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Volumn 228, Issue 2, 2012, Pages 261-271

LMN diet, rich in polyphenols and polyunsaturated fatty acids, improves mouse cognitive decline associated with aging and Alzheimer's disease

Author keywords

Aging; Alzheimer's disease; Memory and learning; Polyphenols; Polyunsaturated fatty acids

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; POLYPHENOL; POLYUNSATURATED FATTY ACID;

EID: 84856215978     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2011.11.014     Document Type: Article
Times cited : (50)

References (70)
  • 1
    • 80054039196 scopus 로고    scopus 로고
    • Terminal decline and practice effects in older adults without dementia: the MoVIES project
    • Dodge H.H., Wang C.N., Chang C.C., Ganguli M. Terminal decline and practice effects in older adults without dementia: the MoVIES project. Neurology 2011, 77:722-730.
    • (2011) Neurology , vol.77 , pp. 722-730
    • Dodge, H.H.1    Wang, C.N.2    Chang, C.C.3    Ganguli, M.4
  • 2
    • 80052410357 scopus 로고    scopus 로고
    • The ageing systemic milieu negatively regulates neurogenesis and cognitive function
    • Villeda S.A., Luo J., Mosher K.I., Zou B., Britschgi M., Bieri G., et al. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature 2011, 477:90-94.
    • (2011) Nature , vol.477 , pp. 90-94
    • Villeda, S.A.1    Luo, J.2    Mosher, K.I.3    Zou, B.4    Britschgi, M.5    Bieri, G.6
  • 3
    • 0036751978 scopus 로고    scopus 로고
    • A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes
    • Esposito E., Rotilio D., Di Matteo V., Di Giulio C., Cacchio M., Algeri S. A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes. Neurobiol Aging 2002, 23:719-735.
    • (2002) Neurobiol Aging , vol.23 , pp. 719-735
    • Esposito, E.1    Rotilio, D.2    Di Matteo, V.3    Di Giulio, C.4    Cacchio, M.5    Algeri, S.6
  • 4
    • 77952475396 scopus 로고    scopus 로고
    • Dietary polyphenols, inflammation, and cancer
    • Guo W., Kong E., Meydani M. Dietary polyphenols, inflammation, and cancer. Nutr Cancer 2009, 61:807-810.
    • (2009) Nutr Cancer , vol.61 , pp. 807-810
    • Guo, W.1    Kong, E.2    Meydani, M.3
  • 5
    • 74949084835 scopus 로고    scopus 로고
    • Wine and oxidative stress: up-to-date evidence of the effects of moderate wine consumption on oxidative damage in humans
    • Covas M.I., Gambert P., Fito M., de la T.R. Wine and oxidative stress: up-to-date evidence of the effects of moderate wine consumption on oxidative damage in humans. Atherosclerosis 2010, 208:297-304.
    • (2010) Atherosclerosis , vol.208 , pp. 297-304
    • Covas, M.I.1    Gambert, P.2    Fito, M.3    de la, T.R.4
  • 6
    • 33646116675 scopus 로고    scopus 로고
    • Intervention of antioxidant system function of aged rats by giving fruit juices with different antioxidant capacities
    • Xu J., Guo C.J., Yang J.J., Wei J.Y., Li Y.F., Pang W., et al. Intervention of antioxidant system function of aged rats by giving fruit juices with different antioxidant capacities. Zhonghua Yu Fang Yi Xue Za Zhi 2005, 39:80-83.
    • (2005) Zhonghua Yu Fang Yi Xue Za Zhi , vol.39 , pp. 80-83
    • Xu, J.1    Guo, C.J.2    Yang, J.J.3    Wei, J.Y.4    Li, Y.F.5    Pang, W.6
  • 7
    • 42249103252 scopus 로고    scopus 로고
    • Fatty acids, lipid metabolism and Alzheimer pathology
    • Hooijmans C.R., Kiliaan A.J. Fatty acids, lipid metabolism and Alzheimer pathology. Eur J Pharmacol 2008, 585:176-196.
    • (2008) Eur J Pharmacol , vol.585 , pp. 176-196
    • Hooijmans, C.R.1    Kiliaan, A.J.2
  • 8
    • 0036334166 scopus 로고    scopus 로고
    • Caloric intake and the risk of Alzheimer disease
    • Luchsinger J.A., Tang M.X., Shea S., Mayeux R. Caloric intake and the risk of Alzheimer disease. Arch Neurol 2002, 59:1258-1263.
