메뉴 건너뛰기




Volumn 52, Issue 2, 2012, Pages 317-322

Unraveling the secrets of a double life: Contractile versus signaling Ca 2+ in a cardiac myocyte

Author keywords

Calcium; Contraction; Heart; Hypertrophy; Signaling

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL L TYPE; CALCIUM ION; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; RYANODINE RECEPTOR 2; SODIUM PROTON EXCHANGE PROTEIN 1; TRANSCRIPTION FACTOR NFAT; TRANSIENT RECEPTOR POTENTIAL CHANNEL;

EID: 84856009646     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2011.05.001     Document Type: Review
Times cited : (59)

References (79)
  • 1
    • 43549098268 scopus 로고    scopus 로고
    • Calcium cycling and signaling in cardiac myocytes
    • Bers D.M. Calcium cycling and signaling in cardiac myocytes. Annu Rev Physiol 2008, 70:23-49.
    • (2008) Annu Rev Physiol , vol.70 , pp. 23-49
    • Bers, D.M.1
  • 2
    • 0032540267 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
    • Molkentin J.D., Lu J.R., Antos C.L., Markham B., Richardson J., Robbins J., et al. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell Apr 17 1998, 93(2):215-228.
    • (1998) Cell , vol.93 , Issue.2 , pp. 215-228
    • Molkentin, J.D.1    Lu, J.R.2    Antos, C.L.3    Markham, B.4    Richardson, J.5    Robbins, J.6
  • 3
    • 77950470200 scopus 로고    scopus 로고
    • Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model
    • van Oort R.J., Respress J.L., Li N., Reynolds C., De Almeida A.C., Skapura D.G., et al. Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model. Hypertension Apr 2010, 55(4):932-938.
    • (2010) Hypertension , vol.55 , Issue.4 , pp. 932-938
    • van Oort, R.J.1    Respress, J.L.2    Li, N.3    Reynolds, C.4    De Almeida, A.C.5    Skapura, D.G.6
  • 5
    • 0035830362 scopus 로고    scopus 로고
    • A Ca(2+)-dependent transgenic model of cardiac hypertrophy: a role for protein kinase Calpha
    • Muth J.N., Bodi I., Lewis W., Varadi G., Schwartz A. A Ca(2+)-dependent transgenic model of cardiac hypertrophy: a role for protein kinase Calpha. Circulation Jan 2 2001, 103(1):140-147.
    • (2001) Circulation , vol.103 , Issue.1 , pp. 140-147
    • Muth, J.N.1    Bodi, I.2    Lewis, W.3    Varadi, G.4    Schwartz, A.5
  • 6
    • 33748323383 scopus 로고    scopus 로고
    • Regulation of cardiac hypertrophy by intracellular signalling pathways
    • Heineke J., Molkentin J.D. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol Aug 2006, 7(8):589-600.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , Issue.8 , pp. 589-600
    • Heineke, J.1    Molkentin, J.D.2
  • 7
    • 78650710691 scopus 로고    scopus 로고
    • Molecular pathways underlying cardiac remodeling during pathophysiological stimulation
    • Dec 21
    • Kehat I, Molkentin JD. Molecular pathways underlying cardiac remodeling during pathophysiological stimulation. Circulation Dec 21 2010;122(25):2727-35.
    • (2010) Circulation , vol.122 , Issue.25 , pp. 2727-35
    • Kehat, I.1    Molkentin, J.D.2
  • 8
    • 60449094498 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Lloyd-Jones D., Adams R., Carnethon M., De Simone G., Ferguson T.B., Flegal K., et al. Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation Jan 27 2009, 119(3):480-486.
