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Volumn 31, Issue 2, 2011, Pages 184-193

Understanding the effects of atrazine on steroidogenesis in rat granulosa and H295R adrenal cortical carcinoma cells

Author keywords

Atrazine; Chlorotriazine herbicides; Estradiol; Granulosa cells; Progesterone; Steroidogenesis

Indexed keywords

AROMATASE; ATRAZINE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); ESTRADIOL; ESTROGEN; ESTRONE; ESTRONE SULFATE; PROGESTERONE; STEROID; TESTOSTERONE;

EID: 79952105159     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2010.11.005     Document Type: Article
Times cited : (53)

References (29)
  • 1
    • 0036374410 scopus 로고    scopus 로고
    • Aromatase and its inhibitors: significance for breast cancer therapy
    • Simpson E.R., Dowsett M. Aromatase and its inhibitors: significance for breast cancer therapy. Recent Prog Horm Res 2002, 57(1):317-338.
    • (2002) Recent Prog Horm Res , vol.57 , Issue.1 , pp. 317-338
    • Simpson, E.R.1    Dowsett, M.2
  • 2
    • 0034106868 scopus 로고    scopus 로고
    • Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro
    • Vinggaard A.M., Hnida C., Breinholt V., Larsen J.C. Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro. Toxicol In Vitro 2000, 14(3):227-234.
    • (2000) Toxicol In Vitro , vol.14 , Issue.3 , pp. 227-234
    • Vinggaard, A.M.1    Hnida, C.2    Breinholt, V.3    Larsen, J.C.4
  • 3
    • 67449136137 scopus 로고    scopus 로고
    • History of aromatase: saga of an important biological mediator and therapeutic target
    • Santen R.J.B.H., Simpson E.R., Siiteri P.K., Brodie A. History of aromatase: saga of an important biological mediator and therapeutic target. Endocrinol Rev 2009, 30(4):343-375.
    • (2009) Endocrinol Rev , vol.30 , Issue.4 , pp. 343-375
    • Santen, R.J.B.H.1    Simpson, E.R.2    Siiteri, P.K.3    Brodie, A.4
  • 4
    • 0035184359 scopus 로고    scopus 로고
    • Effects of chloro-s-triazine herbicides and metabolites on aromatase activity in various human cell lines and on vitellogenin production in male carp hepatocytes
    • Sanderson J.T.L.R., Heneweer M., Giesy J.P., van den Berg M. Effects of chloro-s-triazine herbicides and metabolites on aromatase activity in various human cell lines and on vitellogenin production in male carp hepatocytes. Environ Health Perspect 2001, 109(10):1027-1031.
    • (2001) Environ Health Perspect , vol.109 , Issue.10 , pp. 1027-1031
    • Sanderson, J.T.L.R.1    Heneweer, M.2    Giesy, J.P.3    van den Berg, M.4
  • 5
    • 0034106718 scopus 로고    scopus 로고
    • 2-Chloro-s-triazine herbicides induce aromatase (CYP19) activity in H295R human adrenocortical carcinoma cells: a novel mechanism for estrogenicity?
    • Sanderson J.T., Seinen W., Giesy J.P., van den Berg M. 2-Chloro-s-triazine herbicides induce aromatase (CYP19) activity in H295R human adrenocortical carcinoma cells: a novel mechanism for estrogenicity?. Toxicol Sci 2000, 54(1):121-127.
    • (2000) Toxicol Sci , vol.54 , Issue.1 , pp. 121-127
    • Sanderson, J.T.1    Seinen, W.2    Giesy, J.P.3    van den Berg, M.4
  • 7
    • 0345276652 scopus 로고    scopus 로고
    • A comparison of human H295R and rat R2C cell lines as in vitro screening tools for effects on aromatase
    • Heneweer M., van den Berg M., Sanderson J.T. A comparison of human H295R and rat R2C cell lines as in vitro screening tools for effects on aromatase. Toxicol Lett 2004, 146(2):183-194.
    • (2004) Toxicol Lett , vol.146 , Issue.2 , pp. 183-194
    • Heneweer, M.1    van den Berg, M.2    Sanderson, J.T.3
  • 8
    • 33750009766 scopus 로고    scopus 로고
    • Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line
    • Laville N., Balaguer P., Brion F., Hinfray N., Casellas C., Porcher J.M., et al. Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line. Toxicology 2006, 228(1):98-108.
    • (2006) Toxicology , vol.228 , Issue.1 , pp. 98-108
    • Laville, N.1    Balaguer, P.2    Brion, F.3    Hinfray, N.4    Casellas, C.5    Porcher, J.M.6
  • 9
    • 42049121649 scopus 로고    scopus 로고
    • Atrazine-induced changes in aromatase activity in estrogen sensitive target tissues
