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Volumn 4, Issue SPEC. ISSUE 1, 2011, Pages 39-47

Wharton's jelly stem cells as agents for cancer therapy

Author keywords

Cytotherapy; Immunogenicity; Tumor homing; Tumor tissue tropism; Umbilical cord matrix stem cell; Wharto s jelly

Indexed keywords

BETA INTERFERON; B7 ANTIGEN; CD86 ANTIGEN; CYTOKINE; GROWTH FACTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NANOPARTICLE; PLASMID DNA; PROSTAGLANDIN E2; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84855760637     PISSN: None     EISSN: 18750435     Source Type: Journal    
DOI: 10.2174/1875043501104010039     Document Type: Review
Times cited : (26)

References (61)
  • 1
    • 0032504070 scopus 로고    scopus 로고
    • Study on myofibroblast differentiation in the stromal cells of Wharton's jelly: Expression and localization of alpha-smooth muscle actin
    • Kobayashi K, Kubota T, Aso T. Study on myofibroblast differentiation in the stromal cells of Wharton's jelly: expression and localization of alpha-smooth muscle actin. Early Hum Dev 1998; 51: 223-33.
    • (1998) Early Hum Dev , vol.51 , pp. 223-233
    • Kobayashi, K.1    Kubota, T.2    Aso, T.3
  • 3
    • 68049144834 scopus 로고    scopus 로고
    • Novel sources of fetal stem cells: Where do they fit on the developmental continuum?
    • Pappa KI, Anagnou NP. Novel sources of fetal stem cells: where do they fit on the developmental continuum? Regen Med 2009; 4: 423-33.
    • (2009) Regen Med , vol.4 , pp. 423-433
    • Pappa, K.I.1    Anagnou, N.P.2
  • 4
    • 33144484386 scopus 로고    scopus 로고
    • Expression of early transcription factors Oct4, Sox2 and Nanog by porcine umbilical cord (PUC) matrix cells
    • Carlin R, Davis D, Weiss M, Schultz B, Troyer D. Expression of early transcription factors Oct4, Sox2 and Nanog by porcine umbilical cord (PUC) matrix cells. Reprod Biol Endocrinol 2006; 4: 8.
    • (2006) Reprod Biol Endocrinol , vol.4 , pp. 8
    • Carlin, R.1    Davis, D.2    Weiss, M.3    Schultz, B.4    Troyer, D.5
  • 5
    • 58149330600 scopus 로고    scopus 로고
    • + mesenchymal stem cells from human umbilical cord matrix: Differentiation potential and detection of new markers
    • + mesenchymal stem cells from human umbilical cord matrix: differentiation potential and detection of new markers. Histochem Cell Biol 2009; 131: 267-82.
    • (2009) Histochem Cell Biol , vol.131 , pp. 267-282
    • la Rocca, G.1    Anzalone, R.2    Corrao, S.3
  • 6
    • 0037237389 scopus 로고    scopus 로고
    • Matrix cells from Wharton's jelly form neurons and glia
    • Mitchell KE, Weiss ML, Mitchell BM, et al. Matrix cells from Wharton's jelly form neurons and glia. Stem Cells 2003; 21: 50-60.
    • (2003) Stem Cells , vol.21 , pp. 50-60
    • Mitchell, K.E.1    Weiss, M.L.2    Mitchell, B.M.3
  • 7
    • 10444248938 scopus 로고    scopus 로고
    • Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord
    • Wang HS, Hung SC, Peng ST, et al. Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord. Stem Cells 2004; 22: 1330-7.
    • (2004) Stem Cells , vol.22 , pp. 1330-1337
    • Wang, H.S.1    Hung, S.C.2    Peng, S.T.3
  • 8
    • 34948896045 scopus 로고    scopus 로고
    • Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
    • Karnoub AE, Dash AB, Vo AP, et al. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 2007; 449: 557-63.