    • (2002) Arch Neurol , vol.59 , pp. 1258-1263
    • Luchsinger, J.A.1    Tang, M.X.2    Shea, S.3    Mayeux, R.4
  • 9
  • 11
    • 26244450690 scopus 로고    scopus 로고
    • Oxidative stress and inflammation in brain aging: nutritional considerations
    • Joseph J.A., Shukitt-Hale B., Casadesus G., Fisher D. Oxidative stress and inflammation in brain aging: nutritional considerations. Neurochem Res 2005, 30:927-935.
    • (2005) Neurochem Res , vol.30 , pp. 927-935
    • Joseph, J.A.1    Shukitt-Hale, B.2    Casadesus, G.3    Fisher, D.4
  • 12
    • 33747286388 scopus 로고    scopus 로고
    • Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets
    • Ramassamy C. Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets. Eur J Pharmacol 2006, 545:51-64.
    • (2006) Eur J Pharmacol , vol.545 , pp. 51-64
    • Ramassamy, C.1
  • 13
    • 80054862809 scopus 로고    scopus 로고
    • Grape seed proanthocyanidin lowers brain oxidative stress in adult and middle-aged rats
    • Asha D.S., Sagar Chandrasekar B.K., Manjula K.R., Ishii N. Grape seed proanthocyanidin lowers brain oxidative stress in adult and middle-aged rats. Exp Gerontol 2011, 46:958-964.
    • (2011) Exp Gerontol , vol.46 , pp. 958-964
    • Asha, D.S.1    Sagar Chandrasekar, B.K.2    Manjula, K.R.3    Ishii, N.4
  • 14
    • 74949113952 scopus 로고    scopus 로고
    • A diet enriched in polyphenols and polyunsaturated fatty acids, LMN diet, induces neurogenesis in the subventricular zone and hippocampus of adult mouse brain
    • Valente T., Hidalgo J., Bolea I., Ramirez B., Anglés N., Reguant J., et al. A diet enriched in polyphenols and polyunsaturated fatty acids, LMN diet, induces neurogenesis in the subventricular zone and hippocampus of adult mouse brain. J Alzheimer's Dis 2009, 18:849-865.
    • (2009) J Alzheimer's Dis , vol.18 , pp. 849-865
    • Valente, T.1    Hidalgo, J.2    Bolea, I.3    Ramirez, B.4    Anglés, N.5    Reguant, J.6
  • 15
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
    • Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., et al. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 1996, 274:99-102.
    • (1996) Science , vol.274 , pp. 99-102
    • Hsiao, K.1    Chapman, P.2    Nilsen, S.3    Eckman, C.4    Harigaya, Y.5    Younkin, S.6
  • 16
    • 0026580496 scopus 로고
    • Age-related changes in spontaneous behavior and learning in NMRI mice from middle to old age
    • Lamberty Y., Gower A.J. Age-related changes in spontaneous behavior and learning in NMRI mice from middle to old age. Physiol Behav 1992, 51:81-88.
    • (1992) Physiol Behav , vol.51 , pp. 81-88
    • Lamberty, Y.1    Gower, A.J.2
  • 17
    • 0016818575 scopus 로고
    • Validity of head-dipping as a measure of exploration in a modified hole-board
    • File S.E., Wardill A.G. Validity of head-dipping as a measure of exploration in a modified hole-board. Psychopharmacologia 1975, 44:53-59.
    • (1975) Psychopharmacologia , vol.44 , pp. 53-59
    • File, S.E.1    Wardill, A.G.2
  • 18
    • 0023255981 scopus 로고
    • The use of a plus-maze to measure anxiety in the mouse
    • Lister R.G. The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology (Berl) 1987, 92:180-185.
    • (1987) Psychopharmacology (Berl) , vol.92 , pp. 180-185
    • Lister, R.G.1
  • 19
    • 67349121299 scopus 로고    scopus 로고
    • High-fat diet induced adiposity and insulin resistance in mice lacking the myotonic dystrophy protein kinase
    • Llagostera E., Carmona M.C., Vicente M., Escorihuela R.M., Kaliman P. High-fat diet induced adiposity and insulin resistance in mice lacking the myotonic dystrophy protein kinase. FEBS Lett 2009, 583:2121-2125.
