Unraveling the intracellular efficacy of dextran-histidine polycation as an efficient nonviral gene delivery system

Molecular Pharmaceutics

Volumn 9, Issue 1, 2012, Pages 121-134

  Thomas, Jane Joy ^a   Rekha, M R ^a   Sharma, Chandra P ^a  

^a SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

Author keywords

dextran histidine; gene delivery; histone; intracellular trafficking; p53; vector unpacking

Indexed keywords

DEXTRAN; HISTIDINE; NUCLEIC ACID; POLYCATION;

ANIMAL CELL; ARTICLE; CYTOTOXICITY; DRUG EFFICACY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; INTERNALIZATION; INTRACELLULAR TRANSPORT; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; ZETA POTENTIAL;

ANIMALS; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; DEXTRANS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOCYTOSIS; GENE TRANSFER TECHNIQUES; GENES, P53; HEP G2 CELLS; HEPARIN; HISTIDINE; HUMANS; NANOSTRUCTURES; NEOPLASMS; PHYSICOCHEMICAL PHENOMENA; PLASMIDS; POLYAMINES; RATS;

EID: 84855441518     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200485b     Document Type: Article

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