Nanopolymeric micelle effect on the transdermal permeability, the bioavailability and gene expression of plasmid

Molecular Pharmaceutics

Volumn 9, Issue 1, 2012, Pages 111-120

  Tong, Yaw Chong ^a   Yu, Ting Yu ^a   Chang, Shwu Fen ^b   Liaw, Jiahorng ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

nanocarrier; polymeric micelles; transdermal permeability

Indexed keywords

BETA GALACTOSIDASE; MACROGOL; NANOCARRIER; POLY(PROPYLENE OXIDE); POLYMER; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; ATOMIC FORCE MICROSCOPY; BIOAVAILABILITY; BRAIN; CYTOMEGALOVIRUS; DRUG HALF LIFE; ENZYME ACTIVITY; GENE EXPRESSION; HALF LIFE TIME; LIGHT SCATTERING; MALE; MICELLE; MOUSE; NONHUMAN; PARTICLE SIZE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SKIN; SKIN PERMEABILITY; SPINAL CORD; SPLEEN; STOMACH; TESTIS; TRANSGENE; ZETA POTENTIAL;

ADMINISTRATION, CUTANEOUS; ANIMALS; BIOLOGICAL AVAILABILITY; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; HALF-LIFE; MALE; MICE; MICE, NUDE; MICELLES; NANOSTRUCTURES; PHYSICOCHEMICAL PHENOMENA; PLASMIDS; POLYETHYLENE GLYCOLS; PROPYLENE GLYCOLS; RECOMBINANT PROTEINS; SKIN; SKIN ABSORPTION; SPECIFIC PATHOGEN-FREE ORGANISMS; TISSUE DISTRIBUTION; TRANSGENES;

EID: 84855437923     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200342h     Document Type: Article

References (53)

