Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus: Effect of ω-6 fatty acids

Nutrition

Volumn 19, Issue 2, 2003, Pages 93-114

  Suresh, Y ^a   Das, U N ^a  

^a EFA Sciences LLC   (United States)

Author keywords

6 fatty acids; Alloxan; Antioxidants; Diabetes mellitus; Glucose; Insulin

Indexed keywords

ALLOXAN; ARACHIDONIC ACID; DIHOMO GAMMA LINOLENIC ACID; GAMMA LINOLENIC ACID; LINOLEIC ACID; LIPOXYGENASE INHIBITOR; MONOUNSATURATED FATTY ACID; OLEIC ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; PROSTAGLANDIN SYNTHASE INHIBITOR; SATURATED FATTY ACID; STEARIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DIABETES MELLITUS; DIET SUPPLEMENTATION; DISEASE SEVERITY; IN VITRO STUDY; INSULINOMA; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ALLOXAN; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; ENZYMES; FATTY ACIDS, OMEGA-6; FATTY ACIDS, UNSATURATED; INSULINOMA; LIPIDS; MALE; PANCREAS; RATS; RATS, WISTAR;

ANIMALIA;

EID: 0037321243     PISSN: 08999007     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0899-9007(02)00856-0     Document Type: Article

References (89)

1. Nielsen J.H. Affinity purified human interleukin-1 is cytotoxic to isolated islets of Langerhans. Diabetologia. 29:1986;63.
2. Dunger A., Cunningham J.M., Delaney C.A., et al. Tumor necrosis factor-alpha and interferon-gamma inhibit insulin secretion and cause DNA damage in unweaned rat islets extent of nitric oxide involvement . Diabetes. 45:1996;183.
3. Das U.N. Inhibition of sensitized lymphocyte response to sperm antigen(s) by prostaglandins. IRCS Med Sci. 9:1981;1087.
4. Su C.G., Wen X., Bailey S.T., et al. A novel therapy for colitis utilizing PPAR-γ ligands to inhibit the epithelial inflammatory response. J Clin Invest. 104:1999;383.
5. Houseknecht K.L., Vanden Heuvel J.P., Moya-Camarena S.Y., et al. Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat. Biochem Biophys Res Commun. 244:1998;678.
6. Higa M., Zhou Y.T., Ravazzola M., et al. Troglitazone prevents mitochondrial alterations, beta cell destruction, and diabetes in obese prediabetic rats. Proc Natl Acad Sci USA. 96:1999;11513.
7. Ha Y.L., Storkson J., Pariza M.W. Inhibition of benzo(a)pyrene induced mouse forestomach neoplasia by conjugated dienoic derivatives of linoleic acid. Cancer Res. 50:1990;1097.
8. Fukuzawa M., Satoh J., Qiang X., et al. Inhibition of tumor necrosis factor-alpha with anti-diabetic agents. Diabetes Res Clin Pract. 43:1999;147.
9. Chew B.P., Wong T.S., Shultz T.D., Magnuson N.S. Effects of conjugated dienoic derivatives of linoleic acid and beta-carotene in modulating lymphocyte and macrophage function. Anticancer Res. 17:(2A):1997;1099.
10. Hayek M.G., Han S.N., Wu D., et al. Dietary conjugated linoleic acid influences the immune response of young and old C57BL/6NCr1BR mice. J Nutr. 129:1999;32.
11. Suresh Y., Das U.N. Protective action of arachidonic acid against alloxan-induced cytotoxicity and diabetes mellitus. Prostaglandins Leukot Essent Fatty Acids. 64:2001;37.
12. Mohan I.K., Das U.N. Prevention of chemically induced diabetes mellitus in experimental animals by polyunsaturated fatty acids. Nutrition. 17:2001;126.
13. Mossman T. Rapid colorimetric assay for cellular growth and survival application to proliferation and cytotoxicity assays. J Immunol Methods. 65:1983;55.
14. Hodgson V.J., Walker G.M., Button A. A rapid colorimetric assay of killer activity in yeast. FEMS Microbiol Lett. 120:1994;201.
15. Cunnane S.C., Keeling P.W., Thompson R.P., Crawford M.A. Linoleic acid and arachidonic acid metabolism in human peripheral blood leucocytes comparison with the rat . Br J Nutr. 51:1984;209.
16. Das U.N., Huang Y.S., Begin M.E., Ells G., Horrobin D.F. Uptake and distribution of cis-unsaturated fatty acids and their effect on free radical generation in normal and tumor cells in vitro. Free Radic Biol Med. 3:1987;9.
