-
1
-
-
0036374410
-
Aromatase and its inhibitors: significance for breast cancer therapy
-
Simpson E.R., Dowsett M. Aromatase and its inhibitors: significance for breast cancer therapy. Recent Prog Horm Res 2002, 57(1):317-338.
-
(2002)
Recent Prog Horm Res
, vol.57
, Issue.1
, pp. 317-338
-
-
Simpson, E.R.1
Dowsett, M.2
-
2
-
-
0034106868
-
Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro
-
Vinggaard A.M., Hnida C., Breinholt V., Larsen J.C. Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro. Toxicol In Vitro 2000, 14(3):227-234.
-
(2000)
Toxicol In Vitro
, vol.14
, Issue.3
, pp. 227-234
-
-
Vinggaard, A.M.1
Hnida, C.2
Breinholt, V.3
Larsen, J.C.4
-
3
-
-
67449136137
-
History of aromatase: saga of an important biological mediator and therapeutic target
-
Santen R.J.B.H., Simpson E.R., Siiteri P.K., Brodie A. History of aromatase: saga of an important biological mediator and therapeutic target. Endocrinol Rev 2009, 30(4):343-375.
-
(2009)
Endocrinol Rev
, vol.30
, Issue.4
, pp. 343-375
-
-
Santen, R.J.B.H.1
Simpson, E.R.2
Siiteri, P.K.3
Brodie, A.4
-
4
-
-
0035184359
-
Effects of chloro-s-triazine herbicides and metabolites on aromatase activity in various human cell lines and on vitellogenin production in male carp hepatocytes
-
Sanderson J.T.L.R., Heneweer M., Giesy J.P., van den Berg M. Effects of chloro-s-triazine herbicides and metabolites on aromatase activity in various human cell lines and on vitellogenin production in male carp hepatocytes. Environ Health Perspect 2001, 109(10):1027-1031.
-
(2001)
Environ Health Perspect
, vol.109
, Issue.10
, pp. 1027-1031
-
-
Sanderson, J.T.L.R.1
Heneweer, M.2
Giesy, J.P.3
van den Berg, M.4
-
5
-
-
0034106718
-
2-Chloro-s-triazine herbicides induce aromatase (CYP19) activity in H295R human adrenocortical carcinoma cells: a novel mechanism for estrogenicity?
-
Sanderson J.T., Seinen W., Giesy J.P., van den Berg M. 2-Chloro-s-triazine herbicides induce aromatase (CYP19) activity in H295R human adrenocortical carcinoma cells: a novel mechanism for estrogenicity?. Toxicol Sci 2000, 54(1):121-127.
-
(2000)
Toxicol Sci
, vol.54
, Issue.1
, pp. 121-127
-
-
Sanderson, J.T.1
Seinen, W.2
Giesy, J.P.3
van den Berg, M.4
-
7
-
-
0345276652
-
A comparison of human H295R and rat R2C cell lines as in vitro screening tools for effects on aromatase
-
Heneweer M., van den Berg M., Sanderson J.T. A comparison of human H295R and rat R2C cell lines as in vitro screening tools for effects on aromatase. Toxicol Lett 2004, 146(2):183-194.
-
(2004)
Toxicol Lett
, vol.146
, Issue.2
, pp. 183-194
-
-
Heneweer, M.1
van den Berg, M.2
Sanderson, J.T.3
-
8
-
-
33750009766
-
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line
-
Laville N., Balaguer P., Brion F., Hinfray N., Casellas C., Porcher J.M., et al. Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line. Toxicology 2006, 228(1):98-108.
-
(2006)
Toxicology
, vol.228
, Issue.1
, pp. 98-108
-
-
Laville, N.1
Balaguer, P.2
Brion, F.3
Hinfray, N.4
Casellas, C.5
Porcher, J.M.6
-
9
-
-
42049121649
-
Atrazine-induced changes in aromatase activity in estrogen sensitive target tissues
-
Holloway A.C., Anger D.A., Crankshaw D.J., Wu M., Foster W.G. Atrazine-induced changes in aromatase activity in estrogen sensitive target tissues. J Appl Toxicol 2008, 28(3):260-270.
