-
1
-
-
19444364594
-
The other trinucleotide repeat: Polyalanine expansion disorders
-
DOI 10.1016/j.gde.2005.04.003, PII S0959437X05000559
-
Albrecht A, Mundlos S: The other trinucleotide repeat: polyalanine expansion disorders. Curr Opin Genet Dev 2005; 15:285-293. (Pubitemid 40726052)
-
(2005)
Current Opinion in Genetics and Development
, vol.15
, pp. 285-293
-
-
Albrecht, A.1
Mundlos, S.2
-
2
-
-
19544394236
-
A molecular pathogenesis for transcription factor associated poly-alanine tract expansions
-
DOI 10.1093/hmg/ddh277
-
Albrecht AN, Kornak U, Boddrich A, Suring K, Robinson PN, Stiege AC, Lurz R, Stricker S, Wanker EE, Mundlos S: A molecular patho-genesis for transcription factor associated poly-alanine tract expansions. Hum Mol Genet 2004; 13: 2351-2359. (Pubitemid 39377839)
-
(2004)
Human Molecular Genetics
, vol.13
, Issue.20
, pp. 2351-2359
-
-
Albrecht, A.N.1
Kornak, U.2
Boddrich, A.3
Suring, K.4
Robinson, P.N.5
Stiege, A.C.6
Lurz, R.7
Stricker, S.8
Wanker, E.E.9
Mundlos, S.10
-
3
-
-
77957002197
-
A screen for deubiquitinating enzymes involved in the g/m checkpoint identifies usp50 as A regulator of hsp90-dependent wee1 stabi lity
-
Aressy B, Jullien D, Cazales M, Marcellin M, Bugler B, Burlet-Schiltz O, Ducommun B: A screen for deubiquitinating enzymes involved in the G/M checkpoint identifies USP50 as a regulator of HSP90-dependent Wee1 stabi lity. Cell Cycle 2010; 9: 3815-3822.
-
(2010)
Cell Cycle
, vol.9
, pp. 3815-3822
-
-
Aressy, B.1
Jullien, D.2
Cazales, M.3
Marcellin, M.4
Bugler, B.5
Burlet-Schiltz, O.6
Ducommun, B.7
-
4
-
-
0347993069
-
Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress
-
DOI 10.1074/jbc.M309054200
-
Arlander SJ, Eapen AK, Vroman BT, McDonald RJ, Toft DO, Karnitz LM: Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress. J Biol Chem 2003; 278: 52572-52577. (Pubitemid 38035854)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.52
, pp. 52572-52577
-
-
Arlander, S.J.H.1
Eapen, A.K.2
Vroman, B.T.3
McDonald, R.J.4
Toft, D.O.5
Karnitz, L.M.6
-
5
-
-
0034326305
-
Sequence interruptions confer differential stability at microsatellite alleles in mismatch repair-deficient cel ls
-
Bacon AL, Farrington SM, Dunlop MG: Sequence interruptions confer differential stability at microsatellite alleles in mismatch repair-deficient cel ls. Hum Mol Genet 2000; 9: 2707-2713.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2707-2713
-
-
Bacon, A.L.1
Farrington, S.M.2
Dunlop, M.G.3
-
6
-
-
0026094779
-
Adaptive reversion of a frameshift mutation in Escherichia coli
-
Cairns J, Foster PL: Adaptive reversion of a frameshift mutation in Escherichia coli. Genetics 1991; 128: 695-701.
-
(1991)
Genetics
, vol.128
, pp. 695-701
-
-
Cairns, J.1
Foster, P.L.2
-
7
-
-
0242523875
-
Natural Selection and the Emergence of a Mutation Phenotype: An Update of the Evolutionary Synthesis Considering Mechanisms that Affect Genome Variation
-
DOI 10.1146/annurev.micro.57.030502.090855
-
Caporale LH: Natural selection and the emergence of a mutation phenotype: an update of the evolutionary synthesis considering mechanisms that affect genome variation. Annu Rev Microbiol 2003; 57: 467-485. (Pubitemid 37392952)
-
(2003)
Annual Review of Microbiology
, vol.57
, pp. 467-485
-
-
Caporale, L.H.1
-
8
-
-
78650446334
-
Friedman n, rando oj: Paternally induced trans-generational environmental reprogram-ming of metabolic gene expression in mammals
-
Carone BR, Fauquier L, Habib N, Shea JM, Hart CE, Li R, Bock C, Li C, Gu H, Zamore PD, Meissner A, Weng Z, Hofmann HA, Friedman N, Rando OJ: Paternally induced trans-generational environmental reprogram-ming of metabolic gene expression in mammals. Cell 2010; 143:1084-1096.
-
(2010)
Cell
, vol.143
, pp. 1084-1096
-
-
Carone, B.R.1
Fauquier, L.2
Habib, N.3
Shea, J.M.4
Hart, C.E.5
Li, R.6
Bock, C.7
Li, C.8
Gu, H.9
Zamore, P.D.10
Meissner, A.11
Weng, Z.12
Hofmann, H.A.13
-
9
-
-
0036578758
-
Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells
-
Cleary JD, Nichol K, Wang YH, Pearson CE: Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells. Nat Genet 2002; 31: 37-46.
