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Volumn 188, Issue 1, 2012, Pages 472-476

Effects of systemic versus local administration of corticosteroids on mucosal tolerance

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CD3 ANTIGEN; CD4 ANTIGEN; CORTICOSTEROID; DEXAMETHASONE; IMMUNOGLOBULIN E; INTERLEUKIN 2 RECEPTOR ALPHA; PREDNISOLONE; TRANSCRIPTION FACTOR FOXP3;

EID: 84855391238     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101405     Document Type: Article
Times cited : (16)

References (39)
  • 2
    • 0030048946 scopus 로고    scopus 로고
    • Prednisolone treatment in asthma: Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa
    • Bentley, A. M., Q. Hamid, D. S. Robinson, E. Schotman, Q. Meng, B. Assoufi, A. B. Kay, and S. R. Durham. 1996. Prednisolone treatment in asthma: reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa. Am. J. Respir. Crit. Care Med. 153: 551-556.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 551-556
    • Bentley, A.M.1    Hamid, Q.2    Robinson, D.S.3    Schotman, E.4    Meng, Q.5    Assoufi, B.6    Kay, A.B.7    Durham, S.R.8
  • 4
    • 0031570475 scopus 로고    scopus 로고
    • + Lymphocytes
    • Blotta, M. H., R. H. DeKruyff, and D. T. Umetsu. 1997. Corticosteroids inhibit IL-12 production in human monocytes and enhance their capacity to induce IL-4 synthesis in CD4+ lymphocytes. J. Immunol. 158: 5589-5595. (Pubitemid 127483960)
    • (1997) Journal of Immunology , vol.158 , Issue.12 , pp. 5589-5595
    • Blotta, M.H.1    DeKruyff, R.H.2    Umetsu, D.T.3
  • 5
    • 0032031496 scopus 로고    scopus 로고
    • + lymphocytes by inhibiting IL-12 production
    • DeKruyff, R. H., Y. Fang, and D. T. Umetsu. 1998. Corticosteroids enhance the capacity of macrophages to induce Th2 cytokine synthesis in CD4+ lymphocytes by inhibiting IL-12 production. J. Immunol. 160: 2231-2237. (Pubitemid 28119903)
    • (1998) Journal of Immunology , vol.160 , Issue.5 , pp. 2231-2237
    • DeKruyff, R.H.1    Fang, Y.2    Umetsu, D.T.3
  • 6
    • 0032964286 scopus 로고    scopus 로고
    • Randomised controlled trial of budesonide for the prevention of post- bronchiolitis wheezing
    • Fox, G. F., M. L. Everard, M. J. Marsh, and A. D. Milner. 1999. Randomised controlled trial of budesonide for the prevention of post-bronchiolitis wheezing. Arch. Dis. Child. 80: 343-347. (Pubitemid 29164758)
    • (1999) Archives of Disease in Childhood , vol.80 , Issue.4 , pp. 343-347
    • Fox, G.F.1    Everard, M.L.2    Marsh, M.J.3    Milner, A.D.4
  • 8
    • 0036732461 scopus 로고    scopus 로고
    • Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
    • DOI 10.1038/nm745
    • Akbari, O., G. J. Freeman, E. H. Meyer, E. A. Greenfield, T. T. Chang, A. H. Sharpe, G. Berry, R. H. DeKruyff, and D. T. Umetsu. 2002. Antigenspecific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat. Med. 8: 1024-1032. (Pubitemid 35033708)
    • (2002) Nature Medicine , vol.8 , Issue.9 , pp. 1024-1032
    • Akbari, O.1    Freeman, G.J.2    Meyer, E.H.3    Greenfield, E.A.4    Chang, T.T.5    Sharpe, A.H.6    Berry, G.7    Dekruyff, R.H.8    Umetsu, D.T.9
  • 9
    • 9244223651 scopus 로고    scopus 로고
    • Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity
    • DOI 10.1038/ni1122
    • Stock, P., O. Akbari, G. Berry, G. J. Freeman, R. H. Dekruyff, and D. T. Umetsu. 2004. Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity. Nat. Immunol. 5: 1149-1156. (Pubitemid 39549629)
    • (2004) Nature Immunology , vol.5 , Issue.11 , pp. 1149-1156
    • Stock, P.1    Akbari, O.2    Berry, G.3    Freeman, G.J.4    DeKruyff, R.H.5    Umetsu, D.T.6
  • 10
    • 28244483190 scopus 로고    scopus 로고
    • Respiratory tolerance is inhibited by the administration of corticosteroids
    • Stock, P., O. Akbari, R. H. DeKruyff, and D. T. Umetsu. 2005. Respiratory tolerance is inhibited by the administration of corticosteroids. J. Immunol. 175: 7380-7387. (Pubitemid 41713435)
    • (2005) Journal of Immunology , vol.175 , Issue.11 , pp. 7380-7387
    • Stock, P.1    Akbari, O.2    DeKruyff, R.H.3    Umetsu, D.T.4
  • 12
    • 77949899445 scopus 로고    scopus 로고
    • A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity
    • Lombardi, V., P. Stock, A. K. Singh, J. Kerzerho, W. Yang, B. A. Sullivan, X. Li, T. Shiratsuchi, N. E. Hnatiuk, A. R. Howell, et al. 2010. A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity. J. Immunol. 184: 2107-2115.
