메뉴 건너뛰기




Volumn 18, Issue 1, 2012, Pages 44-54

Host CD25 +CD4 +Foxp3 + Regulatory T Cells Primed by anti-CD137 mAbs Inhibit Graft-versus-Host Disease

Author keywords

CD137; GVHD; Regulatory T cells

Indexed keywords

CD137 ANTIBODY; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

EID: 84855452270     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2011.09.004     Document Type: Article
Times cited : (15)

References (41)
  • 1
    • 0033805121 scopus 로고    scopus 로고
    • Revisiting graft-versus-host disease models of autoimmunity: new insights in immune regulatory processes
    • Murphy W.J. Revisiting graft-versus-host disease models of autoimmunity: new insights in immune regulatory processes. JClin Invest 2000, 106:745-747.
    • (2000) JClin Invest , vol.106 , pp. 745-747
    • Murphy, W.J.1
  • 2
    • 33645988549 scopus 로고    scopus 로고
    • + T cell priming through invivo ligation of glucocorticoid-induced TNF receptor
    • + T cell priming through invivo ligation of glucocorticoid-induced TNF receptor. JImmunol 2006, 176:5223-5231.
    • (2006) JImmunol , vol.176 , pp. 5223-5231
    • Kim, J.1    Choi, W.S.2    Kang, H.3
  • 3
    • 58149193839 scopus 로고    scopus 로고
    • + T cell tolerance through invivo ligation of CD40 results in inhibition of chronic graft-versus-host disease and complete donor cell engraftment
    • + T cell tolerance through invivo ligation of CD40 results in inhibition of chronic graft-versus-host disease and complete donor cell engraftment. JImmunol 2008, 181:7380-7389.
    • (2008) JImmunol , vol.181 , pp. 7380-7389
    • Kim, J.1    Park, K.2    Kim, H.J.3
  • 4
    • 0034327197 scopus 로고    scopus 로고
    • Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions
    • Blazar B.R., Lees C.J., Martin P.J., et al. Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions. JImmunol 2000, 165:4901-4909.
    • (2000) JImmunol , vol.165 , pp. 4901-4909
    • Blazar, B.R.1    Lees, C.J.2    Martin, P.J.3
  • 5
    • 0035881968 scopus 로고    scopus 로고
    • + T cells in mice conditioned with fractionated lymphoid irradiation protects against graft-versus-host disease: " natural suppressor" cells
    • + T cells in mice conditioned with fractionated lymphoid irradiation protects against graft-versus-host disease: " natural suppressor" cells. J Immunol 2001, 167:2087-2096.
    • (2001) J Immunol , vol.167 , pp. 2087-2096
    • Lan, F.1    Zeng, D.2    Higuchi, M.3    Huie, P.4    Higgins, J.P.5    Strober, S.6
  • 9
    • 80051944092 scopus 로고    scopus 로고
    • Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation
    • Wing K., Yamaguchi T., Sakaguchi S. Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation. Trends Immunol 2011, 32:428-433.
    • (2011) Trends Immunol , vol.32 , pp. 428-433
    • Wing, K.1    Yamaguchi, T.2    Sakaguchi, S.3
  • 10
    • 0030472390 scopus 로고    scopus 로고
    • Transplantation of polarized type 2 donor T cells reduces mortality caused by experimental graft-versus-host disease
    • Krenger W., Cooke K.R., Crawford J.M., et al. Transplantation of polarized type 2 donor T cells reduces mortality caused by experimental graft-versus-host disease. Transplantation 1996, 62:1278-1285.
    • (1996) Transplantation , vol.62 , pp. 1278-1285
    • Krenger, W.1    Cooke, K.R.2    Crawford, J.M.3
  • 11
    • 0030861750 scopus 로고    scopus 로고
    • Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines
    • Hill G.R., Crawford J.M., Cooke K.R., Brinson Y.S., Pan L., Ferrara J.L. Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines. Blood 1997, 90:3204-3213.
    • (1997) Blood , vol.90 , pp. 3204-3213
    • Hill, G.R.1    Crawford, J.M.2    Cooke, K.R.3    Brinson, Y.S.4    Pan, L.5    Ferrara, J.L.6
  • 13
    • 34249689632 scopus 로고    scopus 로고
    • CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype
    • Zhu Y., Zhu G., Luo L., Flies A.S., Chen L. CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype. Blood 2007, 109:4882-4889.
    • (2007) Blood , vol.109 , pp. 4882-4889
    • Zhu, Y.1    Zhu, G.2    Luo, L.3    Flies, A.S.4    Chen, L.5
  • 14
    • 77950403194 scopus 로고    scopus 로고
    • CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells
    • Narazaki H., Zhu Y., Luo L., Zhu G., Chen L. CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells. Blood 2010, 115:1941-1948.
    • (2010) Blood , vol.115 , pp. 1941-1948
    • Narazaki, H.1    Zhu, Y.2    Luo, L.3    Zhu, G.4    Chen, L.5
  • 15
    • 22344434572 scopus 로고    scopus 로고
