-
1
-
-
12944271053
-
Cancer statistics, 2005
-
Jemal A, Murray T, Ward E, et al. Cancer statistics, 2005. CA Cancer J Clin. 2005;55:10-30.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 10-30
-
-
Jemal, A.1
Murray, T.2
Ward, E.3
-
3
-
-
33645739589
-
Tumours of the lung
-
Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC, editors. Lyon: International Agency for Research on Cancer (IARC)
-
Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC. Tumours of the lung. In: Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC, editors. Pathology and Genetics: Tumours of the Lung, Pleura, Thymus and Heart. Lyon: International Agency for Research on Cancer (IARC), 2004:9-124.
-
(2004)
Pathology and Genetics: Tumours of the Lung, Pleura, Thymus and Heart
, pp. 9-124
-
-
Travis, W.D.1
Brambilla, E.2
Muller-Hermelink, H.K.3
Harris, C.C.4
-
5
-
-
0022930702
-
Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism
-
Sen R, Baltimore D. Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism. Cell. 1986;47:921-928.
-
(1986)
Cell
, vol.47
, pp. 921-928
-
-
Sen, R.1
Baltimore, D.2
-
6
-
-
4544342570
-
Nuclear factor-kappaB: The enemy within
-
Aggarwal BB. Nuclear factor-kappaB: the enemy within. Cancer Cell. 2004;6:203-208.
-
(2004)
Cancer Cell
, vol.6
, pp. 203-208
-
-
Aggarwal, B.B.1
-
7
-
-
4143134494
-
Nuclear factor-kappaB: A friend or a foe in cancer?
-
Shishodia S, Aggarwal BB. Nuclear factor-kappaB: a friend or a foe in cancer? Biochem Pharmacol. 2004;68:1071-1080.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 1071-1080
-
-
Shishodia, S.1
Aggarwal, B.B.2
-
8
-
-
0033565217
-
Expression of a dominant-negative mutant inhibitor-kappaBalpha of nuclear factor-kappaB in human head and neck squamous cell carcinoma inhibits survival, proinflammatory cytokine expression, and tumor growth in vivo
-
Duffey DC, Chen Z, Dong G, et al. Expression of a dominant-negative mutant inhibitor-kappaBalpha of nuclear factor-kappaB in human head and neck squamous cell carcinoma inhibits survival, proinflammatory cytokine expression, and tumor growth in vivo. Cancer Res. 1999;59:3468-3474.
-
(1999)
Cancer Res
, vol.59
, pp. 3468-3474
-
-
Duffey, D.C.1
Chen, Z.2
Dong, G.3
-
9
-
-
0742269868
-
Nuclear factor-kappa B as a predictor of treatment response in breast cancer
-
Garg AK, Hortobagyi GN, Aggarwal BB, Sahin AA, Buchholz TA. Nuclear factor-kappa B as a predictor of treatment response in breast cancer. Curr Opin Oncol. 2003;15:405-11.
-
(2003)
Curr Opin Oncol
, vol.15
, pp. 405-411
-
-
Garg, A.K.1
Hortobagyi, G.N.2
Aggarwal, B.B.3
Sahin, A.A.4
Buchholz, T.A.5
-
10
-
-
16644397046
-
Nuclear factor-kappaB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate
-
Sweeney C, Li L, Shanmugam R, et al. Nuclear factor-kappaB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate. Clin Cancer Res. 2004;10:5501-5507.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5501-5507
-
-
Sweeney, C.1
Li, L.2
Shanmugam, R.3
-
11
-
-
17644400134
-
Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer
-
Lee BL, Lee HS, Jung J, et al. Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer. Clin Cancer Res. 2005;11:2518-2525.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2518-2525
-
-
Lee, B.L.1
Lee, H.S.2
Jung, J.3
-
12
-
-
7644223910
-
Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis
-
Li L, Aggarwal BB, Shishodia S, Abbruzzese J, Kurzrock R. Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis. Cancer. 2004;101:2351-2362.
-
(2004)
Cancer
, vol.101
, pp. 2351-2362
-
-
Li, L.1
Aggarwal, B.B.2
Shishodia, S.3
Abbruzzese, J.4
Kurzrock, R.5
-
13
-
-
4644324186
-
NF-kappaB functions as a tumour promoter in inflammation-associated cancer
-
Pikarsky E, Porat RM, Stein I, et al. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature.
