Anti-diabetic effects of walnut oil on alloxan-induced diabetic rats

African Journal of Pharmacy and Pharmacology

Volumn 5, Issue 24, 2011, Pages 2655-2661

  Rahimi, Parivash ^a   Kabiri, Najmeh ^a   Asgary, Sedigheh ^b   Setorki, Mahbubeh ^c  

^a UNIVERSITY OF ISFAHAN   (Iran)

^b ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Alloxan; Diabetes mellitus type I; Rat; Walnut

Indexed keywords

ANTIDIABETIC AGENT; CHOLESTEROL; GLIBENCLAMIDE; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; JUGLANS REGIA OIL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; DRUG MECHANISM; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; INSULIN BLOOD LEVEL; MALE; NONHUMAN; PANCREAS ISLET; RAT; TRIACYLGLYCEROL BLOOD LEVEL; VALIDITY;

EID: 84855423827     PISSN: None     EISSN: 19960816     Source Type: Journal    
DOI: 10.5897/AJPP11.480     Document Type: Article

References (63)

1. Agrawal RP, Kochar DK, Sahani MS, Tuteja FC, Ghorui SK (2004). Hypoglycemic activity of camel milk in streptozotocin induced diabetic rats. Int. J. Diab. Dev. Countries, 24: 47-49.
2. Al-Numair KS, Chandramohan G, Alsaif MA (2011). Effect of camel milk on collagen abnormalities in streptozotocin-diabetic rats. Afr. J. Pharm. Pharmacol., 5(2): 238-243.
3. Amaral JS, Casal S, Pereira JA, Seabra RM, Olivera BPP (2003). Determination of Sterol and Fatty Acid Compositions, Oxidative Stability, and Nutritional Value of Six Walnut (Juglans regia L.) Cultivars Grown in Portugal. J. Agric. Food Chem., 51
4. Bedoya FJ, Solano F, Lucas M (1996). N-monomethyl-arginine and nicotinamide prevent streptozotocin-induced double strand DNA break formation in pancreatic rat islets. Experientia, 52: 344-347.
5. Bolaffi JL, Nagamatsu S, Harris J, Grodsky GM (1987). Protection by thymidine, an inhibitor of polyadenosine diphosphate ribosylation, of streptozotocin inhibition of insulin secretion. Endocrinology, 120: 2117-2122.
6. Bucher HC, Hengstler P, Schindler C, Meier G (2002). N-3 polyunsaturated fatty acids in coronary heart disease: a metaanalysis of randomized controlled trials. Am. J. Med., 112: 298 304.
7. Centers for Disease Control and Prevention. Preventing diabetes and its complications [article online], 2008. Available from http://www.cdc.gov/nccdphp/publications/factsheets/Prevention/diabe tes.htm. Accessed 22 July, 2009.
8. Chew BP, Wong TS, Shultz TD, Magnuson NS (1997). Effects of conjugated dienoic derivatives of linoleic acid and beta-carotene in modulating lymphocyte and macrophage function. Anticancer Res., 17: 1099-1106.
9. Das UN (2001). Nutritional factors in the pathobiology of human essential hypertension. 17: 337-346.
10. Dhandapani S, Subramanian VR, Rajagopal S, Namasivayam N (2002). Hypolipidemic effect of Cuminum cyminum L. on alloxan- induced diabetic rats. Pharmacol. Res., 46: 251-255.
11. Dunger A, Cunningham JM, Delaney CA, Lowe JE, Green MH, Bone AJ, Green IC.)1996). Tumor necrosis factor-alpha and interferongamma inhibit insulin secretion and cause DNA damage in unweaned rat islets: extent of nitric oxide involvement. Diabetes 45: 183-189.
12. Duke JA (1989). Handbook of Nuts. CRC Press, London.
13. Dhandapani S, Subramanian VR, Rajagopal S, Namasivayam N (2002). Hypolipidemic effect of Cuminum cyminum L. on alloxan- induced diabetic rats. Pharmacol. Res., 46: 251-255.
14. El-demerdash FM, Yousef M I, Abou El-Naga NI (2005). Biochemical study on the hypoglycemic effects of onion and garlic in alloxan - induced diabetic rats. Food Chem. Toxicol., 43: 57-63.
15. Feldman EB (2002). The scientific evidence for a beneficial health relationship between walnuts and coronary heart disease. J. Nutr., 132: 1062S-1101S.
16. Flachs P, Mohamed-Ali V, Horakova O, Rossmeisl M, Hosseinzadeh- Attar MJ, Hensler M, Ruzickova J, Kopecky J.(2006). Polyunsaturated fatty acids of marine origin induce adiponectin in mice fed a high-fat diet. Diabetologia. 49:394-7.
17. Fr ojd o S, Durand C, Pirola L (2008). Metabolic effects of resveratrol in mammals - a link between improved insulin action and aging. Curr. Aging Sci., 1: 145-151.
18. Fukuda T, Ito H, Yoshida T (2003). Antioxidative polyphenols from walnuts (Juglans regia L.). Phytochemistry, 63: 795-801