17. Das U.N., Begin M.E., Ells G. Fatty acid changes during the induction of differentiation of human promyelocytic leukemia (HL-60) cells by phorbolmyristate acetate. Prostaglandins Leukot Essent Fatty Acids. 46:1992;235.
18. Heikkila R.E., Winston B., Cohen G. Alloxan induced diabetes - evidence for hydroxyl radical as a cytotoxic intermediate. Biochem Pharmacol. 25:1976;1085.
19. Sambrook J., Fritsch E.F., Maniatis T. Molecular cloning a laboratory manual. 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Press, 1989:9.14
20. Mohan I.K., Das U.N. Effect of L-arginine-nitric oxide system on chemical-induced diabetes mellitus. Free Radic Biol Med. 25:1998;757.
21. Das U.N., Krishna Mohan I., Vijay Kumar K., Kumar S.G., Chandra Sekhar C. Beneficial effect of L-arginine in non-insulin dependent diabetes mellitus a potential role for nitric oxide . Med Sci Res. 21:1993;669.
22. 15 nitrite in biological fluids. Anal Biochem. 26:1982;131.
23. Bernheim S., Bernheim M.L.C., Wilbar K.M. The reaction between thiobarbituric acid and the oxidation products of certain lipids. J Biol Chem. 174:1948;257.
24. Das U.N. Tumoricidal action of cis-unsaturated fatty acids and its relationship to free radicals and lipid peroxidation. Cancer Lett. 56:1991;235.
25. Sangeetha P.S., Das U.N. Cytotoxic action of cis-unsaturated fatty acids on human cervical (HeLa) carcinoma cells in vitro. Prostaglandins Leukot Essent Fatty Acids. 53:1995;287.
26. Ravin H.A. An improved colorimetric enzymatic assay of ceruloplasmin. J Lab Clin Med. 58:1961;161.
27. Drabkin D.L., Austin J.H. Spectrophotometric studies preparation from washed blood cells, nitric oxide, haemoglobin and sulfahaemoglobin . J Biol Chem. 112:1988;51.
28. McCord J.M., Fridovich I. Superoxide dismutase. An enzyme function for erythrocuprein (hemocuprein). J Biol Chem. 244:1969;6049.
29. Aebi H. Catalase. Methods in enzymology. Vol 105:1984;121 Academic Press, New York.
30. Huang Y.S., Das U.N., Horrobin D.F. Effect of dexamethasone on the distribution of essential fatty acids in plasma and liver phospholipids. IRCS Med Sci. 14:1986;180.
31. Tomita T., Lacy P.E., Natschinsky F.M., McDaniel M.L. Effect of alloxan on insulin secretion in isolated rat islets perfused in vitro. Diabetes. 23:1974;517.
32. Borg L.A., Eide S.J., Anderson A., Hellerstrom C. Effects in vitro of alloxan on the glucose metabolism of mouse pancreatic β cells. Biochem J. 182:1979;797.
33. Ishibashi F., Sato T., Onari K., Kawata R. Alloxan inhibits glucose oxidation in the pancreatic islets. Endocrinol Jpn. 26:1979;395.
34. Heikkila R.E., Winston B., Cohen G. Alloxan induced diabetes-evidence for hydroxyl radical as a cytotoxic intermediate. Biochem Pharmacol. 25:1976;1085.
35. Malaisse W.J., Malaisse-Lagae F., Sener A., Pipeleers D.G. Determinants of the selective toxicity of alloxan to the pancreatic β cell. Proc Natl Acad Sci USA. 79:1982;927.
36. Mohan I.K., Das U.N. Effect of L-arginine-nitric oxide system on chemical-induced diabetes mellitus. Free Radic Biol Med. 25:1998;757.
37. Grankvist K., Marklund S., Sehlin J., Taljedal I.B. Superoxide dismutase, catalase and scavengers of hydroxyl radicals protect against toxic action of alloxan on pancreatic islet cells in vitro. Biochem J. 182:1979;17.
38. Gandy S.E., Buse N.G., Crouch R.K. Protective role of superoxide dismutase against diabetogenic drugs. J Clin Invest. 70:1982;650.
39. Boquist L. Factors affecting the beta cell sensitivity to alloxan in vivo. Influence of pre- and post-treatment with protective substances. Acta Endocrinol (Copenh). 88:1978;556.
40. Tibaldi J., Benjamin J., Cabbat F.S., Heikkila R.E. Protection against alloxan-induced diabetes by various derivatives relationship between protective effects and reactivity with the hydroxyl radical . J Pharmacol Exp Ther. 211:1979;415.
41. Slonim A.E., Surber M.L., Page D.L., Sharp R.A., Burr I.M. Modification of chemically-induced diabetes in rats by vitamin E supplementation minimizes and depletion enhances development of diabetes. J Clin Invest. 71:1983;1282.
