-
1
-
-
0028353492
-
The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
-
DOI 10.1016/0092-8674(94)90372-7
-
Smith CA, Farrah T, Goodwin RG. The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell. 1994;76(6):959-962. (Pubitemid 24106376)
-
(1994)
Cell
, vol.76
, Issue.6
, pp. 959-962
-
-
Smith, C.A.1
Farrah, T.2
Goodwin, R.G.3
-
2
-
-
0028306175
-
Tumor necrosis factor receptor superfamily members and their ligands
-
DOI 10.1016/0952-7915(94)90119-8
-
Armitage RJ. Tumor necrosis factor receptor superfamily members and their ligands. Curr Opin Immunol. 1994;6(3):407-413. (Pubitemid 24188489)
-
(1994)
Current Opinion in Immunology
, vol.6
, Issue.3
, pp. 407-413
-
-
Armitage, R.J.1
-
3
-
-
0141609073
-
Co-stimulatory members of the TNFR family: Keys to effective T-cell immunity?
-
Croft M. Co-stimulatory members of the TNFR family: keys to effective T-cell immunity? Nat Rev Immunol. 2003;3(8):609-620. (Pubitemid 37328664)
-
(2003)
Nature Reviews Immunology
, vol.3
, Issue.8
, pp. 609-620
-
-
Croft, M.1
-
4
-
-
0035057630
-
CD137 expression in tumor vessel walls: High correlation with malignant tumors
-
DOI 10.1309/E343-KMYX-W3Y2-10KY
-
Broll K, Richter G, Pauly S, Hofstaedter F, Schwarz H. CD137 expression in tumor vessel walls: high correlation with malignant tumors. Am J Clin Pathol. 2001;115(4):543-549. (Pubitemid 32275946)
-
(2001)
American Journal of Clinical Pathology
, vol.115
, Issue.4
, pp. 543-549
-
-
Broll, K.1
Richter, G.2
Pauly, S.3
Hofstaedter, F.4
Schwarz, H.5
-
5
-
-
0036838689
-
4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1
-
Lee HW, Park SJ, Choi BK, Kim HH, Nam KO, Kwon BS. 4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1. J Immunol. 2002;169(9):4882-4888.
-
(2002)
J Immunol
, vol.169
, Issue.9
, pp. 4882-4888
-
-
Lee, H.W.1
Park, S.J.2
Choi, B.K.3
Kim, H.H.4
Nam, K.O.5
Kwon, B.S.6
-
6
-
-
0036569392
-
Cutting edge: Expression of functional CD137 receptor by dendritic cells
-
Wilcox RA, Chapoval AI, Gorski KS, et al. Cutting edge: expression of functional CD137 receptor by dendritic cells. J Immunol. 2002;168(9):4262-4267. (Pubitemid 34441322)
-
(2002)
Journal of Immunology
, vol.168
, Issue.9
, pp. 4262-4267
-
-
Wilcox, R.A.1
Chapoval, A.I.2
Gorski, K.S.3
Otsuji, M.4
Shin, T.5
Flies, D.B.6
Tamada, K.7
Mittler, R.S.8
Tsuchiya, H.9
Pardoll, D.M.10
Chen, L.11
-
7
-
-
0032535119
-
NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies
-
DOI 10.1006/cimm.1998.1396
-
Melero I, Johnston JV, Shufford WW, Mittler RS, Chen L. NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies. Cell Immunol. 1998;190(2):167-172. (Pubitemid 29011104)
-
(1998)
Cellular Immunology
, vol.190
, Issue.2
, pp. 167-172
-
-
Melero, I.1
Johnston, J.V.2
Shufford, W.W.3
Mittler, R.S.4
Chen, L.5
-
8
-
-
0033954331
-
CD137 (ILA/4-1BB), expressed by primary human monocytes, induces monocyte activation and apoptosis of B lymphocytes
-
Kienzle G, von Kempis J. CD137 (ILA/4-1BB), expressed by primary human monocytes, induces monocyte activation and apoptosis of B lymphocytes. Int Immunol. 2000;12(1):73-82. (Pubitemid 30045414)