    • (2007) Nature , vol.449 , pp. 557-563
    • Karnoub, A.E.1    Dash, A.B.2    Vo, A.P.3
  • 9
    • 46749142540 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from human adipose tissues favor tumor cell growth in vivo
    • Yu JM, Jun ES, Bae YC, Jung JS. Mesenchymal stem cells derived from human adipose tissues favor tumor cell growth in vivo. Stem Cells Dev 2008; 17: 463-73.
    • (2008) Stem Cells Dev , vol.17 , pp. 463-473
    • Yu, J.M.1    Jun, E.S.2    Bae, Y.C.3    Jung, J.S.4
  • 10
    • 42249110515 scopus 로고    scopus 로고
    • Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favor early tumor growth in syngeneic mice
    • Galiè M, Konstantinidou G, Peroni D, et al. Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favor early tumor growth in syngeneic mice. Oncogene 2008; 27: 2542-51.
    • (2008) Oncogene , vol.27 , pp. 2542-2551
    • Galiè, M.1    Konstantinidou, G.2    Peroni, D.3
  • 11
    • 38649105374 scopus 로고    scopus 로고
    • Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
    • Ren G, Zhang L, Zhao X, et al. Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2008; 2: 141-50.
    • (2008) Cell Stem Cell , vol.2 , pp. 141-150
    • Ren, G.1    Zhang, L.2    Zhao, X.3
  • 12
    • 1642373909 scopus 로고    scopus 로고
    • Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms
    • Kinnaird T, Stabile E, Burnett MS, et al. Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ Res 2004; 94: 678-85.
    • (2004) Circ Res , vol.94 , pp. 678-685
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3
  • 13
    • 78649320264 scopus 로고    scopus 로고
    • Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: Stimulation of epithelial to mesenchymal transition (EMT)
    • Martin FT, Dwyer RM, Kelly J, et al. Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT). Breast Cancer Res Treat 2010; 124: 317-26.
    • (2010) Breast Cancer Res Treat , vol.124 , pp. 317-326
    • Martin, F.T.1    Dwyer, R.M.2    Kelly, J.3
  • 14
    • 0242410394 scopus 로고    scopus 로고
    • Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
    • Djouad F, Plence P, Bony C, et al. Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood 2003; 102: 3837-44.
    • (2003) Blood , vol.102 , pp. 3837-3844
    • Djouad, F.1    Plence, P.2    Bony, C.3
  • 15
    • 33646690027 scopus 로고    scopus 로고
    • Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma
    • Khakoo AY, Pati S, Anderson SA, et al. Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma. J Exp Med 2006; 203: 1235-47.
    • (2006) J Exp Med , vol.203 , pp. 1235-1247
    • Khakoo, A.Y.1    Pati, S.2    Anderson, S.A.3
  • 16
    • 53749086196 scopus 로고    scopus 로고
    • Transplantation of human umbilical mesenchymal stem cells from Wharton's jelly after complete transection of the rat spinal cord
    • Yang CC, Shih YH, Ko MH, et al. Transplantation of human umbilical mesenchymal stem cells from Wharton's jelly after complete transection of the rat spinal cord. PLoS One 2008; 3: e3336.
    • (2008) PLoS One , vol.3
    • Yang, C.C.1    Shih, Y.H.2    Ko, M.H.3
  • 17
    • 79953794756 scopus 로고    scopus 로고
    • VEGF-expressing human umbilical cord mesenchymal stem cells, an improved therapy strategy for Parkinson's disease
    • Xiong N, Zhang Z, Huang J, et al. VEGF-expressing human umbilical cord mesenchymal stem cells, an improved therapy strategy for Parkinson's disease. Gene Ther 2010; 18: 394-402.
    • (2010) Gene Ther , vol.18 , pp. 394-402
    • Xiong, N.1    Zhang, Z.2    Huang, J.3
  • 18
    • 39049164672 scopus 로고    scopus 로고
    • Islet-like clusters derived from mesenchymal stem cells in Wharton's Jelly of the human umbilical cord for transplantation to control type 1 diabetes
    • Chao KC, Chao KF, Fu YS, Liu SH. Islet-like clusters derived from mesenchymal stem cells in Wharton's Jelly of the human umbilical cord for transplantation to control type 1 diabetes. PLoS ONE 2008; 3: e1451.