-
(2002)
Nat Genet
, vol.31
, pp. 37-46
-
-
Cleary, J.D.1
Nichol, K.2
Wang, Y.H.3
Pearson, C.E.4
-
10
-
-
38949119752
-
Starvation induces genomic rearrangements and starvation-resilient phenotypes in yeast
-
DOI 10.1093/molbev/msm256
-
Coyle S, Kroll E: Starvation induces genomic rearrangements and starvation-resilient phe-notypes in yeast. Mol Biol Evol 2008; 25:310-318. (Pubitemid 351231602)
-
(2008)
Molecular Biology and Evolution
, vol.25
, Issue.2
, pp. 310-318
-
-
Coyle, S.1
Kroll, E.2
-
11
-
-
33749469341
-
Inhibition of Hsp90 compromises the DNA damage response to radiation
-
DOI 10.1158/0008-5472.CAN-06-2181
-
Dote H, Burgan WE, Camphausen K, Tofilon PJ: Inhibition of Hsp90 compromises the DNA damage response to radiation. Cancer Res 2006; 66: 9211-9220. (Pubitemid 44521142)
-
(2006)
Cancer Research
, vol.66
, Issue.18
, pp. 9211-9220
-
-
Dote, H.1
Burgan, W.E.2
Camphausen, K.3
Tofilon, P.J.4
-
12
-
-
68849126662
-
Enhanced radiosensitization of human glioma cells by combining inhibition of poly(ADP-ribose) polymerase with inhibition of heat shock protein 90
-
Dungey FA, Caldecott KW, Chalmers AJ: Enhanced radiosensitization of human glioma cells by combining inhibition of poly(ADP-ribose) polymerase with inhibition of heat shock protein 90. Mol Cancer Ther 2009; 8: 2243-2254.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2243-2254
-
-
Dungey, F.A.1
Caldecott, K.W.2
Chalmers, A.J.3
-
13
-
-
33644823855
-
Presence of mlh1 protein aggravates the potential of the hsp90 inhibitor radicicol to sensitize tumor cells to cisplatin
-
Fedier A, Stuedli A, Fink D: Presence of MLH1 protein aggravates the potential of the HSP90 inhibitor radicicol to sensitize tumor cells to cisplatin. Int J Oncol 2005; 27:1697-1705.
-
(2005)
Int J Oncol
, vol.27
, pp. 1697-1705
-
-
Fedier, A.1
Stuedli, A.2
Fink, D.3
-
14
-
-
0032775892
-
Contingency loci, mutator alleles, and their interactions. Synergistic strategies for microbial evolution and adaptation in pathogenesis
-
DOI 10.1111/j.1749-6632.1999.tb08907.x
-
Field D, Magnasco MO, Moxon ER, Metzgar D, Tanaka MM, Wills C, Thaler DS: Contingency loci, mutator alleles, and their interactions: synergistic strategies for microbial evolution and adaptation in pathogenesis. Ann NY Acad Sci 1999; 870:378-382. (Pubitemid 29349371)
-
(1999)
Annals of the New York Academy of Sciences
, vol.870
, pp. 378-382
-
-
Field, D.1
Magnasco, M.O.2
Moxon, E.R.3
Metzgar, D.4
Tanaka, M.M.5
Wills, C.6
Thaler, D.S.7
-
16
-
-
13144262863
-
Computerized polymorphic marker identification: Experimental validation and a predicted human polymorphism catalog
-
DOI 10.1073/pnas.95.13.7514
-
Fondon JW 3rd, Mele GM, Brezinschek RI, Cum-mings D, Pande A, Wren J, O'Brien KM, Kup-fer KC, Wei MH, Lerman M, Minna JD, Garner HR: Computerized polymorphic marker identification: experimental validation and a predicted human polymorphism catalog. Proc Natl Acad Sci USA 1998; 95: 7514-7519. (Pubitemid 28293284)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.13
, pp. 7514-7519
-
-
Fondon III, J.W.1
Mele, G.M.2
Brezinschek, R.I.3
Cummings, D.4
Pande, A.5
Wren, J.6
O'Brien, K.M.7
Kupfer, K.C.8
Wei, M.-H.9
Lerman, M.10
Minna, J.D.11
Garner, H.R.12
-
17
-
-
80052563657
-
Stress alters rates and types of loss of hetero-zygosity in candida albicans
-
Forche A, Abbey D, Pisithkul T, Weinzierl MA, R i ngs t rom T, Br uck D, Petersen K, Ber ma n J: Stress alters rates and types of loss of hetero-zygosity in Candida albicans. MBio 2011; 2:e00129-11.
-
(2011)
MBio
, vol.2
-
-
Forche, A.1
Abbey, D.2
Pisithkul, T.3
Weinzierl, M.A.4
Ringstrom, T.5
Bruck, D.6
Petersen, K.7
Berman, J.8
-
18
-
-
77956528497
-
Rosenberg sm, hastings pj: Separate DNA pol ii-and pol iv-dependent pathways of stress-induced mutation during double-strand-break repair in escherichia coli are controlled by rpos
-
Frisch RL, Su Y, Thornton PC, Gibson JL, Rosenberg SM, Hastings PJ: Separate DNA Pol II-and Pol IV-dependent pathways of stress-induced mutation during double-strand-break repair in Escherichia coli are controlled by RpoS. J Bacteriol 2010; 192: 4694-4700.
-
(2010)
J Bacteriol
, vol.192
, pp. 4694-4700
-
-
Frisch, R.L.1
Su, Y.2
Thornton, P.C.3
Gibson, J.L.4
-
19
-
-
67849086820
-
DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli
-
Galhardo RS, Do R, Yamada M, Friedberg EC, Hastings PJ, Nohmi T, Rosenberg SM: DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli. Genetics 20 09; 18 2: 55-68.
-
(2009)
Genetics
, vol.182
, pp. 55-68
-
-
Galhardo, R.S.1
Do, R.2
Yamada, M.3
Friedberg, E.C.4
Hastings, P.J.5
Nohmi, T.6
Rosenberg, S.M.7
-
21
-
-
79251560849
-
Drosophila piwi f u nct ions in hsp90-mediated suppression of pheno-typic variation
-
Gangaraju VK, Yin H, Weiner MM, Wang J, Huang X A, Lin H: Drosophila Piwi f u nct ions in Hsp90-mediated suppression of pheno-typic variation. Nat Genet 2011; 43:153-158.
