메뉴 건너뛰기




Volumn 6, Issue 1, 2012, Pages 3-21

Antipsoriatic drug development: Challenges and new emerging therapies

Author keywords

Antipsoriatic therapies; Challenges; Drug discovery; Psoriasis; Psoriasis models; Satisfaction; Treatment

Indexed keywords

ADALIMUMAB; ALEFACEPT; ANTIPSORIASIS AGENT; BENZODIAZEPINE DERIVATIVE; CHINESE DRUG; CLOBETASOL; COLECALCIFEROL DERIVATIVE; CORTICOSTEROID; CYCLOPAMINE; CYCLOSPORIN A; DITHRANOL; EFALIZUMAB; ETANERCEPT; ETRETIN; HERBACEOUS AGENT; HYDROXYUREA; INFLIXIMAB; KERATOLYTIC AGENT; MESOINDIGO; METHOTREXATE; NATURAL PRODUCT; PLACEBO; PSORALEN; RETINOID; RETINOID DERIVATIVE; SALAZOSULFAPYRIDINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; UREA; USTEKINUMAB; VITAMIN D DERIVATIVE;

EID: 84855862661     PISSN: 1872213X     EISSN: None     Source Type: Journal    
DOI: 10.2174/187221312798889248     Document Type: Review
Times cited : (14)

References (169)
  • 1
    • 0035724176 scopus 로고    scopus 로고
    • Psoriasis--epidemiology and clinical spectrum
    • Christophers E. Psoriasis--epidemiology and clinical spectrum. Clin Exp Dermatol 2001; 26: 314-20.
    • (2001) Clin Exp Dermatol , vol.26 , pp. 314-320
    • Christophers, E.1
  • 2
    • 1842555395 scopus 로고    scopus 로고
    • Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction
    • Stern RS, Nijsten T, Feldman SR, Margolis DJ, Rolstad T. Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction. J Investig Dermatol Symp Proc 2004; 9: 136-9.
    • (2004) J Investig Dermatol Symp Proc , vol.9 , pp. 136-139
    • Stern, R.S.1    Nijsten, T.2    Feldman, S.R.3    Margolis, D.J.4    Rolstad, T.5
  • 4
    • 0035069606 scopus 로고    scopus 로고
    • The impact of psoriasis on quality of life: Results of a 1998 National Psoriasis Foundation patient-membership survey
    • Krueger G, Koo J, Lebwohl M, Menter A, Stern RS, Rolstad T. The impact of psoriasis on quality of life: Results of a 1998 National Psoriasis Foundation patient-membership survey. Arch Dermatol 2001; 137: 280-4.
    • (2001) Arch Dermatol , vol.137 , pp. 280-284
    • Krueger, G.1    Koo, J.2    Lebwohl, M.3    Menter, A.4    Stern, R.S.5    Rolstad, T.6
  • 5
    • 33748448266 scopus 로고    scopus 로고
    • European patient perspectives on the impact of psoriasis: The EUROPSO patient membership survey
    • Dubertret L, Mrowietz U, Ranki A, van de Kerkhof PC, Chimenti S, Lotti T, et al. European patient perspectives on the impact of psoriasis: The EUROPSO patient membership survey. Br J Dermatol 2006; 155: 729-36.
    • (2006) Br J Dermatol , vol.155 , pp. 729-736
    • Dubertret, L.1    Mrowietz, U.2    Ranki, A.3    van de Kerkhof, P.C.4    Chimenti, S.5    Lotti, T.6
  • 6
    • 39749161683 scopus 로고    scopus 로고
    • Drug delivery and formulations for the topical treatment of psoriasis
    • Su YH, Fang JY. Drug delivery and formulations for the topical treatment of psoriasis. Expert Opin Drug Deliv 2008; 5: 235-49.
    • (2008) Expert Opin Drug Deliv , vol.5 , pp. 235-249
    • Su, Y.H.1    Fang, J.Y.2
  • 7
    • 33646589648 scopus 로고    scopus 로고
    • The long-term efficacy and safety of new biological therapies for psoriasis
    • Papp KA. The long-term efficacy and safety of new biological therapies for psoriasis. Arch Dermatol Res 2006; 298: 7-15.
    • (2006) Arch Dermatol Res , vol.298 , pp. 7-15
    • Papp, K.A.1
  • 8
    • 17644376546 scopus 로고    scopus 로고
    • Traditional therapies in the management of moderate to severe chronic plaque psoriasis: An assessment of the benefits and risks
    • Naldi L, Griffiths CE. Traditional therapies in the management of moderate to severe chronic plaque psoriasis: An assessment of the benefits and risks. Br J Dermatol 2005; 152: 597-615.
    • (2005) Br J Dermatol , vol.152 , pp. 597-615
    • Naldi, L.1    Griffiths, C.E.2
  • 10
    • 0042905776 scopus 로고    scopus 로고
    • The increased risk of skin cancer is persistent after discontinuation of psoralen+ultraviolet A: A cohort study
    • Nijsten TE, Stern RS. The increased risk of skin cancer is persistent after discontinuation of psoralen+ultraviolet A: A cohort study. J Invest Dermatol 2003; 121: 252-8.
    • (2003) J Invest Dermatol , vol.121 , pp. 252-258
    • Nijsten, T.E.1    Stern, R.S.2
  • 13
    • 4544388284 scopus 로고    scopus 로고
    • Biological therapies in the systemic management of psoriasis: International Consensus Conference
    • Sterry W, Barker J, Boehncke WH, Bos JD, Chimenti S, Christophers E, et al. Biological therapies in the systemic management of psoriasis: International Consensus Conference. Br J Dermatol 2004; 151 (Suppl 69): 3-17.
    • (2004) Br J Dermatol , vol.151 , Issue.SUPPL. 69 , pp. 3-17
    • Sterry, W.1    Barker, J.2    Boehncke, W.H.3    Bos, J.D.4    Chimenti, S.5    Christophers, E.6
  • 14
    • 0036239694 scopus 로고    scopus 로고
    • Novel immune-based therapies for psoriasis
    • Kirby B, Griffiths CE. Novel immune-based therapies for psoriasis. Br J Dermatol 2002; 146: 546-51.
    • (2002) Br J Dermatol , vol.146 , pp. 546-551
    • Kirby, B.1    Griffiths, C.E.2
  • 15
    • 0037930034 scopus 로고    scopus 로고
    • Clinical response to alefacept: Results of a phase 3 study of intramuscular administration of alefacept in patients with chronic plaque psoriasis
    • Ortonne JP. Clinical response to alefacept: Results of a phase 3 study of intramuscular administration of alefacept in patients with chronic plaque psoriasis. J Eur Acad Dermatol Venereol 2003; 17 (Suppl 2): 12-6.
    • (2003) J Eur Acad Dermatol Venereol , vol.17 , Issue.SUPPL. 2 , pp. 12-16
    • Ortonne, J.P.1
  • 16
    • 0346515709 scopus 로고    scopus 로고
    • Efalizumab for patients with moderate to severe plaque psoriasis: A randomized controlled trial
    • Gordon KB, Papp KA, Hamilton TK, Walicke PA, Dummer W, Li N, et al. Efalizumab for patients with moderate to severe plaque psoriasis: A randomized controlled trial. JAMA 2003; 290: 3073-80.
