Predominance of NK1.1+TCRαβ+ or DX5+TCRαβ+ T cells in mice conditioned with fractionated lymphoid irradiation protects against graft-versus, host disease: "Natural suppressor" cells

Journal of Immunology

Volumn 167, Issue 4, 2001, Pages 2087-2096

  Lan, F ^a   Zeng, D ^a   Higuchi, M ^a   Huie, P ^a   Higgins, J P ^a   Strober, S ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GANGLIOTETRAOSYLCERAMIDE; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN; T LYMPHOCYTE ANTIBODY;

ALLOGENIC BONE MARROW TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD TRANSFUSION; CHIMERA; CONTROLLED STUDY; CYTOKINE RELEASE; GRAFT VERSUS HOST REACTION; HLA MATCHING; LYMPH NODE IRRADIATION; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUPPRESSOR CELL; T LYMPHOCYTE SUBPOPULATION; TREATMENT PLANNING; WHOLE BODY RADIATION;

EID: 0035881968     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.4.2087     Document Type: Article

References (32)

1. Engraftment of allogeneic hematopoietic progenitor cells with purine analog-containing chemotherapy: Harnessing graft-versus-leukemia without myeloblative therapy
2. Transplant-lite: Induction of graft versus malignancy using fludarabine-based nonablative chemotherapy and allogeneic blood progenitor-cell transplantation as treatment of malignant and nonmalignant hematologic diseases
3. Non-myeloblative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases
4. Mixed chimerism preclinical studies and clinical applications
5. Engraftment kinetics after non-myeloablative allogeneic peripheral blood stem cell transplantation: Full donor T-cell chimerism precedes alloimmune responses
6. Mixed lympohaemopoietic chimerism and graft-versus-lymphoma effects after non-myeloablative therapy and HLA-mismatched bone-marrow transplantation
7. Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts
8. T cell depletion of HLA-identical allogeneic marrow grafts
9. Prevention of graft-versus-host disease by ex vivo T cell depletion: Reduction in graft failure with augmented total body irradiation
10. T cell depletion for GVHD prevention in humans
11. Treatment of high-risk acute leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype
12. Prevention of graft versus host disease by inactivation of host antigen-presenting cells
13. Transplantation of allogeneic bone marrow without graft vs. host disease using total lymphoid irradiation
14. Engraftment of allogeneic bone marrow without graft vs. host disease in mongrel dogs using total lymphoid irradiation
15. Human bone marrow lymphocytes. I. Distribution of lymphocyte subpopulations in the bone marrow of normal individuals
16. Thymus-dependent lymphocytes in human bone marrow
17. + T cells reciprocally regulate acute graft versus host disease
18. Mouse CDI-specific NK1 T cells: Development, specificity, and function
19. + T cells by CDI-expressing cortical thymocytes
20. Rapid death and regeneration of NK T cells in anti-CD3ε- or IL-12-treated mice: A major role for bone marrow in NK T cell homeostasis
21. Tissue-specific segregation of CDld-dependent and CDld-independent NK T cells
22. + cells play a protective role in the occurrence of graft-versus-host disease in mice
23. Genomic structure and strain-specific expression of the natural killer cell receptor NKR-P1
24. Alloantigen priming after total lymphoid irradiation alters alloimmune cytokine responses
25. Evidence for mouse Th1-and Th2-like helper T cells in vivo. Selective reduction of Th1-like cells after total lymphoid irradiation
26. Suppression of the mixed leukocyte response and of graft-versus-host disease by spleen cells following total lymphoid irradiation (TLI)
27. Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: Exploring obscure relationships
28. Total lymphoid irradiation leads to transient depletion of the mouse thymic medullar and persistent abnormalities among medullary stromal cells
29. Allogeneic bone marrow cells that facilitate complete chimerism and eliminate tumor cells express both CD8 and T-cell receptor-αβ
30. - lymphoid engraftment
31. + donor T cells fail to induce experimental acute graft-versus-host disease
32. + cell lines