-
(2011)
Nat Genet
, vol.43
, pp. 153-158
-
-
Gangaraju, V.K.1
Yin, H.2
Weiner, M.M.3
Wang, J.4
Huang, X.A.5
Lin, H.6
-
22
-
-
78149432728
-
Variable tandem repeats accelerate evolution of coding and regulatory sequences
-
Gemayel R, Vinces MD, Legendre M, Verstrepen KJ: Variable tandem repeats accelerate evolution of coding and regulatory sequences. Annu Rev Genet 2010; 44: 445-477.
-
(2010)
Annu Rev Genet
, vol.44
, pp. 445-477
-
-
Gemayel, R.1
Vinces, M.D.2
Legendre, M.3
Verstrepen, K.J.4
-
23
-
-
23444458415
-
Transcriptional activation modulated by homopolymeric glutamine and proline stretches
-
Gerber HP, Seipel K, Georgiev O, Hofferer M, Hug M, Rusconi S, Schaffner W: Transcrip-tional activation modulated by homopoly-meric glutamine and proline stretches. Science 1994; 263: 808-811. (Pubitemid 24093208)
-
(1994)
Science
, vol.263
, Issue.5148
, pp. 808-811
-
-
Gerber, H.-P.1
Seipel, K.2
Georgiev, O.3
Hofferer, M.4
Hug, M.5
Rusconi, S.6
Schaffner, W.7
-
24
-
-
77954354375
-
Rosenberg sm: The sigma(E) stress response is required for stress-induced mutation and amplification in escherichia coli
-
Gibson JL, Lombardo MJ, Thornton PC, Hu KH, Galhardo RS, Beadle B, Habib A, Magner DB, Frost LS, Herman C, Hastings PJ, Rosenberg sm: the sigma(E) stress response is required for stress-induced mutation and amplification in escherichia coli. Mol Microbiol 2010; 77:415-430.
-
(2010)
Mol Microbiol
, vol.77
, pp. 415-430
-
-
Gibson, J.L.1
Lombardo, M.J.2
Thornton, P.C.3
Hu, K.H.4
Galhardo, R.S.5
Beadle, B.6
Habib, A.7
Magner, D.B.8
Frost, L.S.9
Herman, C.10
Hastings, P.J.11
-
25
-
-
55249099793
-
Hastings pj, rosenberg sm: Mutability and importance of a hypermutable cell subpopula-tion that produces stress-induced mutants in escherichia coli
-
Gonzalez C, Hadany L, Ponder RG, Price M, Hastings PJ, Rosenberg SM: Mutability and importance of a hypermutable cell subpopula-tion that produces stress-induced mutants in Escherichia coli. PLoS Genet 2008; 4:e1000208.
-
(2008)
PLoS Genet
, vol.4
-
-
Gonzalez, C.1
Hadany, L.2
Ponder, R.G.3
Price, M.4
-
26
-
-
9744253732
-
Genome-wide demethylation destabilizes CTG-CAG trinucleotide repeats in mammalian cells
-
DOI 10.1093/hmg/ddh317
-
Gorbunova V, Seluanov A, Mittelman D, Wilson JH: Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalia n cel ls. Hum Mol Genet 2004; 13: 2979-2989. (Pubitemid 39585230)
-
(2004)
Human Molecular Genetics
, vol.13
, Issue.23
, pp. 2979-2989
-
-
Gorbunova, V.1
Seluanov, A.2
Mittelman, D.3
Wilson, J.H.4
-
27
-
-
79960134213
-
Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage
-
Ha K, Fiskus W, Rao R, Balusu R, Venkannagari S, Nalabothula NR, Bhalla KN: Hsp90 inhibitor-mediated disruption of chaperone association of ATR with Hsp90 sensitizes cancer cells to DNA damage. Mol Cancer Ther 2011; 10: 1194-1206.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 1194-1206
-
-
Ha, K.1
Fiskus, W.2
Rao, R.3
Balusu, R.4
Venkannagari, S.5
Nalabothula, N.R.6
Bhalla, K.N.7
-
28
-
-
0033289711
-
Transposable elements as activators of cryptic genes in E. coli
-
Hall BG: Transposable elements as activators of cryptic genes in E. coli. Genetica 1999; 107: 181-187. (Pubitemid 129574964)
-
(1999)
Genetica
, vol.107
, Issue.1-3
, pp. 181-187
-
-
Hall, B.G.1
-
29
-
-
20644472668
-
Genetics: Microsatellite instability generates diversity in brain and sociobehavioral traits
-
DOI 10.1126/science.1111427
-
Hammock EA, Young LJ: Microsatellite instability generates diversity in brain and sociobehav-ioral traits. Science 2005; 308:1630-1634. (Pubitemid 40807513)
-
(2005)
Science
, vol.308
, Issue.5728
, pp. 1630-1634
-
-
Hammock, E.A.D.1
Young, L.J.2
-
30
-
-
77956553257
-
Competition of escherichia coli DNA polymerases i, II and III with DNA pol IV in stressed cells
-
Hastings PJ, Hersh MN, Thornton PC, Fonville NC, Slack A, Frisch RL, Ray MP, Harris RS, Leal SM, Rosenberg SM: Competition of Escherichia coli DNA polymerases I, II and III with DNA Pol IV in stressed cells. PLoS One 2010; 5:e10862.
