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Volumn 125, Issue 1, 2011, Pages 243-252

Aromatase immunoreactivity is increased in mammographically dense regions of the breast

Author keywords

Aromatase; Breast density; Dense area

Indexed keywords

AROMATASE; BIOTIN; ESTROGEN; STREPTAVIDIN;

EID: 78651096592     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-0944-6     Document Type: Article
Times cited : (48)

References (38)
  • 1
    • 34250825448 scopus 로고    scopus 로고
    • Comparison of a new and existing method of mammographic density measurement: Intramethod reliability and associations with known risk factors
    • DOI 10.1158/1055-9965.EPI-07-0085
    • VA McCormack R Highnam N Perry I dos Santos Silva 2007 Comparison of a new and existing method of mammographic density measurement: intramethod reliability and associations with known risk factors Cancer Epidemiol Biomarkers Prev 16 1148 1154 10.1158/1055-9965.EPI-07-0085 17548677 (Pubitemid 46984951)
    • (2007) Cancer Epidemiology Biomarkers and Prevention , vol.16 , Issue.6 , pp. 1148-1154
    • McCormack, V.A.1    Highnam, R.2    Perry, N.3    Silva, I.D.S.4
  • 2
    • 43149112727 scopus 로고    scopus 로고
    • Mammographic density. Potential mechanisms of breast cancer risk associated with mammographic density: Hypotheses based on epidemiological evidence
    • 10.1186/bcr1831 18226174
    • LJ Martin NF Boyd 2008 Mammographic density. Potential mechanisms of breast cancer risk associated with mammographic density: hypotheses based on epidemiological evidence Breast Cancer Res 10 201 10.1186/bcr1831 18226174
    • (2008) Breast Cancer Res , vol.10 , pp. 201
    • Martin, L.J.1    Boyd, N.F.2
  • 3
    • 27544485736 scopus 로고    scopus 로고
    • The association of endogenous sex steroids and sex steroid binding proteins with mammographic density: Results from the postmenopausal estrogen/progestin interventions mammographic density study
    • DOI 10.1093/aje/kwi286
    • GA Greendale SL Palla G Ursin GA Laughlin C Crandall MC Pike BA Reboussin 2005 The association of endogenous sex steroids and sex steroid binding proteins with mammographic density: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density Study Am J Epidemiol 162 826 834 10.1093/aje/kwi286 16177147 (Pubitemid 41541366)
    • (2005) American Journal of Epidemiology , vol.162 , Issue.9 , pp. 826-834
    • Greendale, G.A.1    Palla, S.L.2    Ursin, G.3    Laughlin, G.A.4    Crandall, C.5    Pike, M.C.6    Reboussin, B.A.7
  • 4
  • 6
    • 34547787600 scopus 로고    scopus 로고
    • Endogenous hormone levels, mammographic density, and subsequent risk of breast cancer in postmenopausal women
    • DOI 10.1093/jnci/djm062
    • RM Tamimi C Byrne GA Colditz SE Hankinson 2007 Endogenous hormone levels, mammographic density, and subsequent risk of breast cancer in postmenopausal women J Natl Cancer Inst 99 1178 1187 1:CAS:528:DC%2BD2sXpt1aktr8%3D 10.1093/jnci/djm062 17652278 (Pubitemid 47233068)
    • (2007) Journal of the National Cancer Institute , vol.99 , Issue.15 , pp. 1178-1187
    • Tamimi, R.M.1    Byrne, C.2    Colditz, G.A.3    Hankinson, S.E.4
  • 7
    • 0023519279 scopus 로고
    • The importance of local synthesis of estrogen within the breast
    • 1:STN:280:DyaL1M%2Fntlaitw%3D%3D 10.1016/0039-128X(87)90037-7 3504615
