Antidiabetic effect of T. arjuna bark extract in alloxan induced diabetic rats

Indian Journal of Clinical Biochemistry

Volumn 21, Issue 2, 2006, Pages 123-128

  Ragavan, B ^a   Krishnakumari, S ^b  

^a PSG COLLEGE OF ARTS AND SCIENCE   (India)

^b KONGUNADU ARTS AND SCIENCE COLLEGE   (India)

Author keywords

Aldolase; Alloxan; Antidiabetic; Gluconeogenic; Terminalia arjuna

Indexed keywords

ALCOHOL; FRUCTOSE BISPHOSPHATASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLUCOSE 6 PHOSPHATASE; GLUCOSE 6 PHOSPHATE ISOMERASE; HEXOKINASE; TERMINALIA ARJUNA EXTRACT;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BARK; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; GLUCOGENESIS; GLUCOSE BLOOD LEVEL; KIDNEY; LIVER; MALE; NONHUMAN; RAT;

TERMINALIA ARJUNA;

EID: 33751051775     PISSN: 09701915     EISSN: 09701915     Source Type: Journal    
DOI: 10.1007/BF02912926     Document Type: Article

References (35)

1. Trivedi, B., Mazumdar, J.D., Bhatt and Hemavathi, K.G. (2004) Effect of Shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats, Indian J Pharmacol. 36(6), 373-376.
2. Bailey, C. J. and Day, C. (1989) Traditional plant medicines as treatment for diabetes, Diabetes care. 12(8).
3. Rajasekaran, S., Sivagnanam, K., Narayanan, V. and Subramanian, S. (2001) Hypoglycemic and hypolipidemic effects of Aloevera on experimental rabbits. Publication of Indian Association of Biomedical Scientists. 41-45.
4. Tiwari, A.K., Gode, J.D. and Dubey, G.P. (1989) Effect of T.arjuna bark powder on serum lipids and lipoproteins in hypercholesterolemic rabbits. Indian Drugs. 26, 664.
5. Tiwari, A.K., Gode, J.D. and Dubey, G.P. (1990) Effect of T.arjuna on lipid profiles of rabbits fed hypercholesterolemic diet. Int. J. Crude Drugs Res. 28, 43-47
6. Pathak, S.R., Upadhyay, L., Singh, R.H., Dubey, G.P and Udupa, K.N. (1990) Effect of T.arjuna on autocodial and lipid profiles of rabbits. Indian drugs. 27,221-227.
7. Khanna, A.K., Chander., R. and Kapoor, N. K. (1996) T.arjuna an ayurvedic cardiotonic regulates lipid metabolism in hyperlipeaemic rats. Phyto Res. 10, 663-665
8. Shaila, H.P., Udupa, S.L., Udupa., A.L and Nair, N.S. (1997) Effect of T. arjuna on experimental hyperlipidemia in rabbits. J. Pharmacogn. 35, 1-4.
9. Ram, A., Lauria, P., Gupta, R.P., Kumar, P. and Pandsharma, V.N. (1997) Hypocholesterolemic effects of T.arjuna tree bark. J. Ethanopharmacol. 55 -165-169
10. Kusumoto, I.T., Nakabayashi, T., Kida, H., Miyashrio Hattori, M., Namba, T. and Shimotohno. (1995) Screening of various plant extracts used in ayurvedic medicine for inhibitory effects on human immunodeficiency virus-I (HIVI) protease, Phytotherapy Research. 9(3) 180.
11. Kaur, S., Grover., I.S. and Kumar, S. (2001) Anti mutagenic potential of extracts isolated from Terminalia arjuna . J. Environ Pathol Toxicol Oncol. 20, 9-14.
12. Shaila, H.P., Udupa, S.L. and Udupa, A.L. (1997a) Hypolipidemic effect of Terminalia arjuna in cholesterol fed rabbits, Fitoterapia. 68, 405-409.
13. Avinash, N., Laxman, S.M., Satwinderject, K., Iqbal, S.G., Renu, W. and Sunil, C.K. (2000) Growth suppression of human transformed cells by treatment with bark extracts from a medicinal plant Terminalia arjuna, in vitro cell, Dev. Biol-Animal. 36, 544-547.
14. Takahashi, S., Tanaka, H., Hano, V., Ito, K., Nomura, T. and Shigenobu, K. (1997) Hypotensive effect in rats of hydrophilic extract from Terminalia arjuna containing tannin, related compounds, Phytotherapy Res. 11(6), 424-427.
