-
1
-
-
1842585605
-
Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes
-
Andrieux L., Langouet S., Fautrel A., Ezan F., Krauser J.A., Savouret J.F., Guengerich F.P., Baffet G., and Guillouzo A. Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes. Mol. Pharmacol. 65 (2004) 934-943
-
(2004)
Mol. Pharmacol.
, vol.65
, pp. 934-943
-
-
Andrieux, L.1
Langouet, S.2
Fautrel, A.3
Ezan, F.4
Krauser, J.A.5
Savouret, J.F.6
Guengerich, F.P.7
Baffet, G.8
Guillouzo, A.9
-
2
-
-
40949083424
-
Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice
-
Arlt V.M., Stiborova M., Henderson C.J., Thiemann M., Frei E., Aimova D., Singh R., Gamboa da Costa G., Schmitz O.J., Farmer P.B., Wolf C.R., and Phillips D.H. Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice. Carcinogenesis 29 (2008) 656-665
-
(2008)
Carcinogenesis
, vol.29
, pp. 656-665
-
-
Arlt, V.M.1
Stiborova, M.2
Henderson, C.J.3
Thiemann, M.4
Frei, E.5
Aimova, D.6
Singh, R.7
Gamboa da Costa, G.8
Schmitz, O.J.9
Farmer, P.B.10
Wolf, C.R.11
Phillips, D.H.12
-
3
-
-
17044423833
-
Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action
-
Baird W.M., Hooven L.A., and Mahadevan B. Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action. Environ. Mol. Mutagen. 45 (2005) 106-114
-
(2005)
Environ. Mol. Mutagen.
, vol.45
, pp. 106-114
-
-
Baird, W.M.1
Hooven, L.A.2
Mahadevan, B.3
-
4
-
-
0031772143
-
Cytochrome P450 1B1: a major P450 isoenzyme in human blood monocytes and macrophage subsets
-
Baron J.M., Zwadlo-Klarwasser G., Jugert F., Hamann W., Rubben A., Mukhtar H., and Merk H.F. Cytochrome P450 1B1: a major P450 isoenzyme in human blood monocytes and macrophage subsets. Biochem. Pharmacol. 56 (1998) 1105-1110
-
(1998)
Biochem. Pharmacol.
, vol.56
, pp. 1105-1110
-
-
Baron, J.M.1
Zwadlo-Klarwasser, G.2
Jugert, F.3
Hamann, W.4
Rubben, A.5
Mukhtar, H.6
Merk, H.F.7
-
5
-
-
0035188023
-
Signaling by environmental polycyclic aromatic hydrocarbons in human lymphocytes
-
Burchiel S.W., and Luster M.I. Signaling by environmental polycyclic aromatic hydrocarbons in human lymphocytes. Clin. Immunol. 98 (2001) 2-10
-
(2001)
Clin. Immunol.
, vol.98
, pp. 2-10
-
-
Burchiel, S.W.1
Luster, M.I.2
-
6
-
-
0035124707
-
Analysis of genetic and epigenetic mechanisms of toxicity: potential roles of toxicogenomics and proteomics in toxicology
-
Burchiel S.W., Knall C.M., Davis II J.W., Paules R.S., Boggs S.E., and Afshari C.A. Analysis of genetic and epigenetic mechanisms of toxicity: potential roles of toxicogenomics and proteomics in toxicology. Toxicol. Sci. 59 (2001) 193-195
-
(2001)
Toxicol. Sci.
, vol.59
, pp. 193-195
-
-
Burchiel, S.W.1
Knall, C.M.2
Davis II, J.W.3
Paules, R.S.4
Boggs, S.E.5
Afshari, C.A.6
-
7
-
-
0033514998
-
Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas
-
Buters J.T., Sakai S., Richter T., Pineau T., Alexander D.L., Savas U., Doehmer J., Ward J.M., Jefcoate C.R., and Gonzalez F.J. Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 1977-1982
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 1977-1982
-
-
Buters, J.T.1
Sakai, S.2
Richter, T.3
Pineau, T.4
Alexander, D.L.5
Savas, U.6
Doehmer, J.7
Ward, J.M.8
Jefcoate, C.R.9
Gonzalez, F.J.10
-
8
-
-
2942577835
-
Suppressive effects of benzo[a]pyrene upon fish immune function: evolutionarily conserved cellular mechanisms of immunotoxicity
-
Carlson E.A., Li Y., and Zelikoff J.T. Suppressive effects of benzo[a]pyrene upon fish immune function: evolutionarily conserved cellular mechanisms of immunotoxicity. Mar. Environ. Res. 58 (2004) 731-734
-
(2004)
Mar. Environ. Res.