42. Laight D.W., Kaw A.V., Carrier M.J., Anggard E.E. Interaction between superoxide anion and nitric oxide in the regulation of vascular endothelial function. Br J Pharmacol. 124:1998;238.
43. Das U.N. Interaction(s) between nutrients, essential fatty acids, eicosanoids, free radicals, nitric oxide, anti-oxidants and endothelium and their relationship to human essential hypertension. Med Sci Res. 28:2000;75.
44. Das U.N. Nutritional factors in the pathobiology of human essential hypertension. Nutrition. 17:2001;337.
45. Asayama K., English D., Slonim A.E., Burr F.M. Chemiluminescence as an index of drug-induced free radical production in pancreatic islets. Diabetes. 33:1984;160.
46. Grankvist K., Marklund S., Sehlin J., Taljedal I.B. Superoxide dismutase, catalase and scavengers of hydroxyl radicals protect against the toxic action of alloxan on pancreatic islet cells in vitro. Biochem J. 182:1979;17.
47. Fischer P.J., Hamburger S.A. Inhibition of alloxan action in isolated pancreatic islets by superoxide dismutase, catalase and a metal chelator. Diabetes. 29:1980;213.
48. Gandy S.E., Buse N.G., Crouch R.K. Protective role of superoxide dismutase against diabetogenetic drugs. J Clin Invest. 70:1982;650.
49. Jorns A., Tiedge M., Lenzen S., Munday R. Effect of superoxide dismutase, catalase, chelating agents, and free radical scavengers on the toxicity of alloxan to isolated pancreatic islets in vitro. Free Radic Biol Med. 26:1999;1300.
50. Sandhya L.S., Ramesh R.B. Protective mechanism of glucose against streptozotocin-induced free radical generation in pancreatic islets in vivo and in vitro. Curr Sci. 76:1999;231.
51. Hiramatsu K., Arimori S. Increased superoxide production by mononuclear cells of patients with hypertriglyceridemia and diabetes. Diabetes. 29:1980;251.
52. Mohan I.K., Das U.N. Oxidant stress, anti-oxidants and nitric oxide in non-insulin dependent diabetes mellitus. Med Sci Res. 25:1997;55.
53. Hattori Y., Kawasaki H., Abe K., Kanno M. Superoxide dismutase recovers altered endothelium-dependent relaxation in diabetic rat aorta. Am J Physiol. 261:1991;H1086.
54. Giugliano D., Ceriello A., Paolisso G. Diabetes mellitus, hypertension and cardiovascular disease which role of oxidative stress . Metabolism. 44:1995;363.
55. Das U.N., Kumar K.V., Mohan I.K. Lipid peroxides and essential fatty acids in patients with diabetes mellitus and diabetic nephropathy. J Nutr Med. 4:1994;149.
56. Corbett J.A., McDaniel M.L. Does nitric oxide mediate autoimmune destruction of beta cells? Possible therapeutic interventions in IDDM. Diabetes. 41:1992;897.
57. Kroncke K.D., Kolb-Bachofen V., Berschick B., Burkart V., Kolb H. Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation. Biochem Biophys Res Commun. 175:1991;752.
58. Kolb H., Kolb-Bachofen V. Nitric oxide a pathogenetic factor in autoimmunity . Immunol Today. 13:1992;157.
59. Fehsel K., Jalowy A., Qi S., et al. Islet cell DNA damage is a target of inflammatory attack by nitric oxide. Diabetes. 42:1993;496.
60. Jurgen R., Birgit H., Alexander B., et al. Nitric oxide toxicity in islet cells involves poly(ADP-ribose) polymerase activation and concomitant NAD depletion. Biochem Biophys Res Commun. 199:1994;1270.
61. Yamada K., Nonaka K., Hanafusa T., et al. Preventive and therapeutic effects of large-dose nicotinamide injections on diabetes associated with insulitis. An observation on nonobese diabetic (NOD) mice. Diabetes. 31:1982;749.
62. Burkart V., Wang Z.-Q., Radons J., et al. Mice lacking the poly(ADP-ribose) polymerase gene are resistant to beta-cell destruction and diabetes development induced by streptozotocin. Nat Med. 5:1999;314.
63. Das U.N. Essential fatty acids, lipid peroxidation and apoptosis. Prostaglandins Leukot Essent Fatty Acids. 61:1999;157.
64. Roza A.M., Pieper G.M., Johnson C.P., Adams M.B. Pancreatic antioxidant enzyme activity in normoglycemic diabetic prone BB rats. Pancreas. 10:1995;53.