    • (2009) Circulation , vol.119 , Issue.3 , pp. 480-486
    • Lloyd-Jones, D.1    Adams, R.2    Carnethon, M.3    De Simone, G.4    Ferguson, T.B.5    Flegal, K.6
  • 9
    • 0038125598 scopus 로고    scopus 로고
    • Calcium signalling: dynamics, homeostasis and remodelling
    • Berridge M.J., Bootman M.D., Roderick H.L. Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol Jul 2003, 4(7):517-529.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , Issue.7 , pp. 517-529
    • Berridge, M.J.1    Bootman, M.D.2    Roderick, H.L.3
  • 10
    • 23744438810 scopus 로고    scopus 로고
    • Calcium signaling in cardiac ventricular myocytes
    • Bers D.M., Guo T. Calcium signaling in cardiac ventricular myocytes. Ann NY Acad Sci Jun 2005, 1047:86-98.
    • (2005) Ann NY Acad Sci , vol.1047 , pp. 86-98
    • Bers, D.M.1    Guo, T.2
  • 11
    • 77956882103 scopus 로고    scopus 로고
    • Molecular mechanisms of adrenergic stimulation in the heart
    • Sampson K.J., Kass R.S. Molecular mechanisms of adrenergic stimulation in the heart. Heart Rhythm Aug 2010, 7(8):1151-1153.
    • (2010) Heart Rhythm , vol.7 , Issue.8 , pp. 1151-1153
    • Sampson, K.J.1    Kass, R.S.2
  • 13
    • 0027932798 scopus 로고
    • Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation
    • Luo W., Grupp I.L., Harrer J., Ponniah S., Grupp G., Duffy J.J., et al. Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation. Circ Res Sep 1994, 75(3):401-409.
    • (1994) Circ Res , vol.75 , Issue.3 , pp. 401-409
    • Luo, W.1    Grupp, I.L.2    Harrer, J.3    Ponniah, S.4    Grupp, G.5    Duffy, J.J.6
  • 17
    • 76549096632 scopus 로고    scopus 로고
    • 2+ loading preceded by a hypercontractile state and diastolic failure in the alpha(1C)TG mouse
    • 2+ loading preceded by a hypercontractile state and diastolic failure in the alpha(1C)TG mouse. PLoS One 2009, 4(1):e4133.
    • (2009) PLoS One , vol.4 , Issue.1
    • Wang, S.1    Ziman, B.2    Bodi, I.3    Rubio, M.4    Zhou, Y.Y.5    D'Souza, K.6
  • 19
    • 79551611533 scopus 로고    scopus 로고
    • Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy
    • Chen X., Nakayama H., Zhang X., Ai X., Harris D.M., Tang M., et al. Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy. J Mol Cell Cardiol Mar 2011, 50(3):460-470.
    • (2011) J Mol Cell Cardiol , vol.50 , Issue.3 , pp. 460-470
    • Chen, X.1    Nakayama, H.2    Zhang, X.3    Ai, X.4    Harris, D.M.5    Tang, M.6
  • 20
    • 0034695602 scopus 로고    scopus 로고
    • Electrical stimulation of neonatal cardiac myocytes activates the NFAT3 and GATA4 pathways and up-regulates the adenylosuccinate synthetase 1 gene
    • Xia Y., McMillin J.B., Lewis A., Moore M., Zhu W.G., Williams R.S., et al. Electrical stimulation of neonatal cardiac myocytes activates the NFAT3 and GATA4 pathways and up-regulates the adenylosuccinate synthetase 1 gene. J Biol Chem Jan 21 2000, 275(3):1855-1863.
    • (2000) J Biol Chem , vol.275 , Issue.3 , pp. 1855-1863
    • Xia, Y.1    McMillin, J.B.2    Lewis, A.3    Moore, M.4    Zhu, W.G.5    Williams, R.S.6
  • 21
    • 33745431025 scopus 로고    scopus 로고
    • Activity- and calcineurin-independent nuclear shuttling of NFATc1, but not NFATc3, in adult skeletal muscle fibers
    • Shen T., Liu Y., Cseresnyes Z., Hawkins A., Randall W.R., Schneider M.F. Activity- and calcineurin-independent nuclear shuttling of NFATc1, but not NFATc3, in adult skeletal muscle fibers. Mol Biol Cell Apr 2006, 17(4):1570-1582.