, vol.58
, pp. 731-734
-
-
Carlson, E.A.1
Li, Y.2
Zelikoff, J.T.3
-
9
-
-
14744302949
-
Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues
-
Choudhary D., Jansson I., Stoilov I., Sarfarazi M., and Schenkman J.B. Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues. Arch. Biochem. Biophys. 436 (2005) 50-61
-
(2005)
Arch. Biochem. Biophys.
, vol.436
, pp. 50-61
-
-
Choudhary, D.1
Jansson, I.2
Stoilov, I.3
Sarfarazi, M.4
Schenkman, J.B.5
-
10
-
-
0030220509
-
Human T cells are highly sensitive to suppression of mitogenesis by polycyclic aromatic hydrocarbons and this effect is differentially reversed by alpha-naphthoflavone
-
Davila D.R., Romero D.L., and Burchiel S.W. Human T cells are highly sensitive to suppression of mitogenesis by polycyclic aromatic hydrocarbons and this effect is differentially reversed by alpha-naphthoflavone. Toxicol. Appl. Pharmacol. 139 (1996) 333-341
-
(1996)
Toxicol. Appl. Pharmacol.
, vol.139
, pp. 333-341
-
-
Davila, D.R.1
Romero, D.L.2
Burchiel, S.W.3
-
11
-
-
17844398525
-
Modulation of the metabolism and adverse effects of benzo[a]pyrene by a specific antibody: a novel host factor in environmental carcinogenesis?
-
De Buck S.S., Bouche F.B., Brandenburger A., and Muller C.P. Modulation of the metabolism and adverse effects of benzo[a]pyrene by a specific antibody: a novel host factor in environmental carcinogenesis?. Carcinogenesis 26 (2005) 835-844
-
(2005)
Carcinogenesis
, vol.26
, pp. 835-844
-
-
De Buck, S.S.1
Bouche, F.B.2
Brandenburger, A.3
Muller, C.P.4
-
12
-
-
0242594005
-
Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver
-
Galvan N., Jaskula-Sztul R., MacWilliams P.S., Czuprynski C.J., and Jefcoate C.R. Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver. Toxicol. Appl. Pharmacol. 193 (2003) 84-96
-
(2003)
Toxicol. Appl. Pharmacol.
, vol.193
, pp. 84-96
-
-
Galvan, N.1
Jaskula-Sztul, R.2
MacWilliams, P.S.3
Czuprynski, C.J.4
Jefcoate, C.R.5
-
13
-
-
12844287118
-
Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity
-
Galvan N., Teske D.E., Zhou G., Moorthy B., MacWilliams P.S., Czuprynski C.J., and Jefcoate C.R. Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity. Toxicol. Appl. Pharmacol. 202 (2005) 244-257
-
(2005)
Toxicol. Appl. Pharmacol.
, vol.202
, pp. 244-257
-
-
Galvan, N.1
Teske, D.E.2
Zhou, G.3
Moorthy, B.4
MacWilliams, P.S.5
Czuprynski, C.J.6
Jefcoate, C.R.7
-
14
-
-
0019074870
-
Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes
-
Gelboin H.V. Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes. Physiol. Rev. 60 (1980) 1107-1166
-
(1980)
Physiol. Rev.
, vol.60
, pp. 1107-1166
-
-
Gelboin, H.V.1
-
15
-
-
0025181840
-
Zero-length crosslinking procedure with the use of active esters
-
Grabarek Z., and Gergely J. Zero-length crosslinking procedure with the use of active esters. Anal. Biochem. 185 (1990) 131-135
-
(1990)
Anal. Biochem.
, vol.185
, pp. 131-135
-
-
Grabarek, Z.1
Gergely, J.2
-
16
-
-
49049093593
-
Sub-acute administration of benzo[a]pyrene (B[a]P) reduces anxiety-related behaviour in adult mice and modulates regional expression of N-methyl-d-aspartate (NMDA) receptors genes in relevant brain regions
-
Grova N., Schroeder H., Farinelle S., Prodhomme E., Valley A., and Muller C.P. Sub-acute administration of benzo[a]pyrene (B[a]P) reduces anxiety-related behaviour in adult mice and modulates regional expression of N-methyl-d-aspartate (NMDA) receptors genes in relevant brain regions. Chemosphere 73 (2008) S295-302
-
(2008)
Chemosphere
, vol.73
-
-
Grova, N.1
Schroeder, H.2
Farinelle, S.3
Prodhomme, E.4
Valley, A.5
Muller, C.P.6
-
17
-
-
67349287794
-
Modulation of carcinogen bioavailability by immunisation with benzo[a]pyrene-conjugate vaccines
-
Grova N., Prodhomme E.J., Schellenberger M.T., Farinelle S., and Muller C.P. Modulation of carcinogen bioavailability by immunisation with benzo[a]pyrene-conjugate vaccines. Vaccine 27 (2009) 4142-4151
-
(2009)
Vaccine
, vol.27
, pp. 4142-4151
-
-
Grova, N.1
Prodhomme, E.J.2
Schellenberger, M.T.3
Farinelle, S.4
Muller, C.P.5
-
18
-
-
18644375370
-
Cytochrome P450 1B1 mRNA levels in peripheral blood cells and exposure to polycyclic aromatic hydrocarbons in Chinese coke oven workers
-
Hanaoka T., Yamano Y., Pan G., Hara K., Ichiba M., Zhang J., Zhang S., Liu T., Li L., Takahashi K., Kagawa J., and Tsugane S. Cytochrome P450 1B1 mRNA levels in peripheral blood cells and exposure to polycyclic aromatic hydrocarbons in Chinese coke oven workers. Sci. Total. Environ. 296 (2002) 27-33
-
(2002)
Sci. Total. Environ.