    • WR Miller J O'Neill 1987 The importance of local synthesis of estrogen within the breast Steroids 50 537 548 1:STN:280:DyaL1M%2Fntlaitw%3D%3D 10.1016/0039-128X(87)90037-7 3504615
    • (1987) Steroids , vol.50 , pp. 537-548
    • Miller, W.R.1    O'Neill, J.2
  • 8
    • 84978805009 scopus 로고    scopus 로고
    • Expression of estrogen responsive genes in breast cancers correlates with plasma estradiol levels in postmenopausal women
    • Neoadjuvant Letrozole Study Group
    • AK Dunbier H Anderson E Folkerd Z Ghazoui IE Smith MJ Ellis M Dowsett Neoadjuvant Letrozole Study Group 2009 Expression of estrogen responsive genes in breast cancers correlates with plasma estradiol levels in postmenopausal women Cancer Res 69 63
    • (2009) Cancer Res , vol.69 , pp. 63
    • Dunbier, A.K.1    Anderson, H.2    Folkerd, E.3    Ghazoui, Z.4    Smith, I.E.5    Ellis, M.J.6    Dowsett, M.7
  • 9
    • 0345314101 scopus 로고    scopus 로고
    • Pathological features of breast cancer response following neoadjuvant treatment with either letrozole or tamoxifen
    • DOI 10.1016/S0959-8049(02)00600-7, PII S0959804902006007
    • WR Miller JM Dixon L Macfarlane D Cameron TJ Anderson 2003 Pathological features of breast cancer response following neoadjuvant treatment with either letrozole or tamoxifen Eur J Cancer 39 462 468 1:CAS:528:DC%2BD3sXhtVemurY%3D 10.1016/S0959-8049(02)00600-7 12751376 (Pubitemid 36173690)
    • (2003) European Journal of Cancer , vol.39 , Issue.4 , pp. 462-468
    • Miller, W.R.1    Dixon, J.M.2    Macfarlane, L.3    Cameron, D.4    Anderson, T.J.5
  • 10
    • 0032031754 scopus 로고    scopus 로고
    • In situ aromatization enhances breast tumor estradiol levels and cellular proliferation
    • 1:CAS:528:DyaK1cXhsFersrk%3D 9500452
    • W Yue JP Wang CJ Hamilton LM Demers RJ Santen 1998 In situ aromatization enhances breast tumor estradiol levels and cellular proliferation Cancer Res 58 927 932 1:CAS:528:DyaK1cXhsFersrk%3D 9500452
    • (1998) Cancer Res , vol.58 , pp. 927-932
    • Yue, W.1    Wang, J.P.2    Hamilton, C.J.3    Demers, L.M.4    Santen, R.J.5
  • 11
    • 0025248092 scopus 로고
    • A phase i trial of CGS 16949A. A new aromatase inhibitor
    • 1:STN:280 :DyaK3c7mslGrtw%3D% 3D 10.1002/1097-0142(199 00315)65:6<12 79::AID-CNCR282 0650604>3.0.CO;2-3 2137721
    • A Lipton HA Harvey LM Demers JR Hanagan MT Mulagha GM Kochak S Fitzsimmons SI Sanders RJ Santen 1990 A phase I trial of CGS 16949A. A new aromatase inhibitor Cancer 65 1279 1285 1:STN:280:DyaK3c7mslGrtw%3D%3D 10.1002/1097-0142(19900315)65:6<1279::AID-CNCR2820650604>3.0.CO;2-3 2137721
    • (1990) Cancer , vol.65 , pp. 1279-1285
    • Lipton, A.1    Harvey, H.A.2    Demers, L.M.3    Hanagan, J.R.4    Mulagha, M.T.5    Kochak, G.M.6    Fitzsimmons, S.7    Sanders, S.I.8    Santen, R.J.9
  • 12
    • 0032977449 scopus 로고    scopus 로고
    • Aromatase and its inhibitors
    • DOI 10.1016/S0960-0760(99)00051-5, PII S0960076099000515
    • A Brodie Q Lu B Long 1999 Aromatase and its inhibitors J Steroid Biochem Mol Biol 69 205 210 1:CAS:528:DyaK1MXktlOmtLY%3D 10.1016/S0960-0760(99)00051-5 10418994 (Pubitemid 29305538)
    • (1999) Journal of Steroid Biochemistry and Molecular Biology , vol.69 , Issue.1-6 , pp. 205-210
    • Brodie, A.1    Lu, Q.2    Long, B.3
  • 13
    • 27644458191 scopus 로고    scopus 로고
    • Choosing between an aromatase inhibitor and tamoxifen in the adjuvant setting
