Novel sources of fetal stem cells: Where do they fit on the developmental continuum?

Regenerative Medicine

Volumn 4, Issue 3, 2009, Pages 423-433

  Pappa, Kalliopi I ^a,b   Anagnou, Nicholas P ^a,b  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b Academy of Athens Biomedical Research Foundation   (Greece)

Author keywords

Amnion; Amniotic fluid; Differentiation; Fetal stem cells; Mesenchymal stem cells; Placenta; Plasticity; Pluripotency; Umbilical cord; Wharton's jelly

Indexed keywords

AMNION; AMNION FLUID; CELL DIFFERENTIATION; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; DEVELOPMENTAL STAGE; MESENCHYMAL STEM CELL; NONHUMAN; PLACENTA; PLASTICITY; PLURIPOTENT STEM CELL; PREGNANCY; PRIORITY JOURNAL; PROTEOMICS; REAL TIME POLYMERASE CHAIN REACTION; REVIEW; STEM CELL; TISSUE REGENERATION; TRANSCRIPTOMICS; TROPHOBLAST; UMBILICAL CORD; ADULT STEM CELL; BONE MARROW CELL; CELL LINEAGE; CYTOLOGY; EMBRYONIC STEM CELL; FETAL STEM CELL; HUMAN; METABOLISM; REGENERATIVE MEDICINE;

BIOLOGICAL MARKER;

ADULT STEM CELLS; BIOLOGICAL MARKERS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL LINEAGE; EMBRYONIC STEM CELLS; FETAL STEM CELLS; HUMANS; REGENERATIVE MEDICINE; UMBILICAL CORD;

EID: 68049144834     PISSN: 17460751     EISSN: None     Source Type: Journal    
DOI: 10.2217/rme.09.12     Document Type: Review

References (94)

