메뉴 건너뛰기




Volumn 180, Issue 2, 2012, Pages 494-504

HIF-2α expression is suppressed in SCLC cells, which survive in moderate and severe hypoxia when HIF-1α is repressed

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PRIMER DNA; PROTEIN BNIP3;

EID: 84855998771     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.10.014     Document Type: Article
Times cited : (18)

References (47)
  • 1
    • 77954347979 scopus 로고    scopus 로고
    • Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • Group EGW
    • M. Sørensen, M. Pijls-Johannesma, E. Felip Group EGW Small-cell lung cancer: eSMO Clinical Practice Guidelines for diagnosis, treatment and follow-up Ann Oncol 21 Suppl 5 2010 v120 v125
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 5
    • Sørensen, M.1    Pijls-Johannesma, M.2    Felip, E.3
  • 2
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • J.M. Brown, W.R. Wilson Exploiting tumour hypoxia in cancer treatment Nat Rev Cancer 4 2004 437 447
    • (2004) Nat Rev Cancer , vol.4 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 3
    • 40949088476 scopus 로고    scopus 로고
    • Biology of hypoxia-inducible factor-2alpha in development and disease
    • S.A. Patel, M.C. Simon Biology of hypoxia-inducible factor-2alpha in development and disease Cell Death Differ 15 2008 628 634
    • (2008) Cell Death Differ , vol.15 , pp. 628-634
    • Patel, S.A.1    Simon, M.C.2
  • 5
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxiaa key regulatory factor in tumour growth
    • A.L. Harris Hypoxiaa key regulatory factor in tumour growth Nat Rev Cancer 2 2002 38 47
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 6
    • 0345491599 scopus 로고    scopus 로고
    • Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation
    • C.J. Hu, L.Y. Wang, L.A. Chodosh, B. Keith, M.C. Simon Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation Mol Cell Biol 23 2003 9361 9374
    • (2003) Mol Cell Biol , vol.23 , pp. 9361-9374
    • Hu, C.J.1    Wang, L.Y.2    Chodosh, L.A.3    Keith, B.4    Simon, M.C.5
  • 7
    • 0035884701 scopus 로고    scopus 로고
    • HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
    • H.M. Sowter, P.J. Ratcliffe, P. Watson, A.H. Greenberg, A.L. Harris HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors Cancer Res 61 2001 6669 6673
    • (2001) Cancer Res , vol.61 , pp. 6669-6673
    • Sowter, H.M.1    Ratcliffe, P.J.2    Watson, P.3    Greenberg, A.H.4    Harris, A.L.5
  • 9
    • 2442544693 scopus 로고    scopus 로고
    • Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: Implication of natural antisense HIF-1alpha
    • T. Uchida, F. Rossignol, M.A. Matthay, R. Mounier, S. Couette, E. Clottes, C. Clerici Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha J Biol Chem 279 2004 14871 14878
    • (2004) J Biol Chem , vol.279 , pp. 14871-14878
    • Uchida, T.1    Rossignol, F.2    Matthay, M.A.3    Mounier, R.4    Couette, S.5    Clottes, E.6    Clerici, C.7
  • 10
    • 79959215471 scopus 로고    scopus 로고
    • Differential hypoxic regulation of hypoxia-inducible factors 1alpha and 2alpha
    • Q. Lin, X. Cong, Z. Yun Differential hypoxic regulation of hypoxia-inducible factors 1alpha and 2alpha Mol Cancer Res 9 2011 757 765
    • (2011) Mol Cancer Res , vol.9 , pp. 757-765
    • Lin, Q.1    Cong, X.2    Yun, Z.3
  • 12
    • 0029982422 scopus 로고    scopus 로고
    • Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1 alpha
    • R.H. Wenger, A. Rolfs, H.H. Marti, J.L. Guenet, M. Gassmann Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1 alpha Biochem Biophys Res Commun 223 1996 54 59
    • (1996) Biochem Biophys Res Commun , vol.223 , pp. 54-59
    • Wenger, R.H.1    Rolfs, A.2    Marti, H.H.3    Guenet, J.L.4    Gassmann, M.5
  • 13
    • 0031971047 scopus 로고    scopus 로고
    • Expression of ARNT ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse
    • S. Jain, E. Maltepe, M.M. Lu, C. Simon, C.A. Bradfield Expression of ARNT ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse Mech Dev 73 1998 117 123
    • (1998) Mech Dev , vol.73 , pp. 117-123
    • Jain, S.1    Maltepe, E.2    Lu, M.M.3    Simon, C.4    Bradfield, C.A.5
  • 15
    • 0033258421 scopus 로고    scopus 로고
    • Hypoxia upregulates activity and expression of the glucose transporter GLUT1 in alveolar epithelial cells
    • A. Ouiddir, C. Planes, I. Fernandes, A. VanHesse, C. Clerici Hypoxia upregulates activity and expression of the glucose transporter GLUT1 in alveolar epithelial cells Am J Respir Cell Mol Biol 21 1999 710 718
    • (1999) Am J Respir Cell Mol Biol , vol.21 , pp. 710-718
    • Ouiddir, A.1    Planes, C.2    Fernandes, I.3    Vanhesse, A.4    Clerici, C.5
  • 16
    • 0035142809 scopus 로고    scopus 로고
    • Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: A possible signal for vessel development
    • Y.M. Lee, C.H. Jeong, S.Y. Koo, M.J. Son, H.S. Song, S.K. Bae, J.A. Raleigh, H.Y. Chung, M.A. Yoo, K.W. Kim Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: a possible signal for vessel development Dev Dyn 220 2001 175 186
    • (2001) Dev Dyn , vol.220 , pp. 175-186
    • Lee, Y.M.1    Jeong, C.H.2    Koo, S.Y.3    Son, M.J.4    Song, H.S.5    Bae, S.K.6    Raleigh, J.A.7    Chung, H.Y.8    Yoo, M.A.9    Kim, K.W.10
  • 19
    • 57749086980 scopus 로고    scopus 로고
    • HIF1alpha is essential for normal intrauterine differentiation of alveolar epithelium and surfactant production in the newborn lung of mice
    • Y. Saini, J.R. Harkema, J.J. LaPres HIF1alpha is essential for normal intrauterine differentiation of alveolar epithelium and surfactant production in the newborn lung of mice J Biol Chem 283 2008 33650 33657
    • (2008) J Biol Chem , vol.283 , pp. 33650-33657
    • Saini, Y.1    Harkema, J.R.2    Lapres, J.J.3
  • 21
    • 0031000736 scopus 로고    scopus 로고
    • A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development
    • M. Ema, S. Taya, N. Yokotani, K. Sogawa, Y. Matsuda, Y. Fujii-Kuriyama A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development Proc Natl Acad Sci U S A 94 1997 4273 4278
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 4273-4278
    • Ema, M.1    Taya, S.2    Yokotani, N.3    Sogawa, K.4    Matsuda, Y.5    Fujii-Kuriyama, Y.6
  • 22
    • 33846199233 scopus 로고    scopus 로고
    • Hypoxia-inducible factors: Central regulators of the tumor phenotype
    • J.D. Gordan, M.C. Simon Hypoxia-inducible factors: central regulators of the tumor phenotype Curr Opin Genet Dev 17 2007 71 77
    • (2007) Curr Opin Genet Dev , vol.17 , pp. 71-77
    • Gordan, J.D.1    Simon, M.C.2
  • 23
    • 78349283042 scopus 로고    scopus 로고
    • The HIF-2alpha-driven pseudo-hypoxic phenotype in tumor aggressiveness, differentiation, and vascularization
