Herpes simplex virus type 1 entry is inhibited by the cobalt chelate complex CTC-96

Journal of Virology

Volumn 75, Issue 9, 2001, Pages 4117-4128

  Schwartz, J A ^a   Lium, E K ^a   Silverstein, S J ^a  

^a New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; COBALT COMPLEX; CTC 96; DNA BINDING PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTACT INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DRUG INHIBITION; HERPES SIMPLEX VIRUS 1; MEMBRANE FUSION; NONHUMAN; PRIORITY JOURNAL; SYNCYTIUM; VERO CELL; VIRUS ADSORPTION; VIRUS PLAQUE;

ANIMALS; ANTIVIRAL AGENTS; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; CHO CELLS; COBALT; CRICETINAE; HERPES SIMPLEX VIRUS PROTEIN VMW65; HERPESVIRUS 1, HUMAN; HERPESVIRUS 3, HUMAN; HUMANS; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; RECEPTORS, VIRUS; RNA, MESSENGER; VERO CELLS; VIRAL ENVELOPE PROTEINS; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 0035051225     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.9.4117-4128.2001     Document Type: Article

References (108)

1. The polysulfonated compound suramin blocks adsorption and lateral diffusion of herpes simplex virus type-1 in Vero cells
2. New antiherpesvirus agents: Their targets and therapeutic potential
3. Efficacy of cobalt chelates in the rabbit eye model for epithelial herpetic keratitis
4. + (wild-type) phenotype
5. Antiviral drugs
6. Sequential isolation of proteoglycan synthesis mutants by using herpes simplex virus as a selective agent: Evidence for a proteoglycan-independent virus entry pathway
7. Isolation of a myoglobin molten globule by selective cobalt(III)-induced unfolding
8. Genetic studies with herpes simplex virus type 1. The isolation of temperature-sensitive mutants, their arrangement into complementation groups and recombination analysis leading to a linkage map
9. Role of glycoprotein B of herpes simplex virus type 1 in viral entry and cell fusion
10. Identification of herpes simplex virus DNA sequences which encode a trans-acting polypeptide responsible for stimulation of immediate early transcription
11. Oligomerization of herpes simplex virus glycoprotein B
12. The ectodomain of a novel member of the immunoglobulin subfamily related to the poliovirus receptor has the attribute of a bona fide receptor for herpes simplex virus types 1 and 2 in human cells
13. Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1
14. Characterization of a DNA polymerase mutant of herpes simplex virus from a severely immunocompromised patient receiving acyclovir
15. Infections with herpes simplex viruses
16. Infections with herpes simplex viruses
17. Molecular targets of antiviral therapy
18. Altered substrate specificity of herpes simplex virus thymidine kinase confers acyclovir-resistance
19. Analysis of the contributions of herpes simplex virus type 1 membrane proteins to the induction of cell-cell fusion
20. Epidemiology of sexually transmitted diseases: The global picture
21. Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate early regulatory protein ICP4
22. Efficacy of CTC topical therapy during HSV-1-induced epithelial and stromal keratitis in the rabbit
23. Fine structure mapping and functional analysis of temperature-sensitive mutants in the gene encoding the herpes simplex virus type 1 immediate early protein VP175
24. CTC 23 efficacy in vitro and on HSV-1-induced ocular epithelial and stromal disease in the rabbit
25. Dextran sulfate can act as an artificial receptor to mediate a type-specific herpes simplex virus infection via glycoprotein B
26. Selectivity of action of an antiherpetic agent 9-(2-hydroxyethoxymethyl)guanine
27. Clinical isolates of herpes simplex virus type 2 that induce a thymidine kinase with altered substrate specificity
28. Antiviral susceptibilities and analysis of UL97 and DNA polymerase sequences of clinical cytomegalovirus isolates from immunocompromised patients
29. Acyclovir-resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome
30. RNA synthesis in cells productively infected with herpes simplex virus. VIII. Control of transcription and of transcript abundancies of unique and common sequences of herpes simplex virus 1 and 2
31. Anti-glycoprotein D antibodies that permit adsorption but block infection by herpes simplex virus 1 prevent virion-cell fusion at the cell surface
32. Thymidine kinase from herpes simplex virus phosphorylates the antiviral compound, 9-(2-hydroxyethoxymethyl)guanine
33. Rabies virus-induced membrane fusion
34. Cellular expression of alphaherpesvirus gD interferes with entry of homologous and heterologous alphaherpesviruses by blocking access to a shared gD receptor
35. Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor
36. A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins
37. Herpes simplex virus mRNA species mapping in EcoRI F fragment
38. Glycoprotein C-independent binding of herpes simplex virus to cells requires cell surface heparan sulphate and glycoprotein B
39. Glycoprotein C of herpes simplex virus type 1 plays a principal role in the adsorption of virus to cells and in infectivity
40. Monoclonal antibodies define a domain on herpes simplex virus glycoprotein B involved in virus penetration
41. Neutralizing monoclonal antibodies specific for herpes simplex virus glycoprotein D inhibit virus penetration
42. Transcriptional and genetic analyses of the herpes simplex virus type 1 genome: Coordinates 0.29 to 0.45
43. Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins
44. Regulation of herpesvirus macromolecular synthesis: Sequential transition of polypeptide synthesis requires functional viral polypeptides
45. Penetration of herpes simplex virus into human epidermoid cells
46. Enveloped viruses: A common mode of membrane fusion?
47. A point mutation within a distinct conserved region of the herpes simplex virus DNA polymerase gene confers drug resistance
48. Herpes simplex keratitis
49. Sp1 binds to promoter sequences and activates herpes simplex virus "immediate-early" gene transcription in vitro
