Cobalt(II) β-ketoaminato complexes as novel inhibitors of neuroinflammation

European Journal of Pharmacology

Volumn 676, Issue 1-3, 2012, Pages 81-88

  Madeira, Jocelyn M ^a   Beloukhina, Natalia ^a   Boudreau, Kalun ^a   Boettcher, Tyson A ^a   Gurley, Lydia ^a   Walker, Douglas G ^b   McNeil, W Stephen ^a   Klegeris, Andis ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b SUN HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

Anti inflammatory drug; Glial cell; Metallocomplex; NADPH oxidase; Neuroprotection

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; COBALT COMPLEX; HEME OXYGENASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; OXOAMINO ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTROCYTOMA CELL; CELL SECRETION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; ENCEPHALITIS; ENZYME RELEASE; HUMAN; HUMAN CELL; MICROGLIA; NERVE CELL DIFFERENTIATION; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY BURST; UPREGULATION;

AMINES; ANTI-INFLAMMATORY AGENTS; ASTROCYTES; CELL RESPIRATION; COBALT; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEME OXYGENASE-1; HL-60 CELLS; HUMANS; INFLAMMATION; LIGANDS; MICROGLIA; MONOCYTES; NERVOUS SYSTEM DISEASES; ORGANOMETALLIC COMPOUNDS; P38 MITOGEN-ACTIVATED PROTEIN KINASES;

EID: 84855572413     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.11.038     Document Type: Article

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