-
(2010)
PLoS One
, vol.5
-
-
Hastings, P.J.1
Hersh, M.N.2
Thornton, P.C.3
Fonville, N.C.4
Slack, A.5
Frisch, R.L.6
Ray, M.P.7
Harris, R.S.8
Leal, S.M.9
Rosenberg, S.M.10
-
31
-
-
59249105978
-
A microhomolog y-mediated break-induced replication model for the origin of human copy number variation
-
Hastings PJ, Ira G, Lupski JR: A microhomolog y-mediated break-induced replication model for the origin of human copy number variation. PLoS Genet 2009a;5:e1000327.
-
(2009)
PLoS Genet
, vol.5
-
-
Hastings, P.J.1
Ira, G.2
Lupski, J.R.3
-
33
-
-
39149094942
-
DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences
-
DOI 10.1093/nar/gkm1089
-
Hile SE, Eckert KA: DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide mic-rosatellite sequences. Nucleic Acids Res 2008; 36:688-696. (Pubitemid 351250458)
-
(2008)
Nucleic Acids Research
, vol.36
, Issue.2
, pp. 688-696
-
-
Hile, S.E.1
Eckert, K.A.2
-
35
-
-
0028788635
-
Mismatch repair in escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases
-
Jaworski A, Rosche WA, Gellibolian R, Kang S, Shimizu M, Bowater RP, Sinden RR, Wells RD: Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases. Proc Natl Acad Sci USA 1995; 92:11019-11023.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11019-11023
-
-
Jaworski, A.1
Rosche, W.A.2
Gellibolian, R.3
Kang, S.4
Shimizu, M.5
Bowater, R.P.6
Sinden, R.R.7
Wells, R.D.8
-
36
-
-
77957975815
-
Purified human brca2 stimulates rad51-mediated recombination
-
Jensen RB, Carreira A, Kowalczykowski SC: Purified human BRCA2 stimulates RAD51-mediated recombination. Nature 2010; 467: 678-683.
-
(2010)
Nature
, vol.467
, pp. 678-683
-
-
Jensen, R.B.1
Carreira, A.2
Kowalczykowski, S.C.3
-
37
-
-
55949134635
-
Dna-dependent protein ki-nase is involved in heat shock protein-mediated accumulation of hypoxia-inducible fac-tor-1alpha in hypoxic preconditioned hepg2 cells
-
Kang MJ, Jung SM, Kim MJ, Bae JH, Kim HB, Kim JY, Park SJ, Song HS, Kim DW, Kang CD, Kim SH: DNA-dependent protein ki-nase is involved in heat shock protein-mediated accumulation of hypoxia-inducible fac-tor-1alpha in hypoxic preconditioned HepG2 cells. FEBS J 2008; 275:5969-5981.
-
(2008)
FEBS J
, vol.275
, pp. 5969-5981
-
-
Kang, M.J.1
Jung, S.M.2
Kim, M.J.3
Bae, J.H.4
Kim, H.B.5
Kim, J.Y.6
Park, S.J.7
Song, H.S.8
Kim, D.W.9
Kang, C.D.10
Kim, S.H.11
-
38
-
-
23744447715
-
Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells
-
DOI 10.1083/jcb.200411083
-
Kim JS, Krasieva TB, Kurumizaka H, Chen DJ, Taylor AM, Yokomori K: Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells. J Cell Biol 2005; 17 0: 341-347. (Pubitemid 41126934)
-
(2005)
Journal of Cell Biology
, vol.170
, Issue.3
, pp. 341-347
-
-
Kim, J.-S.1
Krasieva, T.B.2
Kurumizaka, H.3
Chen, D.J.4
Taylor, A.M.R.5
Yokomori, K.6
-
39
-
-
0014421064
-
Evolutionary rate at the molecular level
-
Kimura M: Evolutionary rate at the molecular level. Nature 1968; 217: 624-626.
-
(1968)
Nature
, vol.217
, pp. 624-626
-
-
Kimura, M.1
-
40
-
-
34547208016
-
Indirect selection for mutability
-
King DG, Kashi Y: Indirect selection for mutability. Heredity 20 07; 99: 123-124.
-
(2007)
Heredity
, vol.99
, pp. 123-124
-
-
King, D.G.1
Kashi, Y.2
-
41
-
-
34249337762
-
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells
-
DOI 10.1038/nature05778, PII NATURE05778
-
Kovtun IV, Liu Y, Bjoras M, Klungland A, Wilson SH, McMurray CT: OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells. Nature 2007; 447: 447-452. (Pubitemid 46816735)
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 447-452
-
-
Kovtun, I.V.1
Liu, Y.2
Bjoras, M.3
Klungland, A.4
Wilson, S.H.5
McMurray, C.T.6
-
42
-
-
3142775655
-
The modern theory of biological evolution: An expanded synthesis
-
Kutschera U, Niklas KJ: The modern theory of biological evolution: an expanded synthesis. Naturwissenschaften 2004; 91:255-276. (Pubitemid 38916481)
-
(2004)
Naturwissenschaften
, vol.91
, Issue.6
, pp. 255-276
-
-
Kutschera, U.1
Niklas, K.J.2
-
43
-
-
0142062024
-
Error-prone DNA polymerase IV is controlled by the stress-response sigma factor, RpoS, in Escherichia coli
-
DOI 10.1046/j.1365-2958.2003.03704.x
-
Layton JC, Foster PL: Error-prone DNA poly-merase IV is controlled by the stress-response sigma factor, RpoS, in Escherichia coli. Mol Microbiol 2003; 50: 549-561. (Pubitemid 37297134)
-
(2003)
Molecular Microbiology
, vol.50
, Issue.2
, pp. 549-561
-
-
Layton, J.C.1
Foster, P.L.2
-
44
-
-
38849170546
-
Sequence-based estimation of minisatellite and microsatellite repeat variability
-
DOI 10.1101/gr.6554007
-
Legendre M, Pochet N, Pak T, Verstrepen KJ: Sequence-based estimation of minisatellite and microsatellite repeat variability. Genome Res 2007; 17:1787-1796. (Pubitemid 351360003)
-
(2007)
Genome Research
, vol.17
, Issue.12
, pp. 1787-1796
-
-
Legendre, M.1
Pochet, N.2
Pak, T.3
Verstrepen, K.J.4
-
45
-
-
78649906060
-
Dnmt3a mutations in acute myeloid leukemia
-
Ley TJ, Ding L, Walter MJ, McLellan MD, et al: DNMT3A mutations in acute myeloid leukemia. N Engl J Med 2010; 363: 2424-2433.