-
(2008)
J Appl Toxicol
, vol.28
, Issue.3
, pp. 260-270
-
-
Holloway, A.C.1
Anger, D.A.2
Crankshaw, D.J.3
Wu, M.4
Foster, W.G.5
-
10
-
-
0033753131
-
The effect of atrazine on puberty in male wistar rats: an evaluation in the protocol for the assessment of pubertal development and thyroid function
-
Stoker T.E., Laws S.C., Guidici D.L., Cooper R.L. The effect of atrazine on puberty in male wistar rats: an evaluation in the protocol for the assessment of pubertal development and thyroid function. Toxicol Sci 2000, 58(1):50-59.
-
(2000)
Toxicol Sci
, vol.58
, Issue.1
, pp. 50-59
-
-
Stoker, T.E.1
Laws, S.C.2
Guidici, D.L.3
Cooper, R.L.4
-
11
-
-
79952102201
-
The role of testicular aromatase in the atrazine mediated changes in estrone and estradiol in the male wistar rat
-
Available from
-
Modic MW. The role of testicular aromatase in the atrazine mediated changes in estrone and estradiol in the male wistar rat; 2004. Available from: http://www.lib.ncsu.edu/theses/available/etd-08052004-132003/unrestricted/etd.pdf.
-
(2004)
-
-
Modic, M.W.1
-
12
-
-
79952102524
-
Effects of pesticides on aromatase expression in bioluminescent mice and GSK 3BETA/BETA-signalling in LNCAp human prostate cancer cells
-
Rivest P.S.J. Effects of pesticides on aromatase expression in bioluminescent mice and GSK 3BETA/BETA-signalling in LNCAp human prostate cancer cells. The Toxicologist 2010, 114:p405.
-
(2010)
The Toxicologist
, vol.114
-
-
Rivest, P.S.J.1
-
13
-
-
0141730408
-
Modeling and predicting immunological effects of chemical stressors: characterization of a quantitative biomarker for immunological changes caused by atrazine and ethanol
-
Pruett S.B., Fan R., Zheng Q., Myers L.P., Hebert P. Modeling and predicting immunological effects of chemical stressors: characterization of a quantitative biomarker for immunological changes caused by atrazine and ethanol. Toxicol Sci 2003, 75(2):343-354.
-
(2003)
Toxicol Sci
, vol.75
, Issue.2
, pp. 343-354
-
-
Pruett, S.B.1
Fan, R.2
Zheng, Q.3
Myers, L.P.4
Hebert, P.5
-
14
-
-
66149120226
-
Patterns of immunotoxicity associated with chronic as compared with acute exposure to chemical or physical stressors and their relevance with regard to the role of stress and with regard to immunotoxicity testing
-
Pruett S.B., Fan R., Zheng Q., Schwab C. Patterns of immunotoxicity associated with chronic as compared with acute exposure to chemical or physical stressors and their relevance with regard to the role of stress and with regard to immunotoxicity testing. Toxicol Sci 2009, 109(2):265-275.
-
(2009)
Toxicol Sci
, vol.109
, Issue.2
, pp. 265-275
-
-
Pruett, S.B.1
Fan, R.2
Zheng, Q.3
Schwab, C.4
-
15
-
-
71049155306
-
Chlorotriazine herbicides and metabolites activate an ACTH-dependent release of corticosterone in male Wistar rats
-
Laws S.C., Hotchkiss M., Ferrell J., Jayaraman S., Mills L., Modic W., et al. Chlorotriazine herbicides and metabolites activate an ACTH-dependent release of corticosterone in male Wistar rats. Toxicol Sci 2009, 112(1):78-87.
