Transgenic epression of TGF-β on thyrocytes inhibits development of spontaneous autoimmune thyroiditis and increases regulatory T cells in thyroids of NOD.H-2h4 mice

Journal of Immunology

Volumn 184, Issue 9, 2010, Pages 5352-5359

  Yu, Shiguang ^a,b,c   Fang, Yujiang ^a,b   Sharp, Gordon C ^a   Braley Mullen, Helen ^a,b  

^a University of Missouri   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c ARKANSAS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; THYROGLOBULIN; THYROGLOBULIN ANTIBODY; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; GROWTH INHIBITOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DETECTION; ARTICLE; AUTOIMMUNE THYROIDITIS; CD25+ T LYMPHOCYTE; CELL HYPERPLASIA; CELL MIGRATION; CELL PROLIFERATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FEMALE; FIBROSIS; FLOW CYTOMETRY; GENE EXPRESSION; GENE OVEREXPRESSION; IMMUNOHISTOCHEMISTRY; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM; SPONTANEOUS AUTOIMMUNE THYROIDITIS; T CELL DEPLETION; THYROID GLAND; TRANSGENIC MOUSE; TRANSGENICS; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL DIFFERENTIATION; COMPARATIVE STUDY; GENETICS; IMMUNOLOGY; LYMPHOCYTE DEPLETION; METABOLISM; MOUSE MUTANT; NONOBESE DIABETIC MOUSE; PATHOLOGY; RAT;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; EPITHELIAL CELLS; FEMALE; GROWTH INHIBITORS; LYMPHOCYTE DEPLETION; MALE; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; MICE, TRANSGENIC; RATS; T-LYMPHOCYTES, REGULATORY; THYROID GLAND; THYROIDITIS, AUTOIMMUNE; TRANSFORMING GROWTH FACTOR BETA;

EID: 77954505672     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903620     Document Type: Article

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