1. Klimanskaya I, Rosenthal N, Lanza R: Derive and conquer: sourcing and differentiating stem cells for therapeutic applications. Nat. Rev. Drug Discov. 7, 131-142 (2008).
2. Hemberger M, Yang W, Natale D et al.: Stem cells from fetal membranes. A Workshop Report. Placenta 22, S17-S19 (2008).
3. Guillot PV, Gotherstrom C, Chan J, Kurata H, Fisk NM: Human first trimester fetal MSC express pluripotency markers and grow faster and have longer telomeres than adult MSC. Stem Cells 25, 646-654 (2007).
4. DeCoppi P, Bartsch G Jr, Siddiqui MM et al.: Isolation of amniotic stem cells with potential for therapy. Nat. Biotech. 25, 100-106 (2007).
5. Roubelakis MG, Pappa KI, Bitsika V et al.: Molecular and proteomic characterization of human mesenchymal stem cells derived from amniotic fluid: comparison to bone marrow mesenchymal stem cells. Stem Cells Dev. 16, 931-952 (2007).
6. Kim J, Lee Y, Kim H et al.: Human amniotic fluid-derived stem cells have characteristics of multipotent stem cells. Cell Prolif. 40, 75-90 (2007).
7. Tsai MS, Lee JL, Chang YJ, Hwang SM: Isolation of human multipotent mesenchymal stem cells from second-trimester amniotic fluid using a novel two-stage culture protocol. Hum. Reprod. 19, 1450-1456 (2004).
8. Tsai MS, Hwang SM, Tsai YL, Cheng FC, Lee JL, Chang YJ: Clonal amniotic fluid-derived cells express characteristics of both mesenchymal and neural stem cells. Biol. Reprod. 74, 545-551 (2006).
9. Bossolasco P, Montemurro T, Cova L et al.: Molecular and phenotypic characterization of human amniotic fluid cells and their differentiation potential. Cell Res. 16, 329-336 (2006).
10. Prusa AR, Marton E, Rosner M, Bernaschek G, Hengstschläger M: Oct-4 expressing cells in human amniotic fluid: a new source for stem cell research? Hum. Reprod. 18, 1489-1493 (2003).
11. Prusa AR, Marton E, Rosner M et al.: Neurogenic cells in human amniotic fluid. Am. J. Obstet. Gynecol. 191, 309-314 (2004).
12. Perin L, Sedrakyan S, Da Sacco S, De Filippo R: Characterization of human amniotic fluid stem cells and their pluripotential capacity. Methods Cell Biol. 86, 85-99 (2008).
13. Zhao P, Ise H, Hongo M, Ota M, Konishi I, Nikaido T: Human amniotic mesenchymal cells have some characteristics of cardiomyocytes. Transplantation 79, 528-535 (2005).
14. Kolambkar YM, Peister A, Soker S, Atala A, Guldberg RE: Chondrogenic differentiation of amniotic fluid-derived stem cells. J. Mol. Histol. 38, 405-413 (2007).
15. Kunisaki SM, Armant M, Kao GS, Stevenson K, Kim H, Fauza DO: Tissue engineering from human mesenchymal amniocytes: a prelude to clinical trials. J. Pediatr. Surg. 42, 974-980 (2007).
16. Sessarego N, Parodi A, Podestà M et al.: Multipotent mesenchymal stromal cells from amniotic fluid: solid perspectives for clinical application. Haematologica 93, 339-346 (2008).
17. Tsai MS, Hwang SM, Chen KD et al.: Functional network analysis on the transcriptomes of mesenchymal stem cells derived from amniotic fluid, amniotic membrane, cord blood, and bone marrow. Stem Cells 25, 2511-2523 (2007).
18. Sartore S, Lenzi M, Angelini A et al.: Amniotic mesenchymal cells autotransplanted in a porcine model of cardiac ischemia do not differentiate to cardiogenic phenotypes. Eur. J. Cardiothorac. Surg. 28, 677-684 (2005).
19. Chiavegato A, Bollini S, Pozzobon M et al.: Human amniotic fluid-derived stem cells are rejected after transplantation in the myocardium of normal, ischemic, immuno-suppressed or immuno-deficient rat. J. Mol. Cell. Cardiol. 42, 746-759 (2007).
20. Pan HC, Yang DY, Chiu YT et al.: Enhanced regeneration in injured sciatic nerve by human amniotic mesenchymal stem cell. J. Clin. Neurosci. 13, 570-575 (2006).
21. Schmidt D, Achermann J, Odermatt B et al.: Prenatally fabricated autologous human living heart valves based on amniotic fluid-derived progenitor cells as single cell source. Circulation 116, S64-S70 (2007).
22. De Coppi P, Callegari A, Chiavegato A et al.: Amniotic fluid and bone marrow derived mesenchymal stem cells can be converted to smooth muscle cells in the cryo-injured rat bladder and prevent compensatory hypertrophy of surviving smooth muscle cells. J. Urol. 117, 369-376 (2007).
