-
2
-
-
36549036104
-
The genetic basis of complex traits: rare variants or common gene, common disease?
-
Totowa, New Jersey, USA: Humana Press
-
Iyengar SK, Elston RC. The genetic basis of complex traits: rare variants or common gene, common disease? Linkage Disequilibrium and Association Mapping: Analysis and Applications, Vol. 376. Totowa, New Jersey, USA: Humana Press, 2007, 71-84.
-
(2007)
Linkage Disequilibrium and Association Mapping: Analysis and Applications
, vol.376
, pp. 71-84
-
-
Iyengar, S.K.1
Elston, R.C.2
-
3
-
-
84889376220
-
Population Association
-
3rd edn. Chichester Sussex: Wiley Interscience
-
Clayton D. Population Association. Handbook of Statistical Genetics, Vol. 2, 3rd edn. Chichester, Sussex: Wiley Interscience, 2007, 1216-37.
-
(2007)
Handbook of Statistical Genetics
, vol.2
, pp. 1216-1237
-
-
Clayton, D.1
-
4
-
-
84889296916
-
Whole genome association
-
3rd edn. Chichester, Sussex: Wiley Interscience
-
Morris AP, Cardon LR. Whole genome association. Handbook of Statistical Genetics, Vol. 2, 3rd edn. Chichester, Sussex: Wiley Interscience, 2007, 1238-63.
-
(2007)
Handbook of Statistical Genetics
, vol.2
, pp. 1238-1263
-
-
Morris, A.P.1
Cardon, L.R.2
-
5
-
-
42349112088
-
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
-
McCarthy MI, Abecasis GR, Cardon LR, et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet 2008;9(5): 356-69.
-
(2008)
Nat Rev Genet
, vol.9
, Issue.5
, pp. 356-369
-
-
McCarthy, M.I.1
Abecasis, G.R.2
Cardon, L.R.3
-
6
-
-
33748804424
-
A tutorial on statistical methods for population association studies
-
Balding DJ. A tutorial on statistical methods for population association studies. Nat Genet 2006;7:781-90.
-
(2006)
Nat Genet
, vol.7
, pp. 781-790
-
-
Balding, D.J.1
-
9
-
-
84855702365
-
Graphical models in genetics
-
3rd edn. Chichester, Sussex: Wiley Interscience
-
Lauritzen SL. Graphical models in genetics. Handbook of Statistical Genetics, Vol. 2, 3rd edn. Chichester, Sussex: Wiley Interscience, 2007, 808-42.
-
(2007)
Handbook of Statistical Genetics
, vol.2
, pp. 808-842
-
-
Lauritzen, S.L.1
-
10
-
-
0004047518
-
-
Oxford Statistical Science Series. New York, USA: Oxford University Press
-
Lauritzen SL. Graphical Models. Oxford Statistical Science Series. New York, USA: Oxford University Press, 1996.
-
(1996)
Graphical Models
-
-
Lauritzen, S.L.1
-
12
-
-
0002629270
-
Maximum likelihood from incomplete data via the EM algorithm
-
Dempster A, Laird N, Rubin D. Maximum likelihood from incomplete data via the EM algorithm. J R Stat Soc 1977;B 39:1-38.
-
(1977)
J R Stat Soc
, vol.B 39
, pp. 1-38
-
-
Dempster, F.A.1
Laird, F.N.2
Rubin, F.D.3
-
13
-
-
0002157592
-
Learning Bayesian networks: search methods and experimental results
-
Intelligence and Statistics. Springer
-
Chickering D, Geiger D, Heckerman D. Learning Bayesian networks: search methods and experimental results. In: Proceedings of Fifth Conference on Artificial Intelligence and Statistics. Springer, 1995;112-128.
-
(1995)
Proceedings of Fifth Conference on Artificia
, pp. 112-128
-
-
Chickering, D.1
Geiger, D.2
Heckerman, D.3
-
14
-
-
51849110999
-
A tutorial on learning with Bayesian networks
-
Holmes DE, Jain LC, (eds), chapter 3, Berlin, Heidelberg: Springer
-
Heckerman D. A tutorial on learning with Bayesian networks. In Holmes DE, Jain LC, (eds). Innovations in Bayesian Networks, Vol. 156 of Studies in Computational Intelligence, chapter 3, Berlin, Heidelberg: Springer, 2008, 33-82.
