Effect of ingestion of dark chocolates with similar lipid composition and different cocoa content on antioxidant and lipid status in healthy humans

Food Chemistry

Volumn 132, Issue 3, 2012, Pages 1305-1310

  Lettieri Barbato, Daniele ^a   Villaño, Debora ^a   Beheydt, Bram ^b   Guadagni, Fiorella ^a   Trogh, Isabel ^b   Serafini, Mauro ^c  

^a IRCCS SAN RAFFAELE PISANA   (Italy)

^b Puratos Group Industrialaan 25   (Belgium)

^c ISTITUTO NAZIONALE DELLA NUTRIZIONE   (Italy)

Author keywords

Dark chocolate; Thiols; Total Antioxidant Capacity; Triacylglycerols

Indexed keywords

GLYCEROL;

ANTIOXIDANT CAPACITY; ANTIOXIDANT CONTENTS; ANTIOXIDANT STATUS; DARK CHOCOLATE; THIOLS; TOTAL ANTIOXIDANT CAPACITIES (TAC); TOTAL ANTIOXIDANT CAPACITY; TRIACYLGLYCEROLS;

ANTIOXIDANTS;

ANTIOXIDANT; ISOPROSTANE; LIPID; THIOL; TRIACYLGLYCEROL;

ARTICLE; CACAO; DARK CHOCOLATE; FOOD INTAKE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIPID COMPOSITION; NORMAL HUMAN; RANDOMIZATION; URINARY EXCRETION;

THEOBROMA CACAO;

EID: 84856231788     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2011.11.109     Document Type: Article

References (39)

