BB14, a Nerve Growth Factor (NGF)-like peptide shown to be effective in reducing reactive astrogliosis and restoring synaptic homeostasis in a rat model of peripheral nerve injury

Biotechnology Advances

Volumn 30, Issue 1, 2012, Pages 223-232

  Cirillo, Giovanni ^a   Colangelo, Anna Maria ^b   Bianco, Maria Rosaria ^a   Cavaliere, Carlo ^a   Zaccaro, Laura ^d   Sarmientos, Paolo ^c   Alberghina, Lilia ^b   Papa, Michele ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

^c Primm Srl   (Italy)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Nerve injury; Neuro glial network; NGF like peptide; Reactive astrocytosis; Synaptic homeostasis

Indexed keywords

ASTROGLIOSIS; BENEFICIAL EFFECTS; GABAERGIC; GLUTAMATE TRANSPORTERS; GLUTATHIONES; HYPERALGESIA; IMMUNOHISTOCHEMICAL ANALYSIS; MOLECULAR CHANGES; NERVE GROWTH FACTOR; NERVE INJURIES; NEURODEGENERATIVE DISORDERS; NEUROPATHIC PAIN; NEUROPLASTIC CHANGES; NEUROPROTECTION; PATHOLOGICAL CONDITIONS; PEPTIDOMIMETICS; PERIPHERAL NERVES; RAT MODEL; REACTIVE ASTROCYTOSIS; SCIATIC NERVES; SPINAL CORDS; SYNAPTIC HOMEOSTASIS; THERAPEUTIC AGENTS;

DOSIMETRY; NEURODEGENERATIVE DISEASES; PHYSIOLOGY;

PEPTIDES;

ANALGESIC AGENT; GLUTAMIC ACID; GLUTATHIONE; GLYCINE; NERVE GROWTH FACTOR;

BIOMARKER; CORRELATION; HOMEOSTASIS; INHIBITOR; INJURY; PEPTIDE; RODENT;

ANIMAL; ARTICLE; CHEMISTRY; DISEASE MODEL; DRUG EFFECT; GLIOSIS; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; PERIPHERAL NERVE INJURY; RAT; SPINAL CORD; SPINAL CORD INJURY; SPRAGUE DAWLEY RAT; SYNAPSE;

ANALGESICS; ANIMALS; DISEASE MODELS, ANIMAL; GLIOSIS; GLUTAMIC ACID; GLUTATHIONE; GLYCINE; IMMUNOHISTOCHEMISTRY; MALE; NERVE GROWTH FACTOR; PERIPHERAL NERVE INJURIES; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SPINAL CORD INJURIES; SYNAPSES;

RATTUS;

EID: 84855746317     PISSN: 07349750     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biotechadv.2011.05.008     Document Type: Article

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