    • (2008) PLoS ONE , vol.3
    • Chao, K.C.1    Chao, K.F.2    Fu, Y.S.3    Liu, S.H.4
  • 19
    • 48249135508 scopus 로고    scopus 로고
    • Combination treatment of human umbilical cord matrix stem cell-based interferon-beta gene therapy and 5-fluorouracil significantly reduces growth of metastatic human breast cancer in SCID mouse lungs
    • Rachakatla RS, Pyle MM, Ayuzawa R, et al. Combination treatment of human umbilical cord matrix stem cell-based interferon-beta gene therapy and 5-fluorouracil significantly reduces growth of metastatic human breast cancer in SCID mouse lungs. Cancer Invest 2008; 26: 662-70.
    • (2008) Cancer Invest , vol.26 , pp. 662-670
    • Rachakatla, R.S.1    Pyle, M.M.2    Ayuzawa, R.3
  • 20
    • 77949308137 scopus 로고    scopus 로고
    • Proinflammatory cytokines, IFNgamma and TNFalpha, influence immune properties of human bone marrow and Wharton jelly mesenchymal stem cells differentially
    • Prasanna SJ, Gopalakrishnan D, Shankar SR, Vasandan AB. Proinflammatory cytokines, IFNgamma and TNFalpha, influence immune properties of human bone marrow and Wharton jelly mesenchymal stem cells differentially. PLoS One 2010; 5: e9016.
    • (2010) PLoS One , vol.5
    • Prasanna, S.J.1    Gopalakrishnan, D.2    Shankar, S.R.3    Vasandan, A.B.4
  • 21
    • 56249139741 scopus 로고    scopus 로고
    • Immune properties of human umbilical cord Wharton's jelly-derived cells
    • Weiss ML, Anderson C, Medicetty S, et al. Immune properties of human umbilical cord Wharton's jelly-derived cells. Stem Cells 2008; 26: 2865-74.
    • (2008) Stem Cells , vol.26 , pp. 2865-2874
    • Weiss, M.L.1    Anderson, C.2    Medicetty, S.3
  • 22
    • 80052098824 scopus 로고    scopus 로고
    • Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cells
    • Deuse T, Stubbendorff M, Tang-Quan K, et al. Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cells. Cell Transplant 2010.
    • (2010) Cell Transplant
    • Deuse, T.1    Stubbendorff, M.2    Tang-Quan, K.3
  • 23
    • 38349053355 scopus 로고    scopus 로고
    • Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells
    • Selmani Z, Naji A, Zidi I, et al. Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells. Stem Cells 2008; 26: 212-22.
    • (2008) Stem Cells , vol.26 , pp. 212-222
    • Selmani, Z.1    Naji, A.2    Zidi, I.3
  • 24
    • 78649374199 scopus 로고    scopus 로고
    • Immunological aspects of allogeneic mesenchymal stem cell therapies
    • Griffin MD, Ritter T, Mahon BP. Immunological aspects of allogeneic mesenchymal stem cell therapies. Hum Gene Ther 2010; 21: 1641-55.
    • (2010) Hum Gene Ther , vol.21 , pp. 1641-1655
    • Griffin, M.D.1    Ritter, T.2    Mahon, B.P.3
  • 25
    • 78650673843 scopus 로고    scopus 로고
    • Umbilical cord-derived mesenchymal stromal cells modulate monocyte function to suppress T cell proliferation
    • Cutler AJ, Limbani V, Girdlestone J, Navarrete CV. Umbilical cord-derived mesenchymal stromal cells modulate monocyte function to suppress T cell proliferation. J Immunol 2010; 185: 6617-23.
    • (2010) J Immunol , vol.185 , pp. 6617-6623
    • Cutler, A.J.1    Limbani, V.2    Girdlestone, J.3    Navarrete, C.V.4
  • 26
    • 77955054854 scopus 로고    scopus 로고
    • CD14+ monocytes promote the immunosuppressive effect of human umbilical cord matrix stem cells
    • Wang D, Chen K, Du WT, et al. CD14+ monocytes promote the immunosuppressive effect of human umbilical cord matrix stem cells. Exp Cell Res 2010; 316: 2414-23.