    • DOI 10.1097/01.cco.0000180434.31991.bf
    • L Morales P Neven R Paridaens 2005 Choosing between an aromatase inhibitor and tamoxifen in the adjuvant setting Curr Opin Oncol 17 559 565 1:CAS:528:DC%2BD2MXhtFSis7%2FO 10.1097/01.cco.0000180434.31991.bf 16224233 (Pubitemid 41566408)
    • (2005) Current Opinion in Oncology , vol.17 , Issue.6 , pp. 559-565
    • Morales, L.1    Neven, P.2    Paridaens, R.3
  • 15
    • 33845883534 scopus 로고    scopus 로고
    • Mammographic density: A harmonally responsive risk factor for breast cancer
    • DOI 10.1258/136218006779160436
    • NF Boyd LJ Martin MJ Yaffe S Minkin 2006 Mammographic density: a hormonally responsive risk factor for breast cancer J Br Menopause Soc 12 186 193 10.1258/136218006779160436 17178021 (Pubitemid 46017608)
    • (2006) Journal of the British Menopause Society , vol.12 , Issue.4 , pp. 186-193
    • Boyd, N.F.1    Martin, L.J.2    Yaffe, M.J.3    Minkin, S.4
  • 16
    • 0041654020 scopus 로고    scopus 로고
    • Mammographic density is related to stroma and stromal proteoglycan expression
    • 1:CAS:528:DC%2BD3sXntFaksb4%3D 10.1186/bcr622 12927043
    • S Alowami S Troup S Al-Haddad I Kirkpatrick PH Watson 2003 Mammographic density is related to stroma and stromal proteoglycan expression Breast Cancer Res 5 R129 R135 1:CAS:528:DC%2BD3sXntFaksb4%3D 10.1186/bcr622 12927043
    • (2003) Breast Cancer Res , vol.5
    • Alowami, S.1    Troup, S.2    Al-Haddad, S.3    Kirkpatrick, I.4    Watson, P.H.5
  • 18
    • 33746497527 scopus 로고    scopus 로고
    • Dense breast stromal tissue shows greatly increased concentration of breast epithelium but no increase in its proliferative activity
    • DOI 10.1186/bcr1408
    • D Hawes S Downey CL Pearce S Bartow P Wan MC Pike AH Wu 2006 Dense breast stromal tissue shows greatly increased concentration of breast epithelium but no increase in its proliferative activity Breast Cancer Res 8 R24 10.1186/bcr1408 16646977 (Pubitemid 44377907)
    • (2006) Breast Cancer Research , vol.8 , Issue.2
    • Hawes, D.1    Downey, S.2    Pearce, C.L.3    Bartow, S.4    Wan, P.5    Pike, M.C.6    Wu, A.H.7
  • 19
    • 0030033855 scopus 로고    scopus 로고
    • Cellular proliferative activity of mammographic normal dense and fatty tissue determined by DNA S phase percentage
    • DOI 10.1007/BF01806504
    • PC Stomper RB Penetrante SB Edge MA Arredondo LE Blumenson CC Stewart 1996 Cellular proliferative activity of mammographic normal dense and fatty tissue determined by DNA S phase percentage Breast Cancer Res Treat 37 229 236 1:STN:280:DyaK28vit1GitQ%3D%3D 10.1007/BF01806504 8825134 (Pubitemid 26030100)
    • (1996) Breast Cancer Research and Treatment , vol.37 , Issue.3 , pp. 229-236
    • Stomper, P.C.1    Penetrante, R.B.2    Edge, S.B.3    Arredondo, M.A.4    Blumenson, L.E.5    Stewart, C.C.6
  • 20
    • 34548570831 scopus 로고    scopus 로고
    • Mammographic density does not correlate with Ki-67 expression or cytomorphology in benign breast cells obtained by random periareolar fine needle aspiration from women at high risk for breast cancer
    • DOI 10.1186/bcr1683
    • QJ Khan BF Kimler AP O'Dea CM Zalles P Sharma CJ Fabian 2007 Mammographic density does not correlate with Ki-67 expression or cytomorphology in benign breast cells obtained by random periareolar fine needle aspiration from women at high risk for breast cancer Breast Cancer Res 9 R35 10.1186/bcr1683 17537236 (Pubitemid 350215172)