-
(2010)
N Engl J Med
, vol.363
, pp. 2424-2433
-
-
Ley, T.J.1
Ding, L.2
Walter, M.J.3
McLellan, M.D.4
-
46
-
-
34548204316
-
Transcription-induced CAG repeat contraction in human cells is mediated in part by transcription-coupled nucleotide excision repair
-
DOI 10.1128/MCB.00739-07
-
Lin Y, Wilson JH: Transcription-induced CAG repeat contraction in human cells is mediated in part by transcription-coupled nucle-otide excision repair. Mol Cell Biol 2007; 27: 6209-6217. (Pubitemid 47326707)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.17
, pp. 6209-6217
-
-
Lin, Y.1
Wilson, J.H.2
-
47
-
-
77957804215
-
Human brca2 protein promotes rad51 filament formation on rpa-covered single-stranded dna
-
Liu J, Doty T, Gibson B, Heyer WD: Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA. Nat Struct Mol Biol 2010; 17:1260-1262.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1260-1262
-
-
Liu, J.1
Doty, T.2
Gibson, B.3
Heyer, W.D.4
-
48
-
-
0035870243
-
A mutator phenotype in cancer
-
Loeb LA: A mutator phenotype in cancer. Cancer Res 2001; 61:3230-3239. (Pubitemid 32695004)
-
(2001)
Cancer Research
, vol.61
, Issue.8
, pp. 3230-3239
-
-
Loeb, L.A.1
-
49
-
-
1642354817
-
General Stress Response Regulator RpoS in Adaptive Mutation and Amplification in Escherichia coli
-
DOI 10.1534/genetics.166.2.669
-
Lombardo MJ, Aponyi I, Rosenberg SM: General stress response regulator rpos in adaptive mutation and amplification in escherichia coli. Genetics 2004; 16 6:669-680. (Pubitemid 38391733)
-
(2004)
Genetics
, vol.166
, Issue.2
, pp. 669-680
-
-
Lombardo, M.-J.1
Aponyi, I.2
Rosenberg, S.M.3
-
50
-
-
77649144557
-
Repeat instability as the basis for human diseases and as a potential target for therapy
-
Lopez Castel A, Cleary JD, Pearson CE: Repeat instability as the basis for human diseases and as a potential target for therapy. Nat Rev Mol Cell Biol 2010; 11: 16 5-17 0.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 165-170
-
-
Lopez Castel, A.1
Cleary, J.D.2
Pearson, C.E.3
-
51
-
-
0001641514
-
Mutations of bacteria from virus sensitivity to virus resistance
-
Luria SE, Delbrück M: Mutations of bacteria from virus sensitivity to virus resistance. Genetics 1943; 28:491-511.
-
(1943)
Genetics
, vol.28
, pp. 491-511
-
-
Luria, S.E.1
Delbrück, M.2
-
52
-
-
77955237293
-
Trans-poson tn7 preferentially inserts into GAA*TTC triplet repeats under conditions conducive to Y*r*Y triplex formation
-
Mancuso M, Sammarco MC, Grabczyk E: Trans-poson Tn7 preferentially inserts into GAA*TTC triplet repeats under conditions conducive to Y*R*Y triplex formation. PLoS One 2010; 5:e11121.
-
(2010)
PLoS One
, vol.5
-
-
Mancuso, M.1
Sammarco, M.C.2
Grabczyk, E.3
-
53
-
-
47249095041
-
Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks
-
DOI 10.1093/nar/gkn347
-
Mansour WY, Schumacher S, Rosskopf R, Rhein T, S c h m i d t-Peters en F, G at z emei e r F, H a ag F, Borgmann K, Willers H, Dahm-Daphi J: Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks. Nucleic Acids Res 2008; 36:4088-4098. (Pubitemid 351984824)
-
(2008)
Nucleic Acids Research
, vol.36
, Issue.12
, pp. 4088-4098
-
-
Mansour, W.Y.1
Schumacher, S.2
Rosskopf, R.3
Rhein, T.4
Schmidt-Petersen, F.5
Gatzemeier, F.6
Haag, F.7
Borgmann, K.8
Willers, H.9
Dahm-Daphi, J.10
-
54
-
-
0141780849
-
Fidelity of primate cell repair of a double-strand break within a (CTG)·(CAG) tract: Effect of slipped DNA structures
-
DOI 10.1074/jbc.M304284200
-
Marcadier JL, Pearson CE: Fidelity of primate cell repair of a double-strand break within a (CTG).(CAG) tract. Effect of slipped DNA structures. J Biol Chem 2003; 278: 33848-33856. (Pubitemid 37553219)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.36
, pp. 33848-33856
-
-
Marcadier, J.L.1
Pearson, C.E.2
-
55
-
-
79961165129
-
Molecular chaperone hsp90 regulates rev1-mediated mut a gene sis
-
Mayca Pozo F, Oda T, Sekimoto T, Murakumo Y, Masutani C, Hanaoka F, Yamashita T: Molecular chaperone Hsp90 regulates REV1-mediated mut a gene sis. Mol Cel l Biol 2011; 31: 3396-3409.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 3396-3409
-
-
Mayca Pozo, F.1
Oda, T.2
Sekimoto, T.3
Murakumo, Y.4
Masutani, C.5
Hanaoka, F.6
Yamashita, T.7
-
56
-
-
0034612282
-
The SOS response regulates adaptive mutation
-
DOI 10.1073/pnas.120161797
-
McKenzie GJ, Harris RS, Lee PL, Rosenberg SM: The SOS response regulates adaptive mutation. Proc Natl Acad Sci USA 2000; 97: 6646-6651. (Pubitemid 30412768)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.12
, pp. 6646-6651
-
-
McKenzie, G.J.1
Harris, R.S.2
Lee, P.L.3
Rosenberg, S.M.4
-
57
-
-
77955716080
-
Hsp90 modulates CAG repeat insta-bi lit y i n huma n cells
-
Mittelman D, Sykoudis K, Hersh M, Lin Y, Wilson JH: Hsp90 modulates CAG repeat insta-bi lit y i n huma n cells. C ell St ress Chaperones 2010; 15:753-759.
