-
2
-
-
80052408057
-
Molecular determinants within N terminus of Orai3 protein that control channel activation and gating
-
Bergsmann J, Derler I, Muik M, Frischauf I, Fahrner M, Plooheimer P, Schwarzinger C, Gruber HJ, Groschner K & Romanin C (2011). Molecular determinants within N terminus of Orai3 protein that control channel activation and gating. J Biol Chem 286, 31565-31575.
-
(2011)
J Biol Chem
, vol.286
, pp. 31565-31575
-
-
Bergsmann, J.1
Derler, I.2
Muik, M.3
Frischauf, I.4
Fahrner, M.5
Plooheimer, P.6
Schwarzinger, C.7
Gruber, H.J.8
Groschner, K.9
Romanin, C.10
-
3
-
-
0025350112
-
Calcium oscillations
-
Berridge MJ (1990). Calcium oscillations. J Biol Chem 265, 9583-9586.
-
(1990)
J Biol Chem
, vol.265
, pp. 9583-9586
-
-
Berridge, M.J.1
-
4
-
-
0024219844
-
Cytosolic calcium oscillators
-
Berridge MJ & Galione A (1988). Cytosolic calcium oscillators. FASEB J 2, 3074-3082.
-
(1988)
FASEB J
, vol.2
, pp. 3074-3082
-
-
Berridge, M.J.1
Galione, A.2
-
5
-
-
0036829060
-
Inhibition of the type 1 inositol 1,4,5-trisphosphate receptor by 2-aminoethoxydiphenylborate
-
Bilmen JG & Michelangeli F (2002). Inhibition of the type 1 inositol 1, 4, 5-trisphosphate receptor by 2-aminoethoxydiphenylborate. Cell Signal 14, 955-960.
-
(2002)
Cell Signal
, vol.14
, pp. 955-960
-
-
Bilmen, J.G.1
Michelangeli, F.2
-
6
-
-
77953654218
-
Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling
-
Bogeski I, Kummerow C, Al-Ansary D, Schwarz EC, Koehler R, Kozai D, Takahashi N, Peinelt C, Griesemer D, Bozem M, Mori Y, Hoth M & Niemeyer BA (2010). Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling. Sci Signal 3, ra24.
-
(2010)
Sci Signal
, vol.3
-
-
Bogeski, I.1
Kummerow, C.2
Al-Ansary, D.3
Schwarz, E.C.4
Koehler, R.5
Kozai, D.6
Takahashi, N.7
Peinelt, C.8
Griesemer, D.9
Bozem, M.10
Mori, Y.11
Hoth, M.12
Niemeyer, B.A.13
-
7
-
-
0030019847
-
Extracellular calcium concentration controls the frequency of intracellular calcium spiking independently of inositol 1,4,5-trisphosphate production in HeLa cells
-
Bootman MD, Young KW, Young JM, Moreton RB & Berridge MJ (1996). Extracellular calcium concentration controls the frequency of intracellular calcium spiking independently of inositol 1, 4, 5-trisphosphate production in HeLa cells. Biochem J 314, 347-354.
-
(1996)
Biochem J
, vol.314
, pp. 347-354
-
-
Bootman, M.D.1
Young, K.W.2
Young, J.M.3
Moreton, R.B.4
Berridge, M.J.5
-
8
-
-
61949190323
-
Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation
-
Braun A, Varga-Szabo D, Kleinschnitz C, Pleines I, Bender M, Austinat M, Bosl M, Stoll G & Nieswandt B (2009). Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation. Blood 113, 2056-2063.
-
(2009)
Blood
, vol.113
, pp. 2056-2063
-
-
Braun, A.1
Varga-Szabo, D.2
Kleinschnitz, C.3
Pleines, I.4
Bender, M.5
Austinat, M.6
Bosl, M.7
Stoll, G.8
Nieswandt, B.9
-
9
-
-
34247193635
-
2+ channel subunit, orai
-
2+ channel subunit, orai. J Mol Biol 368, 1284-1291.
-
(2007)
J Mol Biol
, vol.368
, pp. 1284-1291
-
-
Cai, X.1
-
10
-
-
2642568616
-
2-Aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3
-
Chung MK, Lee H, Mizuno A, Suzuki M & Caterina MJ (2004). 2-Aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3. J Neurosci 24, 5177-5182.
-
(2004)
J Neurosci
, vol.24
, pp. 5177-5182
-
-
Chung, M.K.1
Lee, H.2
Mizuno, A.3
Suzuki, M.4
Caterina, M.J.5
-
12
-
-
50349103128
-
Complex actions of 2-aminoethyldiphenyl borate on store-operated calcium entry
-
DeHaven WI, Smyth JT, Boyles RR, Bird GS & Putney JW Jr (2008). Complex actions of 2-aminoethyldiphenyl borate on store-operated calcium entry. J Biol Chem 283, 19265-19273.