    • (2010) J. Immunol. , vol.184 , pp. 2107-2115
    • Lombardi, V.1    Stock, P.2    Singh, A.K.3    Kerzerho, J.4    Yang, W.5    Sullivan, B.A.6    Li, X.7    Shiratsuchi, T.8    Hnatiuk, N.E.9    Howell, A.R.10
  • 14
    • 0034890907 scopus 로고    scopus 로고
    • Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen
    • DOI 10.1038/90667
    • Akbari, O., R. H. DeKruyff, and D. T. Umetsu. 2001. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat. Immunol. 2: 725-731. (Pubitemid 32747162)
    • (2001) Nature Immunology , vol.2 , Issue.8 , pp. 725-731
    • Akbari, O.1    DeKruyff, R.H.2    Umetsu, D.T.3
  • 15
    • 34147169116 scopus 로고    scopus 로고
    • T effectors outfox T regulators in autoimmunity
    • DOI 10.1038/nm0407-411, PII NM0407411
    • Prod'homme, T., M. S. Weber, and S. S. Zamvil. 2007. T effectors outfox T regulators in autoimmunity. Nat. Med. 13: 411-413. (Pubitemid 46559819)
    • (2007) Nature Medicine , vol.13 , Issue.4 , pp. 411-413
    • Prod'homme, T.1    Weber, M.S.2    Zamvil, S.S.3
  • 17
    • 0032473551 scopus 로고    scopus 로고
    • + T cells or interferon (IFN)-gamma in a murine model of allergen sensitization
    • DOI 10.1084/jem.187.5.721
    • Seymour, B. W., L. J. Gershwin, and R. L. Coffman. 1998. Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8+ or T cell receptor (TCR)-gamma/delta+ T cells or interferon (IFN)-gamma in a murine model of allergen sensitization. J. Exp. Med. 187: 721-731. (Pubitemid 28115188)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.5 , pp. 721-731
    • Seymour, B.W.P.1    Gershwin, L.J.2    Coffman, R.L.3
  • 18
    • 0031943945 scopus 로고    scopus 로고
    • Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1alpha, granulocyte-macrophage colony-stimulating factor, and interferon-gamma release from alveolar macrophages in asthma
    • John, M., S. Lim, J. Seybold, P. Jose, A. Robichaud, B. O'Connor, P. J. Barnes, and K. F. Chung. 1998. Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1alpha, granulocyte-macrophage colony-stimulating factor, and interferon-gamma release from alveolar macrophages in asthma. Am. J. Respir. Crit. Care Med. 157: 256-262. (Pubitemid 28071290)
    • (1998) American Journal of Respiratory and Critical Care Medicine , vol.157 , Issue.1 , pp. 256-262
    • John, M.1    Lim, S.2    Seybold, J.3    Jose, P.4    Robichaud, A.5    O'Connor, B.6    Barnes, P.J.7    Chung, K.F.8
  • 19
  • 20
    • 18744408211 scopus 로고    scopus 로고
    • A pharmacological approach to enhancing the therapeutic index of corticosteroids in airway inflammatory disease
    • DOI 10.1016/j.coph.2004.12.003, PII S1471489205000330
    • Uings, I. J., and S. N. Farrow. 2005. A pharmacological approach to enhancing the therapeutic index of corticosteroids in airway inflammatory disease. Curr. Opin. Pharmacol. 5: 221-226. (Pubitemid 40674242)
    • (2005) Current Opinion in Pharmacology , vol.5 , Issue.3 SPEC. ISS. , pp. 221-226
    • Uings, I.J.1    Farrow, S.N.2
  • 21
    • 0025871907 scopus 로고
    • Hydrocortisone and IL-4 induce IgE isotype switching in human B cells
    • Jabara, H. H., D. J. Ahern, D. Vercelli, and R. S. Geha. 1991. Hydrocortisone and IL-4 induce IgE isotype switching in human B cells. J. Immunol. 147: 1557-1560.