    • (2003) JAMA , vol.290 , pp. 307-338
    • Gordon, K.B.1    Papp, K.A.2    Hamilton, T.K.3    Walicke, P.A.4    Dummer, W.5    Li, N.6
  • 19
    • 0037373957 scopus 로고    scopus 로고
    • Anti-tumour necrosis factor agents and tuberculosis risk: Mechanisms of action and clinical management
    • Gardam MA, Keystone EC, Menzies R, Manners S, Skamene E, Long R, et al. Anti-tumour necrosis factor agents and tuberculosis risk: Mechanisms of action and clinical management. Lancet Infect Dis 2003; 3: 148-55.
    • (2003) Lancet Infect Dis , vol.3 , pp. 148-155
    • Gardam, M.A.1    Keystone, E.C.2    Menzies, R.3    Manners, S.4    Skamene, E.5    Long, R.6
  • 21
    • 0037672879 scopus 로고    scopus 로고
    • Case reports of heart failure after therapy with a tumor necrosis factor antagonist
    • Kwon HJ, Cote TR, Cuffe MS, Kramer JM, Braun MM. Case reports of heart failure after therapy with a tumor necrosis factor antagonist. Ann Intern Med 2003; 138: 807-11.
    • (2003) Ann Intern Med , vol.138 , pp. 807-811
    • Kwon, H.J.1    Cote, T.R.2    Cuffe, M.S.3    Kramer, J.M.4    Braun, M.M.5
  • 22
    • 0035674613 scopus 로고    scopus 로고
    • Demyelination occurring during anti-tumor necrosis factor alpha therapy for inflammatory arthritides
    • Mohan N, Edwards ET, Cupps TR, Oliverio PJ, Sandberg G, Crayton H, et al. Demyelination occurring during anti-tumor necrosis factor alpha therapy for inflammatory arthritides. Arthritis Rheum 2001; 44: 2862-9.
    • (2001) Arthritis Rheum , vol.44 , pp. 2862-2869
    • Mohan, N.1    Edwards, E.T.2    Cupps, T.R.3    Oliverio, P.J.4    Sandberg, G.5    Crayton, H.6
  • 23
    • 0037434552 scopus 로고    scopus 로고
    • Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease
    • Baert F, Noman M, Vermeire S, Van Assche G, G DH, Carbonez A, et al. Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease. N Engl J Med 2003; 348: 601-8.
    • (2003) N Engl J Med , vol.348 , pp. 601-608
    • Baert, F.1    Noman, M.2    Vermeire, S.3    van Assche, G.G.D.H.4    Carbonez, A.5
  • 25
    • 0024415118 scopus 로고
    • Erythrodermic psoriasis. Precipitating factors, course, and prognosis in 50 patients
    • Boyd AS, Menter A. Erythrodermic psoriasis. Precipitating factors, course, and prognosis in 50 patients. J Am Acad Dermatol 1989; 21: 985-91.
    • (1989) J Am Acad Dermatol , vol.21 , pp. 985-991
    • Boyd, A.S.1    Menter, A.2
  • 27
    • 0036050934 scopus 로고    scopus 로고
    • Generalised pustular psoriasis induced by cyclosporin a withdrawal responding to the tumour necrosis factor alpha inhibitor etanercept
    • Kamarashev J, Lor P, Forster A, Heinzerling L, Burg G, Nestle FO. Generalised pustular psoriasis induced by cyclosporin a withdrawal responding to the tumour necrosis factor alpha inhibitor etanercept. Dermatology 2002; 205: 213-6.
    • (2002) Dermatology , vol.205 , pp. 213-216
    • Kamarashev, J.1    Lor, P.2    Forster, A.3    Heinzerling, L.4    Burg, G.5    Nestle, F.O.6
  • 28
    • 59649105640 scopus 로고    scopus 로고
    • Interplay between keratinocytes and immune cells--recent insights into psoriasis pathogenesis
    • Tonel G, Conrad C. Interplay between keratinocytes and immune cells--recent insights into psoriasis pathogenesis. Int J Biochem Cell Biol 2009; 41: 963-8.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 963-968
    • Tonel, G.1    Conrad, C.2
  • 29
    • 0028929039 scopus 로고
    • Differences in involucrin immunolabeling within cornified cell envelopes in normal and psoriatic epidermis
    • Ishida-Yamamoto A, Iizuka H. Differences in involucrin immunolabeling within cornified cell envelopes in normal and psoriatic epidermis. J Invest Dermatol 1995; 104: 391-5.
    • (1995) J Invest Dermatol , vol.104 , pp. 391-395
    • Ishida-Yamamoto, A.1    Iizuka, H.2
  • 30
    • 0028927968 scopus 로고
    • Altered keratinocyte growth and differentiation in psoriasis
    • McKay IA, Leigh IM. Altered keratinocyte growth and differentiation in psoriasis. Clin Dermatol 1995; 13: 105-14.
    • (1995) Clin Dermatol , vol.13 , pp. 105-114
    • McKay, I.A.1    Leigh, I.M.2
  • 31
    • 2342461732 scopus 로고    scopus 로고
    • Unique keratinization process in psoriasis: Late differentiation markers are abolished because of the premature cell death
    • Iizuka H, Takahashi H, Honma M, Ishida-Yamamoto A. Unique keratinization process in psoriasis: Late differentiation markers are abolished because of the premature cell death. J Dermatol 2004; 31: 271-6.
    • (2004) J Dermatol , vol.31 , pp. 271-276
    • Iizuka, H.1    Takahashi, H.2    Honma, M.3    Ishida-Yamamoto, A.4
  • 32
    • 25444435193 scopus 로고    scopus 로고
    • Getting under the skin: The immunogenetics of psoriasis
    • Bowcock AM, Krueger JG. Getting under the skin: The immunogenetics of psoriasis. Nat Rev Immunol 2005; 5: 699-711.
    • (2005) Nat Rev Immunol , vol.5 , pp. 699-711
    • Bowcock, A.M.1    Krueger, J.G.2
  • 33
    • 22344438901 scopus 로고    scopus 로고
    • Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production
    • Nestle FO, Conrad C, Tun-Kyi A, Homey B, Gombert M, Boyman O, et al. Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production. J Exp Med 2005; 202: 135-43.
    • (2005) J Exp Med , vol.202 , pp. 135-143
    • Nestle, F.O.1    Conrad, C.2    Tun-Kyi, A.3    Homey, B.4    Gombert, M.5    Boyman, O.6
  • 34
    • 33847279025 scopus 로고    scopus 로고
    • Pathogenesis and therapy of psoriasis
    • Lowes MA, Bowcock AM, Krueger JG. Pathogenesis and therapy of psoriasis. Nature 2007; 445: 866-73.
    • (2007) Nature , vol.445 , pp. 866-873
    • Lowes, M.A.1    Bowcock, A.M.2    Krueger, J.G.3
  • 36
    • 33846906224 scopus 로고    scopus 로고
    • Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
    • Zheng Y, Danilenko DM, Valdez P, Kasman I, Eastham-Anderson J, Wu J, et al. Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 2007; 445: 648-51.
