Functional proteomic and structural insights into molecular targets related to the growth inhibitory effect of tanshinone IIA on HeLa cells

Proteomics

Volumn 10, Issue 5, 2010, Pages 914-929

  Pan, Tai Long ^a   Hung, Yu Chiang ^a,b   Wang, Pei Wen ^a   Chen, Shui Ten ^c   Hsu, Teng Kuei ^c   Sintupisut, Nardnisa ^c   Cheng, Chao Sheng ^d   Lyu, Ping Chiang ^d  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^d NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

2 DE; Apoptosis; Cell biology; HeLa cell; MALDI TOF analysis; MetaCore ; Tanshinone IIA

Indexed keywords

ALPHA TUBULIN; ANTINEOPLASTIC AGENT; BETA TUBULIN; CYTOSKELETON PROTEIN; HEAT SHOCK PROTEIN; MASPIN; MICROTUBULE PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P53; TANSHINONE IIA; VIMENTIN;

AMINO ACID SEQUENCE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BETA CHAIN; BIOINFORMATICS; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CYTOTOXICITY; DNA DEGRADATION; DNA FRAGMENTATION; DRUG EFFECT; DRUG ISOLATION; DRUG POTENCY; FLOW CYTOMETRY; FUNCTIONAL PROTEOMICS; HELA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MICROTUBULE ASSEMBLY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION; SALVIA MILTIORRHIZA; UTERINE CERVIX CANCER; WESTERN BLOTTING;

CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FLUORESCENT ANTIBODY TECHNIQUE; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MICROTUBULES; MODELS, MOLECULAR; PEPTIDE MAPPING; PHENANTHRENES; POLY(ADP-RIBOSE) POLYMERASES; PROTEOME; PROTEOMICS; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TIME FACTORS; VIMENTIN;

SALVIA MILTIORRHIZA;

EID: 77649169304     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200900178     Document Type: Article

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