23. Broxmeyer HE, Srour E, Orschell C et al.: Cord blood stem cell and progenitor cells. Methods Enzymol. 419, 439-473 (2006).
24. Broxmeyer HE: Biology of cord blood cells and future prospects for enhanced clinical benefit. Cytotherapy 7, 209-218 (2005).
25. Mazurier F, Doedens M, Gan OI: Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells. Nat. Med. 9, 953-963 (2003).
26. McNiece IK, Almeida-Parada G, Shpall EJ: Ex vivo expanded cord blood cells provide rapid engraftment in fetal sheep but lack long-term engrafting potential. Exp. Hematol. 30, 612-616 (2002).
27. Stier S, Cheng T, Dombkowski D: Notch-1 activation increases hemopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome. Blood 99, 2369-2378 (2002).
28. Reya T, Duncan AW, Ailles L: A role for Wnt signaling in self-renewal of haematopoietic stem cells. Nature 423, 409-414 (2003).
29. Tao W, Broxmeyer HE: Towards a molecular understanding of hematopoietic stem cell and progenitor cells. In: Cord Blood: Biology, Immunology, Banking, and Clinical Transplantation. Broxmeyer HE (Ed.). American Association of Blood Banking, Bethesda, MD, USA 87-123 (2004).
30. + hematopoietic stem cells and for chondrogenic differentiation. Haematologica 89, 837-844 (2004).
31. Javazon EH, Beggs KJ, Flake AW: Mesenchymal stem cells: paradoxes of passaging. Exp. Hematol. 32, 414-425 (2004).
32. McGuckin CP, Forraz N, Allouard Q, Pettengel R: Umbilical cord blood stem cells can expand hematopoietic and neuroglial progenitors in vitro. Exp. Cell Res. 295, 350-359 (2004).
33. Sanchez-Ramos J: Stem cells from human umbilical cord blood. Sem. Reprod. Med. 24, 358-369 (2006).
34. Koponen JK, Kekarainen T, Heinonen SE et al.: Umbilical cord blood-derived progenitor cells enhance muscle regeneration in mouse hindlimb ischemia model. Mol. Ther. 15, 2172-2177 (2007).
35. Tondreau T, Meuleman N, Delforge A et al.: Mesenchymal stem cells derived from CD133-positive cells in mobilized peripheral blood and cord blood: proliferation, Oct4 expression, and plasticity. Stem Cells 23, 1105-1112 (2005).
36. Greco SJ, Lin K, Rameshwar P: Functional similarities among genes regulated by Oct4 in human mesenchymal and embryonic stem cells. Stem Cells 25, 3143-3154 (2007).
37. McGuckin CP, Forraz N, Baradez MO et al.: Production of stem cells with embryonic characteristics from human umbilical cord blood. Cell Prolif. 38, 245-255 (2005).
38. Zhao Y, Wang H, Mazzone T: Identification of stem cells from human umbilical cord blood with embryonic and hematopoietic characteristics. Exp. Cell Res. 312, 2454-2464 (2006).
39. Markov V, Kusumi K, Tadesse M et al.: Identification of cord blood-derived mesenchymal stem/stromal cell populations with distinct growth kinetics, differentiation potentials, and gene expression profiles. Stem Cells Dev. 16, 53-73 (2007).
40. Sun B, Roh KH, Lee SR, Lee YS, Kang KS: Induction of human umbilical cord blood-derived stem cells with embryonic stem cell phenotypes into insulin producing islet-like structure. Biochem. Biophys. Res. Commun. 354, 919-923 (2007).
41. Lee OK, Kuo TK, Chen WM, Lee KD, Hsieh SL, Chen TH: Isolation of multipotent mesenchymal stem cells from umbilical cord blood. Blood 103, 1669-1675 (2004).
42. Reinisch A, Bartmann C, Rohde E et al.: Humanized system to propagate cord blood-derived multipotent mesenchymal stromal cells for clinical application. Regen. Med. 2, 371-382 (2008).
43. Chang YJ, Shih DT, Tseng CP, Hsieh TB, Lee DC, Hwang SM: Disparate mesenchyme-lineage tendencies in mesenchymal stem cells from human bone marrow and umbilical cord blood. Stem Cells 24, 679-685 (2006).
44. Chang YJ, Tseng CP, Hsu LF, Hsieh TB, Hwang SM: Characterization of two populations of mesenchymal progenitor cells in umbilical cord blood. Cell Biol. Int. 30, 495-499 (2006).
45. Weiss ML, Medicetty S, Bledsoe AR et al.: Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease. Stem Cells 24, 781-792 (2006).
46. Sarugaser R, Lickorish D, Baksh D, Hosseini MM, Davies JE: Human umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitors. Stem Cells 23, 220-229 (2005).
