The GB Virus C (GBV-C) ns3 serine protease inhibits HIV-1 replication in a CD4+ t lymphocyte cell line without decreasing HIV receptor expression

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  George, Sarah L ^a,b   Varmaz, Dino ^a,b   Tavis, John E ^a   Chowdhury, Adnan ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAINT LOUIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; MONTIRELIN; SERINE PROTEINASE; VIRUS RECEPTOR; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; NS3 PROTEIN, FLAVIVIRUS; RNA HELICASE; VIRUS PROTEIN;

ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; HEPATITIS G VIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; VIRUS INHIBITION; VIRUS REPLICATION; WESTERN BLOTTING; AMINO ACID SEQUENCE; CELL LINE; DOWN REGULATION; DRUG EFFECT; ENZYMOLOGY; EVALUATION; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; LEUKEMIA CELL LINE; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; SEQUENCE HOMOLOGY; VIROLOGY; VIRUS GENOME;

GB VIRUS C; HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; DOWN-REGULATION; GB VIRUS C; GENE EXPRESSION; GENOME, VIRAL; HIV-1; HUMANS; JURKAT CELLS; MOLECULAR SEQUENCE DATA; RECEPTORS, HIV; RNA HELICASES; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; TRANSFECTION; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84856086641     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030653     Document Type: Article

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