-
Nature
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
-
14
-
-
4544224979
-
Inhibition of NF-kappaB in cancer cells converts inflammation-induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression
-
Luo JL, Maeda S, Hsu LC, Yagita H, Karin M. Inhibition of NF-kappaB in cancer cells converts inflammation-induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression. Cancer Cell. 2004;6:297-305.
-
(2004)
Cancer Cell
, vol.6
, pp. 297-305
-
-
Luo, J.L.1
Maeda, S.2
Hsu, L.C.3
Yagita, H.4
Karin, M.5
-
15
-
-
4043088499
-
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten FR, Eckmann L, Greten TF, et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell. 2004;118:285-296.
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
-
16
-
-
25844459154
-
NF-kappaB: Linking inflammation and immunity to cancer development and progression
-
Karin M, Greten FR. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol. 2005;5:749-759.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
17
-
-
0042565930
-
The potential contributions of chronic inflammation to lung carcinogenesis
-
Ballaz S, Mulshine JL. The potential contributions of chronic inflammation to lung carcinogenesis. Clin Lung Cancer. 2003;5:46-62.
-
(2003)
Clin Lung Cancer
, vol.5
, pp. 46-62
-
-
Ballaz, S.1
Mulshine, J.L.2
-
18
-
-
0037304945
-
Acquired somatic mutations in the molecular pathogenesis of COPD
-
Anderson GP, Bozinovski S. Acquired somatic mutations in the molecular pathogenesis of COPD. Trends Pharmacol Sci. 2003;24:71-76.
-
(2003)
Trends Pharmacol Sci
, vol.24
, pp. 71-76
-
-
Anderson, G.P.1
Bozinovski, S.2
-
19
-
-
21344464734
-
Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells
-
Tsurutani J, Castillo SS, Brognard J, et al. Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells. Carcinogenesis. 2005;26:1182-1195.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1182-1195
-
-
Tsurutani, J.1
Castillo, S.S.2
Brognard, J.3
-
20
-
-
3242771185
-
Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: Correlation with suppression of COX-2 synthesis
-
Sbishodia S, Koul D, Aggarwal BB. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis. J Immunol. 2004;173:2011-2022.
-
(2004)
J Immunol
, vol.173
, pp. 2011-2022
-
-
Sbishodia, S.1
Koul, D.2
Aggarwal, B.B.3
-
21
-
-
0030912190
-
Revisions in the International System for Staging Lung Cancer
-
Mountain CF. Revisions in the International System for Staging Lung Cancer. Chest. 1997;111:1710-1717.
-
(1997)
Chest
, vol.111
, pp. 1710-1717
-
-
Mountain, C.F.1
-
22
-
-
3142776304
-
Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates activation of cigarette smoke-induced nuclear factor (NF)-kappaB by suppressing activation of IkappaBalpha kinase in human non-small cell lung carcinoma: Correlation with suppression of cyclin D1, COX-2, and matrix metalloproteinase-9
-
Shishodia S, Aggarwal BB. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates activation of cigarette smoke-induced nuclear factor (NF)-kappaB by suppressing activation of IkappaBalpha kinase in human non-small cell lung carcinoma: correlation with suppression of cyclin D1, COX-2, and matrix metalloproteinase-9. Cancer Res.
-
Cancer Res
-
-
Shishodia, S.1
Aggarwal, B.B.2
-
23
-
-
33644853585
-
Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma
-
Izzo JG, Malhotra U, Wu TT, et al. Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma. J Clin Oncol. 2006;24:748-54.
-
(2006)
J Clin Oncol
, vol.24
, pp. 748-754
-
-
Izzo, J.G.1
Malhotra, U.2
Wu, T.T.3
-
24
-
-
0037351342
-
NF-kappa B nuclear localization and its prognostic significance in prostate cancer
-
Lessard L, Mes-Masson AM, Lamarre L, Wall L, Lattouf JB, Saad F. NF-kappa B nuclear localization and its prognostic significance in prostate cancer. BJU Int. 2003;91:417-20.
-
(2003)
BJU Int
, vol.91
, pp. 417-420
-
-
Lessard, L.1
Mes-Masson, A.M.2
Lamarre, L.3
Wall, L.4
Lattouf, J.B.5
Saad, F.6
-
25
-
-
0842327809
-
Expression of NF-kappaB in prostate cancer lymph node metastases
-
Ismail HA, Lessard L, Mes-Masson AM, Saad F. Expression of NF-kappaB in prostate cancer lymph node metastases. Prostate. 2004;58(3):308-I3.