    • IFN-γ production by alloantigen-reactive regulatory T cells is important for their regulatory function invivo
    • Sawitzki B., Kingsley C.I., Oliverira V., Karim M., Herber M., Wood K.J. IFN-γ production by alloantigen-reactive regulatory T cells is important for their regulatory function invivo. J Exp Med 2005, 201:1925-1935.
    • (2005) J Exp Med , vol.201 , pp. 1925-1935
    • Sawitzki, B.1    Kingsley, C.I.2    Oliverira, V.3    Karim, M.4    Herber, M.5    Wood, K.J.6
  • 16
    • 77957226847 scopus 로고    scopus 로고
    • Effects of low-dose radiation on the immune system of mice after total-body irradiation
    • Bogdándi E.N., Balogh A., Felgyinszki N., et al. Effects of low-dose radiation on the immune system of mice after total-body irradiation. Radiat Res 2010, 174:480-489.
    • (2010) Radiat Res , vol.174 , pp. 480-489
    • Bogdándi, E.N.1    Balogh, A.2    Felgyinszki, N.3
  • 18
    • 0036467421 scopus 로고    scopus 로고
    • Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis
    • Sun Y., Sun Y., Lin X., et al. Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis. J Immunol 2002, 168:1457-1465.
    • (2002) J Immunol , vol.168 , pp. 1457-1465
    • Sun, Y.1    Sun, Y.2    Lin, X.3
  • 19
    • 33645498741 scopus 로고    scopus 로고
    • CD137-mediated immunotherapy for allergic asthma
    • Polte T., Foell J., Werner C., et al. CD137-mediated immunotherapy for allergic asthma. J Clin Invest 2006, 116:1025-1036.
    • (2006) J Clin Invest , vol.116 , pp. 1025-1036
    • Polte, T.1    Foell, J.2    Werner, C.3
  • 20
    • 7044261952 scopus 로고    scopus 로고
    • 4-1BB-mediated immunotherapy of rheumatoid arthritis
    • Seo S.K., Choi J.H., Kim Y.H., et al. 4-1BB-mediated immunotherapy of rheumatoid arthritis. Nat Med 2004, 10:1088-1094.
    • (2004) Nat Med , vol.10 , pp. 1088-1094
    • Seo, S.K.1    Choi, J.H.2    Kim, Y.H.3
  • 21
    • 0036913169 scopus 로고    scopus 로고
    • Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease
    • Sun Y., Chen H.M., Subudhi S.K., et al. Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease. Nat Med 2002, 8:1405-1413.
    • (2002) Nat Med , vol.8 , pp. 1405-1413
    • Sun, Y.1    Chen, H.M.2    Subudhi, S.K.3
  • 22
    • 0038312910 scopus 로고    scopus 로고
    • CD137 costimulatory Tcell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice
    • Foell J., Strahotin S., O'Neil S.P., et al. CD137 costimulatory Tcell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice. J Clin Invest 2003, 111:1505-1518.
    • (2003) J Clin Invest , vol.111 , pp. 1505-1518
    • Foell, J.1    Strahotin, S.2    O'Neil, S.P.3
  • 23
    • 34547125361 scopus 로고    scopus 로고
    • Costimulatory molecule-targeted immunotherapy of cutaneous graft-versus-host disease
    • Kim J., Kim H.J., Park K., et al. Costimulatory molecule-targeted immunotherapy of cutaneous graft-versus-host disease. Blood 2007, 110:776-782.
    • (2007) Blood , vol.110 , pp. 776-782
    • Kim, J.1    Kim, H.J.2    Park, K.3
  • 24
    • 33947696816 scopus 로고    scopus 로고
    • Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice
    • Niu L., Strahotin S., Hewes B., et al. Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice. J Immunol 2007, 178:4194-4213.
    • (2007) J Immunol , vol.178 , pp. 4194-4213
    • Niu, L.1    Strahotin, S.2    Hewes, B.3
  • 25
    • 67449126825 scopus 로고    scopus 로고
    • Hypercostimulation through 4-1BB distorts homeostasis of immune cells
    • Lee S.W., Salek-Ardakani S., Mittler R.S., Croft M. Hypercostimulation through 4-1BB distorts homeostasis of immune cells. JImmunol 2009, 182:6753-6762.
    • (2009) JImmunol , vol.182 , pp. 6753-6762
    • Lee, S.W.1    Salek-Ardakani, S.2    Mittler, R.S.3    Croft, M.4
  • 26
    • 0038752591 scopus 로고    scopus 로고
    • Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming
    • Granucci F., Feau S., Angeli V., Trottein F., Ricciardi-Castagnoli P. Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming. J Immunol 2003, 170:5075-5081.
    • (2003) J Immunol , vol.170 , pp. 5075-5081
    • Granucci, F.1    Feau, S.2    Angeli, V.3    Trottein, F.4    Ricciardi-Castagnoli, P.5
  • 27
    • 79954559096 scopus 로고    scopus 로고
    • T-cell tolerance and the multi-functional role of IL-2R signaling in T-regulatory cells
    • Cheng G., Yu A., Malek T.R. T-cell tolerance and the multi-functional role of IL-2R signaling in T-regulatory cells. Immunol Rev 2011, 241:6376.
    • (2011) Immunol Rev , vol.241 , pp. 6376
    • Cheng, G.1    Yu, A.2    Malek, T.R.3
  • 28
    • 43049174722 scopus 로고    scopus 로고
    • Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
    • Tang Q., Adams J.Y., Penaranda C., et al. Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity 2008, 28:687-697.
    • (2008) Immunity , vol.28 , pp. 687-697
    • Tang, Q.1    Adams, J.Y.2    Penaranda, C.3
  • 29
    • 33645465526 scopus 로고    scopus 로고
    • Selective stimulation of T cell subsets with antibody-cytokine immune complexes
    • Boyman O., Kovar M., Rubinstein M.P., Surh C.D., Sprent J. Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science 2006, 311:1924-1927.
    • (2006) Science , vol.311 , pp. 1924-1927
    • Boyman, O.1    Kovar, M.2    Rubinstein, M.P.3    Surh, C.D.4    Sprent, J.5
  • 30
    • 76649145452 scopus 로고    scopus 로고
    • IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25
    • Létourneau S., van Leeuwen E.M., Krieg C., et al. IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25. Proc Natl Acad Sci USA 2010, 107:2171-2176.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2171-2176
    • Létourneau, S.1    van Leeuwen, E.M.2    Krieg, C.3
  • 31
    • 65549091509 scopus 로고    scopus 로고
    • Invivo expansion of Treg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of isletallografts without immunosuppression
    • Webster K.E., Walters S., Kohler R.E., et al. Invivo expansion of Treg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of isletallografts without immunosuppression. J Exp Med 2009, 206:751-760.
    • (2009) J Exp Med , vol.206 , pp. 751-760
    • Webster, K.E.1    Walters, S.2    Kohler, R.E.3
  • 32
    • 77956257716 scopus 로고    scopus 로고
    • L-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells
    • Grinberg-Bleyer Y., Baeyens A., You S., et al. L-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells. J Exp Med 2010, 207:1871-1878.
    • (2010) J Exp Med , vol.207 , pp. 1871-1878
    • Grinberg-Bleyer, Y.1    Baeyens, A.2    You, S.3
  • 34
    • 20444403047 scopus 로고    scopus 로고
    • Peptide-specific CD8 T regulatory cells use IFN-γ to elaborate TGF-β-based suppression
    • Myers L., Croft M., Kwon B.S., Mittler R.S., Vella A.T. Peptide-specific CD8 T regulatory cells use IFN-γ to elaborate TGF-β-based suppression. J Immunol 2005, 174:7625-7632.
    • (2005) J Immunol , vol.174 , pp. 7625-7632
    • Myers, L.1    Croft, M.2    Kwon, B.S.3    Mittler, R.S.4    Vella, A.T.5
  • 35
    • 77949352851 scopus 로고    scopus 로고
    • CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice
    • Jeon H.J., Choi J.H., Jung I.H., et al. CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice. Circulation 2010, 121:1124-1133.
    • (2010) Circulation , vol.121 , pp. 1124-1133
    • Jeon, H.J.1    Choi, J.H.2    Jung, I.H.3
  • 36
    • 0037025943 scopus 로고    scopus 로고
    • + regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • + regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J Exp Med 2002, 196:389-399.
    • (2002) J Exp Med , vol.196 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Fathamn, C.G.4    Strober, S.5
  • 37
    • 0031821875 scopus 로고    scopus 로고
    • + immunoregulatory T cells suppress polyclonal T cell activation invitro by inhibiting interleukin 2 production
    • + immunoregulatory T cells suppress polyclonal T cell activation invitro by inhibiting interleukin 2 production. J Exp Med 1998, 188:287-296.
    • (1998) J Exp Med , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 39
    • 0033985780 scopus 로고    scopus 로고
    • + immunoregulatory T cells is antigen nonspecific
    • + immunoregulatory T cells is antigen nonspecific. J Immunol 2000, 164:183-190.
    • (2000) J Immunol , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 40
    • 59349103120 scopus 로고    scopus 로고
    • Induction of lethal graft-versus-host disease by anti-CD137 monoclonal antibody in mice prone to chronic graft-versus-host disease
    • Kim W., Kim J., Jung D., et al. Induction of lethal graft-versus-host disease by anti-CD137 monoclonal antibody in mice prone to chronic graft-versus-host disease. Biol Blood Marrow Transplant 2009, 15:306-314.
    • (2009) Biol Blood Marrow Transplant , vol.15 , pp. 306-314
    • Kim, W.1    Kim, J.2    Jung, D.3
  • 41
    • 78149247315 scopus 로고    scopus 로고
    • Intervention with costimulatory pathways as a therapeutic approach for graft-versus-host disease
    • Kwon B. Intervention with costimulatory pathways as a therapeutic approach for graft-versus-host disease. Exp Mol Med 2010, 42:671-683.
    • (2010) Exp Mol Med , vol.42 , pp. 671-683
    • Kwon, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.