-
(2000)
International Immunology
, vol.12
, Issue.1
, pp. 73-82
-
-
Kienzle, G.1
Von Kempis, J.2
-
9
-
-
0033229705
-
CD137 induces proliferation and endomitosis in monocytes
-
Langstein J, Michel J, Schwarz H. CD137 induces proliferation and endomitosis in monocytes. Blood. 1999;94(9):3161-3168. (Pubitemid 29512724)
-
(1999)
Blood
, vol.94
, Issue.9
, pp. 3161-3168
-
-
Langstein, J.1
Michel, J.2
Schwarz, H.3
-
10
-
-
0031007143
-
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
-
DOI 10.1038/nm0697-682
-
Melero I, Shuford WW, Newby SA, et al. Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. Nat Med. 1997;3(6):682-685. (Pubitemid 27264981)
-
(1997)
Nature Medicine
, vol.3
, Issue.6
, pp. 682-685
-
-
Melero, I.1
Shuford, W.W.2
Newby, S.A.3
Aruffo, A.4
Ledbetter, J.A.5
Hellstrom, K.E.6
Mittler, R.S.7
Chen, L.8
-
11
-
-
13444270323
-
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity
-
Hirano F, Kaneko K, Tamura H, et al. Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity. Cancer Res. 2005;65(3):1089-1096. (Pubitemid 40216472)
-
(2005)
Cancer Research
, vol.65
, Issue.3
, pp. 1089-1096
-
-
Hirano, F.1
Kaneko, K.2
Tamura, H.3
Dong, H.4
Wang, S.5
Ichikawa, M.6
Rietz, C.7
Flies, D.B.8
Lau, J.S.9
Zhu, G.10
Tamada, K.11
Chen, L.12
-
12
-
-
0034162569
-
4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination
-
Tan JT, Whitmire JK, Murali-Krishna K, et al. 4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination. J Immunol. 2000;164(5):2320-2325. (Pubitemid 30115458)
-
(2000)
Journal of Immunology
, vol.164
, Issue.5
, pp. 2320-2325
-
-
Tan, J.T.1
Whitmire, J.K.2
Murali-Krishna, K.3
Ahmed, R.4
Altman, J.D.5
Mittler, R.S.6
Sette, A.7
Pearson, T.C.8
Larsen, C.P.9
-
13
-
-
30444442143
-
Renewed interest in cancer immunotherapy with the tumor necrosis factor superfamily molecules
-
DOI 10.1007/s00262-005-0081-y
-
Tamada K, Chen L. Renewed interest in cancer immunotherapy with the tumor necrosis factor superfamily molecules. Cancer Immunol Immunother. 2006;55(4):355-362. (Pubitemid 43076887)
-
(2006)
Cancer Immunology, Immunotherapy
, vol.55
, Issue.4
, pp. 355-362
-
-
Tamada, K.1
Chen, L.2
-
14
-
-
0346336784
-
+ cytolytic T lymphocytes in vivo
-
DOI 10.1182/blood-2003-06-2184
-
Wilcox RA, Tamada K, Flies DB, et al. Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo. Blood. 2004;103(1):177-184. (Pubitemid 38029936)
-
(2004)
Blood
, vol.103
, Issue.1
, pp. 177-184
-
-
Wilcox, R.A.1
Tamada, K.2
Flies, D.B.3
Zhu, G.4
Chapoval, A.I.5
Blazar, B.R.6
Kast, W.M.7
Chen, L.8
-
15
-
-
55949113750
-
Phase I study of BMS-663513, a fully human anti-CD137 agonist monoclonal antibody, in patients (pts) with advanced cancer (CA) [abstract]
-
Sznol M, Hodi FS, Margolin K, et al. Phase I study of BMS-663513, a fully human anti-CD137 agonist monoclonal antibody, in patients (pts) with advanced cancer (CA) [abstract]. J Clin Oncol (Meeting Abstracts). 2008;26(15;suppl): 3007.