    • (2007) Breast Cancer Research , vol.9 , Issue.3
    • Khan, Q.J.1    Kimler, B.F.2    O'Dea, A.P.3    Zalles, C.M.4    Sharma, P.5    Fabian, C.J.6
  • 22
    • 38049055303 scopus 로고    scopus 로고
    • Histologic changes in the breast with menopausal hormone therapy use: Correlation with breast density, estrogen receptor, progesterone receptor, and proliferation indices
    • 17558338
    • JA Harvey RJ Santen GR Petroni VE Bovbjerg ME Smolkin FS Sheriff J Russo 2008 Histologic changes in the breast with menopausal hormone therapy use: correlation with breast density, estrogen receptor, progesterone receptor, and proliferation indices Menopause 15 67 73 17558338
    • (2008) Menopause , vol.15 , pp. 67-73
    • Harvey, J.A.1    Santen, R.J.2    Petroni, G.R.3    Bovbjerg, V.E.4    Smolkin, M.E.5    Sheriff, F.S.6    Russo, J.7
  • 23
    • 0031027033 scopus 로고    scopus 로고
    • Aromatase activity and expression in breast cancer and benign breast tissue stromal cells
    • DOI 10.1210/jc.82.1.200
    • SJ Santner RJ Pauley L Tait J Kaseta RJ Santen 1997 Aromatase activity and expression in breast cancer and benign breast tissue stromal cells J Clin Endocrinol Metab 82 200 208 1:CAS:528:DyaK2sXkt1egsA%3D%3D 10.1210/jc.82.1.200 8989259 (Pubitemid 27021297)
    • (1997) Journal of Clinical Endocrinology and Metabolism , vol.82 , Issue.1 , pp. 200-208
    • Santner, S.J.1    Pauley, R.J.2    Tait, L.3    Kaseta, J.4    Santen, R.J.5
  • 24
    • 66649111397 scopus 로고    scopus 로고
    • IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells
    • 1:CAS:528:DC%2BD1MXlsFCgtr0%3D 10.1210/me.2008-0468 19221050
    • S Ghosh A Choudary S Ghosh N Musi Y Hu R Li 2009 IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells Mol Endocrinol 23 662 670 1:CAS:528:DC%2BD1MXlsFCgtr0%3D 10.1210/me.2008-0468 19221050
    • (2009) Mol Endocrinol , vol.23 , pp. 662-670
    • Ghosh, S.1    Choudary, A.2    Ghosh, S.3    Musi, N.4    Hu, Y.5    Li, R.6
  • 26
    • 0035266249 scopus 로고    scopus 로고
    • Malignant breast epithelial cells stimulate aromatase expression via promoter II in human adipose fibroblasts: An epithelial-stromal interaction in breast tumors mediated by CCAAT/enhancer binding protein beta
    • 1:CAS:528:DC%2BD3MXit1OgtL8%3D 11280806
    • J Zhou B Gurates S Yang S Sebastian SE Bulun 2001 Malignant breast epithelial cells stimulate aromatase expression via promoter II in human adipose fibroblasts: an epithelial-stromal interaction in breast tumors mediated by CCAAT/enhancer binding protein beta Cancer Res 61 2328 2334 1:CAS:528: DC%2BD3MXit1OgtL8%3D 11280806
    • (2001) Cancer Res , vol.61 , pp. 2328-2334
    • Zhou, J.1    Gurates, B.2    Yang, S.3    Sebastian, S.4    Bulun, S.E.5
  • 27
    • 0027131199 scopus 로고
    • A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription
    • DOI 10.1210/jc.77.6.1622
    • SE Bulun TM Price J Aitken MS Mahendroo ER Simpson 1993 A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription J Clin Endocrinol Metab 77 1622 1628 1:CAS:528:DyaK2cXhtVenu7c%3D 10.1210/jc.77.6.1622 8117355 (Pubitemid 24000924)
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.77 , Issue.6 , pp. 1622-1628
    • Bulun, S.E.1    Price, T.M.2    Aitken, J.3    Mahendroo, M.S.4    Simpson, E.R.5
  • 28
    • 0028076949 scopus 로고