1. Alexander, M. Y.; Akhurst, R. J. Liposome-mediated gene transfer and expression via the skin Hum. Mol. Genet. 1995, 4, 2279-2285
2. Li, L.; Hoffman, R. M. The feasibility of targeted selective gene therapy of the hair follicle Nat. Med. 1995, 1, 705-706
3. Raghavachari, N.; Fahl, W. E. Targeted gene delivery to skin cells in vivo: a comparative study of liposomes and polymers as delivery vehicles J. Pharm. Sci. 2002, 91, 615-622 (Pubitemid 34639624)
4. Ciernik, I. F.; Krayenbuhl, B. H.; Carbone, D. P. Puncture-mediated gene transfer to the skin Hum. Gene Ther. 1996, 7, 893-899 (Pubitemid 26169654)
5. Williams, R. S.; Johnston, S. A.; Riedy, M.; DeVit, M. J.; McElligott, S. G.; Sanford, J. C. Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles Proc. Natl. Acad. Sci. U.S.A. 1991, 88, 2726-2730 (Pubitemid 21916491)
6. Zhang, L.; Li, L.; Hoffman, G. A.; Hoffman, R. M. Depth-targeted efficient gene delivery and expression in the skin by pulsed electric field: an approach to gene therapy of skin aging and other diseases Biochem. Biophys. Res. Commun. 1996, 220, 633-636 (Pubitemid 26198563)
7. Udvardi, A.; Kufferath, I.; Grutsch, H.; Zatloukal, K.; Volc-Platzer, B. Uptake of exogenous DNA via the skin J. Mol. Med. 1999, 77, 744-750
8. Kang, M. J.; Kim, C. K.; Kim, M. Y.; Hwang, T. S.; Kang, S. Y.; Kim, W. K.; Ko, J. J.; Oh, Y. K. Skin permeation, biodistribution, and expression of topically applied plasmid DNA J. Gene Med. 2004, 6, 1238-1246 (Pubitemid 40228135)
9. Dokka, S.; Cooper, S. R.; Kelly, S.; Hardee, G. E.; Karras, L. G. Dermal delivery of topically applied oligonucleotides via follicular transport in mouse skin J. Invest. Dermatol. 2005, 123, 971-975 (Pubitemid 40629098)
10. Domashenko, A.; Gupta, S.; Cotsarelis, G. Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex Nat. Biotechnol. 2000, 18, 420-423 (Pubitemid 30217530)
11. Hadgraft, J. Modulation of the barrier function of the skin Skin Pharmacol. Appl. Skin Physiol. 2001, 14 (Suppl. 1) 72-81 (Pubitemid 34299167)
12. Li, L.; Hoffman, R. M. Topical liposome delivery of molecules to hair follicles in mice J. Dermatol. Sci. 1997, 14, 101-108 (Pubitemid 27107145)
13. Foldvari, M.; Badae, I.; Wettig, S.; Baboolal, D.; Kumar, P.; Creagh, A. L.; Haynes, C. A. Topical delivery of interferon alpha by biphasic vesicles: evidence for a novel nanopathway across the stratum corneum Mol. Pharmaceutics 2010, 7, 751-762
14. Prokop, A.; Kozlov, E.; Moore, W.; Davidson, J. M. Maximizing the in vivo efficiency of gene transfer by means of nonviral polymeric gene delivery vehicles J. Pharm. Sci. 2002, 91, 67-76 (Pubitemid 34074467)
15. Raghavan, S. L.; Kiepfer, B.; Davis, A. F.; Kazarian, S. G.; Hadgraft, J. Membrane transport of hydrocorticone acetate from supersaturated solutions; the role of polymers Int. J. Pharm. 2001, 221, 95-105 (Pubitemid 32524039)
16. Takahashi, A.; Suzuki, S.; Kawasaki, N.; Kubo, W.; Miyazaki, S.; Loebenberg, R.; Bachynsky, J.; Attwood, D. Percutaneous absorption of non-steroidal anti-inflammatory drugs from in situ gelling xyloglucan formulations in rats Int. J. Pharm. 2002, 246, 179-186 (Pubitemid 35247990)
17. Yalin, M.; Oner, F.; Oner, L.; Hincal, A. A. Preparation and properties of a stable intravenous lorazepam emulsion J. Clin. Pharm. Ther. 1997, 22, 39-44 (Pubitemid 27362101)
18. Kabanov, A. V.; Batrakova, E. V.; Alakhov, V. Y. Pluronic block copolymers as novel polymer therapeutics for drug and gene delivery J. Controlled Release 2002, 82, 189-212 (Pubitemid 34880178)
19. Batrakova, E. V.; Li, S.; Miller, D. W.; Kabanov, A. V. Pluronic P85 increases permeability of a broad spectrum of drugs in polarized BBMEC and Caco-2 cell monolayers Pharm. Res. 1999, 16, 1366-1372 (Pubitemid 29449372)