-
(2010)
Cell Stress Chaperones
, vol.15
, pp. 753-759
-
-
Mittelman, D.1
Sykoudis, K.2
Hersh, M.3
Lin, Y.4
Jh, W.5
-
59
-
-
33845648557
-
Bacterial contingency loci: The role of simple sequence DNA repeats in bacterial adaptation
-
DOI 10.1146/annurev.genet.40.110405.090442
-
Moxon R, Bayliss C, Hood D: Bacterial contingency loci: the role of simple sequence DNA repeats in bacterial adaptation. Annu Rev Genet 2006; 40:307-333. (Pubitemid 44956788)
-
(2006)
Annual Review of Genetics
, vol.40
, pp. 307-333
-
-
Moxon, R.1
Bayliss, C.2
Hood, D.3
-
60
-
-
20544466648
-
Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition
-
DOI 10.1038/nature03663
-
Muotri AR, Chu VT, Marchetto MC, Deng W, Moran JV, Gage FH: Somatic mosaicism in neuronal precursor cells mediated by L1 ret-rotransposition. Nature 2005; 435:903-910. (Pubitemid 40896309)
-
(2005)
Nature
, vol.435
, Issue.7044
, pp. 903-910
-
-
Muotri, A.R.1
Chu, V.T.2
Marchetto, M.C.N.3
Deng, W.4
Moran, J.V.5
Gage, F.H.6
-
61
-
-
0030794661
-
A 140-bp-long palindromic sequence induces double-strand breaks during meiosis in the yeast Saccharomyces cerevisiae
-
Nag DK, Kurst A: A 140-bp-long palindromic sequence induces double-strand breaks during meiosis in the yeast Saccharomyces cerevisi-ae. Genetics 1997; 14 6: 835-847. (Pubitemid 27290970)
-
(1997)
Genetics
, vol.146
, Issue.3
, pp. 835-847
-
-
Nag, D.K.1
Kurst, A.2
-
62
-
-
33750696349
-
Inhibition of homologous recombination repair in irradiated tumor cells pretreated with Hsp90 inhibitor 17-allylamino-17-deme-thoxygeldanamycin
-
Noguchi M, Yu D, Hirayama R, Ninomiya Y, Se-kine E, Kubota N, Ando K, Okayasu R: Inhibition of homologous recombination repair in irradiated tumor cells pretreated with Hsp90 inhibitor 17-allylamino-17-deme-thoxygeldanamycin. Biochem Biophys Res Commun 2006; 351: 658-6 63.
-
(2006)
Biochem Biophys Res Commun
, vol.351
, pp. 658-663
-
-
Noguchi, M.1
Yu, D.2
Hirayama, R.3
Ninomiya, Y.4
Se-Kine, E.5
Kubota, N.6
Ando, K.7
Okayasu, R.8
-
63
-
-
34249727193
-
Hsp90 regulates the Fanconi anemia DNA damage response pathway
-
DOI 10.1182/blood-2006-08-038638
-
Oda T, Hayano T, Miyaso H, Takahashi N, Yamashita T: Hsp90 regulates the Fanconi anemia DNA damage response pathway. Blood 2007; 10 9: 5016-5026. (Pubitemid 46827802)
-
(2007)
Blood
, vol.109
, Issue.11
, pp. 5016-5026
-
-
Oda, T.1
Hayano, T.2
Miyaso, H.3
Takahashi, N.4
Yamashita, T.5
-
64
-
-
65549159662
-
Unstable nucleotide repeat minireview series: A molecular biography of unstable repeat disorders
-
Orr HT: Unstable nucleotide repeat minireview series: a molecular biography of unstable repeat disorders. J Biol Chem 2009; 284:7405.
-
(2009)
J Biol Chem
, vol.284
, pp. 7405
-
-
Orr, H.T.1
-
65
-
-
78650085850
-
Transcription of AAT at T T riple Trepeats in escherichia coli is silenced by H-NS and is1e transposition
-
Pan X, Liao Y, Liu Y, Chang P, Liao L, Yang L, Li H: Transcription of A AT AT T tripletrepeats in Escherichia coli is silenced by H-NS and IS1E transposition. PLoS One 2010; 5:e14271.
-
(2010)
PLoS One
, vol.5
-
-
Pan, X.1
Liao, Y.2
Liu, Y.3
Chang, P.4
Liao, L.5
Yang, L.6
Li, H.7
-
66
-
-
0037133931
-
In vitro (CTG)·(CAG) expansions and deletions by human cell extracts
-
DOI 10.1074/jbc.M109761200
-
Panigrahi GB, Cleary JD, Pearson CE: In vitro (CTG)·(CAG) expansions and deletions by human cell extracts. J Biol Chem 2002; 277: 13926-13934. (Pubitemid 34967999)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.16
, pp. 13926-13934
-
-
Panigrahi, G.B.1
Cleary, J.D.2
Pearson, C.E.3
-
67
-
-
0034674058
-
Length of ctg.cag repeats determines the influence of mismatch repair on genetic instability
-
Parniewski P, Jaworski A, Wells RD, Bowater RP: Length of CTG.CAG repeats determines the influence of mismatch repair on genetic instability. J Mol Biol 2000; 299:865-874.