    • (2006) Mol Biol Cell , vol.17 , Issue.4 , pp. 1570-1582
    • Shen, T.1    Liu, Y.2    Cseresnyes, Z.3    Hawkins, A.4    Randall, W.R.5    Schneider, M.F.6
  • 22
    • 41549143871 scopus 로고    scopus 로고
    • NFAT activation by membrane potential follows a calcium pathway distinct from other activity-related transcription factors in skeletal muscle cells
    • Valdes J.A., Gaggero E., Hidalgo J., Leal N., Jaimovich E., Carrasco M.A. NFAT activation by membrane potential follows a calcium pathway distinct from other activity-related transcription factors in skeletal muscle cells. Am J Physiol Cell Physiol Mar 2008, 294(3):C715-C725.
    • (2008) Am J Physiol Cell Physiol , vol.294 , Issue.3
    • Valdes, J.A.1    Gaggero, E.2    Hidalgo, J.3    Leal, N.4    Jaimovich, E.5    Carrasco, M.A.6
  • 26
    • 0037155771 scopus 로고    scopus 로고
    • Reduction of I(to) causes hypertrophy in neonatal rat ventricular myocytes
    • Kassiri Z., Zobel C., Nguyen T.T., Molkentin J.D., Backx P.H. Reduction of I(to) causes hypertrophy in neonatal rat ventricular myocytes. Circ Res Mar 22 2002, 90(5):578-585.
    • (2002) Circ Res , vol.90 , Issue.5 , pp. 578-585
    • Kassiri, Z.1    Zobel, C.2    Nguyen, T.T.3    Molkentin, J.D.4    Backx, P.H.5
  • 27
    • 0037195150 scopus 로고    scopus 로고
    • Prevention of hypertrophy by overexpression of Kv4.2 in cultured neonatal cardiomyocytes
    • Zobel C., Kassiri Z., Nguyen T.T., Meng Y., Backx P.H. Prevention of hypertrophy by overexpression of Kv4.2 in cultured neonatal cardiomyocytes. Circulation Oct 29 2002, 106(18):2385-2391.
    • (2002) Circulation , vol.106 , Issue.18 , pp. 2385-2391
    • Zobel, C.1    Kassiri, Z.2    Nguyen, T.T.3    Meng, Y.4    Backx, P.H.5
  • 28
    • 0032580202 scopus 로고    scopus 로고
    • Calcium oscillations increase the efficiency and specificity of gene expression
    • Dolmetsch R.E., Xu K., Lewis R.S. Calcium oscillations increase the efficiency and specificity of gene expression. Nature Apr 30 1998, 392(6679):933-936.
    • (1998) Nature , vol.392 , Issue.6679 , pp. 933-936
    • Dolmetsch, R.E.1    Xu, K.2    Lewis, R.S.3
  • 29
    • 20344400985 scopus 로고    scopus 로고
    • Bidirectional ventricular tachycardia and fibrillation elicited in a knock-in mouse model carrier of a mutation in the cardiac ryanodine receptor
    • Cerrone M., Colombi B., Santoro M., di Barletta M.R., Scelsi M., Villani L., et al. Bidirectional ventricular tachycardia and fibrillation elicited in a knock-in mouse model carrier of a mutation in the cardiac ryanodine receptor. Circ Res May 27 2005, 96(10):e77-e82.
    • (2005) Circ Res , vol.96 , Issue.10
    • Cerrone, M.1    Colombi, B.2    Santoro, M.3    di Barletta, M.R.4    Scelsi, M.5    Villani, L.6
  • 31
    • 33747072861 scopus 로고    scopus 로고
    • Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy
    • Kannankeril P.J., Mitchell B.M., Goonasekera S.A., Chelu M.G., Zhang W., Sood S., et al. Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy. Proc Natl Acad Sci USA Aug 8 2006, 103(32):12179-12184.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.32 , pp. 12179-12184
    • Kannankeril, P.J.1    Mitchell, B.M.2    Goonasekera, S.A.3    Chelu, M.G.4    Zhang, W.5    Sood, S.6
  • 32
    • 0037708928 scopus 로고    scopus 로고
    • FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death
    • Wehrens X.H., Lehnart S.E., Huang F., Vest J.A., Reiken S.R., Mohler P.J., et al. FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell Jun 27 2003, 113(7):829-840.
