Angiotensin II-induced vascular smooth muscle cell migration and growth are mediated by cytochrome p450 1b1-dependent superoxide generation

Hypertension

Volumn 55, Issue 6, 2010, Pages 1461-1467

  Yaghini, Fariborz A ^a   Song, Chi Young ^a   Lavrentyev, Eduard N ^a   Ghafoor, Hafiz U B ^a   Fang, Xiao R ^a   Estes, Anne M ^a   Campbell, William B ^b   Malik, Kafait U ^a  

^a UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Angiotensin II; CYP1B1; ROS; Vascular smooth muscle cell growth

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; 15 HYDROXYICOSATETRAENOIC ACID; 2,4,3',5' TETRAMETHOXYSTILBENE; 20 HYDROXYICOSATETRAENOIC ACID; 5 HYDROXYICOSATETRAENOIC ACID; ADENOVIRUS VECTOR; ANGIOTENSIN II; ARACHIDONIC ACID; CYTOCHROME P450 1B1; CYTOCHROME P450 INHIBITOR; CYTOSOLIC PHOSPHOLIPASE A2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; SUPEROXIDE; TEMPOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FATTY ACID METABOLISM; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; VIRAL GENE DELIVERY SYSTEM; WOUND HEALING;

ANGIOTENSIN II; ANIMALS; AORTA; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CYTOCHROME P-450 CYP2B1; DNA; MUSCLE, SMOOTH, VASCULAR; PROTEINS; RATS; REACTIVE OXYGEN SPECIES; RENIN-ANGIOTENSIN SYSTEM; SENSITIVITY AND SPECIFICITY; SUPEROXIDES;

EID: 77953124375     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.110.150029     Document Type: Article

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