    • (2007) Nature , vol.445 , pp. 648-651
    • Zheng, Y.1    Danilenko, D.M.2    Valdez, P.3    Kasman, I.4    Eastham-Anderson, J.5    Wu, J.6
  • 37
    • 0030687496 scopus 로고    scopus 로고
    • Altered expression of keratinocyte growth factor and its receptor in psoriasis
    • Finch PW, Murphy F, Cardinale I, Krueger JG. Altered expression of keratinocyte growth factor and its receptor in psoriasis. Am J Pathol 1997; 151: 1619-28.
    • (1997) Am J Pathol , vol.151 , pp. 1619-1628
    • Finch, P.W.1    Murphy, F.2    Cardinale, I.3    Krueger, J.G.4
  • 38
    • 34250684883 scopus 로고    scopus 로고
    • The evolution of the psoriatic lesion
    • van de Kerkhof PC. The evolution of the psoriatic lesion. Br J Dermatol 2007; 157: 4-15.
    • (2007) Br J Dermatol , vol.157 , pp. 4-15
    • van de Kerkhof, P.C.1
  • 39
    • 0036151252 scopus 로고    scopus 로고
    • Human leukocyte elastase induces keratinocyte proliferation in vitro and in vivo
    • Rogalski C, Meyer-Hoffert U, Proksch E, Wiedow O. Human leukocyte elastase induces keratinocyte proliferation in vitro and in vivo. J Invest Dermatol 2002; 118: 49-54.
    • (2002) J Invest Dermatol , vol.118 , pp. 49-54
    • Rogalski, C.1    Meyer-Hoffert, U.2    Proksch, E.3    Wiedow, O.4
  • 40
    • 0036344554 scopus 로고    scopus 로고
    • Clinical features of psoriatic arthritis
    • Krueger GG. Clinical features of psoriatic arthritis. Am J Manag Care 2002; 8: S160-70.
    • (2002) Am J Manag Care , vol.8
    • Krueger, G.G.1
  • 43
    • 68149124213 scopus 로고    scopus 로고
    • Depression and quality of life in psoriasis
    • Van Voorhees AS, Fried R. Depression and quality of life in psoriasis. Postgrad Med 2009; 121: 154-61.
    • (2009) Postgrad Med , vol.121 , pp. 154-161
    • van Voorhees, A.S.1    Fried, R.2
  • 44
    • 0030905742 scopus 로고    scopus 로고
    • Psoriasis and sex: A study of moderately to severely affected patients
    • Gupta MA, Gupta AK. Psoriasis and sex: A study of moderately to severely affected patients. Int J Dermatol 1997; 36: 259-62.
    • (1997) Int J Dermatol , vol.36 , pp. 259-262
    • Gupta, M.A.1    Gupta, A.K.2
  • 45
    • 0035040125 scopus 로고    scopus 로고
    • The impact of psoriasis on quality of life
    • de Arruda LH, De Moraes AP. The impact of psoriasis on quality of life. Br J Dermatol 2001; 144 (Suppl 58): 33-6.
    • (2001) Br J Dermatol , vol.144 , Issue.SUPPL. 58 , pp. 33-36
    • de Arruda, L.H.1    de Moraes, A.P.2
  • 48
    • 4944231501 scopus 로고    scopus 로고
    • Prevalence of symptoms experienced by patients with different clinical types of psoriasis
    • Sampogna F, Gisondi P, Melchi CF, Amerio P, Girolomoni G, Abeni D. Prevalence of symptoms experienced by patients with different clinical types of psoriasis. Br J Dermatol 2004; 151: 594-9.
    • (2004) Br J Dermatol , vol.151 , pp. 594-599
    • Sampogna, F.1    Gisondi, P.2    Melchi, C.F.3    Amerio, P.4    Girolomoni, G.5    Abeni, D.6
  • 49
    • 70349312687 scopus 로고    scopus 로고
    • Economic burden of psoriasis compared to the general population and stratified by disease severity
    • Yu AP, Tang J, Xie J, Wu EQ, Gupta SR, Bao Y, et al. Economic burden of psoriasis compared to the general population and stratified by disease severity. Curr Med Res Opin 2009; 25: 2429-38.
    • (2009) Curr Med Res Opin , vol.25 , pp. 2429-2438
    • Yu, A.P.1    Tang, J.2    Xie, J.3    Wu, E.Q.4    Gupta, S.R.5    Bao, Y.6
  • 50
    • 37249004404 scopus 로고    scopus 로고
    • The risk of mortality in patients with psoriasis: Results from a population-based study
    • Gelfand JM, Troxel AB, Lewis JD, Kurd SK, Shin DB, Wang X, et al. The risk of mortality in patients with psoriasis: Results from a population-based study. Arch Dermatol 2007; 143: 1493-9.
    • (2007) Arch Dermatol , vol.143 , pp. 1493-1499
    • Gelfand, J.M.1    Troxel, A.B.2    Lewis, J.D.3    Kurd, S.K.4    Shin, D.B.5    Wang, X.6
  • 51
    • 49249102223 scopus 로고    scopus 로고
    • Long-term prognosis in patients with psoriasis
    • Gulliver W. Long-term prognosis in patients with psoriasis. Br J Dermatol 2008; 159 (Suppl 2): 2-9.
    • (2008) Br J Dermatol , vol.159 , Issue.SUPPL. 2 , pp. 2-9
    • Gulliver, W.1
  • 52
    • 0028918535 scopus 로고
    • The effect of severe psoriasis on the quality of life of 369 patients
    • Finlay AY, Coles EC. The effect of severe psoriasis on the quality of life of 369 patients. Br J Dermatol 1995; 132: 236-44.
    • (1995) Br J Dermatol , vol.132 , pp. 236-244
    • Finlay, A.Y.1    Coles, E.C.2
  • 56
    • 34250189508 scopus 로고    scopus 로고
    • How to position antipsoriatic treatments?
    • van de Kerkhof PC. How to position antipsoriatic treatments? J Dermatolog Treat 2006; 17: 325-6.
    • (2006) J Dermatolog Treat , vol.17 , pp. 325-326
    • van de Kerkhof, P.C.1
  • 57
    • 0035034956 scopus 로고    scopus 로고
    • Combination therapy with vitamin D analogues
    • Lamba S, Lebwohl M. Combination therapy with vitamin D analogues. Br J Dermatol 2001; 144 (Suppl 58): 27-32.
    • (2001) Br J Dermatol , vol.144 , Issue.SUPPL. 58 , pp. 27-32
    • Lamba, S.1    Lebwohl, M.2
  • 58
    • 0030811606 scopus 로고    scopus 로고
    • Tazarotene gel, a new retinoid, for topical therapy of psoriasis: Vehicle-controlled study of safety, efficacy, and duration of therapeutic effect
    • Weinstein GD, Krueger GG, Lowe NJ, Duvic M, Friedman DJ, Jegasothy BV, et al. Tazarotene gel, a new retinoid, for topical therapy of psoriasis: Vehicle-controlled study of safety, efficacy, and duration of therapeutic effect. J Am Acad Dermatol 1997; 37: 85-92.