    • (2003) Cell , vol.113 , Issue.7 , pp. 829-840
    • Wehrens, X.H.1    Lehnart, S.E.2    Huang, F.3    Vest, J.A.4    Reiken, S.R.5    Mohler, P.J.6
  • 33
    • 2442667616 scopus 로고    scopus 로고
    • Molecular determinants of altered contractility in heart failure
    • Wehrens X.H., Marks A.R. Molecular determinants of altered contractility in heart failure. Ann Med 2004, 36(Suppl 1):70-80.
    • (2004) Ann Med , vol.36 , Issue.SUPPL. 1 , pp. 70-80
    • Wehrens, X.H.1    Marks, A.R.2
  • 34
    • 78649857349 scopus 로고    scopus 로고
    • Role of chronic ryanodine receptor phosphorylation in heart failure and beta-adrenergic receptor blockade in mice
    • Shan J., Betzenhauser M.J., Kushnir A., Reiken S., Meli A.C., Wronska A., et al. Role of chronic ryanodine receptor phosphorylation in heart failure and beta-adrenergic receptor blockade in mice. J Clin Invest Dec 1 2010, 120(12):4375-4387.
    • (2010) J Clin Invest , vol.120 , Issue.12 , pp. 4375-4387
    • Shan, J.1    Betzenhauser, M.J.2    Kushnir, A.3    Reiken, S.4    Meli, A.C.5    Wronska, A.6
  • 35
    • 78649835004 scopus 로고    scopus 로고
    • Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice
    • Shan J., Kushnir A., Betzenhauser M.J., Reiken S., Li J., Lehnart S.E., et al. Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice. J Clin Invest Dec 1 2010, 120(12):4388-4398.
    • (2010) J Clin Invest , vol.120 , Issue.12 , pp. 4388-4398
    • Shan, J.1    Kushnir, A.2    Betzenhauser, M.J.3    Reiken, S.4    Li, J.5    Lehnart, S.E.6
  • 36
    • 84889006323 scopus 로고    scopus 로고
    • 2+ control calcineurin-NFAT signaling and pathological hypertrophy in cardiac myocytes?
    • 2+ control calcineurin-NFAT signaling and pathological hypertrophy in cardiac myocytes?. Sci Signal 2008, 1(25):pe31.
    • (2008) Sci Signal , vol.1 , Issue.25
    • Houser, S.R.1    Molkentin, J.D.2
  • 38
    • 0035827719 scopus 로고    scopus 로고
    • Arrhythmogenesis and contractile dysfunction in heart failure: roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness
    • Pogwizd S.M., Schlotthauer K., Li L., Yuan W., Bers D.M. Arrhythmogenesis and contractile dysfunction in heart failure: roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. Circ Res Jun 8 2001, 88(11):1159-1167.
    • (2001) Circ Res , vol.88 , Issue.11 , pp. 1159-1167
    • Pogwizd, S.M.1    Schlotthauer, K.2    Li, L.3    Yuan, W.4    Bers, D.M.5
  • 39
    • 0032859611 scopus 로고    scopus 로고
    • Sodium/calcium exchange contributes to contraction and relaxation in failed human ventricular myocytes
    • Gaughan J.P., Furukawa S., Jeevanandam V., Hefner C.A., Kubo H., Margulies K.B., et al. Sodium/calcium exchange contributes to contraction and relaxation in failed human ventricular myocytes. Am J Physiol Aug 1999, 277(2 Pt 2):H714-H724.