, vol.296
, pp. 27-33
-
-
Hanaoka, T.1
Yamano, Y.2
Pan, G.3
Hara, K.4
Ichiba, M.5
Zhang, J.6
Zhang, S.7
Liu, T.8
Li, L.9
Takahashi, K.10
Kagawa, J.11
Tsugane, S.12
-
19
-
-
0027053231
-
Mechanisms by which benzo[a]pyrene, an environmental carcinogen, suppresses B cell lymphopoiesis
-
Hardin J.A., Hinoshita F., and Sherr D.H. Mechanisms by which benzo[a]pyrene, an environmental carcinogen, suppresses B cell lymphopoiesis. Toxicol. Appl. Pharmacol. 117 (1992) 155-164
-
(1992)
Toxicol. Appl. Pharmacol.
, vol.117
, pp. 155-164
-
-
Hardin, J.A.1
Hinoshita, F.2
Sherr, D.H.3
-
21
-
-
4344612128
-
Nicotine conjugate vaccine: is there a right to a smoking future?
-
Hasman A., and Holm S. Nicotine conjugate vaccine: is there a right to a smoking future?. J. Med. Ethics. 30 (2004) 344-345
-
(2004)
J. Med. Ethics.
, vol.30
, pp. 344-345
-
-
Hasman, A.1
Holm, S.2
-
22
-
-
0025893062
-
Benzo-a-pyrene: environmental partitioning and human exposure
-
Hattemer-Frey H.A., and Travis C.C. Benzo-a-pyrene: environmental partitioning and human exposure. Toxicol. Ind. Health 7 (1991) 141-157
-
(1991)
Toxicol. Ind. Health
, vol.7
, pp. 141-157
-
-
Hattemer-Frey, H.A.1
Travis, C.C.2
-
23
-
-
0033591845
-
Tobacco smoke carcinogens and lung cancer
-
Hecht S.S. Tobacco smoke carcinogens and lung cancer. J. Natl. Cancer Inst. 91 (1999) 1194-1210
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 1194-1210
-
-
Hecht, S.S.1
-
24
-
-
0032442156
-
Bone marrow stromal cells constitutively express high levels of cytochrome P4501B1 that metabolize 7,12-dimethylbenz[a]anthracene
-
Heidel S.M., Czuprynski C.J., and Jefcoate C.R. Bone marrow stromal cells constitutively express high levels of cytochrome P4501B1 that metabolize 7,12-dimethylbenz[a]anthracene. Mol. Pharmacol. 54 (1998) 1000-1006
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 1000-1006
-
-
Heidel, S.M.1
Czuprynski, C.J.2
Jefcoate, C.R.3
-
25
-
-
0012692555
-
Immunization of rats reduces nicotine distribution to brain
-
Hieda Y., Keyler D.E., VanDeVoort J.T., Niedbala R.S., Raphael D.E., Ross C.A., and Pentel P.R. Immunization of rats reduces nicotine distribution to brain. Psychopharmacology (Berl) 143 (1999) 150-157
-
(1999)
Psychopharmacology (Berl)
, vol.143
, pp. 150-157
-
-
Hieda, Y.1
Keyler, D.E.2
VanDeVoort, J.T.3
Niedbala, R.S.4
Raphael, D.E.5
Ross, C.A.6
Pentel, P.R.7
-
26
-
-
0033859862
-
Vaccination against nicotine during continued nicotine administration in rats: immunogenicity of the vaccine and effects on nicotine distribution to brain
-
Hieda Y., Keyler D.E., Ennifar S., Fattom A., and Pentel P.R. Vaccination against nicotine during continued nicotine administration in rats: immunogenicity of the vaccine and effects on nicotine distribution to brain. Int. J. Immunopharmacol. 22 (2000) 809-819
-
(2000)
Int. J. Immunopharmacol.