-
(2008)
Innovations in Bayesian Networks, Vol. 156 of Studies in Computational Intelligence
, pp. 33-82
-
-
Heckerman, D.1
-
15
-
-
0000120766
-
Estimating the dimension of a model
-
Schwartz G. Estimating the dimension of a model. Ann Stat 1978;6(2):461-4.
-
(1978)
Ann Stat
, vol.6
, Issue.2
, pp. 461-464
-
-
Schwartz, G.1
-
18
-
-
33746035971
-
The max-min hill-climbing Bayesian network structure learning algorithm
-
Tsamardinos I, Brown and Constantin A. The max-min hill-climbing Bayesian network structure learning algorithm. Mach Learn 2006;65(1):31-78.
-
(2006)
Mach Learn
, vol.65
, Issue.1
, pp. 31-78
-
-
Tsamardinos, I.1
Brown, L.2
Constantin, A.3
-
19
-
-
44449153601
-
Discovery of latent structures: experience with the coil challenge 2000 data set
-
Zhang NL, Wang Y, Chen T. Discovery of latent structures: experience with the coil challenge 2000 data set. J Syst Sci Complex 2007;21(2):172-83.
-
(2007)
J Syst Sci Complex
, vol.21
, Issue.2
, pp. 172-183
-
-
Zhang, N.L.1
Wang, Y.2
Chen, T.3
-
20
-
-
60349088003
-
Estimation of graphical models whose conditional independence graphs are interval graphs and its application to modelling linkage disequilibrium
-
Thomas A. Estimation of graphical models whose conditional independence graphs are interval graphs and its application to modelling linkage disequilibrium. Comput Stat Data Anal 2009a;53(5):1818-28.
-
(2009)
Comput Stat Data Anal
, vol.53
, Issue.5
, pp. 1818-1828
-
-
Thomas, A.1
-
21
-
-
65549105499
-
A method and program for estimating graphical models for linkage disequilibrium that scale linearly with the number of loci, and their application to gene drop simulation
-
Thomas A. A method and program for estimating graphical models for linkage disequilibrium that scale linearly with the number of loci, and their application to gene drop simulation. Bioinformatics 2009b;25(10):1287-92.
-
(2009)
Bioinformatics
, vol.25
, Issue.10
, pp. 1287-1292
-
-
Thomas, A.1
-
22
-
-
68949163877
-
Bayesian network structure learning by recursive autonomy identification
-
Yehezkel R, Lerner B. Bayesian network structure learning by recursive autonomy identification. J Mach Learn Res 2009;10:1527-70.
-
(2009)
J Mach Learn Res
, vol.10
, pp. 1527-1570
-
-
Yehezkel, R.1
Lerner, B.2
-
23
-
-
79951470778
-
Accuracy and computational efficiency of a graphical modeling approach to linkage disequilibrium estimation
-
Abel HJ, Thomas A. Accuracy and computational efficiency of a graphical modeling approach to linkage disequilibrium estimation. Stat Appl GenetMol Biol 2011;10(1):5.
-
(2011)
Stat Appl GenetMol Biol
, vol.10
, Issue.1
, pp. 5
-
-
Abel, H.J.1
Thomas, A.2
-
24
-
-
0034977045
-
Linkage disequilibrium in Humans: models and data
-
Pritchard JK, Przeworski M. Linkage disequilibrium in Humans: models and data. AmJ Human Genet 2001;69(1): 1-14.
-
(2001)
AmJ Human Genet
, vol.69
, Issue.1
, pp. 1-14
-
-
Pritchard, J.K.1
Przeworski, M.2
-
25
-
-
79959524146
-
A haplotype map of the human genome
-
The International HapMap Consortium
-
The International HapMap Consortium. A haplotype map of the human genome. Nature 2005;437:1299-320.
-
(2005)
Nature
, vol.437
, pp. 1299-1320
-
-
-
26
-
-
52949149045
-
Linkage analysis
-
3rd edn. Chichester Sussex: Wiley Interscience
-
Thompson EA. Linkage analysis. Handbook of Statistical Genetics, Vol. 2, 3rd edn. Chichester, Sussex: Wiley Interscience, 2007, 1141-67.
-
(2007)
Handbook of Statistical Genetics
, vol.2
, pp. 1141-1167
-
-
Thompson, E.A.1
-
27
-
-
33747892180
-
BNTagger: improved tagging SNP selection using Bayesian networks
-
Lee PH, Shatkay H. BNTagger: improved tagging SNP selection using Bayesian networks. Bioinformatics 2006; 22(14):211-19.