    • (1999) Am J Physiol , vol.277 , Issue.2 PART 2
    • Gaughan, J.P.1    Furukawa, S.2    Jeevanandam, V.3    Hefner, C.A.4    Kubo, H.5    Margulies, K.B.6
  • 40
    • 0034644637 scopus 로고    scopus 로고
    • Enhanced Ca(2+)-activated Na(+)-Ca(2+) exchange activity in canine pacing-induced heart failure
    • Hobai I.A., O'Rourke B. Enhanced Ca(2+)-activated Na(+)-Ca(2+) exchange activity in canine pacing-induced heart failure. Circ Res Oct 13 2000, 87(8):690-698.
    • (2000) Circ Res , vol.87 , Issue.8 , pp. 690-698
    • Hobai, I.A.1    O'Rourke, B.2
  • 42
    • 77957053174 scopus 로고    scopus 로고
    • The IP3 receptor regulates cardiac hypertrophy in response to select stimuli
    • Nakayama H., Bodi I., Maillet M., DeSantiago J., Domeier T.L., Mikoshiba K., et al. The IP3 receptor regulates cardiac hypertrophy in response to select stimuli. Circ Res Sept 3 2010, 107(5):659-666.
    • (2010) Circ Res , vol.107 , Issue.5 , pp. 659-666
    • Nakayama, H.1    Bodi, I.2    Maillet, M.3    DeSantiago, J.4    Domeier, T.L.5    Mikoshiba, K.6
  • 44
    • 21844436786 scopus 로고    scopus 로고
    • 2+ signaling is abolished in atrial myocytes of inositol-1,4,5-trisphosphate(IP3)-receptor type 2-deficient mice
    • 2+ signaling is abolished in atrial myocytes of inositol-1,4,5-trisphosphate(IP3)-receptor type 2-deficient mice. Circ Res Jun 24 2005, 96(12):1274-1281.
    • (2005) Circ Res , vol.96 , Issue.12 , pp. 1274-1281
    • Li, X.1    Zima, A.V.2    Sheikh, F.3    Blatter, L.A.4    Chen, J.5
  • 46
    • 0034687814 scopus 로고    scopus 로고
    • Calsarcins, a novel family of sarcomeric calcineurin-binding proteins
    • Frey N., Richardson J.A., Olson E.N. Calsarcins, a novel family of sarcomeric calcineurin-binding proteins. Proc Natl AcadSci USA Dec 19 2000, 97(26):14632-14637.
    • (2000) Proc Natl AcadSci USA , vol.97 , Issue.26 , pp. 14632-14637
    • Frey, N.1    Richardson, J.A.2    Olson, E.N.3
  • 48
    • 62649117270 scopus 로고    scopus 로고
    • The pathological role of transient receptor potential channels in heart disease
    • Watanabe H., Murakami M., Ohba T., Ono K., Ito H. The pathological role of transient receptor potential channels in heart disease. Circ J Mar 2009, 73(3):419-427.
    • (2009) Circ J , vol.73 , Issue.3 , pp. 419-427
    • Watanabe, H.1    Murakami, M.2    Ohba, T.3    Ono, K.4    Ito, H.5
  • 49
    • 77951071535 scopus 로고    scopus 로고
    • TRPC channels are necessary mediators of pathologic cardiac hypertrophy
    • Wu X., Eder P., Chang B., Molkentin J.D. TRPC channels are necessary mediators of pathologic cardiac hypertrophy. Proc Natl Acad Sci USA Apr 13 2010, 107(15):7000-7005.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.15 , pp. 7000-7005
    • Wu, X.1    Eder, P.2    Chang, B.3    Molkentin, J.D.4
  • 52
    • 33646592211 scopus 로고    scopus 로고
    • Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation
    • Balijepalli R.C., Foell J.D., Hall D.D., Hell J.W., Kamp T.J. Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation. Proc Natl Acad Sci USA May 9 2006, 103(19):7500-7505.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.19 , pp. 7500-7505
    • Balijepalli, R.C.1    Foell, J.D.2    Hall, D.D.3    Hell, J.W.4    Kamp, T.J.5
  • 53
    • 61849143826 scopus 로고    scopus 로고
    • Caveolae, ion channels and cardiac arrhythmias
    • Balijepalli R.C., Kamp T.J. Caveolae, ion channels and cardiac arrhythmias. Prog Biophys Mol Biol Oct-Nov 2008, 98(2-3):149-160.