    • (1997) J Am Acad Dermatol , vol.37 , pp. 85-92
    • Weinstein, G.D.1    Krueger, G.G.2    Lowe, N.J.3    Duvic, M.4    Friedman, D.J.5    Jegasothy, B.V.6
  • 59
    • 0037947382 scopus 로고    scopus 로고
    • Tazarotene cream in the treatment of psoriasis: Two multicenter, double-blind, randomized, vehicle-controlled studies of the safety and efficacy of tazarotene creams 0.05% and 0.1% applied once daily for 12 weeks
    • Weinstein GD, Koo JY, Krueger GG, Lebwohl MG, Lowe NJ, Menter MA, et al. Tazarotene cream in the treatment of psoriasis: Two multicenter, double-blind, randomized, vehicle-controlled studies of the safety and efficacy of tazarotene creams 0.05% and 0.1% applied once daily for 12 weeks. J Am Acad Dermatol 2003; 48: 760-7.
    • (2003) J Am Acad Dermatol , vol.48 , pp. 760-767
    • Weinstein, G.D.1    Koo, J.Y.2    Krueger, G.G.3    Lebwohl, M.G.4    Lowe, N.J.5    Menter, M.A.6
  • 60
    • 0035725629 scopus 로고    scopus 로고
    • Phototherapy for psoriasis
    • Honigsmann H. Phototherapy for psoriasis. Clin Exp Dermatol 2001; 26: 343-50.
    • (2001) Clin Exp Dermatol , vol.26 , pp. 343-350
    • Honigsmann, H.1
  • 62
    • 0023758687 scopus 로고
    • Non-melanoma skin cancer occurring in patients treated with PUVA five to ten years after first treatment
    • Stern RS, Lange R. Non-melanoma skin cancer occurring in patients treated with PUVA five to ten years after first treatment. J Invest Dermatol 1988; 91: 120-4.
    • (1988) J Invest Dermatol , vol.91 , pp. 120-124
    • Stern, R.S.1    Lange, R.2
  • 63
    • 0034753878 scopus 로고    scopus 로고
    • Treatment of psoriasis. Part 2. Systemic therapies
    • Lebwohl M, Ali S. Treatment of psoriasis. Part 2. Systemic therapies. J Am Acad Dermatol 2001; 45: 649-61.
    • (2001) J Am Acad Dermatol , vol.45 , pp. 649-661
    • Lebwohl, M.1    Ali, S.2
  • 64
    • 70349487341 scopus 로고    scopus 로고
    • Reduced libido and erectile dysfunction: Rarely reported side-effects of methotrexate
    • Wylie G, Evans CD, Gupta G. Reduced libido and erectile dysfunction: Rarely reported side-effects of methotrexate. Clin Exp Dermatol 2009; 34: e234.
    • (2009) Clin Exp Dermatol , vol.34
    • Wylie, G.1    Evans, C.D.2    Gupta, G.3
  • 66
    • 16144364925 scopus 로고    scopus 로고
    • Long-term low-dose cyclosporine therapy for severe psoriasis: Effects on renal function and structure
    • Lowe NJ, Wieder JM, Rosenbach A, Johnson K, Kunkel R, Bainbridge C, et al. Long-term low-dose cyclosporine therapy for severe psoriasis: Effects on renal function and structure. J Am Acad Dermatol 1996; 35: 710-9.
    • (1996) J Am Acad Dermatol , vol.35 , pp. 710-719
    • Lowe, N.J.1    Wieder, J.M.2    Rosenbach, A.3    Johnson, K.4    Kunkel, R.5    Bainbridge, C.6
  • 67
    • 0032858530 scopus 로고    scopus 로고
    • Treatment of severe psoriasis with fumaric acid esters: Scientific background and guidelines for therapeutic use. The German Fumaric Acid Ester Consensus Conference
    • Mrowietz U, Christophers E, Altmeyer P. Treatment of severe psoriasis with fumaric acid esters: Scientific background and guidelines for therapeutic use. The German Fumaric Acid Ester Consensus Conference. Br J Dermatol 1999; 141: 424-9.
    • (1999) Br J Dermatol , vol.141 , pp. 424-429
    • Mrowietz, U.1    Christophers, E.2    Altmeyer, P.3
  • 69
    • 65649117851 scopus 로고    scopus 로고
    • Efalizumab treatment of psoriasis vulgaris: A cohort study in outpatient clinical practice
    • Puig L, Roe E, Garcia-Navarro X, Corella F, Alomar A. Efalizumab treatment of psoriasis vulgaris: A cohort study in outpatient clinical practice. Clin Exp Dermatol 2009; 34: 469-75.
    • (2009) Clin Exp Dermatol , vol.34 , pp. 469-475
    • Puig, L.1    Roe, E.2    Garcia-Navarro, X.3    Corella, F.4    Alomar, A.5
  • 70
    • 67650663801 scopus 로고    scopus 로고
    • Efalizumab discontinuation: A practical strategy
    • Pugashetti R, Koo J. Efalizumab discontinuation: A practical strategy. J Dermatolog Treat 2009; 20: 132-6.
    • (2009) J Dermatolog Treat , vol.20 , pp. 132-136
    • Pugashetti, R.1    Koo, J.2
  • 71
    • 34249039292 scopus 로고    scopus 로고
    • A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis
    • Gottlieb AB, Cooper KD, McCormick TS, Toichi E, Everitt DE, Frederick B, et al. A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis. Curr Med Res Opin 2007; 23: 1081-92.
    • (2007) Curr Med Res Opin , vol.23 , pp. 1081-1092
    • Gottlieb, A.B.1    Cooper, K.D.2    McCormick, T.S.3    Toichi, E.4    Everitt, D.E.5    Frederick, B.6
  • 73
    • 54449085378 scopus 로고    scopus 로고
    • Long-term treatment with infliximab in inflammatory bowel disease: Safety and tolerability issues
    • Caviglia R, Boskoski I, Cicala M. Long-term treatment with infliximab in inflammatory bowel disease: Safety and tolerability issues. Expert Opin Drug Saf 2008; 7: 617-32.
    • (2008) Expert Opin Drug Saf , vol.7 , pp. 617-632
    • Caviglia, R.1    Boskoski, I.2    Cicala, M.3
  • 74
    • 67449102437 scopus 로고    scopus 로고
    • Postmarketing surveillance of the safety and effectiveness of etanercept in Japan
    • Koike T, Harigai M, Inokuma S, Inoue K, Ishiguro N, Ryu J, et al. Postmarketing surveillance of the safety and effectiveness of etanercept in Japan. J Rheumatol 2009; 36: 898-906.