    • (2009) FEBS Lett , vol.583 , pp. 2121-2125
    • Llagostera, E.1    Carmona, M.C.2    Vicente, M.3    Escorihuela, R.M.4    Kaliman, P.5
  • 20
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rat
    • Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods 1984, 11:47-60.
    • (1984) J Neurosci Methods , vol.11 , pp. 47-60
    • Morris, R.1
  • 21
    • 78649504377 scopus 로고    scopus 로고
    • Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease
    • Parachikova A., Green K.N., Hendrix C., LaFerla F.M. Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease. PLoS One 2010, 5:e14015.
    • (2010) PLoS One , vol.5
    • Parachikova, A.1    Green, K.N.2    Hendrix, C.3    LaFerla, F.M.4
  • 22
    • 9844255568 scopus 로고    scopus 로고
    • Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice
    • Carlson G.A., Borchelt D.R., Dake A., Turner S., Danielson V., Coffin J.D., et al. Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice. Hum Mol Genet 1997, 6:1951-1959.
    • (1997) Hum Mol Genet , vol.6 , pp. 1951-1959
    • Carlson, G.A.1    Borchelt, D.R.2    Dake, A.3    Turner, S.4    Danielson, V.5    Coffin, J.D.6
  • 24
    • 77950219236 scopus 로고    scopus 로고
    • Increased food intake leads to obesity and insulin resistance in the tg2576 Alzheimer's disease mouse model
    • Kohjima M., Sun Y., Chan L. Increased food intake leads to obesity and insulin resistance in the tg2576 Alzheimer's disease mouse model. Endocrinology 2010, 151:1532-1540.
    • (2010) Endocrinology , vol.151 , pp. 1532-1540
    • Kohjima, M.1    Sun, Y.2    Chan, L.3
  • 25
    • 0037204597 scopus 로고    scopus 로고
    • Dynamics of cell proliferation in the adult dentate gyrus of two inbred strains of mice
    • Hayes N.L., Nowakowski R.S. Dynamics of cell proliferation in the adult dentate gyrus of two inbred strains of mice. Brain Res Dev Brain Res 2002, 134:77-85.
    • (2002) Brain Res Dev Brain Res , vol.134 , pp. 77-85
    • Hayes, N.L.1    Nowakowski, R.S.2
  • 27
    • 74949133060 scopus 로고    scopus 로고
    • Early biochemical and morphological modifications in the brain of a transgenic mouse model of Alzheimer's disease: a role for peroxisomes
    • Cimini A., Moreno S., D'Amelio M., Cristiano L., D'Angelo B., Falone S., et al. Early biochemical and morphological modifications in the brain of a transgenic mouse model of Alzheimer's disease: a role for peroxisomes. J Alzheimer's Dis 2009, 18:935-952.
    • (2009) J Alzheimer's Dis , vol.18 , pp. 935-952
    • Cimini, A.1    Moreno, S.2    D'Amelio, M.3    Cristiano, L.4    D'Angelo, B.5    Falone, S.6
  • 28
    • 72549084916 scopus 로고    scopus 로고
    • Oxidation of potassium channels by ROS: a general mechanism of aging and neurodegeneration?
    • Sesti F., Liu S., Cai S.Q. Oxidation of potassium channels by ROS: a general mechanism of aging and neurodegeneration?. Trends Cell Biol 2010, 20:45-51.
    • (2010) Trends Cell Biol , vol.20 , pp. 45-51
    • Sesti, F.1    Liu, S.2    Cai, S.Q.3
  • 29
    • 67349255336 scopus 로고    scopus 로고
    • Oxidation of a potassium channel causes progressive sensory function loss during aging
    • Cai S.Q., Sesti F. Oxidation of a potassium channel causes progressive sensory function loss during aging. Nat Neurosci 2009, 12:611-617.
    • (2009) Nat Neurosci , vol.12 , pp. 611-617
    • Cai, S.Q.1    Sesti, F.2
  • 30
    • 70350482460 scopus 로고    scopus 로고
    • Nutrition, brain aging, and neurodegeneration
    • Joseph J., Cole G., Head E., Ingram D. Nutrition, brain aging, and neurodegeneration. J Neurosci 2009, 29:12795-12801.