    • A. Pietras, A.S. Johnsson, S. Phlman The HIF-2alpha-driven pseudo-hypoxic phenotype in tumor aggressiveness, differentiation, and vascularization Curr Top Microbiol Immunol 345 2010 1 20
    • (2010) Curr Top Microbiol Immunol , vol.345 , pp. 1-20
    • Pietras, A.1    Johnsson, A.S.2    Phlman, S.3
  • 24
    • 67049165796 scopus 로고    scopus 로고
    • Upregulation of hypoxia-inducible factor-1alpha mRNA and its clinical significance in non-small cell lung cancer
    • T. Yohena, I. Yoshino, T. Takenaka, T. Kameyama, T. Ohba, Y. Kuniyoshi, Y. Maehara Upregulation of hypoxia-inducible factor-1alpha mRNA and its clinical significance in non-small cell lung cancer J Thorac Oncol 4 2009 284 290
    • (2009) J Thorac Oncol , vol.4 , pp. 284-290
    • Yohena, T.1    Yoshino, I.2    Takenaka, T.3    Kameyama, T.4    Ohba, T.5    Kuniyoshi, Y.6    Maehara, Y.7
  • 25
    • 0346256583 scopus 로고    scopus 로고
    • Differential expression of hypoxia inducible factor-1 alpha and tumor cell proliferation between squamous cell carcinomas and adenocarcinomas among operable non-small cell lung carcinomas
    • C.H. Lee, M.K. Lee, C.D. Kang, Y.D. Kim, D.Y. Park, J.Y. Kim, M.Y. Sol, K.S. Suh Differential expression of hypoxia inducible factor-1 alpha and tumor cell proliferation between squamous cell carcinomas and adenocarcinomas among operable non-small cell lung carcinomas J Korean Med Sci 18 2003 196 203
    • (2003) J Korean Med Sci , vol.18 , pp. 196-203
    • Lee, C.H.1    Lee, M.K.2    Kang, C.D.3    Kim, Y.D.4    Park, D.Y.5    Kim, J.Y.6    Sol, M.Y.7    Suh, K.S.8
  • 26
    • 0035860147 scopus 로고    scopus 로고
    • Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival
    • A. Giatromanolaki, M.I. Koukourakis, E. Sivridis, H. Turley, K. Talks, F. Pezzella, K.C. Gatter, A.L. Harris Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival Br J Cancer 85 2001 881 890
    • (2001) Br J Cancer , vol.85 , pp. 881-890
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Sivridis, E.3    Turley, H.4    Talks, K.5    Pezzella, F.6    Gatter, K.C.7    Harris, A.L.8
  • 28
    • 72949100977 scopus 로고    scopus 로고
    • Prognostic significance of hypoxia-inducible factor-1alpha TWIST1 and Snail expression in resectable non-small cell lung cancer
    • J.J. Hung, M.H. Yang, H.S. Hsu, W.H. Hsu, J.S. Liu, K.J. Wu Prognostic significance of hypoxia-inducible factor-1alpha TWIST1 and Snail expression in resectable non-small cell lung cancer Thorax 64 2009 1082 1089
    • (2009) Thorax , vol.64 , pp. 1082-1089
    • Hung, J.J.1    Yang, M.H.2    Hsu, H.S.3    Hsu, W.H.4    Liu, J.S.5    Wu, K.J.6
  • 30
    • 3042816190 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 alpha in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways
    • D.E. Swinson, J.L. Jones, G. Cox, D. Richardson, A.L. Harris, K.J. O'Byrne Hypoxia-inducible factor-1 alpha in non small cell lung cancer: relation to growth factor, protease and apoptosis pathways Int J Cancer 111 2004 43 50
    • (2004) Int J Cancer , vol.111 , pp. 43-50
    • Swinson, D.E.1    Jones, J.L.2    Cox, G.3    Richardson, D.4    Harris, A.L.5    O'Byrne, K.J.6
  • 34
    • 22044450616 scopus 로고    scopus 로고
    • Phenotypic persistence after reoxygenation of hypoxic neuroblastoma cells
    • L. Holmquist, A. Jgi, S. Phlman Phenotypic persistence after reoxygenation of hypoxic neuroblastoma cells Int J Cancer 116 2005 218 225