    • (2008) Prog Biophys Mol Biol , vol.98 , Issue.2-3 , pp. 149-160
    • Balijepalli, R.C.1    Kamp, T.J.2
  • 54
    • 0035877753 scopus 로고    scopus 로고
    • Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities
    • Galbiati F., Engelman J.A., Volonte D., Zhang X.L., Minetti C., Li M., et al. Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities. J Biol Chem Jun 15 2001, 276(24):21425-21433.
    • (2001) J Biol Chem , vol.276 , Issue.24 , pp. 21425-21433
    • Galbiati, F.1    Engelman, J.A.2    Volonte, D.3    Zhang, X.L.4    Minetti, C.5    Li, M.6
  • 57
    • 0028943777 scopus 로고
    • Association of protein kinase A and protein phosphatase 2B with a common anchoring protein
    • Coghlan V.M., Perrino B.A., Howard M., Langeberg L.K., Hicks J.B., Gallatin W.M., et al. Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. Science Jan 6 1995, 267(5194):108-111.
    • (1995) Science , vol.267 , Issue.5194 , pp. 108-111
    • Coghlan, V.M.1    Perrino, B.A.2    Howard, M.3    Langeberg, L.K.4    Hicks, J.B.5    Gallatin, W.M.6
  • 58
    • 33846982906 scopus 로고    scopus 로고
    • Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons
    • Hall D.D., Davare M.A., Shi M., Allen M.L., Weisenhaus M., McKnight G.S., et al. Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons. Biochemistry Feb 13 2007, 46(6):1635-1646.
    • (2007) Biochemistry , vol.46 , Issue.6 , pp. 1635-1646
    • Hall, D.D.1    Davare, M.A.2    Shi, M.3    Allen, M.L.4    Weisenhaus, M.5    McKnight, G.S.6
  • 59
    • 65249128530 scopus 로고    scopus 로고
    • 2+-ATPase isoform 4 antagonizes cardiac hypertrophy in association with calcineurin inhibition in rodents
    • 2+-ATPase isoform 4 antagonizes cardiac hypertrophy in association with calcineurin inhibition in rodents. J Clin Invest Apr 2009, 119(4):976-985.
    • (2009) J Clin Invest , vol.119 , Issue.4 , pp. 976-985
    • Wu, X.1    Chang, B.2    Blair, N.S.3    Sargent, M.4    York, A.J.5    Robbins, J.6
  • 60
    • 0033678548 scopus 로고    scopus 로고
    • Decoding calcium signals involved in cardiac growth and function
    • Frey N., McKinsey T.A., Olson E.N. Decoding calcium signals involved in cardiac growth and function. Nat Med Nov 2000, 6(11):1221-1227.
    • (2000) Nat Med , vol.6 , Issue.11 , pp. 1221-1227
    • Frey, N.1    McKinsey, T.A.2    Olson, E.N.3
  • 61
    • 0034685545 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy
    • 2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy. J Biol Chem May 19 2000, 275(20):15239-15245.
    • (2000) J Biol Chem , vol.275 , Issue.20 , pp. 15239-15245
    • Zhu, W.1    Zou, Y.2    Shiojima, I.3    Kudoh, S.4    Aikawa, R.5    Hayashi, D.6
  • 62
    • 0034463866 scopus 로고    scopus 로고
    • Chronic elevation of calmodulin in the ventricles of transgenic mice increases the autonomous activity of calmodulin-dependent protein kinase II, which regulates atrial natriuretic factor gene expression
    • Colomer J.M., Means A.R. Chronic elevation of calmodulin in the ventricles of transgenic mice increases the autonomous activity of calmodulin-dependent protein kinase II, which regulates atrial natriuretic factor gene expression. Mol Endocrinol Aug 2000, 14(8):1125-1136.