    • (2009) J Neurosci , vol.29 , pp. 12795-12801
    • Joseph, J.1    Cole, G.2    Head, E.3    Ingram, D.4
  • 31
    • 13844272542 scopus 로고    scopus 로고
    • Reversing the deleterious effects of aging on neuronal communication and behavior: beneficial properties of fruit polyphenolic compounds
    • Joseph J.A., Shukitt-Hale B., Casadesus G. Reversing the deleterious effects of aging on neuronal communication and behavior: beneficial properties of fruit polyphenolic compounds. Am J Clin Nutr 2005, 81:313S-316S.
    • (2005) Am J Clin Nutr , vol.81
    • Joseph, J.A.1    Shukitt-Hale, B.2    Casadesus, G.3
  • 32
    • 1642268085 scopus 로고    scopus 로고
    • Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor alpha in mice
    • Inoue H., Jiang X.F., Katayama T., Osada S., Umesono K., Namura S. Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor alpha in mice. Neurosci Lett 2003, 352:203-206.
    • (2003) Neurosci Lett , vol.352 , pp. 203-206
    • Inoue, H.1    Jiang, X.F.2    Katayama, T.3    Osada, S.4    Umesono, K.5    Namura, S.6
  • 33
    • 0034477202 scopus 로고    scopus 로고
    • Longitudinal age-related changes in motor activities and spatial orientation in CD-1 mice
    • Joyal C.C., Beaudin S., Lalonde R. Longitudinal age-related changes in motor activities and spatial orientation in CD-1 mice. Arch Physiol Biochem 2000, 108:248-256.
    • (2000) Arch Physiol Biochem , vol.108 , pp. 248-256
    • Joyal, C.C.1    Beaudin, S.2    Lalonde, R.3
  • 34
    • 78249277425 scopus 로고    scopus 로고
    • The UPR and the anti-oxidant response: relevance to sleep and sleep loss
    • Brown M.K., Naidoo N. The UPR and the anti-oxidant response: relevance to sleep and sleep loss. Mol Neurobiol 2010, 42:103-113.
    • (2010) Mol Neurobiol , vol.42 , pp. 103-113
    • Brown, M.K.1    Naidoo, N.2
  • 35
    • 0037088956 scopus 로고    scopus 로고
    • Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months
    • King D.L., Arendash G.W. Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months. Physiol Behav 2002, 75:627-642.
    • (2002) Physiol Behav , vol.75 , pp. 627-642
    • King, D.L.1    Arendash, G.W.2
  • 36
    • 9644254315 scopus 로고    scopus 로고
    • Aspects of spatial memory and behavioral disinhibition in Tg2576 transgenic mice as a model of Alzheimer's disease
    • Ognibene E., Middei S., Daniele S., Adriani W., Ghirardi O., Caprioli A., et al. Aspects of spatial memory and behavioral disinhibition in Tg2576 transgenic mice as a model of Alzheimer's disease. Behav Brain Res 2005, 156:225-232.
    • (2005) Behav Brain Res , vol.156 , pp. 225-232
    • Ognibene, E.1    Middei, S.2    Daniele, S.3    Adriani, W.4    Ghirardi, O.5    Caprioli, A.6
  • 37
    • 34249733132 scopus 로고    scopus 로고
    • Increase of locomotor activity underlying the behavioral disinhibition in tg2576 mice
    • Gil-Bea F.J., Aisa B., Schliebs R., Ramirez M.J. Increase of locomotor activity underlying the behavioral disinhibition in tg2576 mice. Behav Neurosci 2007, 121:340-344.
    • (2007) Behav Neurosci , vol.121 , pp. 340-344
    • Gil-Bea, F.J.1    Aisa, B.2    Schliebs, R.3    Ramirez, M.J.4
  • 38
    • 0038022595 scopus 로고    scopus 로고
    • Transgenic mice expressing the betaAPP695SWE mutation: effects on exploratory activity, anxiety, and motor coordination
    • Lalonde R., Lewis T.L., Strazielle C., Kim H., Fukuchi K. Transgenic mice expressing the betaAPP695SWE mutation: effects on exploratory activity, anxiety, and motor coordination. Brain Res 2003, 977:38-45.