47. Karahuseyinoglou S, Cinar O, Kilic E et al.: Biology of stem cells in human umbilical cord stroma: in situ and in vitro surveys. Stem Cells 25, 319-331 (2007).
48. Mitchell KE, Weiss ML, Mitchell BM et al.: Matrix cells from Wharton's jelly form neurons and glia. Stem Cells 21, 50-60 (2003).
49. Wang HS, Hung SC, Peng ST et al.: Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord. Stem Cells 22, 1330-1337 (2004).
50. Takechi K, Kuwabara Y, Mizuno M: Ultrastructural and immunohistochemical studies of Wharton's jelly umbilical cord cells. Placenta 14, 235-245 (1993).
51. Fu YS, Cheng YC, Lin MY et al.: Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism. Stem Cells 24, 115-124 (2006).
52. Carlin R, Davis D, Weiss M, Schultz B, Troyer D: Expression of early transcription factors Oct4, Sox2 and Nanog by porcine umbilical cord (PUC) matrix cells. Reprod. Biol. Endocrinol. 4, 8 (2006).
53. + cells from Wharton's jelly show in vitro and in vivo myogenic differentiation potential. Int. J. Mol. Med. 18, 1089-1096 (2006).
54. Ilancheran S, Michalska A, Peh G, Wallace EM, Pera M, Manuelpillai U: Stem cells derived from human fetal membranes display multilineage differentiation potential. Biol. Reprod. 77, 577-588 (2007).
55. Miki T, Mitamura K, Ross MA, Stolz DB, Strom SC: Identification of stem cell marker-positive cells by immunofluoresence in term human amnion. J. Reprod. Immunol. 75, 91-96 (2007).
56. Miki T, Strom SC: Amnion-derived pluripotent/multipotent stem cells. Stem Cell Rev. 2, 133-142 (2006).
57. Marcus AJ, Coyne TM, Rauch J, Woodbury D, Black IB: Isolation, characterization and differentiation of stem cells derived from the rat amniotic membrane. Differentiation 76, 130-144 (2008).
58. Alviano F, Fossati V, Marchionni C et al.: Term amniotic membrane is a high throughput source for multipotent mesenchymal stem cells with the ability to differentiate into endothelial cells in vitro. BMC Dev. Biol. 7, 11 (2007).
59. Tamagawa T, Oi S, Ishiwata I, Ishikawa H, Nakamura Y: Differentiation of mesenchymal cells derived from human amniotic membranes into hepatocyte-like cells in vitro. Hum. Cell 20, 77-84 (2007).
60. Wolbank S, Peterbauer A, Fahrner M et al.: Dose-dependent immunomodulatory effect of human stem cells from amniotic membrane: a comparison with human mesenchymal stem cells from adipose tissue. Tissue Eng. 13, 1173-1183 (2007).
61. Keating A: How do mesenchymal stromal cells suppress T cells? Cell Stem Cell 2, 106-108 (2008).
62. Parolini O, Alviano F, Bagnara GP et al.: Isolation and characterization of cells from human term placenta: outcome of the First International Workshop on Placenta-Derived Stem Cells. Stem Cells 26, 300-311 (2008).
63. Wen F, Tynan JA, Cecena G et al.: Ets2 is required for trophoblast stem cell self-renewal. Dev. Biol. 312, 284-299 (2007).
64. Battula VL, Treml S, Abele H, Bühring HJ: Prospective isolation and characterization of mesenchymal stem cells from human placenta using a frizzled-9-specific monoclonal antibody. Differentiation 76, 326-336 (2008).
65. Strakova Z, Livak M, Krezalek M, Ihnatovych I: Multipotent properties of myofibroblasts cells derived from human placenta. Cell Tissue Res. 332, 479-488 (2008).
66. Kim SJ, Song CH, Sung HJ et al.: Human placenta-derived feeders support prolonged undifferentiated propagation of a human embryonic stem cell line, SNUhES3: comparison with human bone marrow-derived feeders. Stem Cells Dev. 16, 421-428 (2007).
67. Miao Z, Jin J, Chen L et al.: Isolation of mesenchymal stem cells from human placenta: comparison with human bone marrow mesenchymal stem cells. Cell Biol. Int. 30, 681-687 (2006).
68. Li C, Zhang W, Jiang X, Mao N: Human placenta-derived mesenchymal stem cells inhibit proliferation and function of allogeneic immune cells. Cell Tissue Res. 330, 437-446 (2007).
69. Jones BJ, Brooke G, Atkinson K, McTaggart SJ: Immunosuppression by placental indoleamine 2,3-dioxygenase: a role for mesenchymal stem cells. Placenta 28, 1174-1181 (2007).
70. Li D, Wang GY, Dong BH, Zhang YC, Wang YX, Sun BC: Biological characteristics of human placental mesenchymal stem cells and their proliferative response to various cytokines. Cells Tissues Organs 186, 169-179 (2007).