50. Herpes simplex virus glycoprotein D can bind to poliovirus receptor-related protein or herpes virus entry mediator, two structurally unrelated mediators of virus entry
51. HCF-dependent nuclear import of VP16
52. The paramyxovirus fusion protein forms an extremely stable core trimer: Structural parallels to influenza virus haemagglutinin and HIV-1 gp41
53. Heparan sulfate proteoglycan binding by herpes simplex virus type 1 glycoproteins B and C, which differ in their contributions to virus attachment, penetration, and cell-to-cell spread
54. Resistance to antiviral drugs: Although relatively new and poorly understood, viral resistance to drugs is an increasingly significant clinical issue
55. Epidemiology of ocular herpes simplex. Natural history in Rochester, Minn, 1950 through 1982
56. Epidemiology of ocular herpes simplex. Incidence in Rochester, Minn, 1950 through 1982
57. Repression of the α0 gene by ICP4 during a productive herpes simplex virus infection
58. 4 zinc ring finger reveals a requirement for ICP0 in the expression of the essential α27 gene
59. A cobalt complex that selectively disrupts the structure and function of zinc fingers
60. Aberrant intracellular localization of varicella zoster virus regulatory proteins during latency
61. Differentiation between a promoter and regulator regions of herpes simplex virus 1: The functional domains and sequence of a movable α regulator
62. Regulation of α genes of herpes simplex virus: The α27 promoter-thymidine kinase chimera is positively regulated in converted L cells
63. Structural features of the herpes simplex virus alpha-gene 4, 0, and 27 promoter-regulatory sequences which confer alpha-regulation on chimeric thymidine kinase genes
64. Cell-specific kinetics and efficiency of herpes simplex virus type 1 entry are determined by two distinct phases of attachment
65. Cyclosporine A inhibits herpes simplex virus-induced cell fusion but not virus penetration into cells
66. Repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infection
67. Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family
68. Domains of herpes simplex virus 1 glycoprotein B that function in virus penetration, cell-to-cell spread, and cell fusion
69. Variability of herpes simplex virus gL and anti-gL antibodies that inhibit cell fusion but not viral infectivity
70. Occurrence and characterization of acyclovir-resistant herpes simplex virus isolates: Report on a two-year sensitivity screening survey
71. Direct combinatorial interaction between a herpes simplex virus regulatory protein and a cellular octamer-binding factor mediates specific induction of virus immediate-early gene expression
72. Topical CTC-96 accelerates wart growth in rabbits infected with cottontail rabbit papillomavirus
73. Modified entry and syncytium formation by herpes simplex virus type 1 mutants selected for resistance to heparin inhibition
74. The anti-herpes simplex virus activity of n-docosanol includes inhibition of the viral entry process
75. Regulation of alpha genes of HSV: Expression of chimeric genes produced by fusion of thymidine kinase with alpha gene promoters
76. Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsK
77. The role of herpes simplex virus glycoproteins in the virus replication cycle
78. Current concepts and challenges in the prevention and treatment of viral infections in immunocompromised cancer patients
79. Gene-specific trans-activation by the herpes simplex virus type 1 alpha protein ICP27
80. An inquiry into the mechanisms of recurrent herpes infections in man
81. Herpes simplex viruses and their replication
82. -) cell clone resistant to postattachment entry by herpes simplex virus types 1 and 2
83. s11-expressing cell line is resistant to herpes simplex virus infection at a step in viral entry mediated by glycoprotein D
84. Resistance of herpes simplex virus to acycloguanosine: Role of thymidine kinase and DNA polymerase loci
85. Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycans
86. Coiled coils in both intracellular vesicle and viral membrane fusion
87. Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus
88. Shuttling between the nucleus and cytoplasm of the herpes simplex virus type 1 regulatory protein ICP27 mediates the expression of late proteins
89. Entry of alphaherpesviruses into cells
90. Glycoproteins specified by herpes simplex virus
91. Three classes of cell surface receptors for alphaherpesvirus entry
92. Herpesvirus infection in persons infected with human immunodeficiency virus
93. Restricted transcription of the herpes simplex virus genome occurring early after infection and in the presence of metabolic inhibitors
94. HveA (herpesvirus entry mediator A), a coreceptor for herpes simplex virus entry, also participates in virus-induced cell fusion
95. Immunopathogenesis of herpetic ocular disease
96. Antiviral activity of a series of cobalt containing complexes against herpesvirus infection in vitro and in vivo
97. Cyclosporine A resistance of herpes simplex virus-induce "fusion from within" as a phenotypical marker of mutations in the syn 3 locus of the glycoprotein B gene
98. A cell surface protein with herpesvirus entry activity (HveB) confers susceptibility to infection by mutants of herpes simplex virus type 1, herpes simplex virus type 2, and psuedorabies virus
99. Characterization of transcription-deficient temperature-sensitive mutants of herpes simplex virus
100. Structural basis for membrane fusion by enveloped viruses
101. Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry
102. Herpes simplex viruses
103. Antivirals in the context of HIV disease
104. The influence of superoxide scavenging compound CTC 23 on type II collagen-induced arthritis in mice
105. Initial interaction of herpes simplex virus with cells is binding to heparan sulfate
106. Visualization of tegument-capsid interactions and DNA in intact herpes simplex virus type 1 virions
107. Chemical crosslinking of glycoproteins on the envelope of herpes simplex virus