-
(2008)
J Clin Oncol (Meeting Abstracts)
, vol.26
, Issue.15 SUPPL.
, pp. 3007
-
-
Sznol, M.1
Hodi, F.S.2
Margolin, K.3
-
16
-
-
34249689632
-
CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype
-
DOI 10.1182/blood-2006-10-043463
-
Zhu Y, Zhu G, Luo L, Flies AS, Chen L. CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype. Blood. 2007;109(11):4882-4889. (Pubitemid 46827785)
-
(2007)
Blood
, vol.109
, Issue.11
, pp. 4882-4889
-
-
Zhu, Y.1
Zhu, G.2
Luo, L.3
Flies, A.S.4
Chen, L.5
-
17
-
-
33745074981
-
+ T cells
-
DOI 10.1111/j.0105-2896.2006.00382.x
-
Mescher MF, Curtsinger JM, Agarwal P, et al. Signals required for programming effector and memory development by CD8+ T cells. Immunol Rev. 2006;211:81-92. (Pubitemid 43882963)
-
(2006)
Immunological Reviews
, vol.211
, pp. 81-92
-
-
Mescher, M.F.1
Curtsinger, J.M.2
Agarwal, P.3
Casey, K.A.4
Gerner, M.5
Hammerbeck, C.D.6
Popescu, F.7
Xiao, Z.8
-
18
-
-
0022473607
-
A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes
-
Rosenberg SA, Spiess P, Lafreniere R. A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes. Science. 1986;233(4770):1318-1321.
-
(1986)
Science
, vol.233
, Issue.4770
, pp. 1318-1321
-
-
Rosenberg, S.A.1
Spiess, P.2
Lafreniere, R.3
-
19
-
-
0024166189
-
Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma: A preliminary report
-
Rosenberg SA, Packard BS, Aebersold PM, et al. Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma: a preliminary report. N Engl J Med. 1988;319(25):1676-1680.
-
(1988)
N Engl J Med
, vol.319
, Issue.25
, pp. 1676-1680
-
-
Rosenberg, S.A.1
Packard, B.S.2
Aebersold, P.M.3
-
20
-
-
27544506907
-
High frequencies of functional tumor-reactive T cells in bone marrow and blood of pancreatic cancer patients
-
DOI 10.1158/0008-5472.CAN-05-1098
-
Schmitz-Winnenthal FH, Volk C, Z'Graggen K, et al. High frequencies of functional tumor-reactive T cells in bone marrow and blood of pancreatic cancer patients. Cancer Res. 2005;65(21):10079-10087. (Pubitemid 41541490)
-
(2005)
Cancer Research
, vol.65
, Issue.21
, pp. 10079-10087
-
-
Schmitz-Winnenthal, F.H.1
Volk, C.2
Z'Graggen, K.3
Galindo, L.4
Nummer, D.5
Ziouta, Y.6
Bucur, M.7
Weitz, J.8
Schirrmacher, V.9
Buchler, M.W.10
Beckhove, P.11
-
21
-
-
34247849183
-
Effector and memory CTL differentiation
-
Williams MA, Bevan MJ. Effector and memory CTL differentiation. Annu Rev Immunol. 2007;25:171-192.