71. Battula VL, Bareiss PM, Treml S et al.: Human placenta and bone-marrow derived MSC cultured in serum-free, b-FGF-containing medium express cell surface frizzled-9 and SSEA-4 and give rise to multilineage differentiation. Differentiation 75, 279-291 (2007).
72. Fukuchi Y, Nakajima H, Sugiyama D, Hirose I, Kitamura T, Tsuji K: Human placenta-derived cells have mesenchymal stem/progenitor cell potential. Stem Cells 22, 649-658 (2004).
73. In't Anker PS, Scherjon SA, Kleijburg-van der Keur C et al.: Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. Stem Cells 22, 1338-1345 (2004).
74. Portmann-Lanz CB, Schoeberlein A, Huber A et al.: Placental mesenchymal stem cells as potential autologous graft for pre- and perinatal neuroregeneration. Am. J. Obstet. Gynecol. 194, 664-673 (2006).
75. Yen BL, Chien CC, Chen YC et al.: Placenta-derived multipotent cells differentiate into neuronal and glial cells in vitro. Tissue Eng. Part A 14, 9-17 (2008).
76. Chang CM, Kao CL, Chang YL et al.: Placenta-derived multipotent stem cells induced to differentiate into insulin-positive cells. Biochem. Biophys. Res. Commun. 357, 414-420 (2007).
77. Chien CC, Yenn Bl, Lee FK et al.: In vitro differentiation of human placenta-derived multipotent cells into hepatocyte-like cells. Stem Cells 24, 1759-1768 (2006).
78. Schmidt D, Mol A, Breymann C et al.: Living autologous heart valves engineered from human prenatally harvested progenitors. Circulation 114, S125-S131 (2006).
79. Zhang HJ, Siu MKY, Wong ESY, Wong KY, Li ASM, Chan KYK: Oct-4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease. Placenta 29, 549-554 (2008).
80. Wu CC, Chao YC, Chen CN et al.: Synergism of biochemical and mechanical stimuli in the differentiation of human placenta-derived multipotent cells into endothelial cells. J. Biomech. 41, 813-821 (2008).
81. Lang I, Schweizer A, Hidden U et al.: Human fetal placenta endothelial cells have a mature arterial and a juvenile venous phenotype with adipogenic and osteogenic differentiation potential. Differentiation 76, 1031-1043 (2008).
82. Brooke G, Tong H, Levesque JP, Atkinson K: Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placenta. Stem Cells Dev. 17, 929-940. (2008).
83. Prather WR, Toren A, Meiron M: Placental-derived and expanded mesenchymal stromal cells (PLX-I) to enhance the engraftment of hematopoietic stem cells derived from umbilical cord blood. Expert Opin. Biol. Ther. 8, 1241-1250 (2008).
84. Kim JS, Romero R, Tarca A et al.: Gene expression profiling demonstrates a novel role for fetal fibrocytes and the umbilical vessels in human fetoplacental development. J. Cell. Mol. Med. 12, 1317-1330 (2008).
85. Chen CP, Lee MY, Huang JP et al.: Trafficking of multipotent mesenchymal stromal cells from maternal circulation through the placenta involves vascular endothelial growth factor-1 and integrins. Stem Cells 26, 550-561 (2008).
86. Rhodes KE, Gekas C, Wang Y et al.: The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation. Cell Stem Cell 2, 252-263 (2008).
87. Soupene E, Serikov V, Kuypers FA: Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells. Lipid Res. 49, 1103-1112 (2008).
88. Mao JL, Kurman RJ, Huang CC, Lin MC, Shih IEM: Immunohistochemistry of choriocarcinoma: an aid in differential diagnosis and in elucidating pathogenesis. Am. J. Surg. Pathol. 31, 1726-1732 (2007).
89. Daley GQ, Hyun I, Lindvall O: Mapping the road to the clinical translation of stem cells. Cell Stem Cell 2, 139-140 (2008).
90. Jaenisch R, Young R: The molecular circuitry of pluripotency and nuclear reprogramming. Cell 132, 567-582 (2008).
91. Rossant J: Stem cells and early lineage development. Cell 132, 527-531 (2008).
92. Emanuel P: AFS cells - where do they fit on the continuum? The Hematologist: ASH News and Reports 4, 1 (2007).
93. Gilbert SF: The early development of vertebrates. In: Developmental Biology (8th Edition). Sinauer Associates, Inc., MA, USA 353 (2006).
94. Gilbert SF, Tyler AL, Zackin EJ: Bioethics and the New Embryology: Springboards for the Debate. Sinauer Associates, Inc., MA, USA 20 (2005).