    • (2009) J Rheumatol , vol.36 , pp. 898-906
    • Koike, T.1    Harigai, M.2    Inokuma, S.3    Inoue, K.4    Ishiguro, N.5    Ryu, J.6
  • 75
    • 70149113953 scopus 로고    scopus 로고
    • Safety and efficacy of once weekly etanercept 0.8 mg/kg in a multicentre 12 week trial in active polyarticular course juvenile idiopathic arthritis
    • Horneff G, Ebert A, Fitter S, Minden K, Foeldvari I, Kummerle-Deschner J, et al. Safety and efficacy of once weekly etanercept 0.8 mg/kg in a multicentre 12 week trial in active polyarticular course juvenile idiopathic arthritis. Rheumatology (Oxford) 2009; 48: 916-9.
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 916-919
    • Horneff, G.1    Ebert, A.2    Fitter, S.3    Minden, K.4    Foeldvari, I.5    Kummerle-Deschner, J.6
  • 76
    • 33847389242 scopus 로고    scopus 로고
    • Complications and adverse reactions in the use of newer biologic agents
    • Callen JP. Complications and adverse reactions in the use of newer biologic agents. Semin Cutan Med Surg 2007; 26: 6-14.
    • (2007) Semin Cutan Med Surg , vol.26 , pp. 6-14
    • Callen, J.P.1
  • 77
    • 33646696885 scopus 로고    scopus 로고
    • Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
    • Bongartz T, Sutton AJ, Sweeting MJ, Buchan I, Matteson EL, Montori V. Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA 2006; 295: 2275-85.
    • (2006) JAMA , vol.295 , pp. 2275-2285
    • Bongartz, T.1    Sutton, A.J.2    Sweeting, M.J.3    Buchan, I.4    Matteson, E.L.5    Montori, V.6
  • 78
    • 48449090541 scopus 로고    scopus 로고
    • Emollients, moisturizers, and keratolytic agents in psoriasis
    • Fluhr JW, Cavallotti C, Berardesca E. Emollients, moisturizers, and keratolytic agents in psoriasis. Clin Dermatol 2008; 26: 380-6.
    • (2008) Clin Dermatol , vol.26 , pp. 380-386
    • Fluhr, J.W.1    Cavallotti, C.2    Berardesca, E.3
  • 80
    • 28444454046 scopus 로고    scopus 로고
    • How patients experience psoriasis: Results from a European survey
    • Fouere S, Adjadj L, Pawin H. How patients experience psoriasis: Results from a European survey. J Eur Acad Dermatol Venereol 2005; 19 (Suppl 3): 2-6.
    • (2005) J Eur Acad Dermatol Venereol , vol.19 , Issue.SUPPL. 3 , pp. 2-6
    • Fouere, S.1    Adjadj, L.2    Pawin, H.3
  • 81
    • 0034805313 scopus 로고    scopus 로고
    • Treatment of psoriasis. Part 1. Topical therapy and phototherapy
    • Lebwohl M, Ali S. Treatment of psoriasis. Part 1. Topical therapy and phototherapy. J Am Acad Dermatol 2001; 45: 487-98.
    • (2001) J Am Acad Dermatol , vol.45 , pp. 487-498
    • Lebwohl, M.1    Ali, S.2
  • 82
    • 58349083267 scopus 로고    scopus 로고
    • Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms
    • Warren RB, Smith RL, Campalani E, Eyre S, Smith CH, Barker JN, et al. Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms. Br J Dermatol 2009; 160: 438-41.
    • (2009) Br J Dermatol , vol.160 , pp. 438-441
    • Warren, R.B.1    Smith, R.L.2    Campalani, E.3    Eyre, S.4    Smith, C.H.5    Barker, J.N.6
  • 84
    • 39549104281 scopus 로고    scopus 로고
    • Quality of life and treatment satisfaction among patients with psoriasis and psoriatic arthritis and patients with psoriasis only: Results of the 2005 Spring US National Psoriasis Foundation Survey
    • Ciocon DH, Horn EJ, Kimball AB. Quality of life and treatment satisfaction among patients with psoriasis and psoriatic arthritis and patients with psoriasis only: Results of the 2005 Spring US National Psoriasis Foundation Survey. Am J Clin Dermatol 2008; 9: 111-7.
    • (2008) Am J Clin Dermatol , vol.9 , pp. 111-117
    • Ciocon, D.H.1    Horn, E.J.2    Kimball, A.B.3
  • 85
    • 39049169482 scopus 로고    scopus 로고
    • Adherence to treatment in patients with psoriasis vulgaris: Turkish experience
    • Gokdemir G, Ari S, Koslu A. Adherence to treatment in patients with psoriasis vulgaris: Turkish experience. J Eur Acad Dermatol Venereol 2008; 22: 330-5.
    • (2008) J Eur Acad Dermatol Venereol , vol.22 , pp. 330-335
    • Gokdemir, G.1    Ari, S.2    Koslu, A.3
  • 86
    • 77955867600 scopus 로고    scopus 로고
    • Treatment patterns and perceptions of treatment attributes satisfaction and effectiveness among patients with psoriasis
    • Di Bonaventura M, Wagner S, Waters H, Carter C. Treatment patterns and perceptions of treatment attributes satisfaction and effectiveness among patients with psoriasis. J Drugs Dermatol 2010; 9: 938-44.
    • (2010) J Drugs Dermatol , vol.9 , pp. 938-944
    • Di Bonaventura, M.1    Wagner, S.2    Waters, H.3    Carter, C.4
  • 87
    • 78649405178 scopus 로고    scopus 로고
    • A Canadian online survey to evaluate awareness and treatment satisfaction in individuals with moderate to severe plaque psoriasis
    • Poulin Y, Papp KA, Wasel NR, Andrew R, Fraquelli E, Bernstein G, et al. A Canadian online survey to evaluate awareness and treatment satisfaction in individuals with moderate to severe plaque psoriasis. Int J Dermatol 2010; 49: 1368-75.
    • (2010) Int J Dermatol , vol.49 , pp. 1368-1375
    • Poulin, Y.1    Papp, K.A.2    Wasel, N.R.3    Andrew, R.4    Fraquelli, E.5    Bernstein, G.6
  • 89
    • 0142165866 scopus 로고    scopus 로고
    • Complementary medicine and psoriasis: Linking the patient's outlook with evidence-based medicine
    • Ben-Arye E, Ziv M, Frenkel M, Lavi I, Rosenman D. Complementary medicine and psoriasis: Linking the patient's outlook with evidence-based medicine. Dermatology 2003; 207: 302-7.
    • (2003) Dermatology , vol.207 , pp. 302-307
    • Ben-Arye, E.1    Ziv, M.2    Frenkel, M.3    Lavi, I.4    Rosenman, D.5
  • 112
    • 3242729202 scopus 로고    scopus 로고
    • Human leukocyte elastase induces keratinocyte proliferation by epidermal growth factor receptor activation
    • Meyer-Hoffert U, Wingertszahn J, Wiedow O. Human leukocyte elastase induces keratinocyte proliferation by epidermal growth factor receptor activation. J Invest Dermatol 2004; 123: 338-45.