    • (2003) Brain Res , vol.977 , pp. 38-45
    • Lalonde, R.1    Lewis, T.L.2    Strazielle, C.3    Kim, H.4    Fukuchi, K.5
  • 39
    • 33745248632 scopus 로고    scopus 로고
    • Evaluation of white matter integrity in ex vivo brains of amyloid plaque-bearing APPsw transgenic mice using magnetic resonance diffusion tensor imaging
    • Harms M.P., Kotyk J.J., Merchant K.M. Evaluation of white matter integrity in ex vivo brains of amyloid plaque-bearing APPsw transgenic mice using magnetic resonance diffusion tensor imaging. Exp Neurol 2006, 199:408-415.
    • (2006) Exp Neurol , vol.199 , pp. 408-415
    • Harms, M.P.1    Kotyk, J.J.2    Merchant, K.M.3
  • 40
    • 0037088959 scopus 로고    scopus 로고
    • Intra- and intertask relationships in a behavioral test battery given to Tg2576 transgenic mice and controls
    • Arendash G.W., King D.L. Intra- and intertask relationships in a behavioral test battery given to Tg2576 transgenic mice and controls. Physiol Behav 2002, 75:643-652.
    • (2002) Physiol Behav , vol.75 , pp. 643-652
    • Arendash, G.W.1    King, D.L.2
  • 41
    • 0036743625 scopus 로고    scopus 로고
    • Overexpression of hAPPswe impairs rewarded alternation and contextual fear conditioning in a transgenic mouse model of Alzheimer's disease
    • Corcoran K.A., Lu Y., Turner R.S., Maren S. Overexpression of hAPPswe impairs rewarded alternation and contextual fear conditioning in a transgenic mouse model of Alzheimer's disease. Learn Mem 2002, 9:243-252.
    • (2002) Learn Mem , vol.9 , pp. 243-252
    • Corcoran, K.A.1    Lu, Y.2    Turner, R.S.3    Maren, S.4
  • 42
    • 34848893384 scopus 로고    scopus 로고
    • Longitudinal brain corticotropin releasing factor and somatostatin in a transgenic mouse (TG2576) model of Alzheimer's disease
    • Horgan J., Miguel-Hidalgo J.J., Thrasher M., Bissette G. Longitudinal brain corticotropin releasing factor and somatostatin in a transgenic mouse (TG2576) model of Alzheimer's disease. J Alzheimer's Dis 2007, 12:115-127.
    • (2007) J Alzheimer's Dis , vol.12 , pp. 115-127
    • Horgan, J.1    Miguel-Hidalgo, J.J.2    Thrasher, M.3    Bissette, G.4
  • 43
    • 77955267314 scopus 로고    scopus 로고
    • Cognitive impairment in old people living in the community
    • Paul C., Ribeiro O., Santos P. Cognitive impairment in old people living in the community. Arch Gerontol Geriatr 2010, 51:121-124.
    • (2010) Arch Gerontol Geriatr , vol.51 , pp. 121-124
    • Paul, C.1    Ribeiro, O.2    Santos, P.3
  • 44
    • 77957885945 scopus 로고    scopus 로고
    • Assessment of spatial memory in mice
    • Sharma S., Rakoczy S., Brown-Borg H. Assessment of spatial memory in mice. Life Sci 2010, 87:521-536.
    • (2010) Life Sci , vol.87 , pp. 521-536
    • Sharma, S.1    Rakoczy, S.2    Brown-Borg, H.3
  • 45
    • 0037736704 scopus 로고    scopus 로고
    • Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model
    • Joseph J.A., Denisova N.A., Arendash G., Gordon M., Diamond D., Shukitt-Hale B., et al. Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci 2003, 6:153-162.
    • (2003) Nutr Neurosci , vol.6 , pp. 153-162
    • Joseph, J.A.1    Denisova, N.A.2    Arendash, G.3    Gordon, M.4    Diamond, D.5    Shukitt-Hale, B.6
  • 46
    • 33750807197 scopus 로고    scopus 로고
    • Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease
    • Hartman R.E., Shah A., Fagan A.M., Schwetye K.E., Parsadanian M., Schulman R.N., et al. Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease. Neurobiol Dis 2006, 24:506-515.
