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Volumn 107, Issue 11, 2006, Pages 2637-2646

Nuclear factor-κB (NF-κB) is frequently expressed in lung cancer and preneoplastic lesions

Author keywords

EGFR mutation; Inflammation; K RAS mutation; Lung cancer; Lung preneoplasia; Nf B; Squamous dysplasia

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; K RAS PROTEIN; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR RELA;

EID: 33751570051     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.22315     Document Type: Article
Times cited : (178)

References (49)
  • 5
    • 0022930702 scopus 로고
    • Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism
    • Sen R, Baltimore D. Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism. Cell. 1986;47:921-928.
    • (1986) Cell , vol.47 , pp. 921-928
    • Sen, R.1    Baltimore, D.2
  • 6
    • 4544342570 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: The enemy within
    • Aggarwal BB. Nuclear factor-kappaB: the enemy within. Cancer Cell. 2004;6:203-208.
    • (2004) Cancer Cell , vol.6 , pp. 203-208
    • Aggarwal, B.B.1
  • 7
    • 4143134494 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: A friend or a foe in cancer?
    • Shishodia S, Aggarwal BB. Nuclear factor-kappaB: a friend or a foe in cancer? Biochem Pharmacol. 2004;68:1071-1080.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1071-1080
    • Shishodia, S.1    Aggarwal, B.B.2
  • 8
    • 0033565217 scopus 로고    scopus 로고
    • Expression of a dominant-negative mutant inhibitor-kappaBalpha of nuclear factor-kappaB in human head and neck squamous cell carcinoma inhibits survival, proinflammatory cytokine expression, and tumor growth in vivo
    • Duffey DC, Chen Z, Dong G, et al. Expression of a dominant-negative mutant inhibitor-kappaBalpha of nuclear factor-kappaB in human head and neck squamous cell carcinoma inhibits survival, proinflammatory cytokine expression, and tumor growth in vivo. Cancer Res. 1999;59:3468-3474.
    • (1999) Cancer Res , vol.59 , pp. 3468-3474
    • Duffey, D.C.1    Chen, Z.2    Dong, G.3
  • 10
    • 16644397046 scopus 로고    scopus 로고
    • Nuclear factor-kappaB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate
    • Sweeney C, Li L, Shanmugam R, et al. Nuclear factor-kappaB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate. Clin Cancer Res. 2004;10:5501-5507.
    • (2004) Clin Cancer Res , vol.10 , pp. 5501-5507
    • Sweeney, C.1    Li, L.2    Shanmugam, R.3
  • 11
    • 17644400134 scopus 로고    scopus 로고
    • Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer
    • Lee BL, Lee HS, Jung J, et al. Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer. Clin Cancer Res. 2005;11:2518-2525.
    • (2005) Clin Cancer Res , vol.11 , pp. 2518-2525
    • Lee, B.L.1    Lee, H.S.2    Jung, J.3
  • 12
    • 7644223910 scopus 로고    scopus 로고
    • Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis
    • Li L, Aggarwal BB, Shishodia S, Abbruzzese J, Kurzrock R. Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis. Cancer. 2004;101:2351-2362.
    • (2004) Cancer , vol.101 , pp. 2351-2362
    • Li, L.1    Aggarwal, B.B.2    Shishodia, S.3    Abbruzzese, J.4    Kurzrock, R.5
  • 13
    • 4644324186 scopus 로고    scopus 로고
    • NF-kappaB functions as a tumour promoter in inflammation-associated cancer
    • Pikarsky E, Porat RM, Stein I, et al. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature.
    • Nature
    • Pikarsky, E.1    Porat, R.M.2    Stein, I.3
  • 14
    • 4544224979 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB in cancer cells converts inflammation-induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression
    • Luo JL, Maeda S, Hsu LC, Yagita H, Karin M. Inhibition of NF-kappaB in cancer cells converts inflammation-induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression. Cancer Cell. 2004;6:297-305.
    • (2004) Cancer Cell , vol.6 , pp. 297-305
    • Luo, J.L.1    Maeda, S.2    Hsu, L.C.3    Yagita, H.4    Karin, M.5
  • 15
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • Greten FR, Eckmann L, Greten TF, et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell. 2004;118:285-296.