-
(2004)
Prostate
, vol.58
, Issue.3
-
-
Ismail, H.A.1
Lessard, L.2
Mes-Masson, A.M.3
Saad, F.4
-
28
-
-
0034879150
-
Transcriptional regulation of the BCL-X gene by NF-kappaB is an element of hypoxic responses in the rat brain
-
Glasgow JN, Qiu J, Rassin D, Grafe M, Wood T, Perez-Pol JR. Transcriptional regulation of the BCL-X gene by NF-kappaB is an element of hypoxic responses in the rat brain. Neurochem Res. 2001;26:647-659.
-
(2001)
Neurochem Res
, vol.26
, pp. 647-659
-
-
Glasgow, J.N.1
Qiu, J.2
Rassin, D.3
Grafe, M.4
Wood, T.5
Perez-Pol, J.R.6
-
29
-
-
0032954928
-
Transcriptional cross talk between NF-kappaB and p53
-
Webster GA, Perkins ND. Transcriptional cross talk between NF-kappaB and p53. Mol Cell Biol. 1999;19:3485-3495.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3485-3495
-
-
Webster, G.A.1
Perkins, N.D.2
-
30
-
-
0029858387
-
TNF-and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
-
Wang CY, Mayo MW, Baldwin AS Jr. TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science. 1996;274:784-787.
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin Jr., A.S.3
-
31
-
-
0036964816
-
Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization
-
Bharti AC, Aggarwal BB. Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization. Ann N Y Acad Sci. 2002;973:392-395.
-
(2002)
Ann N Y Acad Sci
, vol.973
, pp. 392-395
-
-
Bharti, A.C.1
Aggarwal, B.B.2
-
32
-
-
0036301285
-
Cyclooxygenase-2 induction by paclitaxel, docetaxel, and taxane analogues in human monocytes and murine macrophages: Structure-activity relationships and their implications
-
Cassidy PB, Moos PJ, Kelly RC, Fitzpatrick FA. Cyclooxygenase-2 induction by paclitaxel, docetaxel, and taxane analogues in human monocytes and murine macrophages: structure-activity relationships and their implications. Clin Cancer Res. 2002;8:846-855.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 846-855
-
-
Cassidy, P.B.1
Moos, P.J.2
Kelly, R.C.3
Fitzpatrick, F.A.4
-
33
-
-
0141844522
-
Regulation of cyclooxgenase-2 mRNA stability by taxanes: Evidence for involvement of p38, MAPKAPK-2, and FluR
-
Subbaramaiah K, Marmo TP, Dixon DA, Dannenberg AJ. Regulation of cyclooxgenase-2 mRNA stability by taxanes: evidence for involvement of p38, MAPKAPK-2, and FluR. J Biol Chem. 2003;278:37637-37647.
-
(2003)
J Biol Chem
, vol.278
, pp. 37637-37647
-
-
Subbaramaiah, K.1
Marmo, T.P.2
Dixon, D.A.3
Dannenberg, A.J.4
-
34
-
-
25144442153
-
Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: A phase 11 trial of celecoxib and docetaxel
-
Csiki I, Morrow JD, Sandler A, et al. Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: a phase 11 trial of celecoxib and docetaxel. Clin Cancer Res. 2005;11:6634-6640.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6634-6640
-
-
Csiki, I.1
Morrow, J.D.2
Sandler, A.3
-
35
-
-
20344380457
-
Chemotherapy induces the expression of cyclooxygenase-2 in non-small cell lung cancer
-
Altorki NK, Port JL, Zhang F, et al. Chemotherapy induces the expression of cyclooxygenase-2 in non-small cell lung cancer. Clin Cancer Res. 2005;11:4191-4197.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4191-4197
-
-
Altorki, N.K.1
Port, J.L.2
Zhang, F.3
-
36
-
-
1542328234
-
The IKK/NF-kappaB activation pathway - A target for prevention and treatment of cancer
-
Greten FR, Karin M. The IKK/NF-kappaB activation pathway - a target for prevention and treatment of cancer. Cancer Lett. 2004;206:193-199.
-
(2004)
Cancer Lett
, vol.206
, pp. 193-199
-
-
Greten, F.R.1
Karin, M.2
-
37
-
-
0038281345
-
Downstream effectors of oncogenic ras in multiple myeloma cells
-
Hu L, Shi Y, Hsu JH, Gera J, Van Ness B, Lichtenstein A. Downstream effectors of oncogenic ras in multiple myeloma cells. Blood. 2003;101:3126-3135.