19. Ha YL, Storkson J, Pariza MW (1990). Inhibition of benzo(a)pyrene induced mouse forestomach neoplasia by conjugated dienoic derivatives of linoleic acid. Cancer Res., 50:1097
20. Harper CR, Jacobson TA (2001). The fats of life: The role of Omega-3 Fatty Acids in the Prevention of Coronary Heart Disease. Arch. Intern. Med., 161: 2185 2192.
21. Haffner SM, Hazuda HP, Mitchell BD, Patterson JK, Stern MP (1991). Increased incidence of type II diabetes in Mexican Americans. Diabetes Care, 14: 102-108.
22. Hemmerle H, Burger HJ, Below P, Schubert G, Ripple R, Schindler PW, Paulus E, Herling AW (1997). Chlorogenic acid and synthetic chlorogenic acid derivatives: novel inhibitors of hepatic glucose-6- phosphate translocase. J. Med. Chem., 40: 137-145.
23. Higa M, Zhou YT, Ravazzola M, Baetens D, Orci L, Unger RH. (1999). Troglitazone prevents mitochondrial alterations, beta cell destruction, and diabetes in obese prediabetic rats. Proc. Natl. Acad. Sci. USA. 96: 11513.
24. Houseknecht KL, Vanden Heuvel JP, Moya-Camarena SY, Portocarrero CP, Peck LW, Nickel KP, Belury MA (1998). Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat. Biochem. Biophys. Res. Commun., 1998; 244:678.
25. Houee C, Gardes M, Pucheault J, Ferradini C (1981). Radical chemistry of alloxan-dialuric acid: role of the superoxide radical, Bull. Eur. Physiopathol. Respir., 17: 43-48.
26. Jelodar G, Maleki M, Motadayen MH, Sirus S (2005). Effect of fenugreek, onion and garlic on blood glucose and histopathology of pancreas of alloxan-induced diabetic rats. Indian J. Med. Sci., 59: 64-69.
27. Jimenez-Gomez Y, Lopez-Miranda J, Blanco-Colio LM, Marin C, Perez- Martinez P, Ruano J, Paniagua JA, Rodriguez F, Egido J, Perez- Jimerez F (2008). Olive oil and walnut breakfasts reduce the postprandial inflammatory response in mononuclear cells compared with a butter breakfast in healthy men. Atherosclerosis, 204:e70-76.
28. Kim HK, Kim MJ, Cho HY, Kim EK, Shin DH (2006). Antioxidative and anti-diabetic effects of amaranth (Amaranthus esculantus) in streptozotocin-induced diabetic rats. Cell Biochem. Funct., 24: 195-199.
29. Knowler WC, Pettitt DJ, Savage PJ, Bennett PH (1981). Diabetes incidence in Pima Indians: contribution of obesity and parental diabetes. Am. J. Epidemiol., 113: 144-156.
30. King H, Zimmet P, Raper LR, Balkau B (1984). The natural history of impaired glucose tolerance in the Micronesian population of Nauru: a six year follow-up study. Diabetologia, 26: 39-43.
31. Kim NN (2009). Sex steroid hormones in diabetes-induced sexual dysfunction: focus on the female gender. J. Sex Med., 6(3): 239-246.
32. Kulkarni JS, Metha AA, Santani DD, Goyal RK (2002). Effects of chronic treatment with cromakalim and glibenclamide in alloxan-induced diabetic rats. Pharmacol. Res., 46: 101-105.
33. Kumar MV, Vanegas SM, Patel N, Aitken JD, Ziegler TR, Ganji V (2011). Fish oil rich diet in comparison to saturated fat rich diet offered protection against lipopolysaccharide-induced inflammation and insulin resistance in mice. Nutrition & Metabolism, 8: 16, 11-30.
34. Kwon O, Esk P, Chen S, Corpe CP, Lee JH, Kruhlak M, Levine M (2007). Inhibition of the intestinal glucose transporter GLUT2 by flavonoids. FASEB J., 21: 366-377.
35. Laight DW, Kaw AV, Carrier MJ, Anggard EE (1998). Interaction between superoxide anion and nitric oxide in the regulation of vascular endothelial function, Br. J. Pharmacol., 124: 238-244.
36. Lillioja S, Mott DM, Spraul M, Ferraro R, Foley JE, Ravussin E, Knowler WC, Bennett PH, Bogardus C(1993). Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus: prospective studies of Pima Indians. N. Engl. J. Med., p. 329.
37. Li WL, Zheng HC, Bukuru J, De Kimpe N (2004). Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. J. Ethnopharmacol., 92: 1-21.
38. Mohamed A, Mehaia MA, Hablas KM, Abdel-Rahman SA (1995). El- Mougy Milk composition of Majaheim, Wadah and Hamra camels in Saudi Arabia. Food Chem., 52: 115-122.
39. Mohan IK, Das UN (2001). Prevention of chemically induced diabetes mellitus in experimental animals by polyunsaturated fatty acids. Nutrition, 17: 126-151.