-
(2008)
J Biol Chem
, vol.283
, pp. 19265-19273
-
-
DeHaven, W.I.1
Smyth, J.T.2
Boyles, R.R.3
Bird, G.S.4
Putney Jr, J.W.5
-
13
-
-
34347342283
-
Calcium inhibition and calcium potentiation of orai1, orai2, and orai3 calcium release-activated calcium channels
-
DeHaven WI, Smyth JT, Boyles RR & Putney JW Jr (2007). Calcium inhibition and calcium potentiation of orai1, orai2, and orai3 calcium release-activated calcium channels. J Biol Chem 282, 17548-17556.
-
(2007)
J Biol Chem
, vol.282
, pp. 17548-17556
-
-
DeHaven, W.I.1
Smyth, J.T.2
Boyles, R.R.3
Putney Jr, J.W.4
-
14
-
-
0032580202
-
Calcium oscillations increase the efficiency and specificity of gene expression
-
Dolmetsch RE, Xu KL & Lewis RS (1998). Calcium oscillations increase the efficiency and specificity of gene expression. Nature 392, 933-936.
-
(1998)
Nature
, vol.392
, pp. 933-936
-
-
Dolmetsch, R.E.1
Xu, K.L.2
Lewis, R.S.3
-
15
-
-
78649683967
-
Down-regulation of Orai3 arrests cell-cycle progression and induces apoptosis in breast cancer cells but not in normal breast epithelial cells
-
Faouzi M, Hague F, Potier M, Ahidouch A, Sevestre H & Ouadid-Ahidouch H (2011). Down-regulation of Orai3 arrests cell-cycle progression and induces apoptosis in breast cancer cells but not in normal breast epithelial cells. J Cell Physiol 226, 542-551.
-
(2011)
J Cell Physiol
, vol.226
, pp. 542-551
-
-
Faouzi, M.1
Hague, F.2
Potier, M.3
Ahidouch, A.4
Sevestre, H.5
Ouadid-Ahidouch, H.6
-
16
-
-
70349116421
-
2+ entry in the immune system and beyond
-
2+ entry in the immune system and beyond. Immunol Rev 231, 189-209.
-
(2009)
Immunol Rev
, vol.231
, pp. 189-209
-
-
Feske, S.1
-
17
-
-
33646576875
-
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
-
Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel SH, Tanasa B, Hogan PG, Lewis RS, Daly M & Rao A (2006). A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441, 179-185.
-
(2006)
Nature
, vol.441
, pp. 179-185
-
-
Feske, S.1
Gwack, Y.2
Prakriya, M.3
Srikanth, S.4
Puppel, S.H.5
Tanasa, B.6
Hogan, P.G.7
Lewis, R.S.8
Daly, M.9
Rao, A.10
-
18
-
-
69249152563
-
Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant
-
Frischauf I, Muik M, Derler I, Bergsmann J, Fahrner M, Schindl R, Groschner K & Romanin C (2009). Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant. J Biol Chem 284, 21696-21706.
-
(2009)
J Biol Chem
, vol.284
, pp. 21696-21706
-
-
Frischauf, I.1
Muik, M.2
Derler, I.3
Bergsmann, J.4
Fahrner, M.5
Schindl, R.6
Groschner, K.7
Romanin, C.8
-
19
-
-
0035281595
-
2+ channels in liver cells, and acts through a mechanism which does not involve inositol trisphosphate receptors
-
2+ channels in liver cells, and acts through a mechanism which does not involve inositol trisphosphate receptors. Biochem J 354, 285-290.
-
(2001)
Biochem J
, vol.354
, pp. 285-290
-
-
Gregory, R.B.1
Rychkov, G.2
Barritt, G.J.3
-
20
-
-
34447254660
-
Murine ORAI2 splice variants form functional CRAC channels
-
Gross SA, Wissenbach U, Philipp SE, Freichel M, Cavalie A & Flockerzi V (2007). Murine ORAI2 splice variants form functional CRAC channels. J Biol Chem 282, 19375-19384.
-
(2007)
J Biol Chem
, vol.282
, pp. 19375-19384
-
-
Gross, S.A.1
Wissenbach, U.2
Philipp, S.E.3
Freichel, M.4
Cavalie, A.5
Flockerzi, V.6
-
21
-
-
34247339504
-
Biochemical and functional characterization of Orai proteins
-
Gwack Y, Srikanth S, Feske S, Cruz-Guilloty F, Oh-Hora M, Neems DS, Hogan PG & Rao A (2007). Biochemical and functional characterization of Orai proteins. J Biol Chem 282, 16232-16243.
-
(2007)
J Biol Chem
, vol.282
, pp. 16232-16243
-
-
Gwack, Y.1
Srikanth, S.2
Feske, S.3
Cruz-Guilloty, F.4
Oh-Hora, M.5
Neems, D.S.6
Hogan, P.G.7
Rao, A.8
-
22
-
-
50249165416
-
Hair loss and defective T- and B-cell function in mice lacking ORAI1
-
Gwack Y, Srikanth S, Oh-Hora M, Hogan PG, Lamperti ED, Yamashita M, Gelinas C, Neems DS, Sasaki Y, Feske S, Prakriya M, Rajewsky K & Rao A (2008). Hair loss and defective T- and B-cell function in mice lacking ORAI1. Mol Cell Biol 28, 5209-5222.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5209-5222
-
-
Gwack, Y.1
Srikanth, S.2
Oh-Hora, M.3
Hogan, P.G.4
Lamperti, E.D.5
Yamashita, M.6
Gelinas, C.7
Neems, D.S.8
Sasaki, Y.9
Feske, S.10
Prakriya, M.11
Rajewsky, K.12
Rao, A.13
-
23
-
-
0029143569
-
Decoding of cytosolic calcium oscillations in the mitochondria
-
Hajnoczky G, Robb-Gaspers LD, Seitz MB & Thomas AP (1995). Decoding of cytosolic calcium oscillations in the mitochondria. Cell 82, 415-424.