    • (2004) Cell , vol.118 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3
  • 16
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: Linking inflammation and immunity to cancer development and progression
    • Karin M, Greten FR. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol. 2005;5:749-759.
    • (2005) Nat Rev Immunol , vol.5 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 17
    • 0042565930 scopus 로고    scopus 로고
    • The potential contributions of chronic inflammation to lung carcinogenesis
    • Ballaz S, Mulshine JL. The potential contributions of chronic inflammation to lung carcinogenesis. Clin Lung Cancer. 2003;5:46-62.
    • (2003) Clin Lung Cancer , vol.5 , pp. 46-62
    • Ballaz, S.1    Mulshine, J.L.2
  • 18
    • 0037304945 scopus 로고    scopus 로고
    • Acquired somatic mutations in the molecular pathogenesis of COPD
    • Anderson GP, Bozinovski S. Acquired somatic mutations in the molecular pathogenesis of COPD. Trends Pharmacol Sci. 2003;24:71-76.
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 71-76
    • Anderson, G.P.1    Bozinovski, S.2
  • 19
    • 21344464734 scopus 로고    scopus 로고
    • Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells
    • Tsurutani J, Castillo SS, Brognard J, et al. Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells. Carcinogenesis. 2005;26:1182-1195.
    • (2005) Carcinogenesis , vol.26 , pp. 1182-1195
    • Tsurutani, J.1    Castillo, S.S.2    Brognard, J.3
  • 20
    • 3242771185 scopus 로고    scopus 로고
    • Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: Correlation with suppression of COX-2 synthesis
    • Sbishodia S, Koul D, Aggarwal BB. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis. J Immunol. 2004;173:2011-2022.
    • (2004) J Immunol , vol.173 , pp. 2011-2022
    • Sbishodia, S.1    Koul, D.2    Aggarwal, B.B.3
  • 21
    • 0030912190 scopus 로고    scopus 로고
    • Revisions in the International System for Staging Lung Cancer
    • Mountain CF. Revisions in the International System for Staging Lung Cancer. Chest. 1997;111:1710-1717.
    • (1997) Chest , vol.111 , pp. 1710-1717
    • Mountain, C.F.1
  • 22
    • 3142776304 scopus 로고    scopus 로고
    • Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates activation of cigarette smoke-induced nuclear factor (NF)-kappaB by suppressing activation of IkappaBalpha kinase in human non-small cell lung carcinoma: Correlation with suppression of cyclin D1, COX-2, and matrix metalloproteinase-9
    • Shishodia S, Aggarwal BB. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates activation of cigarette smoke-induced nuclear factor (NF)-kappaB by suppressing activation of IkappaBalpha kinase in human non-small cell lung carcinoma: correlation with suppression of cyclin D1, COX-2, and matrix metalloproteinase-9. Cancer Res.
    • Cancer Res
    • Shishodia, S.1    Aggarwal, B.B.2
  • 23
    • 33644853585 scopus 로고    scopus 로고
    • Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma
    • Izzo JG, Malhotra U, Wu TT, et al. Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma. J Clin Oncol. 2006;24:748-54.
    • (2006) J Clin Oncol , vol.24 , pp. 748-754
    • Izzo, J.G.1    Malhotra, U.2    Wu, T.T.3
  • 24
    • 0037351342 scopus 로고    scopus 로고
    • NF-kappa B nuclear localization and its prognostic significance in prostate cancer
    • Lessard L, Mes-Masson AM, Lamarre L, Wall L, Lattouf JB, Saad F. NF-kappa B nuclear localization and its prognostic significance in prostate cancer. BJU Int. 2003;91:417-20.
    • (2003) BJU Int , vol.91 , pp. 417-420
    • Lessard, L.1    Mes-Masson, A.M.2    Lamarre, L.3    Wall, L.4    Lattouf, J.B.5    Saad, F.6
  • 25
    • 0842327809 scopus 로고    scopus 로고
    • Expression of NF-kappaB in prostate cancer lymph node metastases
    • Ismail HA, Lessard L, Mes-Masson AM, Saad F. Expression of NF-kappaB in prostate cancer lymph node metastases. Prostate. 2004;58(3):308-I3.
    • (2004) Prostate , vol.58 , Issue.3
    • Ismail, H.A.1    Lessard, L.2    Mes-Masson, A.M.3    Saad, F.4