-
(2006)
Bioinformatics
, vol.22
, Issue.14
, pp. 211-219
-
-
Lee, P.H.1
Shatkay, H.2
-
28
-
-
77956545115
-
Modeling associations between genetic markers using Bayesian networks
-
Villanueva E, Maciel CDD. Modeling associations between genetic markers using Bayesian networks. Bioinformatics 2010;26(18):i632-37.
-
(2010)
Bioinformatics
, vol.26
, Issue.18
-
-
Villanueva, E.1
Maciel, C.D.D.2
-
29
-
-
2442713792
-
Graphical modeling of the joint distribution of alleles at associated loci
-
Thomas A, Camp NJ. Graphical modeling of the joint distribution of alleles at associated loci. AmJ Human Genet 2004;74:1088-101.
-
(2004)
AmJ Human Genet
, vol.74
, pp. 1088-1101
-
-
Thomas, A.1
Camp, N.J.2
-
32
-
-
33644974019
-
A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase
-
Scheet P, Stephens M. A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase. Am J Human Genet 2006;78(4):629-44.
-
(2006)
Am J Human Genet
, vol.78
, Issue.4
, pp. 629-644
-
-
Scheet, P.1
Stephens, M.2
-
34
-
-
78651241266
-
A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-wide association studies
-
Mourad R, Sinoquet C, Leray P. A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-wide association studies. BMC Bioinformatics 2011; 12:16.
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 16
-
-
Mourad, R.1
Sinoquet, C.2
Leray, P.3
-
35
-
-
72449152648
-
Enumerating the junction trees of a decomposable graph
-
Thomas A, Green PJ. Enumerating the junction trees of a decomposable graph. J Comput Graph Stat 2009b;18(4): 930-40.
-
(2009)
J Comput Graph Stat
, vol.18
, Issue.4
, pp. 930-940
-
-
Thomas, A.1
Green, P.J.2
-
36
-
-
58549118244
-
Enumerating the decomposable neighbors of a decomposable graph under a simple perturbation scheme
-
Thomas A, Green P. Enumerating the decomposable neighbors of a decomposable graph under a simple perturbation scheme. Comput Stat Data Anal 2009a;53(4): 1232-8.
-
(2009)
Comput Stat Data Anal
, vol.53
, Issue.4
, pp. 1232-1238
-
-
Thomas, A.1
Green, P.2
-
37
-
-
0001006209
-
Local computations with probabilities on graphical structures and their application to expert systems
-
Lauritzen SL, Spiegelhalter DJ. Local computations with probabilities on graphical structures and their application to expert systems. J R Stat Soc Ser B Methodol 1988;50(2): 157-224.
-
(1988)
J R Stat Soc Ser B Methodol
, vol.50
, Issue.2
, pp. 157-224
-
-
Lauritzen, S.L.1
Spiegelhalter, D.J.2
-
38
-
-
6344233909
-
Finding haplotype tagging SNPs by use of principal components analysis
-
Lin Z, Altman RB. Finding haplotype tagging SNPs by use of principal components analysis. AmJ Human Genet 2004; 75(5):850-61.
-
(2004)
AmJ Human Genet
, vol.75
, Issue.5
, pp. 850-861
-
-
Lin, Z.1
Altman, R.B.2
-
39
-
-
84860539286
-
Tag SNP selection in genotype data for maximizing SNP prediction accuracy
-
Halperin E, Kimmel G, Shamir R. Tag SNP selection in genotype data for maximizing SNP prediction accuracy. Bioinformatics 2005;21(Suppl 1):1195-203.
-
(2005)
Bioinformatics
, vol.21
, Issue.SUPPL. 1
, pp. 1195-1203
-
-
Halperin, E.1
Kimmel, G.2
Shamir, R.3
-
40
-
-
35348817330
-
Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering
-
Browning SR, Browning BL. Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering. AmJ Human Genet 2007;81(5):1084-97.
-
(2007)
AmJ Human Genet
, vol.81
, Issue.5
, pp. 1084-1097
-
-
Browning, S.R.1
Browning, B.L.2
-
41
-
-
13844302126
-
High density linkage disequilibrium mapping using models of haplotype block variation
-
Greenspan G, Geiger D. High density linkage disequilibrium mapping using models of haplotype block variation. Bioinformatics 2004;20:137-44.