-
(2000)
J Mol Biol
, vol.299
, pp. 865-874
-
-
Parniewski, P.1
Jaworski, A.2
Wells, R.D.3
Bowater, R.P.4
-
68
-
-
37249030834
-
Is evolvability evolvable?
-
DOI 10.1038/nrg2278, PII NRG2278
-
Pigliucci M: Is evolvability evolvable? Nat Rev Genet 2008; 9: 75-82. (Pubitemid 350277301)
-
(2008)
Nature Reviews Genetics
, vol.9
, Issue.1
, pp. 75-82
-
-
Pigliucci, M.1
-
69
-
-
24944477416
-
A switch from high-fidelity to error-prone DNA double-strand break repair underlies stress-induced mutation
-
DOI 10.1016/j.molcel.2005.07.025, PII S1097276505015224
-
Ponder RG, Fonville NC, Rosenberg SM: A switch from high-fidelity to error-prone DNA double-strand break repair underlies stress-induced mutation. Mol Cell 2005; 19: 791-804. (Pubitemid 41316673)
-
(2005)
Molecular Cell
, vol.19
, Issue.6
, pp. 791-804
-
-
Ponder, R.G.1
Fonville, N.C.2
Rosenberg, S.M.3
-
70
-
-
33847208871
-
Timescales of genetic and epigenetic inheritance
-
Rando OJ, Verstrepen KJ: Timescales of genetic and epigenetic inheritance. Cell 2007; 128: 655-668.
-
(2007)
Cell
, vol.128
, pp. 655-668
-
-
Rando, O.J.1
Verstrepen, K.J.2
-
71
-
-
0024469392
-
The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants
-
DOI 10.1038/342396a0
-
Rayssiguier C, Thaler DS, Radman M: The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants. Nature 1989; 342: 396-401. (Pubitemid 19277515)
-
(1989)
Nature
, vol.342
, Issue.6248
, pp. 396-401
-
-
Rayssiguier, C.1
Thaler, D.S.2
Radman, M.3
-
72
-
-
0035812702
-
Conversion of a peroxiredoxin into a disulfide reductase by a triplet repeat expansion
-
DOI 10.1126/science.1063143
-
Ritz D, Lim J, Reynolds CM, Poole LB, Beckwith J: Conversion of a peroxiredoxin into a disul-fide reductase by a triplet repeat expansion. Science 2001; 294:158-160. (Pubitemid 32952968)
-
(2001)
Science
, vol.294
, Issue.5540
, pp. 158-160
-
-
Ritz, D.1
Lim, J.2
Reynolds, C.M.3
Poole, L.B.4
Beckwith, J.5
-
73
-
-
79955799175
-
Double-strand break repair-independent role for brca2 in blocking stalled replication fork degradation by mre11
-
Schlacher K, Christ N, Siaud N, Egashira A, Wu H, Jasin M: Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11. Cell 2011; 145:529-542.
-
(2011)
Cell
, vol.145
, pp. 529-542
-
-
Schlacher, K.1
Christ, N.2
Siaud, N.3
Egashira, A.4
Wu, H.5
Jasin, M.6
-
74
-
-
0031057683
-
Destabilization of CAG trinucleotide repeat tracts by mismatch repair mutations in yeast
-
DOI 10.1093/hmg/6.3.349
-
Schweitzer JK, Livingston DM: Destabilization of CAG trinucleotide repeat tracts by mismatch repair mutations in yeast. Hum Mol Genet 1997; 6: 349-355. (Pubitemid 27116454)
-
(1997)
Human Molecular Genetics
, vol.6
, Issue.3
, pp. 349-355
-
-
Schweitzer, J.K.1
Livingston, D.M.2
-
75
-
-
74049129007
-
The molecular chaperone hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in uv-irradiated cells
-
Sekimoto T, Oda T, Pozo FM, Murakumo Y, Masutani C, Hanaoka F, Yamashita T: The molecular chaperone Hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in UV-irradiated cells. Mol Cell 2010; 37: 79-89.
-
(2010)
Mol Cell
, vol.37
, pp. 79-89
-
-
Sekimoto, T.1
Oda, T.2
Pozo, F.M.3
Murakumo, Y.4
Masutani, C.5
Hanaoka, F.6
Yamashita, T.7
-
76
-
-
80051961878
-
Impact of a stress-inducible switch to mutagenic repair of DNA breaks on mutation in Escherichia coli
-
Shee C, Gibson JL, Darrow MC, Gonzalez C, Rosenberg SM: Impact of a stress-inducible switch to mutagenic repair of DNA breaks on mutation in Escherichia coli. Proc Natl Acad Sci USA 2011; 10 8: 13 6 59-13 6 6 4.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 13659-13664
-
-
Shee, C.1
Gibson, J.L.2
Darrow, M.C.3
Gonzalez, C.4
Rosenberg, S.M.5
-
77
-
-
0032997736
-
MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers
-
Simpkins SB, Bocker T, Swisher EM, Mutch DG, Gersell DJ, Kovatich AJ, Palazzo JP, Fishel R, Goodfellow PJ: MLH1 promoter methyla-tion and gene silencing is the primary cause of microsatellite instability in sporadic en-dometrial cancers. Hum Mol Genet 1999; 8: 661-666. (Pubitemid 29139981)
-
(1999)
Human Molecular Genetics
, vol.8
, Issue.4
, pp. 661-666
-
-
Simpkins, S.B.1
Bocker, T.2
Swisher, E.M.3
Mutch, D.G.4
Gersell, D.J.5
Kovatich, A.J.6
Palazzo, J.P.7
Fishel, R.8
Goodfellow, P.J.9
-
79
-
-
76349117871
-
Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons
-
Specchia V, Piacentini L, Tritto P, Fanti L, D'Alessandro R, Palumbo G, Pimpinelli S, Bozzetti MP: Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons. Nature 2010; 463: 662-665.