  • 28
    • 0034879150 scopus 로고    scopus 로고
    • Transcriptional regulation of the BCL-X gene by NF-kappaB is an element of hypoxic responses in the rat brain
    • Glasgow JN, Qiu J, Rassin D, Grafe M, Wood T, Perez-Pol JR. Transcriptional regulation of the BCL-X gene by NF-kappaB is an element of hypoxic responses in the rat brain. Neurochem Res. 2001;26:647-659.
    • (2001) Neurochem Res , vol.26 , pp. 647-659
    • Glasgow, J.N.1    Qiu, J.2    Rassin, D.3    Grafe, M.4    Wood, T.5    Perez-Pol, J.R.6
  • 29
    • 0032954928 scopus 로고    scopus 로고
    • Transcriptional cross talk between NF-kappaB and p53
    • Webster GA, Perkins ND. Transcriptional cross talk between NF-kappaB and p53. Mol Cell Biol. 1999;19:3485-3495.
    • (1999) Mol Cell Biol , vol.19 , pp. 3485-3495
    • Webster, G.A.1    Perkins, N.D.2
  • 30
    • 0029858387 scopus 로고    scopus 로고
    • TNF-and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
    • Wang CY, Mayo MW, Baldwin AS Jr. TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science. 1996;274:784-787.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin Jr., A.S.3
  • 31
    • 0036964816 scopus 로고    scopus 로고
    • Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization
    • Bharti AC, Aggarwal BB. Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization. Ann N Y Acad Sci. 2002;973:392-395.
    • (2002) Ann N Y Acad Sci , vol.973 , pp. 392-395
    • Bharti, A.C.1    Aggarwal, B.B.2
  • 32
    • 0036301285 scopus 로고    scopus 로고
    • Cyclooxygenase-2 induction by paclitaxel, docetaxel, and taxane analogues in human monocytes and murine macrophages: Structure-activity relationships and their implications
    • Cassidy PB, Moos PJ, Kelly RC, Fitzpatrick FA. Cyclooxygenase-2 induction by paclitaxel, docetaxel, and taxane analogues in human monocytes and murine macrophages: structure-activity relationships and their implications. Clin Cancer Res. 2002;8:846-855.
    • (2002) Clin Cancer Res , vol.8 , pp. 846-855
    • Cassidy, P.B.1    Moos, P.J.2    Kelly, R.C.3    Fitzpatrick, F.A.4
  • 33
    • 0141844522 scopus 로고    scopus 로고
    • Regulation of cyclooxgenase-2 mRNA stability by taxanes: Evidence for involvement of p38, MAPKAPK-2, and FluR
    • Subbaramaiah K, Marmo TP, Dixon DA, Dannenberg AJ. Regulation of cyclooxgenase-2 mRNA stability by taxanes: evidence for involvement of p38, MAPKAPK-2, and FluR. J Biol Chem. 2003;278:37637-37647.
    • (2003) J Biol Chem , vol.278 , pp. 37637-37647
    • Subbaramaiah, K.1    Marmo, T.P.2    Dixon, D.A.3    Dannenberg, A.J.4
  • 34
    • 25144442153 scopus 로고    scopus 로고
    • Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: A phase 11 trial of celecoxib and docetaxel
    • Csiki I, Morrow JD, Sandler A, et al. Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: a phase 11 trial of celecoxib and docetaxel. Clin Cancer Res. 2005;11:6634-6640.
    • (2005) Clin Cancer Res , vol.11 , pp. 6634-6640
    • Csiki, I.1    Morrow, J.D.2    Sandler, A.3
  • 35
    • 20344380457 scopus 로고    scopus 로고
    • Chemotherapy induces the expression of cyclooxygenase-2 in non-small cell lung cancer
    • Altorki NK, Port JL, Zhang F, et al. Chemotherapy induces the expression of cyclooxygenase-2 in non-small cell lung cancer. Clin Cancer Res. 2005;11:4191-4197.
    • (2005) Clin Cancer Res , vol.11 , pp. 4191-4197
    • Altorki, N.K.1    Port, J.L.2    Zhang, F.3
  • 36
    • 1542328234 scopus 로고    scopus 로고
    • The IKK/NF-kappaB activation pathway - A target for prevention and treatment of cancer
    • Greten FR, Karin M. The IKK/NF-kappaB activation pathway - a target for prevention and treatment of cancer. Cancer Lett. 2004;206:193-199.
    • (2004) Cancer Lett , vol.206 , pp. 193-199
    • Greten, F.R.1    Karin, M.2
  • 37
    • 0038281345 scopus 로고    scopus 로고
    • Downstream effectors of oncogenic ras in multiple myeloma cells
    • Hu L, Shi Y, Hsu JH, Gera J, Van Ness B, Lichtenstein A. Downstream effectors of oncogenic ras in multiple myeloma cells. Blood. 2003;101:3126-3135.
