A comparison of two human cell lines and two rat gonadal cell primary cultures as in vitro screening tools for aromatase modulation

Toxicology in Vitro

Volumn 26, Issue 1, 2012, Pages 107-118

  Quignot, Nadia ^a   Desmots, Sophie ^a   Barouki, Robert ^b,c   Lemazurier, Emmanuel ^a  

^a INSTITUT NATIONAL DE L ENVIRONNEMENT INDUSTRIEL ET DES RISQUES INERIS   (France)

^b INSERM   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Aromatase; Endocrine disrupting chemicals; In vitro models; Risk assessment; Toxicity

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; AROMATASE; ATRAZINE; BIOLOGICAL MARKER; ENDOCRINE DISRUPTOR; MESSENGER RNA; METHOXYCHLOR; VINCLOZOLIN;

ADRENAL CORTEX CARCINOMA; ANIMAL CELL; ARTICLE; CANCER CELL; CELL CULTURE; CELL ISOLATION; CHORIOCARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME REGULATION; FEMALE; GONAD; GRANULOSA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEYDIG CELL; NONHUMAN; PROTEIN EXPRESSION; RAT; SCREENING TEST; SPECIES DIFFERENCE; STEROIDOGENESIS;

ANDROGEN ANTAGONISTS; ANIMALS; AROMATASE; ATRAZINE; CELL LINE, TUMOR; CELLS, CULTURED; ENDOCRINE DISRUPTORS; ESTROGENS, NON-STEROIDAL; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GRANULOSA CELLS; HUMANS; LEYDIG CELLS; MALE; METHOXYCHLOR; OXAZOLES; PHENOLS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

RATTUS;

EID: 84855347940     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.11.004     Document Type: Article

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