, vol.22
, pp. 809-819
-
-
Hieda, Y.1
Keyler, D.E.2
Ennifar, S.3
Fattom, A.4
Pentel, P.R.5
-
27
-
-
0025993764
-
Humoral recall responses in HIV infection. Levels, specificity, and affinity of antigen-specific IgG
-
Janoff E.N., Hardy W.D., Smith P.D., and Wahl S.M. Humoral recall responses in HIV infection. Levels, specificity, and affinity of antigen-specific IgG. J. Immunol. 147 (1991) 2130-2135
-
(1991)
J. Immunol.
, vol.147
, pp. 2130-2135
-
-
Janoff, E.N.1
Hardy, W.D.2
Smith, P.D.3
Wahl, S.M.4
-
28
-
-
0000252569
-
Highly tumorigenic bay-region diol epoxides from the weak carcinogen benzo[c]phenanthrene
-
Jerina D.M., Sayer J.M., Yagi H., Croisy-Delcey M., Ittah Y., Thakker D.R., Wood A.W., Chang R.L., Levin W., and Conney A.H. Highly tumorigenic bay-region diol epoxides from the weak carcinogen benzo[c]phenanthrene. Adv. Exp. Med. Biol. 136 Pt. A (1981) 501-523
-
(1981)
Adv. Exp. Med. Biol.
, vol.136
, Issue.PART A
, pp. 501-523
-
-
Jerina, D.M.1
Sayer, J.M.2
Yagi, H.3
Croisy-Delcey, M.4
Ittah, Y.5
Thakker, D.R.6
Wood, A.W.7
Chang, R.L.8
Levin, W.9
Conney, A.H.10
-
29
-
-
61949180463
-
Quantification of phase I/II metabolizing enzyme gene expression and polycyclic aromatic hydrocarbon-DNA adduct levels in human prostate
-
John K., Ragavan N., Pratt M.M., Singh P.B., Al-Buheissi S., Matanhelia S.S., Phillips D.H., Poirier M.C., and Martin F.L. Quantification of phase I/II metabolizing enzyme gene expression and polycyclic aromatic hydrocarbon-DNA adduct levels in human prostate. Prostate 69 (2009) 505-519
-
(2009)
Prostate
, vol.69
, pp. 505-519
-
-
John, K.1
Ragavan, N.2
Pratt, M.M.3
Singh, P.B.4
Al-Buheissi, S.5
Matanhelia, S.S.6
Phillips, D.H.7
Poirier, M.C.8
Martin, F.L.9
-
30
-
-
0030778319
-
IgG biosynthesis: no "immunoregulatory feedback"
-
Junghans R.P. IgG biosynthesis: no "immunoregulatory feedback". Blood 90 (1997) 3815-3818
-
(1997)
Blood
, vol.90
, pp. 3815-3818
-
-
Junghans, R.P.1
-
31
-
-
0023239563
-
Suppression of the vitro humoral immune response of mouse splenocytes by benzo(a)pyrene metabolites and inhibition of benzo(a)pyrene-induced immunosuppression by alpha-naphthoflavone
-
Kawabata T.T., and White Jr. K.L. Suppression of the vitro humoral immune response of mouse splenocytes by benzo(a)pyrene metabolites and inhibition of benzo(a)pyrene-induced immunosuppression by alpha-naphthoflavone. Cancer Res. 47 (1987) 2317-2322
-
(1987)
Cancer Res.
, vol.47
, pp. 2317-2322
-
-
Kawabata, T.T.1
White Jr., K.L.2
-
32
-
-
0024469071
-
Benzo(a)pyrene metabolism by murine spleen microsomes
-
Kawabata T.T., and White Jr. K.L. Benzo(a)pyrene metabolism by murine spleen microsomes. Cancer Res. 49 (1989) 5816-5822
-
(1989)
Cancer Res.
, vol.49
, pp. 5816-5822
-
-
Kawabata, T.T.1
White Jr., K.L.2
-
35
-
-
32844473670
-
Effects of a nicotine conjugate vaccine on the acquisition and maintenance of nicotine self-administration in rats
-
LeSage M.G., Keyler D.E., Hieda Y., Collins G., Burroughs D., Le C., and Pentel P.R. Effects of a nicotine conjugate vaccine on the acquisition and maintenance of nicotine self-administration in rats. Psychopharmacology (Berl). 184 (2006) 409-416
-
(2006)
Psychopharmacology (Berl).
