Inhibition of PPARγ in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis

Blood

Volumn 119, Issue 1, 2012, Pages 115-126

  Wu, Lingyan ^a   Yan, Cong ^a,b   Czader, Magdalena ^a   Foreman, Oded ^c   Blum, Janice S ^a   Kapur, Reuben ^a   Du, Hong ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; DOXYCYCLINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 7 RECEPTOR ALPHA; LYMPHOKINE; LYSOSOMAL ACID LIPASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STAT3 PROTEIN; SYNAPTOPHYSIN; TRIACYLGLYCEROL LIPASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CARCINOGENESIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE OVEREXPRESSION; GRANULOCYTE; HISTOPATHOLOGY; HOMEOSTASIS; IMMUNE DEFICIENCY; INFLAMMATION; LIVER CARCINOMA; LIVER SARCOMA; LUNG CARCINOMA; LUNG SARCOMA; LYMPHOMA; MONOCYTE; MOUSE; NONHUMAN; PLASMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; SARCOMA; SPLEEN TUMOR; UPREGULATION;

EID: 84855591618     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-06-363093     Document Type: Article

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