-
(1995)
Cell
, vol.82
, pp. 415-424
-
-
Hajnoczky, G.1
Robb-Gaspers, L.D.2
Seitz, M.B.3
Thomas, A.P.4
-
24
-
-
77950377028
-
Molecular basis of calcium signaling in lymphocytes: STIM and ORAI
-
Hogan PG, Lewis RS & Rao A (2010). Molecular basis of calcium signaling in lymphocytes: STIM and ORAI. Annu Rev Immunol 28, 491-533.
-
(2010)
Annu Rev Immunol
, vol.28
, pp. 491-533
-
-
Hogan, P.G.1
Lewis, R.S.2
Rao, A.3
-
25
-
-
0026594980
-
Depletion of intracellular calcium stores activates a calcium current in mast cells
-
Hoth M & Penner R (1992). Depletion of intracellular calcium stores activates a calcium current in mast cells. Nature 355, 353-356.
-
(1992)
Nature
, vol.355
, pp. 353-356
-
-
Hoth, M.1
Penner, R.2
-
26
-
-
0027175061
-
Calcium release-activated calcium current in rat mast cells
-
Hoth M & Penner R (1993). Calcium release-activated calcium current in rat mast cells. J Physiol 465, 359-386.
-
(1993)
J Physiol
, vol.465
, pp. 359-386
-
-
Hoth, M.1
Penner, R.2
-
27
-
-
4143090688
-
2-Aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3
-
Hu HZ, Gu Q, Wang C, Colton CK, Tang J, Kinoshita-Kawada M, Lee LY, Wood JD & Zhu MX (2004). 2-Aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3. J Biol Chem 279, 35741-35748.
-
(2004)
J Biol Chem
, vol.279
, pp. 35741-35748
-
-
Hu, H.Z.1
Gu, Q.2
Wang, C.3
Colton, C.K.4
Tang, J.5
Kinoshita-Kawada, M.6
Lee, L.Y.7
Wood, J.D.8
Zhu, M.X.9
-
28
-
-
0035669916
-
2-Aminoethoxydiphenyl borate (2-APB) inhibits capacitative calcium entry independently of the function of inositol 1,4,5-trisphosphate receptors
-
Iwasaki H, Mori Y, Hara Y, Uchida K, Zhou H & Mikoshiba K (2001). 2-Aminoethoxydiphenyl borate (2-APB) inhibits capacitative calcium entry independently of the function of inositol 1, 4, 5-trisphosphate receptors. Receptors Channels 7, 429-439.
-
(2001)
Receptors Channels
, vol.7
, pp. 429-439
-
-
Iwasaki, H.1
Mori, Y.2
Hara, Y.3
Uchida, K.4
Zhou, H.5
Mikoshiba, K.6
-
29
-
-
0025283839
-
Calcium oscillations in electrically non-excitable cells
-
Jacob R (1990). Calcium oscillations in electrically non-excitable cells. Biochim Biophys Acta 1052, 427-438.
-
(1990)
Biochim Biophys Acta
, vol.1052
, pp. 427-438
-
-
Jacob, R.1
-
30
-
-
51649121732
-
Functional stoichiometry of the unitary calcium-release-activated calcium channel
-
Ji W, Xu P, Li Z, Lu J, Liu L, Zhan Y, Chen Y, Hille B, Xu T & Chen L (2008). Functional stoichiometry of the unitary calcium-release-activated calcium channel. Proc Natl Acad Sci U S A 105, 13668-13673.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13668-13673
-
-
Ji, W.1
Xu, P.2
Li, Z.3
Lu, J.4
Liu, L.5
Zhan, Y.6
Chen, Y.7
Hille, B.8
Xu, T.9
Chen, L.10
-
31
-
-
35548936179
-
Pharmacological characterization and molecular determinants of the activation of transient receptor potential V2 channel orthologs by 2-aminoethoxydiphenyl borate
-
Juvin V, Penna A, Chemin J, Lin YL & Rassendren FA (2007). Pharmacological characterization and molecular determinants of the activation of transient receptor potential V2 channel orthologs by 2-aminoethoxydiphenyl borate. Mol Pharmacol 72, 1258-1268.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 1258-1268
-
-
Juvin, V.1
Penna, A.2
Chemin, J.3
Lin, Y.L.4
Rassendren, F.A.5
-
32
-
-
0036023404
-
Distinct properties of CRAC and MIC channels in RBL cells
-
Kozak JA, Kerschbaum HH & Cahalan MD (2002). Distinct properties of CRAC and MIC channels in RBL cells. J Gen Physiol 120, 221-235.