, vol.184
, pp. 409-416
-
-
LeSage, M.G.1
Keyler, D.E.2
Hieda, Y.3
Collins, G.4
Burroughs, D.5
Le, C.6
Pentel, P.R.7
-
36
-
-
0030859279
-
Air pollution exposure-DNA adduct dosimetry in humans and rodents: evidence for non-linearity at high doses
-
Lewtas J., Walsh D., Williams R., and Dobias L. Air pollution exposure-DNA adduct dosimetry in humans and rodents: evidence for non-linearity at high doses. Mutat. Res. 378 (1997) 51-63
-
(1997)
Mutat. Res.
, vol.378
, pp. 51-63
-
-
Lewtas, J.1
Walsh, D.2
Williams, R.3
Dobias, L.4
-
37
-
-
0030709320
-
Sensitivity of CYP1A1 mRNA inducibility by dioxin is the same in Cyp1a2(+/+) wild-type and Cyp1a2(-/-) null mutant mice
-
Liang H.C., McKinnon R.A., and Nebert D.W. Sensitivity of CYP1A1 mRNA inducibility by dioxin is the same in Cyp1a2(+/+) wild-type and Cyp1a2(-/-) null mutant mice. Biochem. Pharmacol. 54 (1997) 1127-1131
-
(1997)
Biochem. Pharmacol.
, vol.54
, pp. 1127-1131
-
-
Liang, H.C.1
McKinnon, R.A.2
Nebert, D.W.3
-
38
-
-
22444437907
-
Vaccine pharmacotherapy for the treatment of cocaine dependence
-
Martell B.A., Mitchell E., Poling J., Gonsai K., and Kosten T.R. Vaccine pharmacotherapy for the treatment of cocaine dependence. Biol. Psychiatry 58 (2005) 158-164
-
(2005)
Biol. Psychiatry
, vol.58
, pp. 158-164
-
-
Martell, B.A.1
Mitchell, E.2
Poling, J.3
Gonsai, K.4
Kosten, T.R.5
-
39
-
-
38449103415
-
The vaccine against nicotine-the future for smoking cessation?
-
Mihaltan F. The vaccine against nicotine-the future for smoking cessation?. Pneumologia 56 (2007) 101-103
-
(2007)
Pneumologia
, vol.56
, pp. 101-103
-
-
Mihaltan, F.1
-
40
-
-
0018115719
-
Reduction of respiratory tract binding of benzo[a]pyrene in mice by immunization
-
Moolten F., Capparell N., and Boger E. Reduction of respiratory tract binding of benzo[a]pyrene in mice by immunization. J. Natl. Cancer Inst. 61 (1978) 1347-1349
-
(1978)
J. Natl. Cancer Inst.
, vol.61
, pp. 1347-1349
-
-
Moolten, F.1
Capparell, N.2
Boger, E.3
-
41
-
-
0017836675
-
Induction of antibodies against carcinogenic polycyclic aromatic hydrocarbons
-
Moolten F.L., Capparell N.J., Boger E., and Mahathalang P. Induction of antibodies against carcinogenic polycyclic aromatic hydrocarbons. Nature 272 (1978) 614-616
-
(1978)
Nature
, vol.272
, pp. 614-616
-
-
Moolten, F.L.1
Capparell, N.J.2
Boger, E.3
Mahathalang, P.4
-
42
-
-
0027456898
-
Effects of benzo[a]pyrene on concanavalin A-stimulated human peripheral blood mononuclear cells in vitro: inhibition of proliferation but no effect on parameters related to the G1 phase of the cell cycle
-
Mudzinski S.P. Effects of benzo[a]pyrene on concanavalin A-stimulated human peripheral blood mononuclear cells in vitro: inhibition of proliferation but no effect on parameters related to the G1 phase of the cell cycle. Toxicol. Appl. Pharmacol. 119 (1993) 166-174
-
(1993)
Toxicol. Appl. Pharmacol.
, vol.119
, pp. 166-174
-
-
Mudzinski, S.P.1
-
43
-
-
0015150074
-
Inhibition of chemically induced neoplasia by immunization with antigenic carcinogen-protein conjugate
-
Peck R.M., and Peck E.B. Inhibition of chemically induced neoplasia by immunization with antigenic carcinogen-protein conjugate. Cancer Res. 31 (1971) 1550-1554
-
(1971)
Cancer Res.
, vol.31
, pp. 1550-1554
-
-
Peck, R.M.1
Peck, E.B.2
-
44
-
-
0033957739
-
A nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates its behavioral and cardiovascular effects in rats
-
Pentel P.R., Malin D.H., Ennifar S., Hieda Y., Keyler D.E., Lake J.R., Milstein J.R., Basham L.E., Coy R.T., Moon J.W., Naso R., and Fattom A. A nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates its behavioral and cardiovascular effects in rats. Pharmacol. Biochem. Behav. 65 (2000) 191-198
-
(2000)
Pharmacol. Biochem. Behav.