    • (2005) Int J Cancer , vol.116 , pp. 218-225
    • Holmquist, L.1    Jgi, A.2    Phlman, S.3
  • 36
    • 4544361863 scopus 로고    scopus 로고
    • Induction of ID2 expression by hypoxia-inducible factor-1: A role in dedifferentiation of hypoxic neuroblastoma cells
    • T. Lfstedt, A. Jgi, M. Sigvardsson, K. Gradin, L. Poellinger, S. Phlman, H. Axelson Induction of ID2 expression by hypoxia-inducible factor-1: a role in dedifferentiation of hypoxic neuroblastoma cells J Biol Chem 279 2004 39223 39231
    • (2004) J Biol Chem , vol.279 , pp. 39223-39231
    • Lfstedt, T.1    Jgi, A.2    Sigvardsson, M.3    Gradin, K.4    Poellinger, L.5    Phlman, S.6    Axelson, H.7
  • 37
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • J. Vandesompele, K. De Preter, F. Pattyn, B. Poppe, N. Van Roy, A. De Paepe, F. Speleman Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Genome Biol 3 2002 RESEARCH0034
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 38
    • 0020071993 scopus 로고
    • Establishment and characterization of two neoplastic cell lines (U-1285 and U-1568) derived from small cell carcinoma of the lung
    • J. Bergh, E. Larsson, L. Zech, K. Nilsson Establishment and characterization of two neoplastic cell lines (U-1285 and U-1568) derived from small cell carcinoma of the lung Acta Pathol Microbiol Immunol Scand A 90 1982 149 158
    • (1982) Acta Pathol Microbiol Immunol Scand A , vol.90 , pp. 149-158
    • Bergh, J.1    Larsson, E.2    Zech, L.3    Nilsson, K.4
  • 39
    • 0035925098 scopus 로고    scopus 로고
    • Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
    • M. Hckel, P. Vaupel Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects J Natl Cancer Inst 93 2001 266 276
    • (2001) J Natl Cancer Inst , vol.93 , pp. 266-276
    • Hckel, M.1    Vaupel, P.2
  • 40
    • 34347227058 scopus 로고    scopus 로고
    • Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1
    • G.L. Semenza Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1 Biochem J 405 2007 1s 9s
    • (2007) Biochem J , vol.405
    • Semenza, G.L.1
  • 44
    • 77956619564 scopus 로고    scopus 로고
    • Cell of origin of lung cancer
    • K.D. Sutherland, A. Berns Cell of origin of lung cancer Mol Oncol 4 2008 397 403
    • (2008) Mol Oncol , vol.4 , pp. 397-403
    • Sutherland, K.D.1    Berns, A.2
  • 45
    • 79958761641 scopus 로고    scopus 로고
    • Cell of origin of small cell lung cancer: Inactivation of Trp53 and rb1 in distinct cell types of adult mouse lung
    • K.D. Sutherland, N. Proost, I. Brouns, D. Adriaensen, J.Y. Song, A. Berns Cell of origin of small cell lung cancer: inactivation of Trp53 and rb1 in distinct cell types of adult mouse lung Cancer Cell 19 2011 754 764
    • (2011) Cancer Cell , vol.19 , pp. 754-764
    • Sutherland, K.D.1    Proost, N.2    Brouns, I.3    Adriaensen, D.4    Song, J.Y.5    Berns, A.6
  • 46
    • 76549126430 scopus 로고    scopus 로고
    • Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung
    • J.L. McQualter, K. Yuen, B. Williams, I. Bertoncello Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung Proc Natl Acad Sci U S A 107 2010 1414 1419
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 1414-1419
    • McQualter, J.L.1    Yuen, K.2    Williams, B.3    Bertoncello, I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.