TGF-β promotes proliferation of thyroid epithelial cells in IFN-γ -/- mice by down-regulation of p21 and p27 via AKT pathway

American Journal of Pathology

Volumn 180, Issue 2, 2012, Pages 650-660

  Fang, Yujiang ^a   Yu, Shiguang ^a   Braley Mullen, Helen ^a  

^a University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D; CYCLINE; GAMMA INTERFERON; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN P18; PROTEIN P21; PROTEIN P27; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM CELL; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; THYROID CELL; UPREGULATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DOWN-REGULATION; EPITHELIAL CELLS; INTERFERON-GAMMA; MICE; MICE, INBRED NOD; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; THYROID GLAND; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84855992224     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.10.009     Document Type: Article

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