    • (2010) Exp Cell Res , vol.316 , pp. 2414-2423
    • Wang, D.1    Chen, K.2    Du, W.T.3
  • 27
    • 33846933759 scopus 로고    scopus 로고
    • Chondrogenic differentiation alters the immunosuppressive property of bone marrow-derived mesenchymal stem cells, and the effect is partially due to the upregulated expression of B7 molecules
    • Chen X, McClurg A, Zhou GQ, et al. Chondrogenic differentiation alters the immunosuppressive property of bone marrow-derived mesenchymal stem cells, and the effect is partially due to the upregulated expression of B7 molecules. Stem Cells 2007; 25: 364-70.
    • (2007) Stem Cells , vol.25 , pp. 364-370
    • Chen, X.1    McClurg, A.2    Zhou, G.Q.3
  • 28
    • 0034619328 scopus 로고    scopus 로고
    • Neural stem cells display extensive tropism for pathology in adult brain: Evidence from intracranial gliomas
    • Aboody KS, Brown A, Rainov NG, et al. Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc Natl Acad Sci U S A 2000; 97: 12846-51.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 12846-12851
    • Aboody, K.S.1    Brown, A.2    Rainov, N.G.3
  • 29
    • 0036644833 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors
    • Studeny M, Marini FC, Champlin RE, et al. Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors. Cancer Res 2002; 62: 3603-8.
    • (2002) Cancer Res , vol.62 , pp. 3603-3608
    • Studeny, M.1    Marini, F.C.2    Champlin, R.E.3
  • 30
    • 7944220831 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agents
    • Studeny M, Marini FC, Dembinski JL, et al. Mesenchymal stem cells: potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agents. J Natl Cancer Inst 2004; 96: 1593-603.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1593-1603
    • Studeny, M.1    Marini, F.C.2    Dembinski, J.L.3
  • 31
    • 20244374417 scopus 로고    scopus 로고
    • Human bone marrowderived mesenchymal stem cells in the treatment of gliomas
    • Nakamizo A, Marini F, Amano T, et al. Human bone marrowderived mesenchymal stem cells in the treatment of gliomas. Cancer Res 2005; 65: 3307-18.
    • (2005) Cancer Res , vol.65 , pp. 3307-3318
    • Nakamizo, A.1    Marini, F.2    Amano, T.3
  • 32
    • 67349163717 scopus 로고    scopus 로고
    • Naive human umbilical cord matrix derived stem cells significantly attenuate growth of human breast cancer cells in vitro and in vivo
    • Ayuzawa R, Doi C, Rachakatla RS, et al. Naive human umbilical cord matrix derived stem cells significantly attenuate growth of human breast cancer cells in vitro and in vivo. Cancer Lett 2009; 280: 31-7.
    • (2009) Cancer Lett , vol.280 , pp. 31-37
    • Ayuzawa, R.1    Doi, C.2    Rachakatla, R.S.3
  • 33
    • 77950568999 scopus 로고    scopus 로고
    • Cytotherapy with naive rat umbilical cord matrix stem cells significantly attenuates growth of murine pancreatic cancer cells and increases survival in syngeneic mice
    • Doi C, Maurya DK, Pyle MM, Troyer D, Tamura M. Cytotherapy with naive rat umbilical cord matrix stem cells significantly attenuates growth of murine pancreatic cancer cells and increases survival in syngeneic mice. Cytotherapy 2010; 12: 408-17.
    • (2010) Cytotherapy , vol.12 , pp. 408-417
    • Doi, C.1    Maurya, D.K.2    Pyle, M.M.3    Troyer, D.4    Tamura, M.5
  • 34
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • Dvorak HF. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 1986; 315: 1650-59.
