Macrophage reactivity to different polymers demonstrates particle size- and material-specific reactivity: PEEK-OPTIMA® particles versus UHMWPE particles in the submicron, micron, and 10 micron size ranges

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 100 B, Issue 2, 2012, Pages 480-492

  Hallab, Nadim James ^a,b   McAllister, Kyron ^a   Brady, Mark ^c   Jarman Smith, Marcus ^c  

^a RUSH UNIVERSITY   (United States)

^b BioEngineering Solutions Inc   (United States)

^c INVIBIO LTD   (United Kingdom)

Author keywords

fibroblasts; MG 63 osteoblasts; particles; PEEK; THP 1 macrophages; UHMWPE

Indexed keywords

10 MICRON; ARTHROPLASTIES; BIOREACTIVITY; CLINICAL PERFORMANCE; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; CYTOKINES; CYTOTOXICITY ASSAYS; HUMAN MONOCYTES; IN-VITRO ANALYSIS; ORTHOPEDIC IMPLANT; POLYMERIC PARTICLES; SUBMICRON; TIME POINTS;

CELL CULTURE; CYTOTOXICITY; DEBRIS; ELEMENTARY PARTICLES; ETHERS; FIBROBLASTS; KETONES; MACROPHAGES; POLYETHER ETHER KETONES; POLYETHYLENES; WEAR RESISTANCE;

POLYMERS;

INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; POLYETHERETHERKETONE; TUMOR NECROSIS FACTOR ALPHA; ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE; BIOMATERIAL; CYTOKINE; KETONE; MACROGOL DERIVATIVE; NANOPARTICLE; POLYETHYLENE DERIVATIVE; ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE;

ARTICLE; BIOCOMPATIBILITY; CELL ASSAY; CELL INTERACTION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; IMPLANT; INFLAMMATION; MACROPHAGE; MONOCYTE; NORMAL HUMAN; PARTICLE SIZE; CHEMISTRY; MATERIALS TESTING; METABOLISM; PATHOLOGY; REPLACEMENT ARTHROPLASTY; TUMOR CELL LINE;

ARTHROPLASTY, REPLACEMENT; CELL LINE, TUMOR; COATED MATERIALS, BIOCOMPATIBLE; CYTOKINES; HUMANS; KETONES; MACROPHAGES; MATERIALS TESTING; NANOPARTICLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYETHYLENES;

EID: 84855419443     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.31974     Document Type: Article

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