20. Thuret, G.; Manissolle, C.; Campos-Guyotat, L.; Guyotat, D.; Gain, P. Animal compound-free medium and poloxamer for human corneal organ culture and dewelling Invest. Ophthalmol. Vis. Sci. 2005, 46, 816-822 (Pubitemid 41321017)
21. L via eye drop reduced corneal apoptosis following epithelial debridement J. Controlled Release 2010, 147, 76-83
22. Tong, Y. C.; Chang, S. F.; Liu, C. Y.; Kao, W. W.-Y.; Huang, C. H.; Liaw, J. Eye drop delivery of nano-polymeric micelle formulated genes with cornea-specific promoters J. Gene Med. 2007, 9, 956-966 (Pubitemid 350104410)
23. Chen, C. L.; Chang, S. F.; Lee, D.; Yang, L. Y.; Lee, Y. H.; Hsu, C. Y.; Lin, S. J.; Liaw, J. Bioavailability effect of methylprednisolone by polymeric micelle Pharm. Res. 2008, 25, 39-47
24. Liaw, J.; Lin, Y. C. Evaluation of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) gels as a release vehicle for percutaneous fentanyl J. Controlled Release 2000, 68, 273-282 (Pubitemid 30488904)
25. Kwon, S. H.; Kim, S. Y.; Ha, K. W.; Kang, M. J.; Huh, J. S.; Im, T. J.; Kim, Y. M.; Park, Y. M.; Kang, K. H.; Lee, S.; Chang, J. Y.; Lee, J.; Choi, Y. W. Pharmaceutical evaluation of genistein-loaded Pluronic micelles for oral delivery Arch. Pharmacal Res. 2007, 30, 1138-1143
26. Chang, S. F.; Chang, H. Y.; Tong, Y. C.; Chen, S. H.; Hsaio, F. C.; Lu, S. C.; Liaw, J. Nonionic polymeric micelles for oral gene delivery in vivo Hum. Gene Ther. 2004, 15, 481-493 (Pubitemid 38639619)
27. MacGregor, G. R.; Caskey, C. T. Construction of plasmids that express E. coli β-galactosidase in mammalian cells Nucleic Acids Res. 1989, 17, 2365-2369
28. Liaw, J.; Aoyagi, T.; Kataoka, K.; Sakurai, Y.; Sakurai, Y.; Okano, T. Permeation of PEO-PBLA-FITC polymeric micelles in aortic endothelial cells Pharm. Res. 1999, 16, 213-220 (Pubitemid 29135124)
29. Nesti, E.; Everill, B.; Morielli, A. D. Endocytosis as a mechanism for tyrosine kinase-dependent suppression of a voltage-gated potassium channel Mol. Biol. Cell 2004, 15, 4073-4088 (Pubitemid 39122013)
30. Oka, J. A.; Christensen, M. D.; Weigel, P. H. Hyperosmolarity inhibits galactosyl receptor-mediated but not fluid phase endocytosis in isolated rat hepatocytes J. Biol. Chem. 1989, 264, 12016-12024 (Pubitemid 19185377)
31. Al-Amoudi, A.; Dobochet, J.; Norlén, L. Nanostructure of the epidermis extracellular space as observed by cryo-electron microscopy of vitreous sections of human skin J. Invest. Dermatol. 2005, 124, 764-777 (Pubitemid 40489504)
32. Ryman-Rasmussen, J. P.; Riviere, J. E.; Monteiro-Riviere, N. A. Penetration of intact skin by quantum dots with diverse physicochemical properties Toxicol. Sci. 2006, 91, 159-165
33. Shim, J.; Seok, K. H.; Park, W. S.; Han, S. H.; Kim, J.; Chang, I. S. Transdermal delivery of minoxidil with block copolymer nanoparticles J. Controlled Release 2004, 97, 477-484 (Pubitemid 38802949)
34. Lemieux, P.; Guérin, N.; Paradis, G.; Proulx, R.; Chistyakova, L.; Kabanov, A.; Alakhov, V. Acombination of poloxamers increases gene expression of plasmid DNA in skeletal muscle Gene Ther. 2000, 7, 986-911
35. Alimi-Guez, D.; Leborgne, C.; Pembouong, G.; Van Wittenberghe, L.; Mignet, N.; Scherman, D.; Kichler, A. Evaluation of the muscle gene transfer activity of a series of amphiphilic triblock copolymers J. Gene Med. 2009, 11, 1114-1124
36. Huang, C. Y.; Ma, S. S.; Lee, S.; Radhakrishnan, R.; Braun, C. S.; Choosakoonkriang, S.; Wiethoff, C. M.; Lobo, B. A.; Middaugh, C. R. Enhancements in gene expression by the choice of plasmid DNA formulations containing neutral polymeric excipients J. Pharm. Sci. 2002, 91, 1371-1381 (Pubitemid 34651199)