    • (1986) N Engl J Med , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 35
    • 67349195445 scopus 로고    scopus 로고
    • Human mesenchymal stem cells inhibit cancer cell proliferation by secreting DKK-1
    • Zhu Y, Sun Z, Han Q, et al. Human mesenchymal stem cells inhibit cancer cell proliferation by secreting DKK-1. Leukemia 2009; 23: 925-33.
    • (2009) Leukemia , vol.23 , pp. 925-933
    • Zhu, Y.1    Sun, Z.2    Han, Q.3
  • 36
    • 0035282432 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in breast cancer metastasis
    • Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001; 410: 50-6.
    • (2001) Nature , vol.410 , pp. 50-56
    • Muller, A.1    Homey, B.2    Soto, H.3
  • 37
    • 34547567884 scopus 로고    scopus 로고
    • The participation of mesenchymal stem cells in tumor stroma formation and their application as targeted-gene delivery vehicles
    • Hall B, Andreeff M, Marini F. The participation of mesenchymal stem cells in tumor stroma formation and their application as targeted-gene delivery vehicles. Handb Exp Pharmacol 2007; 263-83.
    • (2007) Handb Exp Pharmacol , pp. 263-283
    • Hall, B.1    Andreeff, M.2    Marini, F.3
  • 38
    • 51349095580 scopus 로고    scopus 로고
    • Detection of migration of locally implanted AC133+ stem cells by cellular magnetic resonance imaging with histological findings
    • Arbab AS, Janic B, Knight RA, et al. Detection of migration of locally implanted AC133+ stem cells by cellular magnetic resonance imaging with histological findings. Faseb J 2008; 22: 3234-46.
    • (2008) Faseb J , vol.22 , pp. 3234-3246
    • Arbab, A.S.1    Janic, B.2    Knight, R.A.3
  • 39
    • 65349149983 scopus 로고    scopus 로고
    • Overexpression of CXC chemokine receptors is required for the superior glioma-tracking property of umbilical cord blood-derived mesenchymal stem cells
    • Kim DS, Kim JH, Lee JK, et al. Overexpression of CXC chemokine receptors is required for the superior glioma-tracking property of umbilical cord blood-derived mesenchymal stem cells. Stem Cells Dev 2009; 18: 511-9.
    • (2009) Stem Cells Dev , vol.18 , pp. 511-519
    • Kim, D.S.1    Kim, J.H.2    Lee, J.K.3
  • 40
    • 78650836835 scopus 로고    scopus 로고
    • CXCR4-transfected human umbilical cord blood-derived mesenchymal stem cells exhibit enhanced migratory capacity toward gliomas
    • Park SA, Ryu CH, Kim SM, et al. CXCR4-transfected human umbilical cord blood-derived mesenchymal stem cells exhibit enhanced migratory capacity toward gliomas. Int J Oncol 2011; 38: 97-103.
    • (2011) Int J Oncol , vol.38 , pp. 97-103
    • Park, S.A.1    Ryu, C.H.2    Kim, S.M.3
  • 41
    • 77953016267 scopus 로고    scopus 로고
    • SDF-1/CXCR4-mediated migration of transplanted bone marrow stromal cells toward areas of heart myocardial infarction through activation of PI3K/Akt
    • Yu J, Li M, Qu Z, et al. SDF-1/CXCR4-mediated migration of transplanted bone marrow stromal cells toward areas of heart myocardial infarction through activation of PI3K/Akt. J Cardiovasc Pharmacol 2010; 55: 496-505.
    • (2010) J Cardiovasc Pharmacol , vol.55 , pp. 496-505
    • Yu, J.1    Li, M.2    Qu, Z.3
  • 42
    • 34548621387 scopus 로고    scopus 로고
    • Development of human umbilical cord matrix stem cell-based gene therapy for experimental lung tumors
    • Rachakatla RS, Marini F, Weiss ML, Tamura M, Troyer D. Development of human umbilical cord matrix stem cell-based gene therapy for experimental lung tumors. Cancer Gene Ther 2007; 14: 828-35.