-
(2003)
Blood
, vol.101
, pp. 3126-3135
-
-
Hu, L.1
Shi, Y.2
Hsu, J.H.3
Gera, J.4
Van Ness, B.5
Lichtenstein, A.6
-
38
-
-
0034682527
-
Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells
-
Biswas DK, Cruz AP, Gansberger E, Pardee AB. Epidermal growth factor-induced nuclear factor kappa B activation: a major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells. Proc Natl Acad Sci U S A. 2000;97:8542-8547.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 8542-8547
-
-
Biswas, D.K.1
Cruz, A.P.2
Gansberger, E.3
Pardee, A.B.4
-
39
-
-
20044364940
-
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
-
Shigematsu H, Lin L, Takahashi T, et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst. 2005;97:339-346.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 339-346
-
-
Shigematsu, H.1
Lin, L.2
Takahashi, T.3
-
40
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420:860-867.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
41
-
-
0035065024
-
Pulmonary preinvasive neoplasia
-
Kerr KM. Pulmonary preinvasive neoplasia. J Clin Pathol. 2001;54:257-271.
-
(2001)
J Clin Pathol
, vol.54
, pp. 257-271
-
-
Kerr, K.M.1
-
42
-
-
0037152658
-
Smoking molecular damage in bronchial epithelium
-
Wistuba II, Mao L, Gazdar AF. Smoking molecular damage in bronchial epithelium. Oncogene. 2002;21:7298-7306.
-
(2002)
Oncogene
, vol.21
, pp. 7298-7306
-
-
Wistuba, I.I.1
Mao, L.2
Gazdar, A.F.3
-
43
-
-
23044488525
-
Overexpression of phosphorylated nuclear factor-kappa B in consular squamous cell carcinoma and high-grade dysplasia is associated with poor prognosis
-
Zhang PL, Pellitteri PK, Law A, et al. Overexpression of phosphorylated nuclear factor-kappa B in consular squamous cell carcinoma and high-grade dysplasia is associated with poor prognosis. Mod Pathol. 2005;18:924-932.
-
(2005)
Mod Pathol
, vol.18
, pp. 924-932
-
-
Zhang, P.L.1
Pellitteri, P.K.2
Law, A.3
-
44
-
-
1642334954
-
NF-kappaB activation in esophageal adenocarcinoma: Relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy
-
Abdel-Latif MM, O'Riordan J, Windle HJ, et al. NF-kappaB activation in esophageal adenocarcinoma: relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy. Ann Surg. 2004;239:491-500.
-
(2004)
Ann Surg
, vol.239
, pp. 491-500
-
-
Abdel-Latif, M.M.1
O'Riordan, J.2
Windle, H.J.3
-
45
-
-
0037890342
-
Early glandular neoplasia of the lung
-
Westra WH. Early glandular neoplasia of the lung. Respir Med. 2000;1:163-169.
-
(2000)
Respir Med
, vol.1
, pp. 163-169
-
-
Westra, W.H.1
-
46
-
-
29244445792
-
Increased staining for phospho-Akt, p65/RELA and clAP-2 in pre-neoplastic human bronchial biopsies
-
Tichelaar JW, Zhang Y, leRiche JC, Biddinger PW, Lam S, Anderson MW. Increased staining for phospho-Akt, p65/RELA and clAP-2 in pre-neoplastic human bronchial biopsies. BMC Cancer. 2005;5:155.
-
(2005)
BMC Cancer
, vol.5
, pp. 155
-
-
Tichelaar, J.W.1
Zhang, Y.2
Leriche, J.C.3
Biddinger, P.W.4
Lam, S.5
Anderson, M.W.6
-
47
-
-
31544467105
-
Celecoxib decreases Ki-67 proliferative index in active smokers
-
Mao JT, Fishbein MC, Adams B, et al. Celecoxib decreases Ki-67 proliferative index in active smokers. Clin Cancer Res. 2006;12:314-320.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 314-320
-
-
Mao, J.T.1
Fishbein, M.C.2
Adams, B.3
-
48
-
-
33646028804
-
Molecular targets of dietary agents for prevention and therapy of cancer
-
Aggarwal BB, Shishodia S. Molecular targets of dietary agents for prevention and therapy of cancer. Biochem Pharmacol. 2006;71:1397-1421.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 1397-1421
-
-
Aggarwal, B.B.1
Shishodia, S.2
|