-
(2004)
Bioinformatics
, vol.20
, pp. 137-144
-
-
Greenspan, G.1
Geiger, D.2
-
42
-
-
33646191869
-
Modeling haplotype block variation using Markov chains
-
Greenspan GD, Geiger D. Modeling haplotype block variation using Markov chains. Genetics 2005;172:2583-99.
-
(2005)
Genetics
, vol.172
, pp. 2583-2599
-
-
Greenspan, G.D.1
Geiger, D.2
-
43
-
-
13444304032
-
Mining genetic epidemiology data with Bayesian networks application to APOE gene variation and plasma lipid levels
-
Rodin A, Mosley TH, Clark AG, et al. Mining genetic epidemiology data with Bayesian networks application to APOE gene variation and plasma lipid levels. J Comput Biol 2005;12(1):1-11.
-
(2005)
J Comput Biol
, vol.12
, Issue.1
, pp. 1-11
-
-
Rodin, A.1
Mosley, T.H.2
Clark, A.G.3
-
44
-
-
21344454198
-
Characterizing allelic associations from unphased diploid data by graphical modeling
-
Thomas A. Characterizing allelic associations from unphased diploid data by graphical modeling. Genet Epidemiol 2005; 29(1):23-35.
-
(2005)
Genet Epidemiol
, vol.29
, Issue.1
, pp. 23-35
-
-
Thomas, A.1
-
45
-
-
16844366938
-
Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia
-
Sebastiani P, Ramoni MF, Nolan V, etal. Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia. Nat Genet 2005;37(4):435-40.
-
(2005)
Nat Genet
, vol.37
, Issue.4
, pp. 435-440
-
-
Sebastiani, P.1
Ramoni, M.F.2
Nolan, V.3
-
46
-
-
63049094001
-
Phenotype forecasting with SNPs data through gene-based Bayesian networks
-
Malovini A, Nuzzo A, Ferrazzi F, et al. Phenotype forecasting with SNPs data through gene-based Bayesian networks. BMC Bioinformatics 2009;10(Suppl 2):S7.
-
(2009)
BMC Bioinformatics
, vol.10
, Issue.SUPPL. 2
-
-
Malovini, A.1
Nuzzo, A.2
Ferrazzi, F.3
-
47
-
-
33646869900
-
Multilocus association mapping using variable-length Markov chains
-
Browning SR. Multilocus association mapping using variable-length Markov chains. AmJ Human Genet 2006;78(6): 903-13.
-
(2006)
AmJ Human Genet
, vol.78
, Issue.6
, pp. 903-913
-
-
Browning, S.R.1
-
48
-
-
33745276855
-
Bayesian graphical models for genome-wide association studies
-
Verzilli CJ, Stallard N, Whittaker JC. Bayesian graphical models for genome-wide association studies. AmJ Human Genet 2006;79:100-12.
-
(2006)
AmJ Human Genet
, vol.79
, pp. 100-112
-
-
Verzilli, C.J.1
Stallard, N.2
Whittaker, J.C.3
-
49
-
-
70349303959
-
Bayesian statistical methods for genetic association studies
-
Stephens M, Balding DJ. Bayesian statistical methods for genetic association studies. Nat Rev Genet 2009;10(10): 681-90.
-
(2009)
Nat Rev Genet
, vol.10
, Issue.10
, pp. 681-690
-
-
Stephens, M.1
Balding, D.J.2
-
50
-
-
77952257916
-
A Markov blanket-based method for detecting causal SNPs in GWAS
-
Han B, Park M, Chen XW. A Markov blanket-based method for detecting causal SNPs in GWAS. BMC Bioinformatics 2010;11(Suppl 3):S5.
-
(2010)
BMC Bioinformatics
, vol.11
, Issue.SUPPL. 3
-
-
Han, B.1
Park, M.2
Chen, X.W.3
-
51
-
-
0034973569
-
Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer
-
Ritchie MD, Hahn LW, Roodi N, et al. Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. AmJ Human Genet 2001;69(1):138-47.
-
(2001)
AmJ Human Genet
, vol.69
, Issue.1
, pp. 138-147
-
-
Ritchie, M.D.1
Hahn, L.W.2
Roodi, N.3
-
52
-
-
34548352849
-
Bayesian inference of epistatic interactions in case-control studies
-
Zhang Y, Liu JS. Bayesian inference of epistatic interactions in case-control studies. Nat Genet 2007;39(9):1167-73.
