Sequence and genomic organization of GBV-C: A novel member of the flaviviridae associated with human Non-A-E hepatitis

Journal of Medical Virology

Volumn 48, Issue 1, 1996, Pages 60-67

  Leary, Thomas P ^a   Muerhoff, A Scott ^a   Simons, John N ^a   Pilot Matias, Tami J ^a   Erker, James C ^a   Chalmers, Michelle L ^a   Schlauder, George G ^a   Dawson, George J ^a   Desai, Suresh M ^a   Mushahwar, Isa K ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

GB virus; HCV; RNA virus

Indexed keywords

ARTICLE; FLAVIVIRUS; GENETIC ANALYSIS; HEPATITIS; HEPATITIS GB VIRUS; HUMAN; NUCLEOTIDE SEQUENCE; RNA VIRUS; VIRUS CHARACTERIZATION; VIRUS GENOME;

AMINO ACID SEQUENCE; ENDOPEPTIDASES; FLAVIVIRIDAE; GENOME, VIRAL; HEPATITIS VIRUSES; HEPATITIS, VIRAL, HUMAN; HUMANS; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; VIRAL PROTEINS;

FLAVIVIRIDAE; FLAVIVIRUS; GB VIRUS C/HEPATITIS G VIRUS; HEPATITIS C VIRUS; NON-A, NON-B HEPATITIS VIRUS; RNA VIRUSES;

EID: 15844407954     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9071(199601)48:1<60::AID-JMV10>3.0.CO;2-A     Document Type: Article

References (29)