, vol.65
, pp. 191-198
-
-
Pentel, P.R.1
Malin, D.H.2
Ennifar, S.3
Hieda, Y.4
Keyler, D.E.5
Lake, J.R.6
Milstein, J.R.7
Basham, L.E.8
Coy, R.T.9
Moon, J.W.10
Naso, R.11
Fattom, A.12
-
45
-
-
0023910021
-
Detection of polycyclic aromatic hydrocarbon-DNA adducts in white blood cells of foundry workers
-
Perera F.P., Hemminki K., Young T.L., Brenner D., Kelly G., and Santella R.M. Detection of polycyclic aromatic hydrocarbon-DNA adducts in white blood cells of foundry workers. Cancer Res. 48 (1988) 2288-2291
-
(1988)
Cancer Res.
, vol.48
, pp. 2288-2291
-
-
Perera, F.P.1
Hemminki, K.2
Young, T.L.3
Brenner, D.4
Kelly, G.5
Santella, R.M.6
-
46
-
-
0037292971
-
Cytochrome P450 1B1: a target for inhibition in anticarcinogenesis strategies
-
Peter Guengerich F., Chun Y.J., Kim D., Gillam E.M., and Shimada T. Cytochrome P450 1B1: a target for inhibition in anticarcinogenesis strategies. Mutat. Res. 523-524 (2003) 173-182
-
(2003)
Mutat. Res.
, vol.523-524
, pp. 173-182
-
-
Peter Guengerich, F.1
Chun, Y.J.2
Kim, D.3
Gillam, E.M.4
Shimada, T.5
-
47
-
-
0033565866
-
Polycyclic aromatic hydrocarbons in the diet
-
Phillips D.H. Polycyclic aromatic hydrocarbons in the diet. Mutat. Res. 443 (1999) 139-147
-
(1999)
Mutat. Res.
, vol.443
, pp. 139-147
-
-
Phillips, D.H.1
-
48
-
-
39949085215
-
Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation
-
Podechard N., Lecureur V., Le Ferrec E., Guenon I., Sparfel L., Gilot D., Gordon J.R., Lagente V., and Fardel O. Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation. Toxicol. Lett. 177 (2008) 130-137
-
(2008)
Toxicol. Lett.
, vol.177
, pp. 130-137
-
-
Podechard, N.1
Lecureur, V.2
Le Ferrec, E.3
Guenon, I.4
Sparfel, L.5
Gilot, D.6
Gordon, J.R.7
Lagente, V.8
Fardel, O.9
-
49
-
-
3543129379
-
Chemical-induced DNA damage and human cancer risk
-
Poirier M.C. Chemical-induced DNA damage and human cancer risk. Nat. Rev. Cancer 4 (2004) 630-637
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 630-637
-
-
Poirier, M.C.1
-
50
-
-
46349100716
-
Up-regulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung
-
Pushparajah D.S., Umachandran M., Plant K.E., Plant N., and Ioannides C. Up-regulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung. Mutagenesis 23 (2008) 299-308
-
(2008)
Mutagenesis
, vol.23
, pp. 299-308
-
-
Pushparajah, D.S.1
Umachandran, M.2
Plant, K.E.3
Plant, N.4
Ioannides, C.5
-
51
-
-
0023029866
-
The influence of bile on the bioavailability of polynuclear aromatic hydrocarbons from the rat intestine
-
Rahman A., Barrowman J.A., and Rahimtula A. The influence of bile on the bioavailability of polynuclear aromatic hydrocarbons from the rat intestine. Can. J. Physiol. Pharmacol. 64 (1986) 1214-1218
-
(1986)
Can. J. Physiol. Pharmacol.
, vol.64
, pp. 1214-1218
-
-
Rahman, A.1
Barrowman, J.A.2
Rahimtula, A.3
-
52
-
-
0031149019
-
Depletion of glutathione by benzo(a)pyrene metabolites, ionomycin, thapsigargin, and phorbol myristate in human peripheral blood mononuclear cells
-
Romero D.L., Mounho B.J., Lauer F.T., Born J.L., and Burchiel S.W. Depletion of glutathione by benzo(a)pyrene metabolites, ionomycin, thapsigargin, and phorbol myristate in human peripheral blood mononuclear cells. Toxicol. Appl. Pharmacol. 144 (1997) 62-69
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.144
, pp. 62-69
-
-
Romero, D.L.1
Mounho, B.J.2
Lauer, F.T.3
Born, J.L.4
Burchiel, S.W.5
-
53
-
-
61749090153
-
Polycyclic aromatic hydrocarbon-DNA adducts and survival among women with breast cancer
-
Sagiv S.K., Gaudet M.M., Eng S.M., Abrahamson P.E., Shantakumar S., Teitelbaum S.L., Bell P., Thomas J.A., Neugut A.I., Santella R.M., and Gammon M.D. Polycyclic aromatic hydrocarbon-DNA adducts and survival among women with breast cancer. Environ. Res. 109 (2009) 287-291
-
(2009)
Environ. Res.
