Comparison of the response of primary murine peritoneal macrophages and the U937 human histiocytic cell line to challenge with in vitro generated clinically relevant UHMWPE particles

Bio-Medical Materials and Engineering

Volumn 10, Issue 3-4, 2000, Pages 229-240

  Bridget Matthews, J ^a   Green, Tim R ^a   Stone, Martin H ^b   Mike Wroblewski, B ^c   Fisher, John ^a   Ingham, Eileen ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b LEEDS GENERAL INFIRMARY   (United Kingdom)

^c WRIGHTINGTON HOSPITAL   (United Kingdom)

Author keywords

Biologic response; Cytokines; Macrophage; UHMWPE; Wear particles

Indexed keywords

CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; POLYETHYLENE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL CULTURE; CELL INTERACTION; CELL LINE; CELL POPULATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; HISTIOCYTE; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROPHAGE ACTIVATION; MEDIATOR RELEASE; MOUSE; NONHUMAN; OSTEOLYSIS; PARTICLE SIZE; PERITONEUM MACROPHAGE; PRIORITY JOURNAL;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELLS, CULTURED; CYTOKINES; DINOPROSTONE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C3H; POLYETHYLENE; POLYETHYLENES; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS;

EID: 0033638364     PISSN: 09592989     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Wear particles in total joint replacements and their role in periprosthetic osteolysis
2. Reactions of the articular capsule to wear products of artificial joint prostheses
3. The arthroscopic evaluation and characteristics of severe polyethylene wear in total knee arthroplasty
4. Histologic, biochemical and ion analysis of tissue and fluids retrieved during total hip arthroplasty
5. Cytokines and endosteal bone resorption in failed cemented total hip replacement
6. Synovial fluid IL-6 levels in total joint arthroplasty with osteolysis
7. Assessment of the role of GM-CSF in the cellular transformation and the development of erosive lesions around orthopaedic implants
8. The synovial-like membrane at the bone-cement interface in loose total hip replacements and its proposed role in bone lysis
9. Macrophage/particle interactions: Effect of size, composition and surface area
10. Interface failure dynamics: Osteoclastic and macrophage bone loss
11. Response of three routine macrophage populations to particulate debris: Bone resorption in organ cultures
12. In vivo inflammatory response to polymethylmethacrylate particulate debris: Effect of size, morphology and surface area
13. Ultra-high molecular weight polyethylene wear debris generated in vivo and in laboratory tests; the influence of counterface roughness
14. Isolation of predominantly submicron-sized UHMWPE wear particles from periprosthetic tissues
15. Quantitative analysis of polyethylene wear debris, wear rate and head damage in retrieved Charnley hip prostheses
16. Polyethylene wear debris and tissue reactions in knee as compared to hip replacement prostheses
17. Biochemical and morphological analysis of activated human macrophages and fibroblasts by human polyethylene particles
18. Effects of polyethylene on macrophages
19. Human monocyte response to submicron fabricated and retrieved polyethylene, Ti-6AL-4V and Ti particles
20. Effects of phagocytosis of polyethylene particles on macrophage line IC-21 cells
21. Macrophage phagocytosis of polyethylene particulate in vitro
22. Human macrophage response to polyethylene particles in vitro: A new experimental model
23. Effect of ultra high molecular weight polyethylene wear debris on synoviocytes propagated in microcarrier spinner culture
24. Production of TNFα and nitric oxide by macrophages stimulated with particles and LPS
25. Measurement and removal of adherent endotoxin from titanium particles and implant surfaces
26. Stimulation of cytokine production by titanium wear particles is due to adherent endotoxin
27. The effect of endotoxin on the inflammatory response to particulate debris
28. Adsorbed endotoxin mediates differential effects on particle-induced stimulation of cytokine and chemokine release
29. The role of adherent endotoxin in stimulation of osteoclast differentiation by orthopaedic wear particles
30. Evaluation of the response of primary human peripheral blood mononuclear phagocytes to challenge with in vitro generated clinically relevant UHMWPE particles of known size and dose
31. Comparison of the response of three human monocytic cell lines to challenge with polyethylene particles of known size and dose
32. Polyethylene particles of a 'critical size' are necessary for the induction of cytokines by macrophages in vitro
33. Comparison of the response of primary human peripheral blood mononuclear phagocytes from different donors to challenge with polyethylene particles of known size and dose
34. The influence of lubricant on the morphology of ultra-high molecular weight polyethylene wear debris generated in laboratory tests
35. A study of the wear characteristics of ultra-high molecular weight polyethylene sliding against glass
36. The Enzyme Linked Immunosorbent Assay (ELISA)