • 163
    • 33748163574 scopus 로고    scopus 로고
    • The vasopressin system: physiology and clinical strategies
    • quiz 639-540
    • Treschan T.A., and Peters J. The vasopressin system: physiology and clinical strategies. Anesthesiology 105 (2006) 599-612 quiz 639-540
    • (2006) Anesthesiology , vol.105 , pp. 599-612
    • Treschan, T.A.1    Peters, J.2
  • 164
    • 0026597236 scopus 로고
    • The effect of chronic bilateral nephrectomy on plasma and brain angiotensin
    • Trolliet M.R., and Phillips M.I. The effect of chronic bilateral nephrectomy on plasma and brain angiotensin. J Hypertens 10 (1992) 29-36
    • (1992) J Hypertens , vol.10 , pp. 29-36
    • Trolliet, M.R.1    Phillips, M.I.2
  • 165
    • 0025912598 scopus 로고
    • Characterization and development of angiotensin II receptor subtypes (AT1 and AT2) in rat brain
    • Tsutsumi K., and Saavedra J.M. Characterization and development of angiotensin II receptor subtypes (AT1 and AT2) in rat brain. Am J Physiol 261 (1991) R209-216
    • (1991) Am J Physiol , vol.261
    • Tsutsumi, K.1    Saavedra, J.M.2
  • 166
    • 0032510977 scopus 로고    scopus 로고
    • p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy
    • Ushio-Fukai M., Alexander R.W., Akers M., and Griendling K.K. p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy. J Biol Chem 273 (1998) 15022-15029
    • (1998) J Biol Chem , vol.273 , pp. 15022-15029
    • Ushio-Fukai, M.1    Alexander, R.W.2    Akers, M.3    Griendling, K.K.4
  • 167
    • 0033529675 scopus 로고    scopus 로고
    • Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells
    • Ushio-Fukai M., Alexander R.W., Akers M., Yin Q., Fujio Y., Walsh K., et al. Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells. J Biol Chem 274 (1999) 22699-22704
    • (1999) J Biol Chem , vol.274 , pp. 22699-22704
    • Ushio-Fukai, M.1    Alexander, R.W.2    Akers, M.3    Yin, Q.4    Fujio, Y.5    Walsh, K.6
  • 168
    • 0032584723 scopus 로고    scopus 로고
    • Temporal dispersion of activation of phospholipase C-beta1 and -gamma isoforms by angiotensin II in vascular smooth muscle cells. Role of alphaq/11, alpha12, and beta gamma G protein subunits
    • Ushio-Fukai M., Griendling K.K., Akers M., Lyons P.R., and Alexander R.W. Temporal dispersion of activation of phospholipase C-beta1 and -gamma isoforms by angiotensin II in vascular smooth muscle cells. Role of alphaq/11, alpha12, and beta gamma G protein subunits. J Biol Chem 273 (1998) 19772-19777
    • (1998) J Biol Chem , vol.273 , pp. 19772-19777
    • Ushio-Fukai, M.1    Griendling, K.K.2    Akers, M.3    Lyons, P.R.4    Alexander, R.W.5
  • 169
    • 0033604577 scopus 로고    scopus 로고
    • Signaling by distinct classes of phosphoinositide 3-kinases
    • Vanhaesebroeck B., and Waterfield M.D. Signaling by distinct classes of phosphoinositide 3-kinases. Exp Cell Res 253 (1999) 239-254
    • (1999) Exp Cell Res , vol.253 , pp. 239-254
    • Vanhaesebroeck, B.1    Waterfield, M.D.2
  • 171
    • 0038606899 scopus 로고    scopus 로고
    • Brain renin-angiotensin system dysfunction in hypertension: recent advances and perspectives
    • Veerasingham S.J., and Raizada M.K. Brain renin-angiotensin system dysfunction in hypertension: recent advances and perspectives. Br J Pharmacol 139 (2003) 191-202
    • (2003) Br J Pharmacol , vol.139 , pp. 191-202
    • Veerasingham, S.J.1    Raizada, M.K.2
  • 172
    • 0026968949 scopus 로고
    • Involvement of adrenergic and angiotensinergic receptors in the paraventricular nucleus in the angiotensin II-induced vasopressin release