    • Holloway A.C., Anger D.A., Crankshaw D.J., Wu M., Foster W.G. Atrazine-induced changes in aromatase activity in estrogen sensitive target tissues. J Appl Toxicol 2008, 28(3):260-270.
    • (2008) J Appl Toxicol , vol.28 , Issue.3 , pp. 260-270
    • Holloway, A.C.1    Anger, D.A.2    Crankshaw, D.J.3    Wu, M.4    Foster, W.G.5
  • 10
    • 0033753131 scopus 로고    scopus 로고
    • The effect of atrazine on puberty in male wistar rats: an evaluation in the protocol for the assessment of pubertal development and thyroid function
    • Stoker T.E., Laws S.C., Guidici D.L., Cooper R.L. The effect of atrazine on puberty in male wistar rats: an evaluation in the protocol for the assessment of pubertal development and thyroid function. Toxicol Sci 2000, 58(1):50-59.
    • (2000) Toxicol Sci , vol.58 , Issue.1 , pp. 50-59
    • Stoker, T.E.1    Laws, S.C.2    Guidici, D.L.3    Cooper, R.L.4
  • 11
    • 79952102201 scopus 로고    scopus 로고
    • The role of testicular aromatase in the atrazine mediated changes in estrone and estradiol in the male wistar rat
    • Available from
    • Modic MW. The role of testicular aromatase in the atrazine mediated changes in estrone and estradiol in the male wistar rat; 2004. Available from: http://www.lib.ncsu.edu/theses/available/etd-08052004-132003/unrestricted/etd.pdf.
    • (2004)
    • Modic, M.W.1
  • 12
    • 79952102524 scopus 로고    scopus 로고
    • Effects of pesticides on aromatase expression in bioluminescent mice and GSK 3BETA/BETA-signalling in LNCAp human prostate cancer cells
    • Rivest P.S.J. Effects of pesticides on aromatase expression in bioluminescent mice and GSK 3BETA/BETA-signalling in LNCAp human prostate cancer cells. The Toxicologist 2010, 114:p405.
    • (2010) The Toxicologist , vol.114
    • Rivest, P.S.J.1
  • 13
    • 0141730408 scopus 로고    scopus 로고
    • Modeling and predicting immunological effects of chemical stressors: characterization of a quantitative biomarker for immunological changes caused by atrazine and ethanol
    • Pruett S.B., Fan R., Zheng Q., Myers L.P., Hebert P. Modeling and predicting immunological effects of chemical stressors: characterization of a quantitative biomarker for immunological changes caused by atrazine and ethanol. Toxicol Sci 2003, 75(2):343-354.
    • (2003) Toxicol Sci , vol.75 , Issue.2 , pp. 343-354
    • Pruett, S.B.1    Fan, R.2    Zheng, Q.3    Myers, L.P.4    Hebert, P.5
  • 14
    • 66149120226 scopus 로고    scopus 로고
    • Patterns of immunotoxicity associated with chronic as compared with acute exposure to chemical or physical stressors and their relevance with regard to the role of stress and with regard to immunotoxicity testing
    • Pruett S.B., Fan R., Zheng Q., Schwab C. Patterns of immunotoxicity associated with chronic as compared with acute exposure to chemical or physical stressors and their relevance with regard to the role of stress and with regard to immunotoxicity testing. Toxicol Sci 2009, 109(2):265-275.
    • (2009) Toxicol Sci , vol.109 , Issue.2 , pp. 265-275
    • Pruett, S.B.1    Fan, R.2    Zheng, Q.3    Schwab, C.4
  • 15
    • 71049155306 scopus 로고    scopus 로고
    • Chlorotriazine herbicides and metabolites activate an ACTH-dependent release of corticosterone in male Wistar rats
    • Laws S.C., Hotchkiss M., Ferrell J., Jayaraman S., Mills L., Modic W., et al. Chlorotriazine herbicides and metabolites activate an ACTH-dependent release of corticosterone in male Wistar rats. Toxicol Sci 2009, 112(1):78-87.
    • (2009) Toxicol Sci , vol.112 , Issue.1 , pp. 78-87
    • Laws, S.C.1    Hotchkiss, M.2    Ferrell, J.3    Jayaraman, S.4    Mills, L.5    Modic, W.6
  • 16
    • 71049143917 scopus 로고    scopus 로고
    • Characterization of the hypothalamic-pituitary-adrenal axis response to atrazine and metabolites in the female rat
    • Fraites M.J.P., Cooper R.L., Buckalew A., Jayaraman S., Mills L., Laws S.C. Characterization of the hypothalamic-pituitary-adrenal axis response to atrazine and metabolites in the female rat. Toxicol Sci 2009, 112(1):88-99.
    • (2009) Toxicol Sci , vol.112 , Issue.1 , pp. 88-99