    • (2006) Neurobiol Dis , vol.24 , pp. 506-515
    • Hartman, R.E.1    Shah, A.2    Fagan, A.M.3    Schwetye, K.E.4    Parsadanian, M.5    Schulman, R.N.6
  • 47
    • 0344826082 scopus 로고    scopus 로고
    • Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimer's disease by chronic Ginkgo biloba treatment
    • Stackman R.W., Eckenstein F., Frei B., Kulhanek D., Nowlin J., Quinn J.F. Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimer's disease by chronic Ginkgo biloba treatment. Exp Neurol 2003, 184:510-520.
    • (2003) Exp Neurol , vol.184 , pp. 510-520
    • Stackman, R.W.1    Eckenstein, F.2    Frei, B.3    Kulhanek, D.4    Nowlin, J.5    Quinn, J.F.6
  • 48
    • 65449188292 scopus 로고    scopus 로고
    • Exercise and the brain: something to chew on
    • van Praag H. Exercise and the brain: something to chew on. Trends Neurosci 2009, 32:283-290.
    • (2009) Trends Neurosci , vol.32 , pp. 283-290
    • van Praag, H.1
  • 49
    • 13844257284 scopus 로고    scopus 로고
    • Ischemia-induced neurogenesis is preserved but reduced in the aged rodent brain
    • Jin K., Minami M., Xie L., Sun Y., Mao X.O., Wang Y., et al. Ischemia-induced neurogenesis is preserved but reduced in the aged rodent brain. Aging Cell 2004, 3:373-377.
    • (2004) Aging Cell , vol.3 , pp. 373-377
    • Jin, K.1    Minami, M.2    Xie, L.3    Sun, Y.4    Mao, X.O.5    Wang, Y.6
  • 53
    • 36549023476 scopus 로고    scopus 로고
    • Neurogenic responses to amyloid-beta plaques in the brain of Alzheimer's disease-like transgenic (pPDGF-APPSw,Ind) mice
    • Gan L., Qiao S., Lan X., Chi L., Luo C., Lien L., et al. Neurogenic responses to amyloid-beta plaques in the brain of Alzheimer's disease-like transgenic (pPDGF-APPSw,Ind) mice. Neurobiol Dis 2008, 29:71-80.
    • (2008) Neurobiol Dis , vol.29 , pp. 71-80
    • Gan, L.1    Qiao, S.2    Lan, X.3    Chi, L.4    Luo, C.5    Lien, L.6
  • 54
    • 33751546646 scopus 로고    scopus 로고
    • Metallothionein-I and -III expression in animal models of Alzheimer disease
    • Carrasco J., Adlard P., Cotman C., Quintana A., Penkowa M., Xu F., et al. Metallothionein-I and -III expression in animal models of Alzheimer disease. Neuroscience 2006, 143:911-922.
    • (2006) Neuroscience , vol.143 , pp. 911-922
    • Carrasco, J.1    Adlard, P.2    Cotman, C.3    Quintana, A.4    Penkowa, M.5    Xu, F.6
  • 55
    • 0036644989 scopus 로고    scopus 로고
    • Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody
    • Chauhan N.B., Siegel G.J. Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody. J Neurosci Res 2002, 69:10-23.
    • (2002) J Neurosci Res , vol.69 , pp. 10-23
    • Chauhan, N.B.1    Siegel, G.J.2
  • 57
    • 34248181511 scopus 로고    scopus 로고
    • Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model
    • Roberson E.D., Scearce-Levie K., Palop J.J., Yan F., Cheng I.H., Wu T., et al. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science 2007, 316:750-754.
    • (2007) Science , vol.316 , pp. 750-754
    • Roberson, E.D.1    Scearce-Levie, K.2    Palop, J.J.3    Yan, F.4    Cheng, I.H.5    Wu, T.6
  • 59
    • 43649097836 scopus 로고    scopus 로고
    • Aged wild-type and APP, PS1, and APP+PS1 mice present similar deficits in associative learning and synaptic plasticity independent of amyloid load
    • Gruart A., Lopez-Ramos J.C., Munoz M.D., gado-Garcia J.M. Aged wild-type and APP, PS1, and APP+PS1 mice present similar deficits in associative learning and synaptic plasticity independent of amyloid load. Neurobiol Dis 2008, 30:439-450.