-
(2009)
Toxicol Sci
, vol.112
, Issue.1
, pp. 78-87
-
-
Laws, S.C.1
Hotchkiss, M.2
Ferrell, J.3
Jayaraman, S.4
Mills, L.5
Modic, W.6
-
16
-
-
71049143917
-
Characterization of the hypothalamic-pituitary-adrenal axis response to atrazine and metabolites in the female rat
-
Fraites M.J.P., Cooper R.L., Buckalew A., Jayaraman S., Mills L., Laws S.C. Characterization of the hypothalamic-pituitary-adrenal axis response to atrazine and metabolites in the female rat. Toxicol Sci 2009, 112(1):88-99.
-
(2009)
Toxicol Sci
, vol.112
, Issue.1
, pp. 88-99
-
-
Fraites, M.J.P.1
Cooper, R.L.2
Buckalew, A.3
Jayaraman, S.4
Mills, L.5
Laws, S.C.6
-
17
-
-
34248582409
-
Reproductive function: mode and mechanism of action studies
-
Cooper R.L., Das L.S., Narotsky P.C., Goldman M.G., Tyrey J.M., Stoker T.E., Atrazine Reproductive function: mode and mechanism of action studies. Birth Defects Res 2007, 80:98-112.
-
(2007)
Birth Defects Res
, vol.80
, pp. 98-112
-
-
Cooper, R.L.1
Das, L.S.2
Narotsky, P.C.3
Goldman, M.G.4
Tyrey, J.M.5
Stoker, T.E.6
Atrazine7
-
18
-
-
47749146539
-
The herbicide atrazine activates endocrine gene networks via non-steroidal NR5A nuclear receptors in fish and mammalian cells
-
Suzawa M., Ingraham H.A. The herbicide atrazine activates endocrine gene networks via non-steroidal NR5A nuclear receptors in fish and mammalian cells. PLoS ONE 2008, 3(5):pe2117.
-
(2008)
PLoS ONE
, vol.3
, Issue.5
-
-
Suzawa, M.1
Ingraham, H.A.2
-
19
-
-
84864062497
-
U.S. EPA OSCPP's harmonized test guidelines
-
Series 890, endocrine disruptor screening program, 890-150 steroidogenesis assay (Human H295R cells)
-
U.S. EPA OSCPP's harmonized test guidelines. Series 890, endocrine disruptor screening program, 890-150 steroidogenesis assay (Human H295R cells); 2009. http://www.epa.gov/ocspp/pubs/frs/publications/Test_Guidelines/series890.htm.
-
(2009)
-
-
-
20
-
-
0034788874
-
Effects of androstenedione, insulin and luteinizing hormone on steroidogenesis in human granulosa luteal cells
-
Greisen S., Ledet T., Ovesen P. Effects of androstenedione, insulin and luteinizing hormone on steroidogenesis in human granulosa luteal cells. Hum Reprod 2001, 16(10):2061-2065.
-
(2001)
Hum Reprod
, vol.16
, Issue.10
, pp. 2061-2065
-
-
Greisen, S.1
Ledet, T.2
Ovesen, P.3
-
22
-
-
34248335900
-
The OECD Validation program of the H295R steriodogenesis assay for the identification of in vitro inhibitors and inducers of testosterone and estradiol production. Phase 2: inter-laboratory pre-validation studies
-
special issue 1
-
Hecker M., Hollert H., Cooper R., Vinggaard A.-M., Akahori Y., Murphy M., Nellemann C., Higley E., Newsted J., Wu R., Lam P., Laskey J., Buckalew A., Grund S., Nakai M., Timm G., Giesy J. The OECD Validation program of the H295R steriodogenesis assay for the identification of in vitro inhibitors and inducers of testosterone and estradiol production. Phase 2: inter-laboratory pre-validation studies. Env Sci Pollut Res 2007, 14(special issue 1):23-30.
-
(2007)
Env Sci Pollut Res
, vol.14
, pp. 23-30
-
-
Hecker, M.1
Hollert, H.2
Cooper, R.3
Vinggaard, A.-M.4
Akahori, Y.5
Murphy, M.6
Nellemann, C.7
Higley, E.8
Newsted, J.9
Wu, R.10
Lam, P.11
Laskey, J.12
Buckalew, A.13
Grund, S.14
Nakai, M.15
Timm, G.16
Giesy, J.17
-
23
-
-
0344197425
-
Quantitative identification of atrazine in plasma
-
Brzezicki J.M., Andersen M.E., Cranmer B.K., Tessari J.D. Quantitative identification of atrazine in plasma. J. Anal. Toxicol. 2003, 27(8):569-573.