-
(2002)
J Gen Physiol
, vol.120
, pp. 221-235
-
-
Kozak, J.A.1
Kerschbaum, H.H.2
Cahalan, M.D.3
-
34
-
-
0035064074
-
Calcium signaling mechanisms in T lymphocytes
-
Lewis RS (2001). Calcium signaling mechanisms in T lymphocytes. Annu Rev Immunol 19, 497-521.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 497-521
-
-
Lewis, R.S.1
-
36
-
-
33646140352
-
Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7
-
Li M, Jiang J & Yue L (2006). Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7. J Gen Physiol 127, 525-537.
-
(2006)
J Gen Physiol
, vol.127
, pp. 525-537
-
-
Li, M.1
Jiang, J.2
Yue, L.3
-
37
-
-
51249097719
-
2+ current ICRAC
-
2+ current ICRAC. Arch Biochem Biophys 478, 110-118.
-
(2008)
Arch Biochem Biophys
, vol.478
, pp. 110-118
-
-
Li, Y.S.1
Wu, P.2
Zhou, X.Y.3
Chen, J.G.4
Cai, L.5
Wang, F.6
Xu, L.M.7
Zhang, X.L.8
Chen, Y.9
Liu, S.J.10
Huang, Y.P.11
Ye, D.Y.12
-
39
-
-
21844432686
-
2+ influx
-
2+ influx. Curr Biol 15, 1235-1241.
-
(2005)
Curr Biol
, vol.15
, pp. 1235-1241
-
-
Liou, J.1
Kim, M.L.2
Heo, W.D.3
Jones, J.T.4
Myers, J.W.5
Ferrell Jr, J.E.6
Meyer, T.7
-
40
-
-
34247386336
-
2+ channels with distinct functional properties
-
2+ channels with distinct functional properties. Curr Biol 17, 794-800.
-
(2007)
Curr Biol
, vol.17
, pp. 794-800
-
-
Lis, A.1
Peinelt, C.2
Beck, A.3
Parvez, S.4
Monteilh-Zoller, M.5
Fleig, A.6
Penner, R.7
-
41
-
-
78650070349
-
A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating
-
Lis A, Zierler S, Peinelt C, Fleig A & Penner R (2010). A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating. J Gen Physiol 136, 673-686.
-
(2010)
J Gen Physiol
, vol.136
, pp. 673-686
-
-
Lis, A.1
Zierler, S.2
Peinelt, C.3
Fleig, A.4
Penner, R.5
-
43
-
-
0034739254
-
STIM1: a novel phosphoprotein located at the cell surface
-
Manji SS, Parker NJ, Williams RT, Van Stekelenburg L, Pearson RB, Dziadek M & Smith PJ (2000). STIM1: a novel phosphoprotein located at the cell surface. Biochim Biophys Acta 1481, 147-155.
-
(2000)
Biochim Biophys Acta
, vol.1481
, pp. 147-155
-
-
Manji, S.S.1
Parker, N.J.2
Williams, R.T.3
Van Stekelenburg, L.4
Pearson, R.B.5
Dziadek, M.6
Smith, P.J.7
-
46
-
-
67649388419
-
Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain
-
Maruyama Y, Ogura T, Mio K, Kato K, Kaneko T, Kiyonaka S, Mori Y & Sato C (2009). Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain. J Biol Chem 284, 13676-13685.
-
(2009)
J Biol Chem
, vol.284
, pp. 13676-13685
-
-
Maruyama, Y.1
Ogura, T.2
Mio, K.3
Kato, K.4
Kaneko, T.5
Kiyonaka, S.6
Mori, Y.7
Sato, C.8
-
47
-
-
71449095831
-
2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia
-
2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia. J Allergy Clin Immunol 124, 1311-1318.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 1311-1318
-
-
McCarl, C.A.1
Picard, C.2
Khalil, S.3
Kawasaki, T.4
Rother, J.5
Papolos, A.6
Kutok, J.7
Hivroz, C.8
Ledeist, F.9
Plogmann, K.10
Ehl, S.11
Notheis, G.12
Albert, M.H.13
Belohradsky, B.H.14
Kirschner, J.15
Rao, A.16
Fischer, A.17
Feske, S.18
-
49
-
-
33747643506
-
Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1
-
Mercer JC, DeHaven WI, Smyth JT, Wedel B, Boyles RR, Bird GS & Putney JW Jr (2006). Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. J Biol Chem 281, 24979-24990.
-
(2006)
J Biol Chem
, vol.281
, pp. 24979-24990
-
-
Mercer, J.C.1
DeHaven, W.I.2
Smyth, J.T.3
Wedel, B.4
Boyles, R.R.5
Bird, G.S.6
Putney Jr, J.W.7
-
53
-
-
33947144703
-
2+-selective (ARC) channels without store depletion or translocation to the plasma membrane
-
2+-selective (ARC) channels without store depletion or translocation to the plasma membrane. J Physiol 579, 703-715.
