Acute cobalt-induced lung injury and the role of hypoxia-inducible factor 1α in modulating inflammation

Toxicological Sciences

Volumn 116, Issue 2, 2010, Pages 673-681

  Saini, Yogesh ^a,b   Greenwood, Krista K ^a,b   Merrill, Christian ^a   Kim, Kyung Y ^a   Patial, Sonika ^b   Parameswaran, Narayanan ^b   Harkema, Jack R ^b   LaPres, John J ^a,b  

^a Michigan State University   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Cobalt; HIF1 ; Hypoxia; Lung inflammation

Indexed keywords

COBALT; CYTOKINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HIF1A PROTEIN, MOUSE;

AIR POLLUTION; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EOSINOPHIL COUNT; HYPOXIA; IMMUNE RESPONSE; INNATE IMMUNITY; LUNG INJURY; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; TH1 CELL; TH2 CELL; ANIMAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; INFLAMMATION; LUNG; PATHOLOGY; PHYSIOLOGY; TOXICITY;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; COBALT; CYTOKINES; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNITY, INNATE; INFLAMMATION; LUNG; MICE; NEUTROPHIL INFILTRATION;

EID: 77955079523     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq155     Document Type: Article

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