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 171-192
-
-
Williams, M.A.1
Bevan, M.J.2
-
22
-
-
0032479138
-
Antigen loss variants of a murine renal cell carcinoma: Implications for tumor vaccination
-
DOI 10.1002/(SICI)1097-0215(19980703)77:1<114::AID-IJC18>3.0.CO;2-E
-
Kerkmann-Tucek A, Banat GA, Cochlovius B, Zoller M. Antigen loss variants of a murine renal cell carcinoma: implications for tumor vaccination. Int J Cancer. 1998;77(1):114-122. (Pubitemid 28308560)
-
(1998)
International Journal of Cancer
, vol.77
, Issue.1
, pp. 114-122
-
-
Kerkmann-Tucek, A.1
Banat, G.-A.2
Cochlovius, B.3
Zoller, M.4
-
23
-
-
0036195860
-
Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors
-
DOI 10.1172/JCI200214184
-
Wilcox RA, Flies DB, Zhu G, et al. Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors. J Clin Invest. 2002;109(5):651-659. (Pubitemid 34204844)
-
(2002)
Journal of Clinical Investigation
, vol.109
, Issue.5
, pp. 651-659
-
-
Wilcox, R.A.1
Flies, D.B.2
Zhu, G.3
Johnson, A.J.4
Tamada, K.5
Chapoval, A.I.6
Strome, S.E.7
Pease, L.R.8
Chen, L.9
-
24
-
-
18644370691
-
Detection of peptide-specific CTL-precursors in peripheral blood lymphocytes of cancer patients
-
DOI 10.1038/sj.bjc.6600548
-
Maeda Y, Hida N, Niiya F, et al. Detection of peptide-specific CTL-precursors in peripheral blood lymphocytes of cancer patients. Br J Cancer. 2002;87(7):796-804. (Pubitemid 35178759)
-
(2002)
British Journal of Cancer
, vol.87
, Issue.7
, pp. 796-804
-
-
Maeda, Y.1
Hida, N.2
Niiya, F.3
Katagiri, K.4
Harada, M.5
Yamana, H.6
Kamura, T.7
Takahashi, M.8
Sato, Y.9
Todo, S.10
Itoh, K.11
-
25
-
-
0038312910
-
1 mice
-
DOI 10.1172/JCI200317662
-
Foell J, Strahotin S, O'Neil SP, et al. CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice. J Clin Invest. 2003;111(10):1505-1518. (Pubitemid 38063283)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.10
, pp. 1505-1518
-
-
Foell, J.1
Strahotin, S.2
O'Neil, S.P.3
McCausland, M.M.4
Suwyn, C.5
Haber, M.6
Chander, P.N.7
Bapat, A.S.8
Yan, X.-J.9
Chiorazzi, N.10
Hoffmann, M.K.11
Mittler, R.S.12
-
26
-
-
33947696816
-
Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice
-
Niu L, Strahotin S, Hewes B, et al. Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice. J Immunol. 2007;178(7):4194-4213. (Pubitemid 46492370)
-
(2007)
Journal of Immunology
, vol.178
, Issue.7
, pp. 4194-4213
-
-
Niu, L.1
Strahotin, S.2
Hewes, B.3
Zhang, B.4
Zhang, Y.5
Archer, D.6
Spencer, T.7
Dillehay, D.8
Kwon, B.9
Chen, L.10
Vella, A.T.11
Mittler, R.S.12
-
27
-
-
33845479263
-
Cytokine storm and an anti-CD28 monoclonal antibody
-
author reply 2593-2594.
-
Corry DB, Lewis DE. Cytokine storm and an anti-CD28 monoclonal antibody. N Engl J Med. 2006;355(24):2592, author reply 2593-2594.
-
(2006)
N Engl J Med
, vol.355
, Issue.24
, pp. 2592
-
-
Corry, D.B.1
Lewis, D.E.2
-
28
-
-
14244269194
-
Biological activities of reverse signal transduction through CD137 ligand
-
DOI 10.1189/jlb.0904558
-
Schwarz H. Biological activities of reverse signal transduction through CD137 ligand. J Leukoc Biol. 2005;77(3):281-286. (Pubitemid 40289556)
-
(2005)
Journal of Leukocyte Biology
, vol.77
, Issue.3
, pp. 281-286
-
-
Schwarz, H.1
-
29
-
-
40549112657
-
CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice
-
Olofsson PS, Soderstrom LA, Wagsater D, et al. CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice. Circulation. 2008;117(10):1292-1301.
-
(2008)
Circulation
, vol.117
, Issue.10
, pp. 1292-1301
-
-
Olofsson, P.S.1
Soderstrom, L.A.2
Wagsater, D.3
|