-
(2007)
J Physiol
, vol.579
, pp. 703-715
-
-
Mignen, O.1
Thompson, J.L.2
Shuttleworth, T.J.3
-
55
-
-
38149040968
-
Orai1 subunit stoichiometry of the mammalian CRAC channel pore
-
Mignen O, Thompson JL & Shuttleworth TJ (2008b). Orai1 subunit stoichiometry of the mammalian CRAC channel pore. J Physiol 586, 419-425.
-
(2008)
J Physiol
, vol.586
, pp. 419-425
-
-
Mignen, O.1
Thompson, J.L.2
Shuttleworth, T.J.3
-
56
-
-
69949095093
-
2+-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits
-
2+-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits. J Physiol 587, 4181-4197.
-
(2009)
J Physiol
, vol.587
, pp. 4181-4197
-
-
Mignen, O.1
Thompson, J.L.2
Shuttleworth, T.J.3
-
59
-
-
77953532418
-
A novel native store-operated calcium channel encoded by Orai3: selective requirement of Orai3 versus Orai1 in estrogen receptor-positive versus estrogen receptor-negative breast cancer cells
-
Motiani RK, Abdullaev IF & Trebak M (2010). A novel native store-operated calcium channel encoded by Orai3: selective requirement of Orai3 versus Orai1 in estrogen receptor-positive versus estrogen receptor-negative breast cancer cells. J Biol Chem 285, 19173-19183.
-
(2010)
J Biol Chem
, vol.285
, pp. 19173-19183
-
-
Motiani, R.K.1
Abdullaev, I.F.2
Trebak, M.3
-
60
-
-
43149090543
-
Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation
-
Muik M, Frischauf I, Derler I, Fahrner M, Bergsmann J, Eder P, Schindl R, Hesch C, Polzinger B, Fritsch R, Kahr H, Madl J, Gruber H, Groschner K & Romanin C (2008). Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation. J Biol Chem 283, 8014-8022.
-
(2008)
J Biol Chem
, vol.283
, pp. 8014-8022
-
-
Muik, M.1
Frischauf, I.2
Derler, I.3
Fahrner, M.4
Bergsmann, J.5
Eder, P.6
Schindl, R.7
Hesch, C.8
Polzinger, B.9
Fritsch, R.10
Kahr, H.11
Madl, J.12
Gruber, H.13
Groschner, K.14
Romanin, C.15
-
62
-
-
0029739948
-
Identification of stromal cell products that interact with pre-B cells
-
Oritani K & Kincade PW (1996). Identification of stromal cell products that interact with pre-B cells. J Cell Biol 134, 771-782.
-
(1996)
J Cell Biol
, vol.134
, pp. 771-782
-
-
Oritani, K.1
Kincade, P.W.2
-
63
-
-
61349137530
-
STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1
-
Park CY, Hoover PJ, Mullins FM, Bachhawat P, Covington ED, Raunser S, Walz T, Garcia KC, Dolmetsch RE & Lewis RS (2009). STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1. Cell 136, 876-890.
-
(2009)
Cell
, vol.136
, pp. 876-890
-
-
Park, C.Y.1
Hoover, P.J.2
Mullins, F.M.3
Bachhawat, P.4
Covington, E.D.5
Raunser, S.6
Walz, T.7
Garcia, K.C.8
Dolmetsch, R.E.9
Lewis, R.S.10
-
64
-
-
0030588129
-
Molecular cloning of a novel human gene (D11S4896E) at chromosomal region 11p15.5
-
Parker NJ, Begley CG, Smith PJ & Fox RM (1996). Molecular cloning of a novel human gene (D11S4896E) at chromosomal region 11p15.5. Genomics 37, 253-256.
-
(1996)
Genomics
, vol.37
, pp. 253-256
-
-
Parker, N.J.1
Begley, C.G.2
Smith, P.J.3
Fox, R.M.4
-
65
-
-
47249095816
-
2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels
-
Peinelt C, Lis A, Beck A, Fleig A & Penner R (2008). 2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels. J Physiol 586, 3061-3073.
-
(2008)
J Physiol
, vol.586
, pp. 3061-3073
-
-
Peinelt, C.1
Lis, A.2
Beck, A.3
Fleig, A.4
Penner, R.5
-
66
-
-
33745759762
-
Amplification of CRAC current by STIM1 and CRACM1 (Orai1)
-
Peinelt C, Vig M, Koomoa DL, Beck A, Nadler MJ, Koblan-Huberson M, Lis A, Fleig A, Penner R & Kinet JP (2006). Amplification of CRAC current by STIM1 and CRACM1 (Orai1). Nat Cell Biol 8, 771-773.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 771-773
-
-
Peinelt, C.1
Vig, M.2
Koomoa, D.L.3
Beck, A.4
Nadler, M.J.5
Koblan-Huberson, M.6
Lis, A.7
Fleig, A.8
Penner, R.9
Kinet, J.P.10
-
67
-
-
55549083129
-
The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers
-
Penna A, Demuro A, Yeromin AV, Zhang SL, Safrina O, Parker I & Cahalan MD (2008). The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Nature 456, 116-120.