    • (2008) Neurobiol Dis , vol.30 , pp. 439-450
    • Gruart, A.1    Lopez-Ramos, J.C.2    Munoz, M.D.3    gado-Garcia, J.M.4
  • 60
    • 33645038471 scopus 로고    scopus 로고
    • A specific amyloid-beta protein assembly in the brain impairs memory
    • Lesne S., Koh M.T., Kotilinek L., Kayed R., Glabe C.G., Yang A., et al. A specific amyloid-beta protein assembly in the brain impairs memory. Nature 2006, 440:352-357.
    • (2006) Nature , vol.440 , pp. 352-357
    • Lesne, S.1    Koh, M.T.2    Kotilinek, L.3    Kayed, R.4    Glabe, C.G.5    Yang, A.6
  • 61
    • 0034643888 scopus 로고    scopus 로고
    • The molecular and genetic basis of AD: the end of the beginning: the 2000 Wartenberg lecture
    • Rosenberg R.N. The molecular and genetic basis of AD: the end of the beginning: the 2000 Wartenberg lecture. Neurology 2000, 54:2045-2054.
    • (2000) Neurology , vol.54 , pp. 2045-2054
    • Rosenberg, R.N.1
  • 64
    • 78650448026 scopus 로고    scopus 로고
    • Amyloid-beta peptides in plasma and cognitive decline after 1 year follow-up in Alzheimer's disease patients
    • Laske C., Sopova K., Gkotsis C., Eschweiler G.W., Straten G., Gawaz M., et al. Amyloid-beta peptides in plasma and cognitive decline after 1 year follow-up in Alzheimer's disease patients. J Alzheimer's Dis 2010, 21:1263-1269.
    • (2010) J Alzheimer's Dis , vol.21 , pp. 1263-1269
    • Laske, C.1    Sopova, K.2    Gkotsis, C.3    Eschweiler, G.W.4    Straten, G.5    Gawaz, M.6
  • 65
    • 0035863055 scopus 로고    scopus 로고
    • Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease
    • Kawarabayashi T., Younkin L.H., Saido T.C., Shoji M., Ashe K.H., Younkin S.G. Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J Neurosci 2001, 21:372-381.
    • (2001) J Neurosci , vol.21 , pp. 372-381
    • Kawarabayashi, T.1    Younkin, L.H.2    Saido, T.C.3    Shoji, M.4    Ashe, K.H.5    Younkin, S.G.6
  • 66
    • 0035918312 scopus 로고    scopus 로고
    • Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains
    • Kuo Y.M., Kokjohn T.A., Beach T.G., Sue L.I., Brune D., Lopez J.C. Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains. J Biol Chem 2001, 276:12991-12998.
    • (2001) J Biol Chem , vol.276 , pp. 12991-12998
    • Kuo, Y.M.1    Kokjohn, T.A.2    Beach, T.G.3    Sue, L.I.4    Brune, D.5    Lopez, J.C.6
  • 69
    • 54149084726 scopus 로고    scopus 로고
    • Effects of ginkgo biloba extract EGb761 on expression of RAGE and LRP-1 in cerebral microvascular endothelial cells under chronic hypoxia and hypoglycemia
    • Yan F.L., Zheng Y., Zhao F.D. Effects of ginkgo biloba extract EGb761 on expression of RAGE and LRP-1 in cerebral microvascular endothelial cells under chronic hypoxia and hypoglycemia. Acta Neuropathol 2008, 116:529-535.
    • (2008) Acta Neuropathol , vol.116 , pp. 529-535
    • Yan, F.L.1    Zheng, Y.2    Zhao, F.D.3
  • 70
    • 45549097081 scopus 로고    scopus 로고
    • Site-specific blockade of RAGE-Vd prevents amyloid-beta oligomer neurotoxicity
    • Sturchler E., Galichet A., Weibel M., Leclerc E., Heizmann C.W. Site-specific blockade of RAGE-Vd prevents amyloid-beta oligomer neurotoxicity. J Neurosci 2008, 28:5149-5158.
    • (2008) J Neurosci , vol.28 , pp. 5149-5158
    • Sturchler, E.1    Galichet, A.2    Weibel, M.3    Leclerc, E.4    Heizmann, C.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.