1. Alter MJ, Margolis HS, Krawczynski K, Judson FN, Mares A, Alexander WJ, Hu PY, Miller JK, Gerber MA, Sampliner RE, Meeks EL, Beach MJ (1992): The natural history of community acquired hepatitis C in the United States. New England Journal of Medicine 327:1899-1905.
2. Bartenschlager R, Ahlborn-Laake L, Yasargil K, Mous J, Jacobsen H (1995): Substrate determinants for cleavage in cis and in trans by the hepatitis C virus NS3 proteinase. Journal Virology 69:198-205.
3. Bukh J, Purcell RH, Miller RH (1993): At least 12 genotypes of hepatitis C virus predicted by sequence analysis of the putative E1 gene of isolates collected worldwide. Proceedings of the National Academy of Sciences USA 90:8234-8238.
4. Buti M, Jardi R, Rodriguez-Frias F, Quer J, Esteban R, Guardia J (1994): Etiology of acute sporadic hepatitis in Spain: The role of hepatitis C and E viruses. Journal of Hepatology 20:589-592.
5. Choo Q-L, Richman KH, Han JH, Berger K, Lee C, Dong C, Gallegos C, Coit D, Medina-Selby A, Barr PJ, Weiner AJ, Bradley DW, Houghton M (1991): Genetic organization and diversity of the hepatitis C virus. Proceedings of the National Academy of Sciences USA 88:2451-2455.
6. Dawson GJ, Chau KH, Cabal CM, Yarbough PO, Reyes GR, Mushahwar IK (1992): Solid-phase enzyme-linked immunosorbent assay for hepatitis E virus IgG and IgM antibodies utilizing recombinant antigens and synthetic peptides. Journal of Virological Methods 38:175-186.
7. Fagan EA, David SE, Tovey GM, Lloyd G, Smith HM, Portman B, Tan K-C, Zuckerman AJ, Williams R (1992): Toga Virus-like particles in acute liver failure attributed to sporadic non-A, non-B hepatitis and recurrence after liver transplantation. Journal of Medical Virology 38:71-77.
8. Felsenstein J (1993): PHYLIP Inference Package, Version 3.5c. Dept. of Genetics, University of Washington, Seattle, Distributed by the author.
9. Gorbalenya AE, Koonin EV (1989): Virus proteins containing the purine NTP-binding pattern. Nucleic Acids Research 17:8413-8440.
10. Grakoui A, McCourt DW, Wychowski C, Feinstone SM, Rice CM (1993a): A second hepatitis C virus-encoded proteinase. Proceedings of the National Academy of Sciences USA 90:10583-10587.
11. Grakoui A, McCourt DW, Wychowski C, Feinstone SM, Rice CM (1993b): Characterization of the hepatitis C virus-encoded serine proteinase: Determination of proteinase-dependent polyprotein cleavage sites. Journal of Virology 67:2832-2843.
12. Han JH, Shyamala V, Richman KH, Brauer MJ, Irvine B, Urdea MS, Tekamp-Olson P, Kuo G, Choo Q-L, Houghton M (1991): Characterization of the terminal regions of hepatitis C viral RNA: Identification of conserved sequences in the 5′ untranslated region and poly(A) tails at the 3′ end. Proceedings of the National Academy of Sciences USA 88:1711-1715.
13. Hijikata M, Kato N, Ootsuyama Y, Nakagawa M, Shimotohno K (1991): Gene mapping of the putative structural region of the hepatitis C virus genome by in vitri processing analysis. Proceedings of the National Academy of Sciences USA 88:5547-5551.
14. Koonin EV, Dolja VV (1993): Evolution and taxonomy of positivestrand RNA viruses: Implications of comparative analysis of amino acid sequences. Critical Reviews in Biochemistry and Molecular Biology 28:375-430
15. Kuo G, Choo Q-L, Alter HJ, Gitnick GL, Redeker AG, Purcell RH, Miyamura T, Dienstag JL, Alter MJ, Stevens CE, Tegtmeier GE, Bonino F, Colombo M, Lee W-S, Kuo C, Berger K, Shuster JR. Overby LR, Bradley DW, Houghton M (1989): An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science 244:362-364.
16. Kuwada SK, Patel VM, Hollinger B, Lin HJ, Yarbough PO, Wiesner RH, Kaese D, Rakela J (1994): Non-A, non-B fulminant hepatitis is also non-E and non-C. American Journal of Gastroenterology 89: 57-61.
17. Lin C, Lindenbach BD, Pragai BM, McCourt DW, Rice CM (1994): Processing in the hepatitis C virus E2-NS2 region: Identification of p7 and two distinct E2-specific products with different C termini. Journal of Virology 68:5063-5073.
18. Marcellin P, Martinot-Peignoux M, Gabriel F, Branger M, Degott C, Elias A, Xu LZ, Larzul D, Erlinger S, Benhamou JP (1993): Chronic non-B, non-C hepatitis among blood donors assessed with HCV third generation tests and polymerase chain reaction. Journal of Hepatology 19:167-170.
19. Mizushima H, Hijikata M, Asabe S, Hirota M, Kimura K, Shimotohno K (1994): Two hepatitis C virus glycoprotein E2 products with different C termini. Journal of Virology 68:6215-6222.
20. Muerhoff AS, Leary TP, Simons JN, Pilot-Matias TJ, Dawson GJ, Erker JC, Chalmers ML, Schlauder GG, Desai SM, Mushahwar IK (1995): Genomic organization of GBV-A and GBV-B: Two new members of the Flaviviridae associated with GB-agent hepatitis. Journal of Virology 69:5621-5630.
21. Okamoto H, Okada S, Sugiyama Y, Kurai K, Iizuka, Machida A, Miyakawa, Mayumi M (1991): Nucleotide sequence of the genomic RNA of hepatitis C virus isolated from a human carrier: Comparison with reported isolates for conserved and divergent regions. Journal of General Virology 72:2697-2704.
22. Sallie R, Silva AE, Purdy M, Smith H, McCaustland K, Tibbs C, Portmann B, Eddleston A, Bradley D, Williams R (1994): Hepatitis C and E in non-A non-B fulminant hepatic failure: A polymerase chain reaction and serological study. Journal of Hepatology 20: 580-588.
23. Schlauder GG, Mushahwar IK (1994): Detection of hepatitis C and E virus by the polymerase chain reaction. Journal of Virological Methods 47:243-253.
24. Schlauder GG, Dawson GJ, Simons JN, Pilot-Matias TJ, Guiterrez RA, Heynen CA, Knigge MF, Kurpiewski GS, Leary TP, Muerhoff AS, Desai SM, Mushahwar IK (1995): Molecular and serologic analysis in the transmission of the GB hepatitis agents. Journal of Medical Virology 46.81-90.
25. Simons JN, Pilot-Matias TJ, Leary TP, Dawson GJ, Desai SM, Schlauder GG, Muerhoff AS, Erker JC, Buijk SL, Chalmers ML, Van Sant CL, Mushahwar IK (1995a): Identification of two flavivirus-like genomes in the GB hepatitis agent. Proceedings of the National Academy of Sciences USA 192:3401-3405.
26. Simons JN, Leary TP, Dawson GJ, Pilot-Matias TJ, Muerhoff AS, Schlauder GG, Desai SM, Mushahwar IK (1995b): Isolation of novel virus-like sequences associated with human hepatitis. Nature Medicine 1:564-569.
27. Sorensen AB, Duch M, Jorgensen P, Pedersen FS (1993): Amplification and sequence analysis of DNA flanking integrated proviruses by a simple two-step polymerase chain reaction method. Journal of Virology 67:7118-7124.
28. Tassopoulos NC, Hatzakis A, Delladetsima I, Koutelou MG, Todoulos A, Miriagou V (1992): Role of hepatitis C virus in acute non-A, non-B hepatitis in Greece: A five-year prospective study. Gastroenterology 102:969-972.
29. vonHeijne G (1986): A new method for predicting signal sequence cleavage sites. Nucleic Acids Research 14:4683-4690.