    • (2007) Cancer Gene Ther , vol.14 , pp. 828-835
    • Rachakatla, R.S.1    Marini, F.2    Weiss, M.L.3    Tamura, M.4    Troyer, D.5
  • 43
    • 0033571747 scopus 로고    scopus 로고
    • Transgenic mice overexpressing protein kinase Cdelta in the epidermis are resistant to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate
    • Reddig PJ, Dreckschmidt N, et al. Transgenic mice overexpressing protein kinase Cdelta in the epidermis are resistant to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Cancer Res 1999; 59: 5710-18.
    • (1999) Cancer Res , vol.59 , pp. 5710-5718
    • Reddig, P.J.1    Dreckschmidt, N.2
  • 44
    • 77949659742 scopus 로고    scopus 로고
    • Reduction of nontarget infection and systemic toxicity by targeted delivery of conditionally replicating viruses transported in mesenchymal stem cells
    • Dembinski JL, Spaeth EL, Fueyo J, et al. Reduction of nontarget infection and systemic toxicity by targeted delivery of conditionally replicating viruses transported in mesenchymal stem cells. Cancer Gene Ther 2009; 17: 289-97.
    • (2009) Cancer Gene Ther , vol.17 , pp. 289-297
    • Dembinski, J.L.1    Spaeth, E.L.2    Fueyo, J.3
  • 45
    • 77956187466 scopus 로고    scopus 로고
    • Human umbilical cord matrix-derived stem cells expressing interferon-beta gene significantly attenuate bronchioloalveolar carcinoma xenografts in SCID mice
    • Matsuzuka T, Rachakatla RS, Doi C, et al. Human umbilical cord matrix-derived stem cells expressing interferon-beta gene significantly attenuate bronchioloalveolar carcinoma xenografts in SCID mice. Lung Cancer 2010; 70: 28-36.
    • (2010) Lung Cancer , vol.70 , pp. 28-36
    • Matsuzuka, T.1    Rachakatla, R.S.2    Doi, C.3
  • 46
    • 77949514437 scopus 로고    scopus 로고
    • Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies
    • Frank RT, Edmiston M, Kendall SE, et al. Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies. PLoS One 2009; 4: e8314.
    • (2009) PLoS One , vol.4
    • Frank, R.T.1    Edmiston, M.2    Kendall, S.E.3
  • 47
    • 77957660560 scopus 로고    scopus 로고
    • Therapeutic targeting of melanoma cells using neural stem cells expressing carboxylesterase, a CPT-11 activating enzyme
    • Gutova M, Najbauer J, Chen MY, et al. Therapeutic targeting of melanoma cells using neural stem cells expressing carboxylesterase, a CPT-11 activating enzyme. Curr Stem Cell Res Ther 2010; 5: 273-6.
    • (2010) Curr Stem Cell Res Ther , vol.5 , pp. 273-276
    • Gutova, M.1    Najbauer, J.2    Chen, M.Y.3
  • 48
    • 79951841819 scopus 로고    scopus 로고
    • Concise review: Dissecting a discrepancy in the literature: Do mesenchymal stem cells support or suppress tumor growth?
    • Klopp AH, Gupta A, Spaeth E, et al. Concise review: Dissecting a discrepancy in the literature: do mesenchymal stem cells support or suppress tumor growth? Stem Cells 2011; 29: 11-9.
    • (2011) Stem Cells , vol.29 , pp. 11-19
    • Klopp, A.H.1    Gupta, A.2    Spaeth, E.3
  • 49
    • 62449339080 scopus 로고    scopus 로고
    • Rat umbilical cord stem cells completely abolish rat mammary carcinomas with no evidence of metastasis or recurrence 100 days post-tumor cell inoculation
    • Ganta C, Chiyo D, Ayuzawa R, et al. Rat umbilical cord stem cells completely abolish rat mammary carcinomas with no evidence of metastasis or recurrence 100 days post-tumor cell inoculation. Cancer Res 2009; 69: 1815-20.