-
(2010)
Nature
, vol.463
, pp. 662-665
-
-
Specchia, V.1
Piacentini, L.2
Tritto, P.3
Fanti, L.4
D'Alessandro, R.5
Palumbo, G.6
Pimpinelli, S.7
Bozzetti, M.P.8
-
80
-
-
5644277503
-
Mismatch repair proteins: Key regulators of genetic recombination
-
DOI 10.1159/000080593
-
Surtees JA, Argueso JL, Alani E: Mismatch repair proteins: key regulators of genetic recombination. Cytogenet Genome Res 2004; 107:14 6-159. (Pubitemid 39370377)
-
(2004)
Cytogenetic and Genome Research
, vol.107
, Issue.3-4
, pp. 146-159
-
-
Surtees, J.A.1
Argueso, J.L.2
Alani, E.3
-
81
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
TCGA
-
TCGA: Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008; 455:1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
82
-
-
79951678012
-
Reg ulation of PIDD auto-proteolysis and activity by the molecular chaperone hsp90
-
Tinel A, Eckert MJ, Logette E, Lippens S, Jans-sens S, Jaccard B, Quadroni M, Tschopp J: Reg ulation of PIDD auto-proteolysis and activity by the molecular chaperone Hsp90. Cell Death Dif fer 2011; 18: 506-515.
-
(2011)
Cell Death Dif Fer
, vol.18
, pp. 506-515
-
-
Tinel, A.1
Eckert, M.J.2
Logette, E.3
Lippens, S.4
Jans-Sens, S.5
Jaccard, B.6
Quadroni, M.7
Tschopp, J.8
-
83
-
-
0030924613
-
Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutation
-
DOI 10.1093/emboj/16.11.3303
-
Torkelson J, Harris RS, Lombardo MJ, Nagen-dran J, Thulin C, Rosenberg SM: Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutation. EMBO J 1997; 16:3303-3311. (Pubitemid 27234967)
-
(1997)
EMBO Journal
, vol.16
, Issue.11
, pp. 3303-3311
-
-
Torkelson, J.1
Harris, R.S.2
Lombardo, M.-J.3
Nagendran, J.4
Thulin, C.5
Rosenberg, S.M.6
-
84
-
-
25144494777
-
Intragenic tandem repeats generate functional variability
-
DOI 10.1038/ng1618, PII NG1618
-
Verstrepen KJ, Jansen A, Lewitter F, Fink GR: In-tragenic tandem repeats generate functional variability. Nat Genet 2005; 37: 986-990. (Pubitemid 43086157)
-
(2005)
Nature Genetics
, vol.37
, Issue.9
, pp. 986-990
-
-
Verstrepen, K.J.1
Jansen, A.2
Lewitter, F.3
Fink, G.R.4
-
85
-
-
66349113764
-
Unstable tandem repeats in promoters confer transcriptional evolv-ability
-
Vinces MD, Legendre M, Caldara M, Hagihara M, Verstrepen KJ: Unstable tandem repeats in promoters confer transcriptional evolv-ability. Science 2009; 324:1213-1216.
-
(2009)
Science
, vol.324
, pp. 1213-1216
-
-
Vinces, M.D.1
Legendre, M.2
Caldara, M.3
Hagihara, M.4
Verstrepen, K.J.5
-
86
-
-
58049215497
-
DNA structure-induced ge-nomic instability in vivo
-
Wang G, Carbajal S, Vijg J, DiGiovanni J, Vasquez KM: DNA structure-induced ge-nomic instability in vivo. J Natl Cancer Inst 2008; 100:1815-1817.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 1815-1817
-
-
Wang, G.1
Carbajal, S.2
Vijg, J.3
Digiovanni, J.4
Vasquez, K.M.5
-
87
-
-
0031729225
-
Mutators and long-term molecular evolution of pathogenic Escherichia coli O157:H7
-
Whittam TS, Reid SD, Selander RK: Mutators and long-term molecular evolution of pathogenic Escherichia coli O157:H7. Emerg Infect Dis 1998; 4:615-617. (Pubitemid 28553685)
-
(1998)
Emerging Infectious Diseases
, vol.4
, Issue.4
, pp. 615-617
-
-
Whittam, T.S.1
Reid, S.D.2
Selander, R.K.3
-
88
-
-
14844355218
-
High-resolution genome-wide mapping of transposon integration in mammals
-
DOI 10.1128/MCB.25.6.2085-2094.2005
-
Yant SR, Wu X, Huang Y, Garrison B, Burgess SM, Kay MA: High-resolution genome-wide mapping of transposon integration in mammals. Mol Cell Biol 2005; 25: 2085-2094. (Pubitemid 40354609)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.6
, pp. 2085-2094
-
-
Yant, S.R.1
Wu, X.2
Huang, Y.3
Garrison, B.4
Burgess, S.M.5
Kay, M.A.6
-
89
-
-
73349086578
-
A novel mechanism of transposon-mediated gene activation
-
Zhang Z, Saier MH Jr: A novel mechanism of transposon-mediated gene activation. PLoS Genet 2009; 5:e1000689.
-
(2009)
PLoS Genet
, vol.5
-
-
Zhang, Z.1
Saier Jr., M.H.2
|