37. Cevc, G.; Gebauer, D.; Stieber, J.; Schätzlein, A.; Blume, G. Ultraflexible vesicles, Transfersomes, have an extremely low pore penetration resistance and transport therapeutic amounts of insulin across the intact mammalian skin Biochim. Biophys. Acta 1998, 1368, 201-215 (Pubitemid 28031874)
38. Wachter, C.; Vierl, U.; Cevc, G. Adaptability and elasticity of the mixed lipid bilayers vesicles containing non-ionic surfactant designed for targeted drug delivery across the skin J. Drug Targeting 2008, 16, 611-625
39. Hiruta, Y.; Hattori, Y.; Kawano, K.; Obata, Y.; Maitani, Y. Novel ultra-deformable vesicles entrapped with bleomycin and enhanced to penetrate rat skin J. Controlled Release 2006, 113, 146-154 (Pubitemid 43928150)
40. Ryman-Rasmussen, J. P.; Riviere, J. E.; Monteiro-Riviere, N. A. Variables influencing interactions of untargeted quantum dot nanoparticles with skin cells and identification of biochemical modulators Nano Lett. 2007, 7, 1344-1348 (Pubitemid 46834420)
41. Zhang, L. W.; Monteiro-Riviere, N. A. Mechanisms of quantum dot nanoparticle cellular uptake Toxicol. Sci. 2009, 110, 138-155
42. Owens, D. E., III; Peppas, N. A. Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles Int. J. Pharm. 2006, 307, 93-102 (Pubitemid 41773257)
43. Kataoka, K.; Kwon, G. S.; Yokoyama, M.; Okano, T.; Sakurai, Y. Block copolymer micelles as vehicles for drug delivery J. Controlled Release 1993, 24, 119-132 (Pubitemid 23161325)
44. Tan, J. S.; Butterfield, D. E.; Voycheck, C. L.; Caldwell, K. D.; Li, J. T. Surface modification of nanoparticles by PEO/PPO block copolymers to minimize interactions with blood components and prolong blood circulation in rats Biomaterials 1993, 14, 823-833 (Pubitemid 23272148)
45. Gaur, U.; Sahoo, S. K.; De, T. K.; Ghosh, P. C.; Maitra, A.; Ghosh, P. K. Biodistribution of fluoresceinated dextran using novel nanoparticles evading reticuloendothelial system Int. J. Pharm. 2000, 20, 1-10 (Pubitemid 30466224)
46. Batrakova, E. V.; Li, S.; Vinogradov, S. V.; Alakhov, V. Y.; Miller, D. W.; Kabanov, A. V. Mechanism of Pluronic effect on P-glycoprotein efflux system in blood-brain barrier: contributions of energy depletion and membrane J. Pharmacol. Exp. Ther. 2001, 299, 483-493 (Pubitemid 32979659)
47. Sonavane, G.; Tomoda, K.; Makino, K. Biodistribution of colloidal gold nanoparticles after intravenous administration: effect of particle size Colloids Surf., B 2008, 66, 274-280
48. Batrakova, E. V.; Li, S.; Li, Y.; Alakhov, V. Y.; Elmquist, W. F.; Kabanov, A. V. Distribution kinetics of a micelle-forming block copolymer Pluronic P85 J. Controlled Release 2004, 100, 389-397 (Pubitemid 39572919)
49. Wang, Y.; Li, Y.; Zhang, L.; Fang, X. Pharmacokinetics and biodistribution of paclitaxel-loaded Pluronic P105 polymeric micelles Arch. Pharm. Res. 2008, 31, 530-538
50. Han, L. M.; Guo, J.; Zhang, L. J.; Wang, Q. S.; Fang, X. L. Pharmacokinetics and biodistribution of polymeric micelles of paclitaxel with Pluronic P123 Acta. Pharmacol. Sin. 2006, 27, 747-753 (Pubitemid 43943925)
51. Thierry, A. R.; Lunardi-Iskandar, Y.; Bryant, J. L.; Rabinovich, P.; Gallo, R. C.; Mahan, L. C. Systemic gene therapy: biodistribution and long-term expression of a transgene in mice Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 9742-9746
52. Osaka, G.; Carey, K.; Cuthbertson, A.; Godowski, P.; Patapoff, T.; Ryan, A.; Gadek, T.; Mordenti, J. Pharmacokinetics, tissue distribution, and expression efficiency of plasmid [33P]DNA following intravenous administration of DNA/cationic lipid complexes in mice: use of a novel radionuclide approach J. Pharm. Sci. 1996, 85, 612-618
53. Liu, F.; Qi, H.; Huang, L.; Liu, D. Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration Gene Ther. 1997, 4, 517-523 (Pubitemid 27352948)