-
(2008)
Nature
, vol.456
, pp. 116-120
-
-
Penna, A.1
Demuro, A.2
Yeromin, A.V.3
Zhang, S.L.4
Safrina, O.5
Parker, I.6
Cahalan, M.D.7
-
68
-
-
0038420824
-
2-Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1,4,5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels
-
Peppiatt CM, Collins TJ, Mackenzie L, Conway SJ, Holmes AB, Bootman MD, Berridge MJ, Seo JT & Roderick HL (2003). 2-Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1, 4, 5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels. Cell Calcium 34, 97-108.
-
(2003)
Cell Calcium
, vol.34
, pp. 97-108
-
-
Peppiatt, C.M.1
Collins, T.J.2
Mackenzie, L.3
Conway, S.J.4
Holmes, A.B.5
Bootman, M.D.6
Berridge, M.J.7
Seo, J.T.8
Roderick, H.L.9
-
69
-
-
33748669602
-
Orai1 is an essential pore subunit of the CRAC channel
-
Prakriya M, Feske S, Gwack Y, Srikanth S, Rao A & Hogan PG (2006). Orai1 is an essential pore subunit of the CRAC channel. Nature 443, 230-233.
-
(2006)
Nature
, vol.443
, pp. 230-233
-
-
Prakriya, M.1
Feske, S.2
Gwack, Y.3
Srikanth, S.4
Rao, A.5
Hogan, P.G.6
-
71
-
-
0024397869
-
Characterization of cytosolic calcium oscillations induced by phenylephrine and vasopressin in single fura-2-loaded hepatocytes
-
Rooney TA, Sass EJ & Thomas AP (1989). Characterization of cytosolic calcium oscillations induced by phenylephrine and vasopressin in single fura-2-loaded hepatocytes. J Biol Chem 264, 17131-17141.
-
(1989)
J Biol Chem
, vol.264
, pp. 17131-17141
-
-
Rooney, T.A.1
Sass, E.J.2
Thomas, A.P.3
-
72
-
-
21044439334
-
2+ channel function
-
2+ channel function. J Cell Biol 169, 435-445.
-
(2005)
J Cell Biol
, vol.169
, pp. 435-445
-
-
Roos, J.1
DiGregorio, P.J.2
Yeromin, A.V.3
Ohlsen, K.4
Lioudyno, M.5
Zhang, S.6
Safrina, O.7
Kozak, J.A.8
Wagner, S.L.9
Cahalan, M.D.10
Velicelebi, G.11
Stauderman, K.A.12
-
73
-
-
0030882681
-
GOK: a gene at 11p15 involved in rhabdomyosarcoma and rhabdoid tumor development
-
Sabbioni S, Barbanti-Brodano G, Croce CM & Negrini M (1997). GOK: a gene at 11p15 involved in rhabdomyosarcoma and rhabdoid tumor development. Cancer Res 57, 4493-4497.
-
(1997)
Cancer Res
, vol.57
, pp. 4493-4497
-
-
Sabbioni, S.1
Barbanti-Brodano, G.2
Croce, C.M.3
Negrini, M.4
-
74
-
-
48049094820
-
2-Aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size
-
Schindl R, Bergsmann J, Frischauf I, Derler I, Fahrner M, Muik M, Fritsch R, Groschner K & Romanin C (2008). 2-Aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size. J Biol Chem 283, 20261-20267.
-
(2008)
J Biol Chem
, vol.283
, pp. 20261-20267
-
-
Schindl, R.1
Bergsmann, J.2
Frischauf, I.3
Derler, I.4
Fahrner, M.5
Muik, M.6
Fritsch, R.7
Groschner, K.8
Romanin, C.9
-
75
-
-
73349101911
-
2+ selectivity of Orai1/Orai3 heteromeric channel
-
2+ selectivity of Orai1/Orai3 heteromeric channel. Proc Natl Acad Sci U S A 106, 19623-19628.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 19623-19628
-
-
Schindl, R.1
Frischauf, I.2
Bergsmann, J.3
Muik, M.4
Derler, I.5
Lackner, B.6
Groschner, K.7
Romanin, C.8
-
76
-
-
67649653747
-
Properties of Orai1 mediated store-operated current depend on the expression levels of STIM1 and Orai1 proteins
-
Scrimgeour N, Litjens T, Ma L, Barritt GJ & Rychkov GY (2009). Properties of Orai1 mediated store-operated current depend on the expression levels of STIM1 and Orai1 proteins. J Physiol 587, 2903-2918.
-
(2009)
J Physiol
, vol.587
, pp. 2903-2918
-
-
Scrimgeour, N.1
Litjens, T.2
Ma, L.3
Barritt, G.J.4
Rychkov, G.Y.5
-
78
-
-
33746369780
-
Orai1 and STIM reconstitute store-operated calcium channel function
-
Soboloff J, Spassova MA, Tang XD, Hewavitharana T, Xu W & Gill DL (2006). Orai1 and STIM reconstitute store-operated calcium channel function. J Biol Chem 281, 20661-20665.
-
(2006)
J Biol Chem
, vol.281
, pp. 20661-20665
-
-
Soboloff, J.1
Spassova, M.A.2
Tang, X.D.3
Hewavitharana, T.4
Xu, W.5
Gill, D.L.6
-
80
-
-
33947128564
-
2+ entry
-
2+ entry. Biochem Biophys Res Commun 356, 45-52.