    • (2009) Cancer Res , vol.69 , pp. 1815-1820
    • Ganta, C.1    Chiyo, D.2    Ayuzawa, R.3
  • 50
    • 77958548514 scopus 로고    scopus 로고
    • Therapy with unengineered naive rat umbilical cord matrix stem cells markedly inhibits growth of murine lung adenocarcinoma
    • Maurya DK, Doi C, Kawabata A, et al. Therapy with unengineered naive rat umbilical cord matrix stem cells markedly inhibits growth of murine lung adenocarcinoma. BMC Cancer 2010; 10: 590.
    • (2010) BMC Cancer , vol.10 , pp. 590
    • Maurya, D.K.1    Doi, C.2    Kawabata, A.3
  • 51
    • 77951217116 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice
    • Doi C, Egashira N, Kawabata A, et al. Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice. BMC Cancer 2010; 67.
    • (2010) BMC Cancer , pp. 67
    • Doi, C.1    Egashira, N.2    Kawabata, A.3
  • 52
    • 33744470579 scopus 로고    scopus 로고
    • Targeting of melanoma brain metastases using engineered neural stem/progenitor cells
    • Aboody KS, Najbauer J, Schmidt NO, et al. Targeting of melanoma brain metastases using engineered neural stem/progenitor cells. Neuro Oncol 2006; 8: 119-26.
    • (2006) Neuro Oncol , vol.8 , pp. 119-126
    • Aboody, K.S.1    Najbauer, J.2    Schmidt, N.O.3
  • 53
    • 43049088843 scopus 로고    scopus 로고
    • Stem and progenitor cellmediated tumor selective gene therapy
    • Aboody KS, Najbauer J., Danks MK. Stem and progenitor cellmediated tumor selective gene therapy. Gene Ther 2008; 15: 739-52.
    • (2008) Gene Ther , vol.15 , pp. 739-752
    • Aboody, K.S.1    Najbauer, J.2    Danks, M.K.3
  • 54
    • 0032902337 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons
    • Simons M, Beinroth S, Gleichmann M, et al. Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons. J Neurochem 1999; 72: 292-301.
    • (1999) J Neurochem , vol.72 , pp. 292-301
    • Simons, M.1    Beinroth, S.2    Gleichmann, M.3
  • 56
    • 0031009429 scopus 로고    scopus 로고
    • Extrarenal aspects of angiotensin II function
    • Csikos T, Gallinat S.T. Extrarenal aspects of angiotensin II function. Eur J Endocrinol 1997; 136: 349-58.
    • (1997) Eur J Endocrinol , vol.136 , pp. 349-358
    • Csikos, T.1    Gallinat, S.T.2
  • 58
    • 38049181475 scopus 로고    scopus 로고
    • Immunogenicity of umbilical cord tissue derived cells
    • Cho PS, Messina DJ, Hirsh EL, et al. Immunogenicity of umbilical cord tissue derived cells. Blood 2008; 111: 430-8.
    • (2008) Blood , vol.111 , pp. 430-438
    • Cho, P.S.1    Messina, D.J.2    Hirsh, E.L.3
  • 59
    • 67650869280 scopus 로고    scopus 로고
    • Adult stromal cells derived from human adipose tissue provoke pancreatic cancer cell death both in vitro and in vivo
    • Cousin B, Ravet E, Poglio S, et al. Adult stromal cells derived from human adipose tissue provoke pancreatic cancer cell death both in vitro and in vivo. PLoS One 2009; 4: e6278.
    • (2009) PLoS One , vol.4
    • Cousin, B.1    Ravet, E.2    Poglio, S.3
  • 60
  • 61
    • 77955239592 scopus 로고    scopus 로고
    • Human bone marrow mesenchymal stem cells display anti-cancer activity in SCID mice bearing disseminated non-Hodgkin's lymphoma xenografts
    • Secchiero P, Zorzet S, Tripodo C, et al. Human bone marrow mesenchymal stem cells display anti-cancer activity in SCID mice bearing disseminated non-Hodgkin's lymphoma xenografts. PLoS One 2010; 5: e11140.
    • (2010) PLoS One , vol.5
    • Secchiero, P.1    Zorzet, S.2    Tripodo, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.