Low pH-Induced pore formation by the T domain of botulinum toxin type A is dependent upon NaCl concentration

Journal of Membrane Biology

Volumn 236, Issue 2, 2010, Pages 191-201

  Lai, Bing ^a   Agarwal, Rakhi ^b   Nelson, Lindsay D ^a   Swaminathan, Subramanyam ^b   London, Erwin ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

Lipid protein interaction; Membrane biophysics; Membrane protein; Protein toxin

Indexed keywords

BOTULINUM TOXIN A; DETERGENT; DIOLEOYLPHOSPHATIDYLCHOLINE; DIOLEOYLPHOSPHATIDYLGLYCEROL; DODECYLMALTOSIDE; LIPID; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ALKALINITY; AQUEOUS SOLUTION; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; MEMBRANE VESICLE; NONHUMAN; PH; PROTEIN INTERACTION; STATIC ELECTRICITY; TRANSLOCATION LINE;

BOTULINUM TOXINS, TYPE A; CIRCULAR DICHROISM; HYDROGEN-ION CONCENTRATION; LIPIDS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SODIUM CHLORIDE;

EID: 78650214996     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-010-9292-z     Document Type: Article

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