    • Veltmar A., Culman J., Qadri F., Rascher W., and Unger T. Involvement of adrenergic and angiotensinergic receptors in the paraventricular nucleus in the angiotensin II-induced vasopressin release. J Pharmacol Exp Ther 263 (1992) 1253-1260
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 1253-1260
    • Veltmar, A.1    Culman, J.2    Qadri, F.3    Rascher, W.4    Unger, T.5
  • 173
    • 0029858320 scopus 로고    scopus 로고
    • Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver
    • Veniant M., Menard J., Bruneval P., Morley S., Gonzales M.F., and Mullins J. Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver. J Clin Invest 98 (1996) 1966-1970
    • (1996) J Clin Invest , vol.98 , pp. 1966-1970
    • Veniant, M.1    Menard, J.2    Bruneval, P.3    Morley, S.4    Gonzales, M.F.5    Mullins, J.6
  • 174
    • 4344662040 scopus 로고    scopus 로고
    • PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane
    • Viard P., Butcher A.J., Halet G., Davies A., Nurnberg B., Heblich F., et al. PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane. Nat Neurosci 7 (2004) 939-946
    • (2004) Nat Neurosci , vol.7 , pp. 939-946
    • Viard, P.1    Butcher, A.J.2    Halet, G.3    Davies, A.4    Nurnberg, B.5    Heblich, F.6
  • 175
    • 0033113636 scopus 로고    scopus 로고
    • Gbetagamma dimers stimulate vascular L-type Ca2+ channels via phosphoinositide 3-kinase
    • Viard P., Exner T., Maier U., Mironneau J., Nurnberg B., and Macrez N. Gbetagamma dimers stimulate vascular L-type Ca2+ channels via phosphoinositide 3-kinase. Faseb J 13 (1999) 685-694
    • (1999) Faseb J , vol.13 , pp. 685-694
    • Viard, P.1    Exner, T.2    Maier, U.3    Mironneau, J.4    Nurnberg, B.5    Macrez, N.6
  • 176
    • 0036085084 scopus 로고    scopus 로고
    • Forebrain renin-angiotensin system has a tonic excitatory influence on renal sympathetic nerve activity
    • Wei S.G., and Felder R.B. Forebrain renin-angiotensin system has a tonic excitatory influence on renal sympathetic nerve activity. Am J Physiol Heart Circ Physiol 282 (2002) H890-895
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Wei, S.G.1    Felder, R.B.2
  • 177
    • 0019968821 scopus 로고
    • Angiotensin-like immunoreactivity in the brain of the spontaneously hypertensive rat
    • Weyhenmeyer J.A., and Phillips M.I. Angiotensin-like immunoreactivity in the brain of the spontaneously hypertensive rat. Hypertension 4 (1982) 514-523
    • (1982) Hypertension , vol.4 , pp. 514-523
    • Weyhenmeyer, J.A.1    Phillips, M.I.2
  • 178
    • 34047193877 scopus 로고    scopus 로고
    • Overexpression of angiotensin-converting enzyme 2 in the rostral
    • Yamazato M., Yamazato Y., Sun C., Diez-Freire C., and Raizada M.K. Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats. Hypertension 49 (2007) 926-931
    • (2007) Hypertension , vol.49 , pp. 926-931
    • Yamazato, M.1    Yamazato, Y.2    Sun, C.3    Diez-Freire, C.4    Raizada, M.K.5
  • 179
    • 0033119104 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3-kinase in angiotensin II regulation of norepinephrine neuromodulation in brain neurons of the spontaneously hypertensive rat
    • Yang H., and Raizada M.K. Role of phosphatidylinositol 3-kinase in angiotensin II regulation of norepinephrine neuromodulation in brain neurons of the spontaneously hypertensive rat. J Neurosci 19 (1999) 2413-2423
    • (1999) J Neurosci , vol.19 , pp. 2413-2423
    • Yang, H.1    Raizada, M.K.2
  • 180
    • 0029897648 scopus 로고    scopus 로고