    • (2004) J Invest Dermatol , vol.123 , pp. 338-345
    • Meyer-Hoffert, U.1    Wingertszahn, J.2    Wiedow, O.3
  • 114
    • 0042807352 scopus 로고    scopus 로고
    • Targeting the A3 adenosine receptor for cancer therapy: Inhibition of prostate carcinoma cell growth by A3AR agonist
    • Fishman P, Bar-Yehuda S, Ardon E, Rath-Wolfson L, Barrer F, Ochaion A, et al. Targeting the A3 adenosine receptor for cancer therapy: Inhibition of prostate carcinoma cell growth by A3AR agonist. Anticancer Res 2003; 23: 2077-83.
    • (2003) Anticancer Res , vol.23 , pp. 2077-2083
    • Fishman, P.1    Bar-Yehuda, S.2    Ardon, E.3    Rath-Wolfson, L.4    Barrer, F.5    Ochaion, A.6
  • 116
    • 0037030495 scopus 로고    scopus 로고
    • Evidence for involvement of Wnt signaling pathway in IB-MECA mediated suppression of melanoma cells
    • Fishman P, Madi L, Bar-Yehuda S, Barer F, Del Valle L, Khalili K. Evidence for involvement of Wnt signaling pathway in IB-MECA mediated suppression of melanoma cells. Oncogene 2002; 21: 4060-4.
    • (2002) Oncogene , vol.21 , pp. 4060-4064
    • Fishman, P.1    Madi, L.2    Bar-Yehuda, S.3    Barer, F.4    del Valle, L.5    Khalili, K.6
  • 117
    • 70449564383 scopus 로고    scopus 로고
    • The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis
    • Fishman P, Bar-Yehuda S, Madi L, Rath-Wolfson L, Ochaion A, Cohen S, et al. The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis. Arthritis Res Ther 2006; 8: R33.
    • (2006) Arthritis Res Ther , vol.8
    • Fishman, P.1    Bar-Yehuda, S.2    Madi, L.3    Rath-Wolfson, L.4    Ochaion, A.5    Cohen, S.6
  • 118
    • 15044343787 scopus 로고    scopus 로고
    • Antiinflammatory effect of A3 adenosine receptor agonists in murine autoimmune arthritis models
    • Baharav E, Bar-Yehuda S, Madi L, Silberman D, Rath-Wolfson L, Halpren M, et al. Antiinflammatory effect of A3 adenosine receptor agonists in murine autoimmune arthritis models. J Rheumatol 2005; 32: 469-76.
    • (2005) J Rheumatol , vol.32 , pp. 469-476
    • Baharav, E.1    Bar-Yehuda, S.2    Madi, L.3    Silberman, D.4    Rath-Wolfson, L.5    Halpren, M.6
  • 121
    • 79953845021 scopus 로고    scopus 로고
    • Multi-step usage of in vivo models during rational drug desing and discovery
    • Williams CH, Hong CC. Multi-step usage of in vivo models during rational drug desing and discovery. Int J Mol Sci 2011; 12: 2262-74.
    • (2011) Int J Mol Sci , vol.12 , pp. 226-227
    • Williams, C.H.1    Hong, C.C.2
  • 122
    • 36148941061 scopus 로고    scopus 로고
    • Psoriasis: Evolution of pathogenic concepts and new therapies through phases of translational research
    • Guttman-Yassky E, Krueger JG. Psoriasis: Evolution of pathogenic concepts and new therapies through phases of translational research. Br J Dermatol 2007; 157: 1103-15.
    • (2007) Br J Dermatol , vol.157 , pp. 1103-1115
    • Guttman-Yassky, E.1    Krueger, J.G.2
  • 123
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
    • Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework. Clin Pharmacol Ther 2001; 69: 89-95.
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 89-95
  • 124
    • 0035037328 scopus 로고    scopus 로고
    • Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: Criteria, validation, strategies
    • Lesko LJ, Atkinson AJ, Jr. Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: Criteria, validation, strategies. Annu Rev Pharmacol Toxicol 2001; 41: 347-66.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 347-366
    • Lesko, L.J.1    Atkinson Jr., A.J.2
  • 125
    • 68249155540 scopus 로고    scopus 로고
    • A comprehensive review of biomarkers in psoriasis
    • Rashmi R, Rao KS, Basavaraj KH. A comprehensive review of biomarkers in psoriasis. Clin Exp Dermatol 2009; 34: 658-63.
    • (2009) Clin Exp Dermatol , vol.34 , pp. 658-663
    • Rashmi, R.1    Rao, K.S.2    Basavaraj, K.H.3
  • 126
    • 47349119414 scopus 로고    scopus 로고
    • Biological biomarkers in psoriatic disease. A review
    • de Vlam K, Gottlieb AB, Fitzgerald O. Biological biomarkers in psoriatic disease. A review. J Rheumatol 2008; 35: 1443-8.
    • (2008) J Rheumatol , vol.35 , pp. 1443-1448
    • de Vlam, K.1    Gottlieb, A.B.2    Fitzgerald, O.3
  • 127
    • 1342303482 scopus 로고    scopus 로고
    • Of mice and not men: Differences between mouse and human immunology
    • Mestas J, Hughes CC. Of mice and not men: Differences between mouse and human immunology. J Immunol 2004; 172: 2731-8.
    • (2004) J Immunol , vol.172 , pp. 2731-2738
    • Mestas, J.1    Hughes, C.C.2
  • 130
    • 47949117666 scopus 로고    scopus 로고
    • Animal models of psoriasis: A critical appraisal
    • Schon MP. Animal models of psoriasis: A critical appraisal. Exp Dermatol 2008; 17: 703-12.
    • (2008) Exp Dermatol , vol.17 , pp. 703-712
    • Schon, M.P.1
  • 131
  • 132
    • 0033233456 scopus 로고    scopus 로고
    • 1Alpha, 25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice
    • Dam TN, Kang S, Nickoloff BJ, Voorhees JJ. 1Alpha, 25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice. J Invest Dermatol 1999; 113: 1082-9.
    • (1999) J Invest Dermatol , vol.113 , pp. 1082-1089
    • Dam, T.N.1    Kang, S.2    Nickoloff, B.J.3    Voorhees, J.J.4
  • 133
    • 33747082635 scopus 로고    scopus 로고
    • In vivo pharmacological disease models for psoriasis and atopic dermatitis in drug discovery
    • Petersen TK. In vivo pharmacological disease models for psoriasis and atopic dermatitis in drug discovery. Basic Clin Pharmacol Toxicol 2006; 99: 104-15.
    • (2006) Basic Clin Pharmacol Toxicol , vol.99 , pp. 104-115
    • Petersen, T.K.1
  • 135
    • 32644443879 scopus 로고    scopus 로고
    • The psoriasis SCID mouse model: A tool for drug discovery?
    • Boehncke WH. The psoriasis SCID mouse model: a tool for drug discovery? Ernst Schering Res Found Workshop 2005: 213-34.
    • (2005) Ernst Schering Res Found Workshop , pp. 213-234
    • Boehncke, W.H.1
  • 137
    • 34547758019 scopus 로고    scopus 로고
    • Successful treatment of severe refractory atopic dermatitis with efalizumab
    • Farshidi A, Sadeghi P. Successful treatment of severe refractory atopic dermatitis with efalizumab. J Drugs Dermatol 2006; 5: 994-8.