    • (2000) Mol Endocrinol , vol.14 , Issue.8 , pp. 1125-1136
    • Colomer, J.M.1    Means, A.R.2
  • 63
    • 60549085044 scopus 로고    scopus 로고
    • The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload
    • Backs J., Backs T., Neef S., Kreusser M.M., Lehmann L.H., Patrick D.M., et al. The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload. Proc Natl Acad Sci USA Feb 17 2009, 106(7):2342-2347.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.7 , pp. 2342-2347
    • Backs, J.1    Backs, T.2    Neef, S.3    Kreusser, M.M.4    Lehmann, L.H.5    Patrick, D.M.6
  • 64
    • 0037162697 scopus 로고    scopus 로고
    • Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy
    • Zhang C.L., McKinsey T.A., Chang S., Antos C.L., Hill J.A., Olson E.N. Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell Aug 23 2002, 110(4):479-488.
    • (2002) Cell , vol.110 , Issue.4 , pp. 479-488
    • Zhang, C.L.1    McKinsey, T.A.2    Chang, S.3    Antos, C.L.4    Hill, J.A.5    Olson, E.N.6
  • 65
    • 33745812011 scopus 로고    scopus 로고
    • CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy
    • Backs J., Song K., Bezprozvannaya S., Chang S., Olson E.N. CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy. J Clin Invest Jul 2006, 116(7):1853-1864.
    • (2006) J Clin Invest , vol.116 , Issue.7 , pp. 1853-1864
    • Backs, J.1    Song, K.2    Bezprozvannaya, S.3    Chang, S.4    Olson, E.N.5
  • 66
    • 58149280497 scopus 로고    scopus 로고
    • 2+ in cardiac myocytes
    • 2+ in cardiac myocytes. Biophys J Nov 15 2008, 95(10):4597-4612.
    • (2008) Biophys J , vol.95 , Issue.10 , pp. 4597-4612
    • Saucerman, J.J.1    Bers, D.M.2
  • 68
    • 79251564794 scopus 로고    scopus 로고
    • TRPC channels as effectors of cardiac hypertrophy
    • Eder P., Molkentin J.D. TRPC channels as effectors of cardiac hypertrophy. Circ Res Jan 21 2011, 108(2):265-272.
    • (2011) Circ Res , vol.108 , Issue.2 , pp. 265-272
    • Eder, P.1    Molkentin, J.D.2
  • 69
    • 77952569728 scopus 로고    scopus 로고
    • Orai1 and Stim1 regulate normal and hypertrophic growth in cardiomyocytes
    • Voelkers M., Salz M., Herzog N., Frank D., Dolatabadi N., Frey N., et al. Orai1 and Stim1 regulate normal and hypertrophic growth in cardiomyocytes. J Mol Cell Cardiol Jun 2010, 48(6):1329-1334.
    • (2010) J Mol Cell Cardiol , vol.48 , Issue.6 , pp. 1329-1334
    • Voelkers, M.1    Salz, M.2    Herzog, N.3    Frank, D.4    Dolatabadi, N.5    Frey, N.6
  • 70
    • 0032480008 scopus 로고    scopus 로고
    • A novel capacitative calcium entry channel expressed in excitable cells
    • Philipp S., Hambrecht J., Braslavski L., Schroth G., Freichel M., Murakami M., et al. A novel capacitative calcium entry channel expressed in excitable cells. EMBO J Aug 3 1998, 17(15):4274-4282.