    • Regulation of neuromodulatory actions of angiotensin II in the brain neurons by the Ras-dependent mitogen-activated protein kinase pathway
    • Yang H., Lu D., Yu K., and Raizada M.K. Regulation of neuromodulatory actions of angiotensin II in the brain neurons by the Ras-dependent mitogen-activated protein kinase pathway. J Neurosci 16 (1996) 4047-4058
    • (1996) J Neurosci , vol.16 , pp. 4047-4058
    • Yang, H.1    Lu, D.2    Yu, K.3    Raizada, M.K.4
  • 181
    • 0036337383 scopus 로고    scopus 로고
    • ANG II stimulation of neuritogenesis involves protein kinase B in brain neurons
    • Yang H., Shaw G., and Raizada M.K. ANG II stimulation of neuritogenesis involves protein kinase B in brain neurons. Am J Physiol Regul Integr Comp Physiol 283 (2002) R107-114
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.283
    • Yang, H.1    Shaw, G.2    Raizada, M.K.3
  • 182
    • 0034919743 scopus 로고    scopus 로고
    • Characterization of signal transduction pathway in neurotropic action of angiotensin II in brain neurons
    • Yang H., Wang X., and Raizada M.K. Characterization of signal transduction pathway in neurotropic action of angiotensin II in brain neurons. Endocrinology 142 (2001) 3502-3511
    • (2001) Endocrinology , vol.142 , pp. 3502-3511
    • Yang, H.1    Wang, X.2    Raizada, M.K.3
  • 183
    • 0025852111 scopus 로고
    • Brain and liver angiotensinogen messenger RNA in genetic hypertensive and normotensive rats
    • Yongue B.G., Angulo J.A., McEwen B.S., and Myers M.M. Brain and liver angiotensinogen messenger RNA in genetic hypertensive and normotensive rats. Hypertension 17 (1991) 485-491
    • (1991) Hypertension , vol.17 , pp. 485-491
    • Yongue, B.G.1    Angulo, J.A.2    McEwen, B.S.3    Myers, M.M.4
  • 184
    • 0029969927 scopus 로고    scopus 로고
    • Angiotensin II regulation of plasminogen activator inhibitor-1 gene expression in neurons of normotensive and spontaneously hypertensive rat brains
    • Yu K., Lu D., Paddy M.R., Lenk S.E., and Raizada M.K. Angiotensin II regulation of plasminogen activator inhibitor-1 gene expression in neurons of normotensive and spontaneously hypertensive rat brains. Endocrinology 137 (1996) 2503-2513
    • (1996) Endocrinology , vol.137 , pp. 2503-2513
    • Yu, K.1    Lu, D.2    Paddy, M.R.3    Lenk, S.E.4    Raizada, M.K.5
  • 185
    • 0035160293 scopus 로고    scopus 로고
    • Effect of renin-angiotensin system blockade on the expression of the angiotensinogen gene and induction of hypertrophy in rat kidney proximal tubular cells
    • Zhang S.L., To C., Chen X., Filep J.G., Tang S.S., Ingelfinger J.R., et al. Effect of renin-angiotensin system blockade on the expression of the angiotensinogen gene and induction of hypertrophy in rat kidney proximal tubular cells. Exp Nephrol 9 (2001) 109-117
    • (2001) Exp Nephrol , vol.9 , pp. 109-117
    • Zhang, S.L.1    To, C.2    Chen, X.3    Filep, J.G.4    Tang, S.S.5    Ingelfinger, J.R.6
  • 186
    • 0031227711 scopus 로고    scopus 로고
    • Modulation of K+ and Ca2+ currents in cultured neurons by an angiotensin II type 1a receptor peptide
    • Zhu M., Neubig R.R., Wade S.M., Posner P., Gelband C.H., Sumners C., et al. Modulation of K+ and Ca2+ currents in cultured neurons by an angiotensin II type 1a receptor peptide. Am J Physiol 273 (1997) C1040-1048
    • (1997) Am J Physiol , vol.273
    • Zhu, M.1    Neubig, R.R.2    Wade, S.M.3    Posner, P.4    Gelband, C.H.5    Sumners, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.