    • (2006) J Drugs Dermatol , vol.5 , pp. 994-998
    • Farshidi, A.1    Sadeghi, P.2
  • 138
    • 34548852889 scopus 로고    scopus 로고
    • Balancing the benefits and risks of drug treatment: A stated-preference, discrete choice experiment with patients with psoriasis
    • Seston EM, Ashcroft DM, Griffiths CE. Balancing the benefits and risks of drug treatment: A stated-preference, discrete choice experiment with patients with psoriasis. Arch Dermatol 2007; 143: 1175-9.
    • (2007) Arch Dermatol , vol.143 , pp. 1175-1179
    • Seston, E.M.1    Ashcroft, D.M.2    Griffiths, C.E.3
  • 139
    • 34250030209 scopus 로고    scopus 로고
    • Patients with moderate-to-severe plaque psoriasis preferred oral therapies to phototherapies: A preference assessment based on clinical scenarios with trade-off questions
    • Opmeer BC, Heydendael VM, deBorgie CA, Spuls PI, Bossuyt PM, Bos JD, et al. Patients with moderate-to-severe plaque psoriasis preferred oral therapies to phototherapies: A preference assessment based on clinical scenarios with trade-off questions. J Clin Epidemiol 2007; 60: 696-703.
    • (2007) J Clin Epidemiol , vol.60 , pp. 696-703
    • Opmeer, B.C.1    Heydendael, V.M.2    deBorgie, C.A.3    Spuls, P.I.4    Bossuyt, P.M.5    Bos, J.D.6
  • 140
    • 0035977920 scopus 로고    scopus 로고
    • Assessment of biotechnology products for therapeutic use
    • Sims J. Assessment of biotechnology products for therapeutic use. Toxicol Lett 2001; 120: 59-63.
    • (2001) Toxicol Lett , vol.120 , pp. 59-63
    • Sims, J.1
  • 141
    • 0036346347 scopus 로고    scopus 로고
    • Enhanced fibroblast contraction of 3D collagen lattices and integrin expression by TGF-beta1 and-beta3: Mechanoregulatory growth factors?
    • Brown RA, Sethi KK, Gwanmesia I, Raemdonck D, Eastwood M, Mudera V. Enhanced fibroblast contraction of 3D collagen lattices and integrin expression by TGF-beta1 and-beta3: Mechanoregulatory growth factors? Exp Cell Res 2002; 274: 310-22.
    • (2002) Exp Cell Res , vol.274 , pp. 310-322
    • Brown, R.A.1    Sethi, K.K.2    Gwanmesia, I.3    Raemdonck, D.4    Eastwood, M.5    Mudera, V.6
  • 142
    • 84855831905 scopus 로고    scopus 로고
    • Center for Biologics Evaluation and Research. Available at, (Accessed on: October 1, 2011)
    • ICH Harmonized Tripartite Guideline. Safety evaluation of biotechnology derived pharmaceuticals S6 (R1). Center for Biologics Evaluation and Research. Available at: http: //www.ich.org/ fileadmin/Public_Web_Site/ICH_Products / Guidelines/ Safety/S6_R1/Step4/S6_R1_Guideline.pdf. (Accessed on: October 1, 2011).
    • ICH Harmonized Tripartite Guideline. Safety evaluation of biotechnology derived pharmaceuticals S6 (R1)
  • 143
    • 0033024643 scopus 로고    scopus 로고
    • Safety assessment of biotechnologyderived pharmaceuticals: ICH and beyond
    • Serabian MA, Pilaro AM. Safety assessment of biotechnologyderived pharmaceuticals: ICH and beyond. Toxicol Pathol 1999; 27: 27-31.
    • (1999) Toxicol Pathol , vol.27 , pp. 27-31
    • Serabian, M.A.1    Pilaro, A.M.2
  • 144
    • 0034167943 scopus 로고    scopus 로고
    • Safety evaluation of immunomodulatory biopharmaceuticals: Can we improve the predictive value of preclinical studies?
    • Black LE, Green JD, Rener J, Dayan A, Cavagnaro JA, Spindler P, et al. Safety evaluation of immunomodulatory biopharmaceuticals: Can we improve the predictive value of preclinical studies? Hum Exp Toxicol 2000; 19: 205-7.
    • (2000) Hum Exp Toxicol , vol.19 , pp. 205-207
    • Black, L.E.1    Green, J.D.2    Rener, J.3    Dayan, A.4    Cavagnaro, J.A.5    Spindler, P.6
  • 145
    • 0036593951 scopus 로고    scopus 로고
    • Preclinical safety evaluation of biotechnologyderived pharmaceuticals
    • Cavagnaro JA. Preclinical safety evaluation of biotechnologyderived pharmaceuticals. Nat Rev Drug Discov 2002; 1: 469-75.
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 469-475
    • Cavagnaro, J.A.1
  • 146
    • 33750536288 scopus 로고    scopus 로고
    • European Medicines Agency. Committee for medicinal products for human use, Available at, (Accesed on: October 1, 2011)
    • European Medicines Agency. Committee for medicinal products for human use. Guideline on clinical investigation of medicinal products indicated for the treatment of psoriasis. Available at http: //www.ema.europa.eu/docs/en_GB/document_library/Scientific_gu ideline/2009/09/WC500003329.pdf (Accesed on: October 1, 2011)
    • Guideline on clinical investigation of medicinal products indicated for the treatment of psoriasis
  • 147
    • 49849101640 scopus 로고    scopus 로고
    • Options for the treatment of psoriasis: A multifactorial approach
    • van de Kerkhof PC. Options for the treatment of psoriasis: A multifactorial approach. Clin Dermatol 2008; 26: 419-23.
    • (2008) Clin Dermatol , vol.26 , pp. 419-423
    • van de Kerkhof, P.C.1
  • 148
    • 34249826335 scopus 로고    scopus 로고
    • Novel insight into the agonistic mechanism of alefacept in vivo: Differentially expressed genes may serve as biomarkers of response in psoriasis patients
    • Haider AS, Lowes MA, Gardner H, Bandaru R, Darabi K, Chamian F, et al. Novel insight into the agonistic mechanism of alefacept in vivo: Differentially expressed genes may serve as biomarkers of response in psoriasis patients. J Immunol 2007; 178: 7442-9.
    • (2007) J Immunol , vol.178 , pp. 7442-7449
    • Haider, A.S.1    Lowes, M.A.2    Gardner, H.3    Bandaru, R.4    Darabi, K.5    Chamian, F.6
  • 149
    • 49849098802 scopus 로고    scopus 로고
    • Future perspectives/quo vadis psoriasis treatment? Immunology, pharmacogenomics, and epidemiology
    • Kimball AB, Kupper TS. Future perspectives/quo vadis psoriasis treatment? Immunology, pharmacogenomics, and epidemiology. Clin Dermatol 2008; 26: 554-61.
    • (2008) Clin Dermatol , vol.26 , pp. 554-561
    • Kimball, A.B.1    Kupper, T.S.2
  • 150
    • 84860390352 scopus 로고    scopus 로고
    • Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis
    • Marrakchi S, Guigue P, Renshaw BR, Puel A, Pei XY, Fraitag S, et al. Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis. N Engl J Med 2011; 365: 620-8.