-
(2007)
Nat Genet
, vol.39
, Issue.9
, pp. 1167-1173
-
-
Zhang, Y.1
Liu, J.S.2
-
53
-
-
34547638844
-
Genetic association mapping via evolution-based clustering of haplotypes
-
Tachmazidou I, Verzilli CJ, Iorio MD. Genetic association mapping via evolution-based clustering of haplotypes. PLoS Genet 2007;3(7):e111.
-
(2007)
PLoS Genet
, vol.3
, Issue.7
-
-
Tachmazidou, I.1
Verzilli, C.J.2
Iorio, M.D.3
-
54
-
-
45849134070
-
Sparse inverse covariance estimation with the graphical lasso
-
Friedman J, Hastie T, Tibshirani R. Sparse inverse covariance estimation with the graphical lasso. Biostatistics 2008; 9(3):432-41.
-
(2008)
Biostatistics
, vol.9
, Issue.3
, pp. 432-441
-
-
Friedman, J.1
Hastie, T.2
Tibshirani, R.3
-
56
-
-
84855682054
-
Inferring causal associations between genes and disease via the mapping of expression quantitative loci
-
3rd edn. Wiley Interscience
-
Sieberts SK, Schadt EE. Inferring causal associations between genes and disease via the mapping of expression quantitative loci. Handbook of Statistical Genetics, Vol. 2, 3rd edn. Wiley Interscience, 2007, 296-326.
-
(2007)
Handbook of Statistical Genetics
, vol.2
, pp. 296-326
-
-
Sieberts, S.K.1
Schadt, E.E.2
-
57
-
-
57649124192
-
Reverse engineering the genotypephenotype map with natural genetic variation
-
Rockman MV. Reverse engineering the genotypephenotype map with natural genetic variation. Nature 2008;456(7223):738-44.
-
(2008)
Nature
, vol.456
, Issue.7223
, pp. 738-744
-
-
Rockman, M.V.1
-
58
-
-
67651015931
-
A graphical model approach for inferring large-scale networks integrating gene expression and genetic polymorphism
-
Chu JH, Weiss ST, Carey VJ, et al. A graphical model approach for inferring large-scale networks integrating gene expression and genetic polymorphism. BMC Syst Biol 2009;3(1):55.
-
(2009)
BMC Syst Biol
, vol.3
, Issue.1
, pp. 55
-
-
Chu, J.H.1
Weiss, S.T.2
Carey, V.J.3
-
60
-
-
22844446947
-
An integrative genomics approach to infer causal associations between gene expression and disease
-
Schadt EE, Lamb J, Yang X, et al. An integrative genomics approach to infer causal associations between gene expression and disease. Nat Genet 2005;37:710-17.
-
(2005)
Nat Genet
, vol.37
, pp. 710-717
-
-
Schadt, E.E.1
Lamb, J.2
Yang, X.3
-
61
-
-
49449089907
-
Genomics and genome-wide association studies: an integrative approach to expression QTL mapping
-
Degnan JH, Lasky-Su J, Raby BA, et al. Genomics and genome-wide association studies: an integrative approach to expression QTL mapping. Genomics 2008;92(3):129-33.
-
(2008)
Genomics
, vol.92
, Issue.3
, pp. 129-133
-
-
Degnan, J.H.1
Lasky-Su, J.2
Raby, B.A.3
-
62
-
-
55449096399
-
Genetical genomics: spotlight on QTL hotspots
-
Breitling R, Li Y, Tesson BM, et al. Genetical genomics: spotlight on QTL hotspots. PLoS Genet 2008;4(10): e1000232.
-
(2008)
PLoS Genet
, vol.4
, Issue.10
-
-
Breitling, R.1
Li, Y.2
Tesson, B.M.3
-
63
-
-
66349118643
-
A systems-based framework for understanding complex metabolic and cardiovascular disorders
-
Wu S, Lusis AJ, Drake TA. A systems-based framework for understanding complex metabolic and cardiovascular disorders. J Lipid Res 2009;50(Suppl):S358-63.
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
-
-
Wu, S.1
Lusis, A.J.2
Drake, T.A.3
-
64
-
-
46949101742
-
Exploiting the proteome to improve the genome-wide genetic analysis of epistasis in common human diseases
-
Pattin K, Moore J. Exploiting the proteome to improve the genome-wide genetic analysis of epistasis in common human diseases. Human Genet 2008;124(1):19-29.
-
(2008)
Human Genet
, vol.124
, Issue.1
, pp. 19-29
-
-
Pattin, K.1
Moore, J.2
|