    • Fraites, M.J.P.1    Cooper, R.L.2    Buckalew, A.3    Jayaraman, S.4    Mills, L.5    Laws, S.C.6
  • 18
    • 47749146539 scopus 로고    scopus 로고
    • The herbicide atrazine activates endocrine gene networks via non-steroidal NR5A nuclear receptors in fish and mammalian cells
    • Suzawa M., Ingraham H.A. The herbicide atrazine activates endocrine gene networks via non-steroidal NR5A nuclear receptors in fish and mammalian cells. PLoS ONE 2008, 3(5):pe2117.
    • (2008) PLoS ONE , vol.3 , Issue.5
    • Suzawa, M.1    Ingraham, H.A.2
  • 19
    • 84864062497 scopus 로고    scopus 로고
    • U.S. EPA OSCPP's harmonized test guidelines
    • Series 890, endocrine disruptor screening program, 890-150 steroidogenesis assay (Human H295R cells)
    • U.S. EPA OSCPP's harmonized test guidelines. Series 890, endocrine disruptor screening program, 890-150 steroidogenesis assay (Human H295R cells); 2009. http://www.epa.gov/ocspp/pubs/frs/publications/Test_Guidelines/series890.htm.
    • (2009)
  • 20
    • 0034788874 scopus 로고    scopus 로고
    • Effects of androstenedione, insulin and luteinizing hormone on steroidogenesis in human granulosa luteal cells
    • Greisen S., Ledet T., Ovesen P. Effects of androstenedione, insulin and luteinizing hormone on steroidogenesis in human granulosa luteal cells. Hum Reprod 2001, 16(10):2061-2065.
    • (2001) Hum Reprod , vol.16 , Issue.10 , pp. 2061-2065
    • Greisen, S.1    Ledet, T.2    Ovesen, P.3
  • 21
  • 24
    • 33847774717 scopus 로고    scopus 로고
    • Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II
    • Fan W., Yanase T., Morinaga H., Gondo S., Okabe T., Nomura M., et al. Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II. Biochem Biophys Res Commun 2007, 355(4):1012-1018.
    • (2007) Biochem Biophys Res Commun , vol.355 , Issue.4 , pp. 1012-1018
    • Fan, W.1    Yanase, T.2    Morinaga, H.3    Gondo, S.4    Okabe, T.5    Nomura, M.6
  • 25
    • 0025074978 scopus 로고
    • Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis
    • Gazdar A.F., Ole H.K., Shackleton C.H., Chen T.R., Triche T.J., Myers C.E., et al. Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis. Cancer Res 1990, 50(17):5488-5496.
    • (1990) Cancer Res , vol.50 , Issue.17 , pp. 5488-5496
    • Gazdar, A.F.1    Ole, H.K.2    Shackleton, C.H.3    Chen, T.R.4    Triche, T.J.5    Myers, C.E.6
  • 26
    • 73249121077 scopus 로고    scopus 로고
    • Molecular mechanism for repression of 17{alpha}-hydroxylase expression and androstenedione production in granulosa cells
    • Patel S.S., Beshay V.E., Escobar J.C., Suzuki T., Carr B.R. Molecular mechanism for repression of 17{alpha}-hydroxylase expression and androstenedione production in granulosa cells. J Clin Endocrinol Metab 2009, 94(12):5163-5168.
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.12 , pp. 5163-5168
    • Patel, S.S.1    Beshay, V.E.2    Escobar, J.C.3    Suzuki, T.4    Carr, B.R.5
  • 27
    • 34548862307 scopus 로고    scopus 로고
    • Oral absorption and ovidative metabolism of atrazine in rats evaluated by physiological modeling approaches
    • McMullin, Hannerman W.h., Carnmer B.K., Tessari J.D., Andersen M.E. Oral absorption and ovidative metabolism of atrazine in rats evaluated by physiological modeling approaches. Toxicology 2007, 240:p1-14.
    • (2007) Toxicology , vol.240
    • McMullin1    Hannerman, W.2    Carnmer, B.K.3    Tessari, J.D.4    Andersen, M.E.5
  • 29
    • 77958455522 scopus 로고    scopus 로고
    • Upregulation of peripubertal rat leydig cell steroidogenesis following 24 h in vitro and in vivo exposure to atrazine
    • first published online July 28, 2010 doi:10.1093/toxsci/kfq227
    • Pogrmic-Majkic K., Fa S., Dakic V., Kaisarevic S., Kovacevic R. Upregulation of peripubertal rat leydig cell steroidogenesis following 24 h in vitro and in vivo exposure to atrazine. Toxicol Sci 2010, 118(1):52-60. first published online July 28, 2010 doi:10.1093/toxsci/kfq227.
    • (2010) Toxicol Sci , vol.118 , Issue.1 , pp. 52-60
    • Pogrmic-Majkic, K.1    Fa, S.2    Dakic, V.3    Kaisarevic, S.4    Kovacevic, R.5


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