    • (1991) J. Immunol. , vol.147 , pp. 1557-1560
    • Jabara, H.H.1    Ahern, D.J.2    Vercelli, D.3    Geha, R.S.4
  • 22
    • 0027381450 scopus 로고
    • Sequential switching from mu to epsilon via gamma4 in human B cells stimulated with IL-4 and hydrocortisone
    • Jabara, H. H., R. Loh, N. Ramesh, D. Vercelli, and R. S. Geha. 1993. Sequential switching from mu to epsilon via gamma 4 in human B cells stimulated with IL- 4 and hydrocortisone. J. Immunol. 151: 4528-4533. (Pubitemid 23318506)
    • (1993) Journal of Immunology , vol.151 , Issue.9 , pp. 4528-4533
    • Jabara, H.H.1    Loh, R.2    Ramesh, N.3    Vercelli, D.4    Geha, R.S.5
  • 23
    • 0035138763 scopus 로고    scopus 로고
    • Glucocorticoids upregulate CD40 ligand expression and induce CD40L-dependent immunoglobulin isotype switching
    • Jabara, H. H., S. R. Brodeur, and R. S. Geha. 2001. Glucocorticoids upregulate CD40 ligand expression and induce CD40L-dependent immunoglobulin isotype switching. J. Clin. Invest. 107: 371-378. (Pubitemid 32157969)
    • (2001) Journal of Clinical Investigation , vol.107 , Issue.3 , pp. 371-378
    • Jabara, H.H.1    Brodeur, S.R.2    Geha, R.S.3
  • 24
    • 0028332762 scopus 로고
    • Synthetic glucocorticoids potentiate IgE synthesis. Influence of steroid and nonsteroid hormones on human in vitro IgE secretion
    • Nüsslein, H. G., G. Weber, and J. R. Kalden. 1994. Synthetic glucocorticoids potentiate IgE synthesis: influence of steroid and nonsteroid hormones on human in vitro IgE secretion. Allergy 49: 365-370. (Pubitemid 24163868)
    • (1994) Allergy: European Journal of Allergy and Clinical Immunology , vol.49 , Issue.5 , pp. 365-370
    • Nusslein, H.G.1    Weber, G.2    Kalden, J.R.3
  • 25
    • 0025944559 scopus 로고
    • Glucocorticoids suppress the production of interleukin 4 by human lymphocytes
    • Wu, C. Y., C. Fargeas, T. Nakajima, and G. Delespesse. 1991. Glucocorticoids suppress the production of interleukin 4 by human lymphocytes. Eur. J. Immunol. 21: 2645-2647.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2645-2647
    • Wu, C.Y.1    Fargeas, C.2    Nakajima, T.3    Delespesse, G.4
  • 28
    • 0034898199 scopus 로고    scopus 로고
    • Inhibition of human allergic T-cell responses by IL-10-treated dendritic cells: Differences from hydrocortisone-treated dendritic cells
    • DOI 10.1067/mai.2001.117177
    • Bellinghausen, I., U. Brand, K. Steinbrink, A. H. Enk, J. Knop, and J. Saloga. 2001. Inhibition of human allergic T-cell responses by IL-10-treated dendritic cells: differences from hydrocortisone-treated dendritic cells. J. Allergy Clin. Immunol. 108: 242-249. (Pubitemid 32735408)
    • (2001) Journal of Allergy and Clinical Immunology , vol.108 , Issue.2 , pp. 242-249
    • Bellinghausen, I.1    Brand, U.2    Steinbrink, K.3    Enk, A.H.4    Knop, J.5    Saloga, J.6
  • 29
    • 0033663565 scopus 로고    scopus 로고
    • Opposing effects of dehydroepiandrosterone and dexamethasone on the generation of monocyte-derived dendritic cells
    • Canning, M. O., K. Grotenhuis, H. J. de Wit, and H. A. Drexhage. 2000. Opposing effects of dehydroepiandrosterone and dexamethasone on the generation of monocyte-derived dendritic cells. Eur. J. Endocrinol. 143: 687-695.