    • (1998) EMBO J , vol.17 , Issue.15 , pp. 4274-4282
    • Philipp, S.1    Hambrecht, J.2    Braslavski, L.3    Schroth, G.4    Freichel, M.5    Murakami, M.6
  • 72
    • 79959773002 scopus 로고    scopus 로고
    • Contribution of TRPC1 and Orai1 to Ca(2+) entry activated by store depletion
    • Cheng K.T., Ong H.L., Liu X., Ambudkar I.S. Contribution of TRPC1 and Orai1 to Ca(2+) entry activated by store depletion. Adv Exp Med Biol 2011, 704:435-449.
    • (2011) Adv Exp Med Biol , vol.704 , pp. 435-449
    • Cheng, K.T.1    Ong, H.L.2    Liu, X.3    Ambudkar, I.S.4
  • 73
    • 77954214838 scopus 로고    scopus 로고
    • Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart
    • Kinoshita H., Kuwahara K., Nishida M., Jian Z., Rong X., Kiyonaka S., et al. Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart. Circ Res Jun 25 2010, 106(12):1849-1860.
    • (2010) Circ Res , vol.106 , Issue.12 , pp. 1849-1860
    • Kinoshita, H.1    Kuwahara, K.2    Nishida, M.3    Jian, Z.4    Rong, X.5    Kiyonaka, S.6
  • 74
    • 72449170101 scopus 로고    scopus 로고
    • TRPC1 channels are critical for hypertrophic signaling in the heart
    • Seth M., Zhang Z.S., Mao L., Graham V., Burch J., Stiber J., et al. TRPC1 channels are critical for hypertrophic signaling in the heart. Circ Res Nov 6 2009, 105(10):1023-1030.
    • (2009) Circ Res , vol.105 , Issue.10 , pp. 1023-1030
    • Seth, M.1    Zhang, Z.S.2    Mao, L.3    Graham, V.4    Burch, J.5    Stiber, J.6
  • 75
    • 33845597014 scopus 로고    scopus 로고
    • Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling
    • Bush E.W., Hood D.B., Papst P.J., Chapo J.A., Minobe W., Bristow M.R., et al. Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling. J Biol Chem Nov 3 2006, 281(44):33487-33496.
    • (2006) J Biol Chem , vol.281 , Issue.44 , pp. 33487-33496
    • Bush, E.W.1    Hood, D.B.2    Papst, P.J.3    Chapo, J.A.4    Minobe, W.5    Bristow, M.R.6
  • 76
    • 33845317604 scopus 로고    scopus 로고
    • TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling
    • Kuwahara K., Wang Y., McAnally J., Richardson J.A., Bassel-Duby R., Hill J.A., et al. TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling. J Clin Invest Dec 2006, 116(12):3114-3126.
    • (2006) J Clin Invest , vol.116 , Issue.12 , pp. 3114-3126
    • Kuwahara, K.1    Wang, Y.2    McAnally, J.3    Richardson, J.A.4    Bassel-Duby, R.5    Hill, J.A.6
  • 78
    • 65249173997 scopus 로고    scopus 로고
    • Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound
    • Kiyonaka S., Kato K., Nishida M., Mio K., Numaga T., Sawaguchi Y., et al. Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound. Proc Natl Acad Sci USA Mar 31 2009, 106(13):5400-5405.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.13 , pp. 5400-5405
    • Kiyonaka, S.1    Kato, K.2    Nishida, M.3    Mio, K.4    Numaga, T.5    Sawaguchi, Y.6
  • 79
    • 33749338744 scopus 로고    scopus 로고
    • Calcineurin-dependent cardiomyopathy is activated by TRPC in the adult mouse heart
    • Nakayama H., Wilkin B.J., Bodi I., Molkentin J.D. Calcineurin-dependent cardiomyopathy is activated by TRPC in the adult mouse heart. FASEB J Aug 2006, 20(10):1660-1670.
    • (2006) FASEB J , vol.20 , Issue.10 , pp. 1660-1670
    • Nakayama, H.1    Wilkin, B.J.2    Bodi, I.3    Molkentin, J.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.