    • (2011) N Engl J Med , vol.365 , pp. 620-628
    • Marrakchi, S.1    Guigue, P.2    Renshaw, B.R.3    Puel, A.4    Pei, X.Y.5    Fraitag, S.6
  • 151
    • 0030059492 scopus 로고    scopus 로고
    • Proceedings of the Psoriasis Combination and Rotation Therapy Conference
    • Deer Valley, Utah, Oct, 7-9, 1994
    • Menter MA, See JA, Amend WJ, Ellis CN, Krueger GG, Lebwohl M, et al. Proceedings of the Psoriasis Combination and Rotation Therapy Conference. Deer Valley, Utah, Oct. 7-9, 1994. J Am Acad Dermatol 1996; 34: 315-21.
    • (1996) J Am Acad Dermatol , vol.34 , pp. 315-321
    • Menter, M.A.1    See, J.A.2    Amend, W.J.3    Ellis, C.N.4    Krueger, G.G.5    Lebwohl, M.6
  • 153
    • 0036348583 scopus 로고    scopus 로고
    • Pediatric psoriasis revisited
    • Marcoux D, Prost Y. Pediatric psoriasis revisited. J Cutan Med Surg 2002; 6: 22-8.
    • (2002) J Cutan Med Surg , vol.6 , pp. 22-28
    • Marcoux, D.1    Prost, Y.2
  • 155
    • 0025830166 scopus 로고
    • Halobetasol propionate cream by day and halobetasol propionate ointment at night for the treatment of pediatric patients with chronic, localized plaque psoriasis and atopic dermatitis
    • Herz G, Blum G, Yawalkar S. Halobetasol propionate cream by day and halobetasol propionate ointment at night for the treatment of pediatric patients with chronic, localized plaque psoriasis and atopic dermatitis. J Am Acad Dermatol 1991; 25: 1166-9.
    • (1991) J Am Acad Dermatol , vol.25 , pp. 1166-1169
    • Herz, G.1    Blum, G.2    Yawalkar, S.3
  • 156
    • 0036851496 scopus 로고    scopus 로고
    • Influence of microemulsions on cutaneous drug delivery
    • Kreilgaard M. Influence of microemulsions on cutaneous drug delivery. Adv Drug Deliv Rev 2002; 54 (Suppl 1): S77-98.
    • (2002) Adv Drug Deliv Rev , vol.54 , Issue.SUPPL. 1
    • Kreilgaard, M.1
  • 157
  • 158
    • 1842663219 scopus 로고    scopus 로고
    • Increased risk for cardiovascular mortality in psoriasis inpatients but not in outpatients
    • Mallbris L, Akre O, Granath F, Yin L, Lindelof B, Ekbom A, et al. Increased risk for cardiovascular mortality in psoriasis inpatients but not in outpatients. Eur J Epidemiol 2004; 19: 225-30.
    • (2004) Eur J Epidemiol , vol.19 , pp. 225-230
    • Mallbris, L.1    Akre, O.2    Granath, F.3    Yin, L.4    Lindelof, B.5    Ekbom, A.6
  • 160
    • 67449162065 scopus 로고    scopus 로고
    • Psoriasis and osteoporosis: A sex-specific association?
    • Dreiher J, Weitzman D, Cohen AD. Psoriasis and osteoporosis: A sex-specific association? J Invest Dermatol 2009; 129: 1643-9.
    • (2009) J Invest Dermatol , vol.129 , pp. 1643-1649
    • Dreiher, J.1    Weitzman, D.2    Cohen, A.D.3
  • 161
  • 162
    • 67449136390 scopus 로고    scopus 로고
    • Complexity of the association between psoriasis and comorbidities
    • Nijsten T, Wakkee M. Complexity of the association between psoriasis and comorbidities. J Invest Dermatol 2009; 129: 1601-3.
    • (2009) J Invest Dermatol , vol.129 , pp. 1601-1603
    • Nijsten, T.1    Wakkee, M.2
  • 163
    • 67649659930 scopus 로고    scopus 로고
    • A series of critically challenging case scenarios in moderate to severe psoriasis: A Delphi consensus approach
    • Strober B, Berger E, Cather J, Cohen D, Crowley JJ, Gordon KB, et al. A series of critically challenging case scenarios in moderate to severe psoriasis: A Delphi consensus approach. J Am Acad Dermatol 2009; 61: S1-46.
    • (2009) J Am Acad Dermatol , vol.61
    • Strober, B.1    Berger, E.2    Cather, J.3    Cohen, D.4    Crowley, J.J.5    Gordon, K.B.6
  • 164
    • 0346218047 scopus 로고    scopus 로고
    • Medication formulation affects quality of life: A randomized single-blind study of clobetasol propionate foam 0.05% compared with a combined program of clobetasol cream 0.05% and solution 0.05% for the treatment of psoriasis
    • Bergstrom KG, Arambula K, Kimball AB. Medication formulation affects quality of life: A randomized single-blind study of clobetasol propionate foam 0.05% compared with a combined program of clobetasol cream 0.05% and solution 0.05% for the treatment of psoriasis. Cutis 2003; 72: 407-11.
    • (2003) Cutis , vol.72 , pp. 407-411
    • Bergstrom, K.G.1    Arambula, K.2    Kimball, A.B.3
  • 165
    • 23844524231 scopus 로고    scopus 로고
    • Clobetasol propionate foam in the treatment of psoriasis
    • Reid DC, Kimball AB. Clobetasol propionate foam in the treatment of psoriasis. Expert Opin Pharmacother 2005; 6: 1735-40.
    • (2005) Expert Opin Pharmacother , vol.6 , pp. 1735-1740
    • Reid, D.C.1    Kimball, A.B.2
  • 166
    • 57549084477 scopus 로고    scopus 로고
    • Development of an in vitro psoriatic skin model by tissue engineering
    • Jean J, Lapointe M, Soucy J, Pouliot R. Development of an in vitro psoriatic skin model by tissue engineering. J Dermatol Sci 2009; 53: 19-25.
    • (2009) J Dermatol Sci , vol.53 , pp. 19-25
    • Jean, J.1    Lapointe, M.2    Soucy, J.3    Pouliot, R.4
  • 167
    • 79959562516 scopus 로고    scopus 로고
    • Effects of retinoic acid on keratinocyte proliferation and differentiation in a psoriatic skin model
    • Jean J, Soucy J, Pouliot R. Effects of retinoic acid on keratinocyte proliferation and differentiation in a psoriatic skin model. Tissue Eng Part A 2011; 17: 1859-68.
    • (2011) Tissue Eng Part A , vol.17 , pp. 1859-1868
    • Jean, J.1    Soucy, J.2    Pouliot, R.3
  • 169
    • 70350491054 scopus 로고    scopus 로고
    • Retinoids, methotrexate and cyclosporine
    • Dubertret L. Retinoids, methotrexate and cyclosporine. Curr Probl Dermatol 2009; 38: 79-94.
    • (2009) Curr Probl Dermatol , vol.38 , pp. 79-94
    • Dubertret, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.