-
(2007)
Biochem Biophys Res Commun
, vol.356
, pp. 45-52
-
-
Takahashi, Y.1
Murakami, M.2
Watanabe, H.3
Hasegawa, H.4
Ohba, T.5
Munehisa, Y.6
Nobori, K.7
Ono, K.8
Iijima, T.9
Ito, H.10
-
81
-
-
0025753412
-
Spatial and temporal organization of calcium signalling in hepatocytes
-
Thomas AP, Renard DC & Rooney TA (1991). Spatial and temporal organization of calcium signalling in hepatocytes. Cell Calcium 12, 111-126.
-
(1991)
Cell Calcium
, vol.12
, pp. 111-126
-
-
Thomas, A.P.1
Renard, D.C.2
Rooney, T.A.3
-
82
-
-
77957733927
-
The N-terminal domain of Orai3 determines selectivity for activation of the store-independent ARC channel by arachidonic acid
-
Thompson JL, Mignen O & Shuttleworth TJ (2010). The N-terminal domain of Orai3 determines selectivity for activation of the store-independent ARC channel by arachidonic acid. Channels (Austin) 4, 398-410.
-
(2010)
Channels (Austin)
, vol.4
, pp. 398-410
-
-
Thompson, J.L.1
Mignen, O.2
Shuttleworth, T.J.3
-
83
-
-
80055005736
-
Orai channel-dependent activation of phospholipase C-δ: a novel mechanism for the effects of calcium entry on calcium oscillations
-
Thompson JL & Shuttleworth TJ (2011). Orai channel-dependent activation of phospholipase C-δ: a novel mechanism for the effects of calcium entry on calcium oscillations. J Physiol 589, 5057-5069.
-
(2011)
J Physiol
, vol.589
, pp. 5057-5069
-
-
Thompson, J.L.1
Shuttleworth, T.J.2
-
84
-
-
0037077249
-
Comparison of human TRPC3 channels in receptor-activated and store-operated modes - Differential sensitivity to channel blockers suggests fundamental differences in channel composition
-
Trebak M, Bird GSJ, McKay RR & Putney JW Jr (2002). Comparison of human TRPC3 channels in receptor-activated and store-operated modes - Differential sensitivity to channel blockers suggests fundamental differences in channel composition. J Biol Chem 277, 21617-21623.
-
(2002)
J Biol Chem
, vol.277
, pp. 21617-21623
-
-
Trebak, M.1
Bird, G.S.J.2
McKay, R.R.3
Putney Jr, J.W.4
-
85
-
-
33749987466
-
CRACM1 multimers form the ion-selective pore of the CRAC channel
-
Vig M, Beck A, Billingsley JM, Lis A, Parvez S, Peinelt C, Koomoa DL, Soboloff J, Gill DL, Fleig A, Kinet JP & Penner R (2006a). CRACM1 multimers form the ion-selective pore of the CRAC channel. Curr Biol 16, 2073-2079.
-
(2006)
Curr Biol
, vol.16
, pp. 2073-2079
-
-
Vig, M.1
Beck, A.2
Billingsley, J.M.3
Lis, A.4
Parvez, S.5
Peinelt, C.6
Koomoa, D.L.7
Soboloff, J.8
Gill, D.L.9
Fleig, A.10
Kinet, J.P.11
Penner, R.12
-
86
-
-
37349067978
-
Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels
-
Vig M, DeHaven WI, Bird GS, Billingsley JM, Wang H, Rao PE, Hutchings AB, Jouvin MH, Putney JW & Kinet JP (2008). Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels. Nat Immunol 9, 89-96.
-
(2008)
Nat Immunol
, vol.9
, pp. 89-96
-
-
Vig, M.1
DeHaven, W.I.2
Bird, G.S.3
Billingsley, J.M.4
Wang, H.5
Rao, P.E.6
Hutchings, A.B.7
Jouvin, M.H.8
Putney, J.W.9
Kinet, J.P.10
-
87
-
-
33744479684
-
2+ entry
-
2+ entry. Science 312, 1220-1223.
-
(2006)
Science
, vol.312
, pp. 1220-1223
-
-
Vig, M.1
Peinelt, C.2
Beck, A.3
Koomoa, D.L.4
Rabah, D.5
Koblan-Huberson, M.6
Kraft, S.7
Turner, H.8
Fleig, A.9
Penner, R.10
Kinet, J.P.11
-
88
-
-
0035930507
-
CaT1 and the calcium release-activated calcium channel manifest distinct pore properties
-
Voets T, Prenen J, Fleig A, Vennekens R, Watanabe H, Hoenderop JG, Bindels RJ, Droogmans G, Penner R & Nilius B (2001). CaT1 and the calcium release-activated calcium channel manifest distinct pore properties. J Biol Chem 276, 47767-47770.