, vol.109
, pp. 287-291
-
-
Sagiv, S.K.1
Gaudet, M.M.2
Eng, S.M.3
Abrahamson, P.E.4
Shantakumar, S.5
Teitelbaum, S.L.6
Bell, P.7
Thomas, J.A.8
Neugut, A.I.9
Santella, R.M.10
Gammon, M.D.11
-
54
-
-
0032138169
-
Apoptosis in Daudi human B cells in response to benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol
-
Salas V.M., and Burchiel S.W. Apoptosis in Daudi human B cells in response to benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol. Toxicol. Appl. Pharmacol. 151 (1998) 367-376
-
(1998)
Toxicol. Appl. Pharmacol.
, vol.151
, pp. 367-376
-
-
Salas, V.M.1
Burchiel, S.W.2
-
55
-
-
0022273530
-
Quantitation of exposure to benzo[a]pyrene with monoclonal antibodies
-
Santella R.M., Hsieh L.L., Lin C.D., Viet S., and Weinstein I.B. Quantitation of exposure to benzo[a]pyrene with monoclonal antibodies. Environ. Health Perspect. 62 (1985) 95-99
-
(1985)
Environ. Health Perspect.
, vol.62
, pp. 95-99
-
-
Santella, R.M.1
Hsieh, L.L.2
Lin, C.D.3
Viet, S.4
Weinstein, I.B.5
-
56
-
-
33748809238
-
Nuclear receptors in human immune cells: expression and correlations
-
Schote A.B., Turner J.D., Schiltz J., and Muller C.P. Nuclear receptors in human immune cells: expression and correlations. Mol. Immunol. 44 (2007) 1436-1445
-
(2007)
Mol. Immunol.
, vol.44
, pp. 1436-1445
-
-
Schote, A.B.1
Turner, J.D.2
Schiltz, J.3
Muller, C.P.4
-
57
-
-
63449118032
-
Influence of aryl hydrocarbon- (Ah) receptor and genotoxins on DNA repair gene expression and cell survival of mouse hepatoma cells
-
Schreck I., Chudziak D., Schneider S., Seidel A., Platt K.L., Oesch F., and Weiss C. Influence of aryl hydrocarbon- (Ah) receptor and genotoxins on DNA repair gene expression and cell survival of mouse hepatoma cells. Toxicology 259 (2009) 91-96
-
(2009)
Toxicology
, vol.259
, pp. 91-96
-
-
Schreck, I.1
Chudziak, D.2
Schneider, S.3
Seidel, A.4
Platt, K.L.5
Oesch, F.6
Weiss, C.7
-
58
-
-
0141890076
-
Dose-response studies on the induction of liver cytochromes P4501A1 and 1B1 by polycyclic aromatic hydrocarbons in arylhydrocarbon-responsive C57BL/6J mice
-
Shimada T., Sugie A., Yamada T., Kawazoe H., Hashimoto M., Azuma E., Nakajima T., Inoue K., and Oda Y. Dose-response studies on the induction of liver cytochromes P4501A1 and 1B1 by polycyclic aromatic hydrocarbons in arylhydrocarbon-responsive C57BL/6J mice. Xenobiotica 33 (2003) 957-971
-
(2003)
Xenobiotica
, vol.33
, pp. 957-971
-
-
Shimada, T.1
Sugie, A.2
Yamada, T.3
Kawazoe, H.4
Hashimoto, M.5
Azuma, E.6
Nakajima, T.7
Inoue, K.8
Oda, Y.9
-
59
-
-
0024551156
-
Reduction of intestinal carcinogen absorption by carcinogen-specific secretory immunity
-
Silbart L.K., and Keren D.F. Reduction of intestinal carcinogen absorption by carcinogen-specific secretory immunity. Science 243 (1989) 1462-1464
-
(1989)
Science
, vol.243
, pp. 1462-1464
-
-
Silbart, L.K.1
Keren, D.F.2
-
61
-
-
0030685054
-
Determination of polycyclic aromatic hydrocarbons (PAH) and their metabolites in blood, feces, and urine of rats orally exposed to PAH contaminated soils
-
van Schooten F.J., Moonen E.J., van der Wal L., Levels P., and Kleinjans J.C. Determination of polycyclic aromatic hydrocarbons (PAH) and their metabolites in blood, feces, and urine of rats orally exposed to PAH contaminated soils. Arch. Environ. Contam. Toxicol. 33 (1997) 317-322
-
(1997)
Arch. Environ. Contam. Toxicol.