    • (2000) Eur. J. Endocrinol. , vol.143 , pp. 687-695
    • Canning, M.O.1    Grotenhuis, K.2    De Wit, H.J.3    Drexhage, H.A.4
  • 30
    • 0032776071 scopus 로고    scopus 로고
    • Corticosteroids inhibit the production of inflammatory mediators in immature monocyte-derived DC and induce the development of tolerogenic DC3
    • de Jong, E. C., P. L. Vieira, P. Kalinski, and M. L. Kapsenberg. 1999. Corticosteroids inhibit the production of inflammatory mediators in immature monocyte-derived DC and induce the development of tolerogenic DC3. J. Leukoc. Biol. 66: 201-204. (Pubitemid 29379155)
    • (1999) Journal of Leukocyte Biology , vol.66 , Issue.2 , pp. 201-204
    • De Jong, E.C.1    Vieira, P.L.2    Kalinski, P.3    Kapsenberg, M.L.4
  • 31
    • 0034657913 scopus 로고    scopus 로고
    • Glucocorticoids transform CD40-triggering of dendritic cells into an alternative activation pathway resulting in antigen-presenting cells that secrete IL-10
    • Rea, D., C. van Kooten, K. E. van Meijgaarden, T. H. Ottenhoff, C. J. Melief, and R. Offringa. 2000. Glucocorticoids transform CD40-triggering of dendritic cells into an alternative activation pathway resulting in antigen-presenting cells that secrete IL-10. Blood 95: 3162-3167. (Pubitemid 30321168)
    • (2000) Blood , vol.95 , Issue.10 , pp. 3162-3167
    • Rea, D.1    Van Kooten, C.2    Van Meijgaarden, K.E.3    Ottenhoff, T.H.M.4    Melief, C.J.M.5    Offringa, R.6
  • 32
    • 0032533826 scopus 로고    scopus 로고
    • Glucocorticoids inhibit bioactive IL-12p70 production by in vitro- generated human dendritic cells without affecting their T cell stimulatory potential
    • Vieira, P. L., P. Kaliński, E. A. Wierenga, M. L. Kapsenberg, and E. C. de Jong. 1998. Glucocorticoids inhibit bioactive IL-12p70 production by in vitrogenerated human dendritic cells without affecting their T cell stimulatory potential. J. Immunol. 161: 5245-5251. (Pubitemid 28519083)
    • (1998) Journal of Immunology , vol.161 , Issue.10 , pp. 5245-5251
    • Vieira, P.L.1    Kalinski, P.2    Wierenga, E.A.3    Kapsenberg, M.L.4    De Jong, E.C.5
  • 33
    • 0032101532 scopus 로고    scopus 로고
    • Differential regulation of interleukin-10 (IL-10) and IL-12 by glucocorticoids in vitro
    • Visser, J., A. van Boxel-Dezaire, D. Methorst, T. Brunt, E. R. de Kloet, and L. Nagelkerken. 1998. Differential regulation of interleukin-10 (IL-10) and IL-12 by glucocorticoids in vitro. Blood 91: 4255-4264. (Pubitemid 28261990)
    • (1998) Blood , vol.91 , Issue.11 , pp. 4255-4264
    • Visser, J.1    Van Boxel-Dezaire, A.2    Methorst, D.3    Brunt, T.4    De Kloet, E.R.5    Nagelkerken, L.6
  • 34
    • 0036467451 scopus 로고    scopus 로고
    • Direct and indirect inhibition of Th1 development by progesterone and glucocorticoids
    • Miyaura, H., and M. Iwata. 2002. Direct and indirect inhibition of Th1 development by progesterone and glucocorticoids. J. Immunol. 168: 1087-1094. (Pubitemid 34094472)
    • (2002) Journal of Immunology , vol.168 , Issue.3 , pp. 1087-1094
    • Miyaura, H.1    Iwata, M.2
  • 35
    • 0021924295 scopus 로고
    • Effect of dexamethasone on de novo IgE synthesis by human blood lymphocytes
    • DOI 10.1016/0091-6749(85)90062-4
    • Hemady, Z., S. Gellis, M. Chambers, and R. E. Rocklin. 1985. Effect of dexamethasone on de novo IgE synthesis by human blood lymphocytes. J. Allergy Clin. Immunol. 75: 304-312. (Pubitemid 15239086)
    • (1985) Journal of Allergy and Clinical Immunology , vol.75 , Issue.2 , pp. 304-312
    • Hemady, Z.1    Gellis, S.2    Chambers, M.3    Rocklin, R.E.4
  • 37
    • 0019377972 scopus 로고
    • Deposition of pressurised aerosols in the human respiratory tract
    • Newman, S. P., D. Pavia, F. Morén, N. F. Sheahan, and S. W. Clarke. 1981. Deposition of pressurised aerosols in the human respiratory tract. Thorax 36: 52-55. (Pubitemid 11188675)
    • (1981) Thorax , vol.36 , Issue.1 , pp. 52-55
    • Newman, S.P.1    Pavia, D.2    Moren, F.3
  • 39
    • 0041735102 scopus 로고    scopus 로고
    • Regulatory T cells control the development of allergic disease and asthma
    • quiz 488
    • Umetsu, D. T., O. Akbari, and R. H. Dekruyff. 2003. Regulatory T cells control the development of allergic disease and asthma. J. Allergy Clin. Immunol. 112: 480-487, quiz 488.
    • (2003) J. Allergy Clin. Immunol. , vol.112 , pp. 480-487
    • Umetsu, D.T.1    Akbari, O.2    Dekruyff, R.H.3


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