Topical liposome delivery of molecules to hair follicles in mice

Journal of Dermatological Science

Volumn 14, Issue 2, 1997, Pages 101-108

  Li, Lingna ^a   Hoffman, Robert M ^a  

^a ANTICANCER INC   (United States)

Author keywords

hair disease; hair follicle; liposome delivery

Indexed keywords

CALCEIN; LIPOSOME; MELANIN; PHOSPHATIDYLCHOLINE;

ALOPECIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG DELIVERY SYSTEM; HAIR ANALYSIS; HAIR DISEASE; HAIR FOLLICLE; HYPOPIGMENTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPECTROFLUOROMETRY; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EVALUATION STUDIES; FLUORESCEINS; FLUORESCENT DYES; HAIR DISEASES; HAIR FOLLICLE; LIPOSOMES; MELANINS; MICE; SPECTROMETRY, FLUORESCENCE;

EID: 0031081007     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-1811(96)00557-9     Document Type: Article

References (12)

1. [1] Leighton J: A sponge matrix method for tissue culture. J Natl Cancer Inst 12: 545-561, 1951.
2. [2] Li L, Margolis LB, Paus R, Hoffman RB: Hair shaft elongation, follicle growth, and spontaneous regression in long-term, gelatin sponge-gel-supported histoculture of human scalp skin. Proc Natl Acad Sci USA 89: 8764-8768, 1992.
3. [3] Li L, Lishko VK, Hoffman RM: Liposomes can specifically target entrapped melanin to hair follicles in histocultured skin. In Vitro Cell Dev Biol 29 A: 192-194, 1993.
4. [4] Li L, Lishko VK, Hoffman RM: Liposome targeting of high molecular weight DNA to the hair follicles of histocultured skin: A model for gene therapy of the hair-growth processes. In Vitro Cell Dev Biol 29A: 258-260, 1993.
5. [5] Li L, Margolis LB, Lishko VK, Hoffman RM: Product-delivering liposomes specifically target hair follicles in histocultured intact skin. In Vitro Cell Dev Biol 28A: 679-681, 1992.
6. [6] Li L, Hoffman RM: Model of selective gene therapy of hair growth: liposome targeting of the active Lac-Z gene to hair follicles of histocultured skin. In Vitro Cell Dev Biol 31A: 11-13, 1995
7. [7] Li L, Hoffman RM: The feasibility of targeted selective gene therapy of the hair follicle. Nature Med 1: 705-706, 1995.
8. [8] Yarosh D, Atlas LG, Yee V, Oberyszyn A, Kibitel JT, Mitchell D, Rosenstein R, Spinowitz A, Citron M: Pyrimidine dimer removal enhanced by DNA repair liposomes reduces the incidence of UV skin cancer in mice. Cancer Res 52: 4227-4231, 1992.
9. [9] Yarosh D, Bucana C, Cox P, Alas L, Kibitel J, Kripke M: Localization of liposomes containing a DNA repair enzyme in murine skin. J Invest Dermatol 103: 461-468. 1994.
10. [10] Lieb LM, Ramachandra C, Egbaria K, Weiner N: Topical delivery enhancement with multilamellar liposomes into pilosebaceous units: I. In vitro evaluation using fluorescent techniques with the hamster ear model. J Invest Dermatol 99: 108-113, 1992.
11. [11] Balsari AL, Morell D, Menard S, Veronesi U, Colnadhi MI: Protection against doxorubicin-induced alopecia in rats by liposome-entrapped monoclonal antibodies. FASEB J 8: 226-230, 1994.
12. [12] Prausnitz MR, Bose VG, Langer R, Weaver JC: Electroporation of mammalian skin: A mechanism to enhance transdermal drug delivery. Proc Natl Acad Sci USA 90: 10504-10508, 1993.