-
(2001)
J Biol Chem
, vol.276
, pp. 47767-47770
-
-
Voets, T.1
Prenen, J.2
Fleig, A.3
Vennekens, R.4
Watanabe, H.5
Hoenderop, J.G.6
Bindels, R.J.7
Droogmans, G.8
Penner, R.9
Nilius, B.10
-
89
-
-
66149124488
-
STIM protein coupling in the activation of Orai channels
-
Wang Y, Deng X, Zhou Y, Hendron E, Mancarella S, Ritchie MF, Tang XD, Baba Y, Kurosaki T, Mori Y, Soboloff J & Gill DL (2009). STIM protein coupling in the activation of Orai channels. Proc Natl Acad Sci U S A 106, 7391-7396.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 7391-7396
-
-
Wang, Y.1
Deng, X.2
Zhou, Y.3
Hendron, E.4
Mancarella, S.5
Ritchie, M.F.6
Tang, X.D.7
Baba, Y.8
Kurosaki, T.9
Mori, Y.10
Soboloff, J.11
Gill, D.L.12
-
90
-
-
0035425189
-
Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins
-
Williams RT, Manji SS, Parker NJ, Hancock MS, Van Stekelenburg L, Eid JP, Senior PV, Kazenwadel JS, Shandala T, Saint R, Smith PJ & Dziadek MA (2001). Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins. Biochem J 357, 673-685.
-
(2001)
Biochem J
, vol.357
, pp. 673-685
-
-
Williams, R.T.1
Manji, S.S.2
Parker, N.J.3
Hancock, M.S.4
Van Stekelenburg, L.5
Eid, J.P.6
Senior, P.V.7
Kazenwadel, J.S.8
Shandala, T.9
Saint, R.10
Smith, P.J.11
Dziadek, M.A.12
-
91
-
-
0036537823
-
Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation
-
Williams RT, Senior PV, Van Stekelenburg L, Layton JE, Smith PJ & Dziadek MA (2002). Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation. Biochim Biophys Acta 1596, 131-137.
-
(2002)
Biochim Biophys Acta
, vol.1596
, pp. 131-137
-
-
Williams, R.T.1
Senior, P.V.2
Van Stekelenburg, L.3
Layton, J.E.4
Smith, P.J.5
Dziadek, M.A.6
-
94
-
-
33748655172
-
Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai
-
Yeromin AV, Zhang SL, Jiang W, Yu Y, Safrina O & Cahalan MD (2006). Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai. Nature 443, 226-229.
-
(2006)
Nature
, vol.443
, pp. 226-229
-
-
Yeromin, A.V.1
Zhang, S.L.2
Jiang, W.3
Yu, Y.4
Safrina, O.5
Cahalan, M.D.6
-
96
-
-
0033712477
-
Presenilin-mediated modulation of capacitative calcium entry
-
Yoo AS, Cheng I, Chung S, Grenfell TZ, Lee H, Pack-Chung E, Handler M, Shen J, Xia WM, Tesco G, Saunders AJ, Ding K, Frosch MP, Tanzi RE & Kim TW (2000). Presenilin-mediated modulation of capacitative calcium entry. Neuron 27, 561-572.
-
(2000)
Neuron
, vol.27
, pp. 561-572
-
-
Yoo, A.S.1
Cheng, I.2
Chung, S.3
Grenfell, T.Z.4
Lee, H.5
Pack-Chung, E.6
Handler, M.7
Shen, J.8
Xia, W.M.9
Tesco, G.10
Saunders, A.J.11
Ding, K.12
Frosch, M.P.13
Tanzi, R.E.14
Kim, T.W.15
-
97
-
-
47749147270
-
2+ channel activity of human Orai1 and Orai3
-
2+ channel activity of human Orai1 and Orai3. J Biol Chem 283, 17662-17671.
-
(2008)
J Biol Chem
, vol.283
, pp. 17662-17671
-
-
Zhang, S.L.1
Kozak, J.A.2
Jiang, W.3
Yeromin, A.V.4
Chen, J.5
Yu, Y.6
Penna, A.7
Shen, W.8
Chi, V.9
Cahalan, M.D.10
-
98
-
-
33745139810
-
2+ channel activity
-
2+ channel activity. Proc Natl Acad Sci U S A 103, 9357-9362.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 9357-9362
-
-
Zhang, S.L.1
Yeromin, A.V.2
Zhang, X.H.3
Yu, Y.4
Safrina, O.5
Penna, A.6
Roos, J.7
Stauderman, K.A.8
Cahalan, M.D.9
-
99
-
-
1842582607
-
2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2
-
2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2. J Biol Chem 279, 12427-12437.
-
(2004)
J Biol Chem
, vol.279
, pp. 12427-12437
-
-
Zitt, C.1
Strauss, B.2
Schwarz, E.C.3
Spaeth, N.4
Rast, G.5
Hatzelmann, A.6
Hoth, M.7
-
101
-
-
0030005990
-
Calcium-dependent potentiation of store-operated calcium channels in T lymphocytes
-
Zweifach A & Lewis RS (1996). Calcium-dependent potentiation of store-operated calcium channels in T lymphocytes. J Gen Physiol 107, 597-610.
-
(1996)
J Gen Physiol
, vol.107
, pp. 597-610
-
-
Zweifach, A.1
Lewis, R.S.2
|