, vol.33
, pp. 317-322
-
-
van Schooten, F.J.1
Moonen, E.J.2
van der Wal, L.3
Levels, P.4
Kleinjans, J.C.5
-
62
-
-
38149040187
-
The immunogenicity and safety of a nicotine vaccine in smokers and nonsmokers: results of a randomized, placebo-controlled phase 1/2 trial
-
Wagena E.J., de Vos A., Horwith G., and van Schayck C.P. The immunogenicity and safety of a nicotine vaccine in smokers and nonsmokers: results of a randomized, placebo-controlled phase 1/2 trial. Nicotine Tob. Res. 10 (2008) 213-218
-
(2008)
Nicotine Tob. Res.
, vol.10
, pp. 213-218
-
-
Wagena, E.J.1
de Vos, A.2
Horwith, G.3
van Schayck, C.P.4
-
63
-
-
84886602467
-
High mutagenicity and toxicity of a diol epoxide derived from benzo(a)pyrene
-
Wislocki P.G., Wood A.W., Chang R.L., Levin W., Yagi H., Hernandez O., Jerina D.M., and Conney A.H. High mutagenicity and toxicity of a diol epoxide derived from benzo(a)pyrene. Biochem. Biophys. Res. Commun. 68 (1976) 1006-1012
-
(1976)
Biochem. Biophys. Res. Commun.
, vol.68
, pp. 1006-1012
-
-
Wislocki, P.G.1
Wood, A.W.2
Chang, R.L.3
Levin, W.4
Yagi, H.5
Hernandez, O.6
Jerina, D.M.7
Conney, A.H.8
-
64
-
-
0028924814
-
A critical appraisal of intratracheal instillation of benzo[a]pyrene to Syrian golden hamsters as a model in respiratory tract carcinogenesis
-
Wolterbeek A.P., Schoevers E.J., Rutten A.A., and Feron V.J. A critical appraisal of intratracheal instillation of benzo[a]pyrene to Syrian golden hamsters as a model in respiratory tract carcinogenesis. Cancer Lett. 89 (1995) 107-116
-
(1995)
Cancer Lett.
, vol.89
, pp. 107-116
-
-
Wolterbeek, A.P.1
Schoevers, E.J.2
Rutten, A.A.3
Feron, V.J.4
-
65
-
-
0006071558
-
Distribution and binding pattern of benzo(a)pyrene in rat liver, lung and kidney constituents after oral administration
-
Yamazaki H., Terada M., Tsuboi A., Matsubara C., Hata T., and Kakiuchi Y. Distribution and binding pattern of benzo(a)pyrene in rat liver, lung and kidney constituents after oral administration. Toxicol. Environ. Chem. 15 (1987) 71-81
-
(1987)
Toxicol. Environ. Chem.
, vol.15
, pp. 71-81
-
-
Yamazaki, H.1
Terada, M.2
Tsuboi, A.3
Matsubara, C.4
Hata, T.5
Kakiuchi, Y.6
-
66
-
-
77957177977
-
Polycyclic aromatic hydrocarbons decrease intracellular glutathione levels in the A20.1 murine B cell lymphoma
-
Yuan J.W., Krieger J.A., Maples K.R., Born J.L., and Burchiel S.W. Polycyclic aromatic hydrocarbons decrease intracellular glutathione levels in the A20.1 murine B cell lymphoma. Fundam. Appl. Toxicol. 23 (1994) 336-341
-
(1994)
Fundam. Appl. Toxicol.
, vol.23
, pp. 336-341
-
-
Yuan, J.W.1
Krieger, J.A.2
Maples, K.R.3
Born, J.L.4
Burchiel, S.W.5
-
67
-
-
0031787207
-
Immunohistochemical detection of polycyclic aromatic hydrocarbon-DNA damage in human blood vessels of smokers and non-smokers
-
Zhang Y.J., Weksler B.B., Wang L., Schwartz J., and Santella R.M. Immunohistochemical detection of polycyclic aromatic hydrocarbon-DNA damage in human blood vessels of smokers and non-smokers. Atherosclerosis 140 (1998) 325-331
-
(1998)
Atherosclerosis
, vol.140
, pp. 325-331
-
-
Zhang, Y.J.1
Weksler, B.B.2
Wang, L.3
Schwartz, J.4
Santella, R.M.5
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