65. Godin D.V., Wohaieb S.A., Garnett M.E., Goumeniouk A.D. Antioxidant enzyme alterations in experimental and clinical diabetes. Mol Cell Biochem. 84:1988;223.
66. Garg M.C., Ojha S., Bansal D.D. Antioxidant status of streptozotocin diabetic rats. Indian J Exp Biol. 34:1996;264.
67. Rema M., Mohan V., Bhaskar A., Shanmugasundaram K.R. Does antioxidant stress play a role in diabetic retinopathy. Indian J Ophthalmol. 43:1995;17.
68. Pottathil J.D., Huang S.W., Chandrabose K.A. Essential fatty acids in diabetes and systemic lupus erythematosus patients. Biochem Biophys Res Commun. 128:1985;803.
69. Dang A.Q., Kemp K., Faas F.H., Carter W.J. Effect of dietary fats on fatty acid composition and delta-5-desaturase in normal and diabetic rats. Lipids. 24:1989;882.
70. Mercuri O., Peluffo R.O., Brenner R.R. Depression of microsomal desaturation of linoleic to gamma-linolenic acid in the alloxan diabetic rat. Biochim Biophys Acta. 116:1966;409.
71. Tilvis R.S., Miettinen T.A. Fatty acid compositions of serum lipids, erythrocytes and platelets in insulin-dependent diabetic women. J Clin Endocrinol Metab. 61:1985;741.
72. Das U.N. Insulin resistance and hyperinsulinemia are they secondary to an alteration in the metabolism of essential fatty acids? Med Sci Res. 22:1994;243.
73. McVeigh G.E., Brennan G.M., Johnston G.D., et al. Dietary fish oil augments nitric oxide production or release in patients with type 2 diabetes mellitus. Diabetologia. 36:1993;33.
74. Venkatraman J.T., Chandrasekhar B., Kim J.D., Fernandes G. Effect of n-3 and n-6 fatty acids on the activities of expression of hepatic antioxidant enzymes in auto-immune-prone NZB× NZW mice. Lipids. 29:1994;561.
75. Mohan I.K., Das U.N. Oxidant stress, anti-oxidants and essential fatty acids in systemic lupus erythematosus. Prostaglandins Leukot Essent Fatty Acids. 56:1997;193.
76. Zawalich W.S., Diaz V.A. Interleukin-1 inhibits insulin secretion from isolated perfused rat islets. Diabetes. 35:1986;1119.
77. Mooradian A.D., Reed R.L., Meredith K.E., Scuderi P. Serum levels of tumor necrosis factor and IL-1 alpha and IL-1 beta in diabetic patients. Diabetes Care. 14:1991;63.
78. Campbell I.L., Iscaro A., Harrison L.C. IFN-gamma and tumor necrosis factor-alpha cytotoxicity of murine islets of Langerhans . J Immunol. 141:1988;2325.
79. Rabinovitch A., Suarez-Pinzon W.L., Strynadka K., Lakey J.R., Rajotte R.V. Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production. J Clin Endocrinol Metab. 81:1996;3197.
80. Endres S., Ghorbani R., Kelley V.E., et al. The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N Engl J Med. 320:1989;265.
81. Kumar S.K., Das U.N. Effect of prostaglandins and their precursors on the proliferation of human lymphocytes and their secretion of tumor necrosis factor and various interleukins. Prostaglandins Leumot Essent Fatty Acids. 50:1994;331.
82. Santoli D., Zurier R.B. Prostaglandin E precursor fatty acids inhibit human IL-2 production by a prostaglandin E-independent mechanism. J Immunol. 143:1989;1303.
83. Kumar S.K., Das U.N., Kumar K.V., et al. Effect of n-6 and n-3 fatty acids on the proliferation and secretion of TNF and IL-2 by human lymphocytes in vitro. Nutr Res. 12:1992;815.
84. Horrobin D.F., Carmichael T.A. Essential fatty acids in relation to diabetes. Horrobin D.F. Treatment of diabetic neuropathy. A new approach. 1992;21 Churchill-Livingstone, Edinburgh.
85. Stene L.C., Ulriksen J., Magnus P., Joner G. Use of cod liver oil during pregnancy associated with lower risk of type 1 diabetes in the offspring. Diabetologia. 43:2000;1093.
86. Salmeron J., Hu F.B., Manson J.E., et al. Dietary fat intake and risk of type 2 diabetes in women. Am J Clin Nutr. 73:2001;1019.
87. Das U.N. Essential fatty acids in health and disease. J Assoc Phys India. 47:1999;906.
88. Das U.N. Essential fatty acids Biology and their clinical implications . Asia Pac J Pharmacol. 6:1991;317.
89. Schrezenmeir J., Jagla A. Milk and diabetes. J Am Coll Nutr. 19:2000;176S.