1. S. Baba, M. Natsume, A. Yasuda, Y. Nakamura, T. Tamura, and N. Osakabe Plasma LDL and HDL cholesterol and oxidized LDL concentrations are altered in normo and hypercholesterolemic humans after intake of different levels of cocoa powder Journal of Nutrition 137 2007 1436 1441
2. S. Basu, and J. Helmersson Factors regulating isoprostane formation in vivo Antioxidants & Redox Signaling 7 2005 221 235
3. I.F.F. Benzie, and J.J. Strain The ferric reducing ability of plasma (FRAP) as a measurement of antioxidant power: the FRAP assay Analytical Biochemistry 239 1996 70 76
4. G.C. Burdge, and P.C. Calder Plasma cytokine response during the postprandial period: a potential causal process in vascular disease? British Journal of Nutrition 93 2005 3 9
5. S.A. Dillon, G.M. Lowe, D. Billington, and K. Rahman Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin-F(2 alpha) in smoking and nonsmoking men and women Journal of Nutrition 132 2002 168 171
6. E.L. Ding, S.M. Hutfless, X. Ding, and S. Girotra Chocolate and prevention of cardiovascular disease: a systematic review Nutrition & Metabolism 3 2006 2
7. G.L. Ellman Tissue sulfhydryl groups Archives of Biochemistry & Biophysics 82 1959 70 77
8. M.B. Engler, M.M. Engler, C.Y. Chen, M.J. Malloy, M.J. Malloy, and A. Browne Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults Journal of the American College of Nutrition 23 2004 197 204
9. A.J. Flammer, F. Hermann, I. Sudano, L. Spieker, M. Hermann, and K.A. Cooper Dark chocolate improves coronary vasomotion and reduces platelet reactivity Circulation 116 2007 2376 2382
10. P.M. Kris-Etherton, J.A. Derr, V.A. Mustad, F.H. Seligson, and T.A. Pearson Effects of a milk-chocolate bar per day substituted for a high-carbohydrate snack in young men on an NCEP/AHA Step 1 Diet American Journal of Clinical Nutrition 60 1994 1037S 1042S
11. S.C. Langley-Evans Consumption of black tea elicits an increase in plasma antioxidant potential in humans International Journal of Food Science and Nutrition 51 2000 309 315
12. R. Leenen, A.J. Roodenburg, L.B. Tijburg, and S.A. Wiseman A single dose of tea with or without milk increases plasma antioxidant activity in humans European Journal of Clinical Nutrition 54 2000 87 92
13. R.H. Liu Potential synergy of phytochemicals in cancer prevention: mechanism of action Journal of Nutrition 134 2004 3479S 3485S
14. M. Lorenz, N. Jochmann, A. von Krosigk, P. Martus, G. Baumann, and K. Stangl Addition of milk prevents vascular protective effects of tea European Heart Journal 28 2007 219 233
15. S. Lotito, and B. Frei Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: Cause, consequence, or epiphenomenon? Free Radical Biology & Medicine 41 2006 1727 1746
16. G. Maiani, G. Pappalardo, A. Ferro-Luzzi, A. Raguzzini, E. Azzini, and A. Guadalaxara Accumulation of beta-carotene in normal colorectal mucosa and colonic neoplasic lesions in humans Nutrition & Cancer 24 1995 23 31
17. C. Manach, G. Williamson, C. Morand, A. Scalbert, and C. Rémésy Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies American Journal of Clinical Nutrition 81 2005 230S 242S
18. S. Mathur, S. Devaraj, S.M. Grundy, and I. Jialal Cocoa products decrease low density lipoprotein oxidative susceptibility but do not affect biomarkers of inflammation in humans Journal of Nutrition 132 2002 3663 3667
19. K.J. Murphy, A.K. Chronopoulos, I. Singh, M.A. Francis, M.A. Francis, and H. Moriarty Dietary flavanols and procyanidin oligomers from cocoa (Theobroma cacao) inhibit platelet function American Journal of Clinical Nutrition 77 2003 1466 1473
20. J. Mursu, S. Voutilainen, T. Nurmi, T.H. Rissanen, J.K. Virtanen, and J. Kaikkonen Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans Free Radical Biology & Medicine 37 2004 1351 1359
21. N. Osakabe, S. Baba, A. Yasuda, T. Iwamoto, T. Iwamoto, and M. Kamiyama Daily cocoa intake reduces the susceptibility of low-density lipoprotein to oxidation as demonstrated in healthy volunteer Free Radical Research 34 2001 93 99
22. N. Pellegrini, M. Serafini, B. Colombi, D. Del Rio, S. Salvatore, and M. Bianchi Total Antioxidant Capacity of plant foods, beverages and oils consumed in Italy assessed by three different in vitro assays Journal of Nutrition 133 2003 2812 2819
23. N. Pellegrini, M. Serafini, S. Salvatore, D. Del Rio, M. Bianchi, and F. Brighenti Total antioxidant capacity of spices, dried fruits, nuts, pulses, cereals and sweets consumed in Italy assessed by three different in vitro assays Molecular Nutrition & Food Research 50 2006 1030 1038
24. C. Razquin, J.A. Martinez, M.A. Martinez-Gonzalez, M.T. Mitjavila, R. Estruch, and A. Marti A 3 years follow-up of a Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain European Journal of Clinical Nutrition 63 2009 1387 1393
25. V.C. Reddy, G.V. VidyaSagar, D. Sreeramulu, L. Venu, and M. Raghunath Addition of milk does not alter the antioxidant activity of black tea Annals of Nutrition & Metabolism 49 2005 189 195
26. D. Rein, S. Lotito, R.R. Holt, C.L. Keen, H.H. Schmitz, and C.G. Fraga Epicatechin in human plasma: in vivo determination and effect of chocolate consumption on plasma oxidation status Journal of Nutrition 130 2000 2109S 2114S
27. L.Y. Rios, M.-P. Gonthier, C. Rémésy, I. Mila, Lapierre.C. Lazarus, and S.A. Williamson Chocolate intake increases urinary excretion of polyphenol-derived phenolic acids in healthy human subjects American Journal of Clinical Nutrition 77 2003 912 918
28. H. Schroeter, C. Heiss, J. Balzer, P. Kleinbongard, C.L. Keen, and N.K. Hollenberg (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans Proceeding of the National Academy of Sciences U SA 103 2006 1024 1029
29. H. Schroeter, R.R. Holt, T.J. Orozco, H.H. Schmitz, and C.L. Keen Milk and absorption of dietary flavanoids Nature 426 2003 787 788
30. M. Serafini Back to the origin of the "antioxidant hypothesis": the lost role of the antioxidant network in disease prevention Journal of the Science of the Food & Agriculture 86 2006 1989 1991
31. M. Serafini, R. Bugianesi, G. Maiani, S. Valtuena, S. De Santis, and A. Crozier Plasma antioxidants from chocolate Nature 424 2003 1013
32. M. Serafini, R. Bugianesi, M. Salucci, E. Azzini, A. Raguzzini, and G. Maiani Effect of acute ingestion of fresh and stored lettuce (Lactucasativa) on plasma total antioxidant capacity and antioxidant levels in human subjects British Journal of Nutrition 88 2002 615 623
33. M. Serafini, and D. Del Río Understanding the association between dietary antioxidants, redox status and disease: is the Total Antioxidant Capacity the right tool? Redox Report 9 2004 145 152
34. M. Serafini, A. Ghiselli, and A. Ferro-Luzzi In vivo antioxidant effect of green and black tea in man European Journal of Clinical Nutrition 50 1996 28 32
35. D. Taubert, R. Roesen, C. Lehmann, N. Jung, and E. Schömig Effects of low habitual cocoa intake on blood pressure and bioactive nitric oxide: a randomized controlled trial Journal of the American Medical Association 298 2007 49 60
36. W.-C. Tsai, Y.H. Li, C.C. Lin, T.H. Chao, and J.H. Chen Effects of oxidative stress on endothelial function after a high-fat meal Clinical Science 106 2004 315 319
37. P.M. Ueland, M.A. Mansoor, A.B. Guttormsen, F. Muller, P. Aukrust, and H. Refsum Reduced, oxidized and protein-bound forms of homocysteine and other aminothiols in plasma comprise the redox thiol status - a possible element of the extracellular antioxidant defense system Journal of Nutrition 126 1996 1281S 1284S
38. M. Valko, D. Leibfritz, J. Moncol, M.T. Cronin, M. Mazur, and J. Telser Free radicals and antioxidants in normal physiological functions and human disease International Journal of Biochemistry and Cellular Biology 39 2007 44 84
39. J.F. Wang, D.D. Schramm, R.R. Holt, J.L. Ensunsa, C.G. Fraga, and H.H. Schmitz A dose-response effect from chocolate consumption on plasma epicatechin and oxidative damage Journal of Nutrition 130 2000 2115S 2119S