40. May Y, Njike VY, Mille TJ, Dutta S, Doughty K, Treu J, Katz DL (2010). Effects of Walnut Consumption on Endothelial Function in Type 2 Diabetic Subjects Diabetes Care, 33: 227-232.
41. Micallef MA, Garg ML (2009). Anti-inflammatory and cardioprotective effects of n-3 polyunsaturated fatty acids and plant sterols in hyperlipidemic individuals. Atherosclerosis, 204: 476-482.
42. Martínez ML, Labuckas DO, Lamarque AL, Maestri DM (2010). Walnut (Juglans regia L.): genetic resources, chemistry, by-products. J. Sci. Food Agric., 90: 12, 1959-1967.
43. Nielsen JN (1986). Affinity purified human interleukin-1 is cytotoxic to isolated islets of Langerhans. Diabetologia, 29: 63-67.
44. Nagappa AN, Thakurdesai PA, Venkat Rao N, Singh J (2003). Antidiabetic activity of Terminalia catappa Linn fruits. J. Ethnopharmacol., 88: 45-50.
45. Nukatsuka M, Yoshimura Y, Nishida M, Kawada J (1990b). Importance of the concentration of ATP in rat. pancreatic beta cells in the mechanism of streptozotocin-induced cytotoxicity. J. Endocrinol., 127: 161-165.
46. Ouellet V, Weisnagel SJ, Marois J, Bergeron J, Julien P, Gougeon R, Tchernof A, Holub BJ, Jacques H (2008). Dietary cod protein reducesplasma C-reactive protein in insulin-resistant men and women. J. Nutr., 138: 2386-2391.
47. Perry LM (1980). Medicinal Plants of East and Southeast Asia: Attributed Properties and Uses. MIT Press, Cambridge, MA, USA. ISBN 9780262160766.
48. Pereira JA, Oliveira I, Sousa A, Valentao P, Andrade P, Ferreira I, Ferreres F, Bento A, Seabra R, Estevinho L (2007). Walnut (Juglans regia L.) leaves: phenolic compound, antibacterial activity and antioxidant potential of different cultivars. Food Chem. Toxicol., 45(11): 2287-2295.
49. Robertson DG, DiGirolamo M, Merrill AH, Lambethll D (1988). Insulinstimulated Hexose Transport and Glucose Oxidation in Rat Adipocytes Is Inhibited by Sphingosine at a Step after Insulin Binding. J Biol. L. Chem., 269(12): 6773-6779.
50. Ragavan B, Krishnakumari S (2006). Antidiabetic effect of T. Arjuna bark extract in alloxan induced diabetic rats. Indian J. Clin. Biochem., 21: 123-128.
51. Shivananda NB, Geetha B (2005). Relationship between Sialic acid and metabolic variables in Indian type 2 diabetic patients. Lipids in Health and Disease 4: 15 doi: 10.1186/1476-511X-4-15.
52. Singh R (2001). Annual Report NRCC, Bikaner, p. 50.
53. Solar A, Colaric M, Usenik V, Stampar F (2006). Seasonal variations of selected flavonoids, phenolic acids and quinones in annual shoots of common walnut (Juglans regia L.). Plant Sci., 170: 453-461.
54. Suresh Y, Das UN (2001). Protective action of arachidonic acid against alloxan-induced cytotoxicity and diabetes mellitus, Prostaglandins Leukot. Essent. Fatty Acids, 64: 37-52.
55. Suresh Y, Das UN (2003a). Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus: effect of o-6 fatty acids. Nutrition, 19: 93-114.
56. Szkudelski T (2001). The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol. Res., 50: 536-546.
57. Szkudelski T, Szkudelska K (2011). Anti-diabetic effects of resveratrol. Ann. N.Y. Acad. Sci., 34-39.
58. Szkudelska K, Szkudelski T (2010). Resveratrol, obesity and diabetes. Eur. J. Pharmacol., 635: 1-8.
59. Suresh Y, Das UN (2006). Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxaninduced diabetes mellitus Prostaglandins. Leukotrienes and Essential Fatty Acids, 74: 199-213
60. Watkins D, Cooperstein SJ, Feil S (1979). Studies on the selectivity of alloxan for the beta cells of the islets of langerhans: effect of pH on the in vitro action of alloxan. J. Pharmacol. Exp. Ther., 208: 184-189.
61. West E, Simon OR, Morrison EY (1996). Streptozotocin alters pancreatic beta-cell responsiveness to glucose within six hours of injection into rats. West Indian Med. J., 45: 60-62.
62. Wright JR, Lefkowith JB, Schreiner G, Lacy PE (1988). Essential fatty acid deficiency prevents multiple low-dose streptozotocin-induced diabetes in CD-1 mice. Proc. Natl. Acad. Sci. USA, 85: 6137
63. Wilson GL, Patton NJ, McCord JM, Mullins DW, Mossman BT (1984). Mechanisms of streptozotocin- and alloxan-induced damage in rat B cells. Diabetologia, 27(6): 587-591.