15. Chatterjee, S. (2000) Effect of Terminalia arjuna on abnormal platelet reactivity in hypercholesterolemic rabbits. Indian Drugs. 37(3), 135-138.
16. Kumar, D.S and Prabhakar, V.S. (1987) On the ethanomedical significance of the arjuna tree, T.arjuna (Roxb), J. Ethanopharmacol. 20, 173-190.
17. Dhawan, B.N., Patnaik, G.K., Rastogi, R.P., Singh, K.K. and Tandon, J.S. (1977) Screening of Indian plants for biological activity VI, Indian J Exp Biol. 15, 208-219.
18. Dwivedi, S., Chansouria, J.P.N., Somani, P.N. and Udupa, K.N. (1989) Effect of T. arjuna on ischaemic heart disease Alternative Medicine. 32, 115-122.
19. Ravivijayavargia, Monikakumar and Sarita Gupta. (2000) Hypoglycemic effect of aqueous extract of Enicostemma littoral Blume (Chhotachirayata) on alloxan induced diabetes mellitus in rats, Indian J Exp Biol. 38, 781-784.
20. Perfumi, M. and Tacconi, R. (1996) Antihyperglycemic effect of fresh Opuntiadillenii fruit from Tenerife (Canry islands) Indian J. Pharmacol. 34, 41.
21. Trinder, P. (1969) Glucose oxidase method, Ann. Clin. Biochem. 6, 24.
22. Branstrup, N., Krik, J.E. and Bruni, C. (1957) The hexokinase and phosphoglucoisomerase activities of aorta and pulmonary artery tissue in individuals of various ages, J. Gerontol, 12, 166 -171.
23. Horrocks, J.E., Ward, J. and Kind, J. (1963) A routine method for the determination of phosphoglucoisomerase activity in body fluid, J. Clin. Pathol. 16, 248-251.
24. King, J. (1965a) The hydrolases-acid and alkaline phosphatase In: Practical Clinical Enzymology, Van, D. Eds., Norstand company Ltd. 83-93.
25. King, J. (1965b) The dehydrogenase or oxido reductase-lactate dehydrogenase. In Practical Clinical Enzymology, Van, D. Eds., Norstand company Ltd. 83-93.
26. Gancedo, J.M. and Gancedo, C. (1971) Fructose-1, 6-diphosphatase, phosphofructokinase and glucose-6-phosphate dehydrogenase, prooc, soc. Exp. Biol. Med. 106, 607-609.
27. Prakasam, S., Sethupathy and Pugalendi, K.V. (2002) Antihyperglycaemic effect of Caseariaesculenta root extracts in streptozotocin-induced diabetic rats, Pharmazie. 57,11.
28. Bhavapriya, V. and Govidasamy, S. (2000) Biochemical studies on the hypoglycemic effect Aegle marmelos (Linn). Correa Ex. RoxB. In streptozotocin induced diabetic rats, Indian Drugs. 37(10), 474-477.
29. Vestergoard H. (1999) Studies of gene expression and activity of hexokinase, phosphofructokinase and glycogen synthetase in human skeletal muscle in states of altered insulin stimulated glucose metabolism, Dan Med Biol. 46, 13-34.
30. Sato, T., Magata K. and Koga, N. (1998) Defect of an early event of glucose metabolism in skeltal muscle of the male OLETE rat, an NIDDM model, Biochem Biophy Res Commun. 245(2), 378-381.
31. O'Doherty, R.M., Lehman, D.L., Telemaque potts, S. and Newgard, C.B. (1999) Diabetes. 48, 2022.
32. Goyal, R.K., Bhullar, S.S. and Singh, R. (1990) Plant Physiol Biochem. 28, 755.
33. Ebrahim, A.S., Babakrishnan, K. and Sakthisekaran, D. (1996) Perchloroethylene - induced alterations in glucose metabolism and their prevention by 2 deoxy-D-glucose and vitamin E in mice. J. Appl. Toxicol. 16, 339-348.
34. Arathi, G and Sachdanandam. (2003) Therapeutic effect of Semecarpus and Cardium Linn, nut milk extract on carbohydrate metabolizing and mitochondrial TCA cycle and respiratory chain enzymes in mammary carcinoma rats, J. Pharm and Pharmol. 55, 1283-1290.
35. th edition, Appleton and Lange Stanford Connecticut.