    • (2003) Blood , vol.101 , pp. 3126-3135
    • Hu, L.1    Shi, Y.2    Hsu, J.H.3    Gera, J.4    Van Ness, B.5    Lichtenstein, A.6
  • 38
    • 0034682527 scopus 로고    scopus 로고
    • Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells
    • Biswas DK, Cruz AP, Gansberger E, Pardee AB. Epidermal growth factor-induced nuclear factor kappa B activation: a major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells. Proc Natl Acad Sci U S A. 2000;97:8542-8547.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 8542-8547
    • Biswas, D.K.1    Cruz, A.P.2    Gansberger, E.3    Pardee, A.B.4
  • 39
    • 20044364940 scopus 로고    scopus 로고
    • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
    • Shigematsu H, Lin L, Takahashi T, et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst. 2005;97:339-346.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 339-346
    • Shigematsu, H.1    Lin, L.2    Takahashi, T.3
  • 40
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420:860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 41
    • 0035065024 scopus 로고    scopus 로고
    • Pulmonary preinvasive neoplasia
    • Kerr KM. Pulmonary preinvasive neoplasia. J Clin Pathol. 2001;54:257-271.
    • (2001) J Clin Pathol , vol.54 , pp. 257-271
    • Kerr, K.M.1
  • 42
    • 0037152658 scopus 로고    scopus 로고
    • Smoking molecular damage in bronchial epithelium
    • Wistuba II, Mao L, Gazdar AF. Smoking molecular damage in bronchial epithelium. Oncogene. 2002;21:7298-7306.
    • (2002) Oncogene , vol.21 , pp. 7298-7306
    • Wistuba, I.I.1    Mao, L.2    Gazdar, A.F.3
  • 43
    • 23044488525 scopus 로고    scopus 로고
    • Overexpression of phosphorylated nuclear factor-kappa B in consular squamous cell carcinoma and high-grade dysplasia is associated with poor prognosis
    • Zhang PL, Pellitteri PK, Law A, et al. Overexpression of phosphorylated nuclear factor-kappa B in consular squamous cell carcinoma and high-grade dysplasia is associated with poor prognosis. Mod Pathol. 2005;18:924-932.
    • (2005) Mod Pathol , vol.18 , pp. 924-932
    • Zhang, P.L.1    Pellitteri, P.K.2    Law, A.3
  • 44
    • 1642334954 scopus 로고    scopus 로고
    • NF-kappaB activation in esophageal adenocarcinoma: Relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy
    • Abdel-Latif MM, O'Riordan J, Windle HJ, et al. NF-kappaB activation in esophageal adenocarcinoma: relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy. Ann Surg. 2004;239:491-500.
    • (2004) Ann Surg , vol.239 , pp. 491-500
    • Abdel-Latif, M.M.1    O'Riordan, J.2    Windle, H.J.3
  • 45
    • 0037890342 scopus 로고    scopus 로고
    • Early glandular neoplasia of the lung
    • Westra WH. Early glandular neoplasia of the lung. Respir Med. 2000;1:163-169.
    • (2000) Respir Med , vol.1 , pp. 163-169
    • Westra, W.H.1
  • 46
    • 29244445792 scopus 로고    scopus 로고
    • Increased staining for phospho-Akt, p65/RELA and clAP-2 in pre-neoplastic human bronchial biopsies
    • Tichelaar JW, Zhang Y, leRiche JC, Biddinger PW, Lam S, Anderson MW. Increased staining for phospho-Akt, p65/RELA and clAP-2 in pre-neoplastic human bronchial biopsies. BMC Cancer. 2005;5:155.
    • (2005) BMC Cancer , vol.5 , pp. 155
    • Tichelaar, J.W.1    Zhang, Y.2    Leriche, J.C.3    Biddinger, P.W.4    Lam, S.5    Anderson, M.W.6
  • 47
    • 31544467105 scopus 로고    scopus 로고
    • Celecoxib decreases Ki-67 proliferative index in active smokers
    • Mao JT, Fishbein MC, Adams B, et al. Celecoxib decreases Ki-67 proliferative index in active smokers. Clin Cancer Res. 2006;12:314-320.
    • (2006) Clin Cancer Res , vol.12 , pp. 314-320
    • Mao, J.T.1    Fishbein, M.C.2    Adams, B.3
  • 48
    • 33646028804 scopus 로고    scopus 로고
    • Molecular targets of dietary agents for prevention and therapy of cancer
    • Aggarwal BB, Shishodia S. Molecular targets of dietary agents for prevention and therapy of cancer. Biochem Pharmacol. 2006;71:1397-1421.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1397-1421
    • Aggarwal, B.B.1    Shishodia, S.2


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