-
(2003)
J. Anal. Toxicol.
, vol.27
, Issue.8
, pp. 569-573
-
-
Brzezicki, J.M.1
Andersen, M.E.2
Cranmer, B.K.3
Tessari, J.D.4
-
24
-
-
33847774717
-
Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II
-
Fan W., Yanase T., Morinaga H., Gondo S., Okabe T., Nomura M., et al. Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II. Biochem Biophys Res Commun 2007, 355(4):1012-1018.
-
(2007)
Biochem Biophys Res Commun
, vol.355
, Issue.4
, pp. 1012-1018
-
-
Fan, W.1
Yanase, T.2
Morinaga, H.3
Gondo, S.4
Okabe, T.5
Nomura, M.6
-
25
-
-
0025074978
-
Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis
-
Gazdar A.F., Ole H.K., Shackleton C.H., Chen T.R., Triche T.J., Myers C.E., et al. Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis. Cancer Res 1990, 50(17):5488-5496.
-
(1990)
Cancer Res
, vol.50
, Issue.17
, pp. 5488-5496
-
-
Gazdar, A.F.1
Ole, H.K.2
Shackleton, C.H.3
Chen, T.R.4
Triche, T.J.5
Myers, C.E.6
-
26
-
-
73249121077
-
Molecular mechanism for repression of 17{alpha}-hydroxylase expression and androstenedione production in granulosa cells
-
Patel S.S., Beshay V.E., Escobar J.C., Suzuki T., Carr B.R. Molecular mechanism for repression of 17{alpha}-hydroxylase expression and androstenedione production in granulosa cells. J Clin Endocrinol Metab 2009, 94(12):5163-5168.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, Issue.12
, pp. 5163-5168
-
-
Patel, S.S.1
Beshay, V.E.2
Escobar, J.C.3
Suzuki, T.4
Carr, B.R.5
-
27
-
-
34548862307
-
Oral absorption and ovidative metabolism of atrazine in rats evaluated by physiological modeling approaches
-
McMullin, Hannerman W.h., Carnmer B.K., Tessari J.D., Andersen M.E. Oral absorption and ovidative metabolism of atrazine in rats evaluated by physiological modeling approaches. Toxicology 2007, 240:p1-14.
-
(2007)
Toxicology
, vol.240
-
-
McMullin1
Hannerman, W.2
Carnmer, B.K.3
Tessari, J.D.4
Andersen, M.E.5
-
28
-
-
0030198324
-
Effect of atrazine on ovarian function in the rat
-
Cooper R.L., Stoker T.E., Goldman J.M., Parrish M.B., Tyrey L. Effect of atrazine on ovarian function in the rat. Reprod Toxicol 1996, 10(4):257-264.
-
(1996)
Reprod Toxicol
, vol.10
, Issue.4
, pp. 257-264
-
-
Cooper, R.L.1
Stoker, T.E.2
Goldman, J.M.3
Parrish, M.B.4
Tyrey, L.5
-
29
-
-
77958455522
-
Upregulation of peripubertal rat leydig cell steroidogenesis following 24 h in vitro and in vivo exposure to atrazine
-
first published online July 28, 2010 doi:10.1093/toxsci/kfq227
-
Pogrmic-Majkic K., Fa S., Dakic V., Kaisarevic S., Kovacevic R. Upregulation of peripubertal rat leydig cell steroidogenesis following 24 h in vitro and in vivo exposure to atrazine. Toxicol Sci 2010, 118(1):52-60. first published online July 28, 2010 doi:10.1093/toxsci/kfq227.
-
(2010)
Toxicol Sci
, vol.118
, Issue.1
, pp. 52-60
-
-
Pogrmic-Majkic, K.1
Fa, S.2
Dakic, V.3
Kaisarevic, S.4
Kovacevic, R.5
|