    • Regulation of aromatase expression in human tissues
    • DOI 10.1007/BF00682738
    • SE Bulun ER Simpson 1994 Regulation of aromatase expression in human tissues Breast Cancer Res Treat 30 19 29 1:CAS:528:DyaK2cXmt1ais7w%3D 10.1007/BF00682738 7949202 (Pubitemid 24250756)
    • (1994) Breast Cancer Research and Treatment , vol.30 , Issue.1 , pp. 19-29
    • Bulun, S.E.1    Simpson, E.R.2
  • 29
    • 0029918463 scopus 로고    scopus 로고
    • Distribution of aromatase p450 transcripts and adipose fibroblasts in the human breast
    • DOI 10.1210/jc.81.3.1273
    • SE Bulun G Sharda J Rink S Sharma ER Simpson 1996 Distribution of aromatase P450 transcripts and adipose fibroblasts in the human breast J Clin Endocrinol Metab 81 1273 1277 1:CAS:528:DyaK28Xhs1agtL0%3D 10.1210/jc.81.3.1273 8772611 (Pubitemid 26084463)
    • (1996) Journal of Clinical Endocrinology and Metabolism , vol.81 , Issue.3 , pp. 1273-1277
    • Bulun, S.E.1    Sharda, G.2    Rink, J.3    Sharma, S.4    Simpson, E.R.5
  • 30
    • 48149088637 scopus 로고    scopus 로고
    • Development of a high sensitivity, nested Q-PCR assay for mouse and human aromatase
    • 1:CAS:528:DC%2BD1cXptVCntLs%3D 10.1007/s10549-007-9792-4 17975728
    • GJ Liu YS Wu D Brenin W Yue S Aiyar A Gompel JP Wang RR Tekmal RJ Santen 2008 Development of a high sensitivity, nested Q-PCR assay for mouse and human aromatase Breast Cancer Res Treat 111 343 351 1:CAS:528:DC%2BD1cXptVCntLs%3D 10.1007/s10549-007-9792-4 17975728
    • (2008) Breast Cancer Res Treat , vol.111 , pp. 343-351
    • Liu, G.J.1    Wu, Y.S.2    Brenin, D.3    Yue, W.4    Aiyar, S.5    Gompel, A.6    Wang, J.P.7    Tekmal, R.R.8    Santen, R.J.9
  • 31
    • 0021149871 scopus 로고
    • In situ estrogen production via the estrone sulfatase pathway in breast tumors: Relative importance versus the aromatase pathway
    • 1:CAS:528:DyaL2cXks1Khtrk%3D 10.1210/jcem-59-1-29 6725522
    • SJ Santner PD Feil RJ Santen 1984 In situ estrogen production via the estrone sulfatase pathway in breast tumors: relative importance versus the aromatase pathway J Clin Endocrinol Metab 59 29 33 1:CAS:528:DyaL2cXks1Khtrk%3D 10.1210/jcem-59-1-29 6725522
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 29-33
    • Santner, S.J.1    Feil, P.D.2    Santen, R.J.3
  • 34
    • 33947689213 scopus 로고    scopus 로고
    • Pilot study of the impact of letrozole vs. placebo on breast density in women completing 5 years of tamoxifen
    • DOI 10.1016/j.breast.2006.10.007, PII S0960977606001937
    • CM Vachon JN Ingle VJ Suman CG Scott H Gottardt JE Olson PE Goss 2007 Pilot study of the impact of letrozole vs. placebo on breast density in women completing 5 years of tamoxifen Breast 16 204 210 1:STN:280: DC%2BD2s7pvFSgtg%3D%3D 10.1016/j.breast.2006.10.007 17145182 (Pubitemid 46499237)
    • (2007) Breast , vol.16 , Issue.2 , pp. 204-210
    • Vachon, C.M.1    Ingle, J.N.2    Suman, V.J.3    Scott, C.G.4    Gottardt, H.5    Olson, J.E.6    Goss, P.E.7
  • 35
    • 2342571082 scopus 로고    scopus 로고
    • Tamoxifen and breast density in women at increased risk of breast cancer
    • 1:CAS:528:DC%2BD2cXjsVektb4%3D 10.1093/jnci/djh106 15100340
    • J Cuzick J Warwick E Pinney RM Warren SW Duffy 2004 Tamoxifen and breast density in women at increased risk of breast cancer J Natl Cancer Inst 96 621 628 1:CAS:528:DC%2BD2cXjsVektb4%3D 10.1093/jnci/djh106 15100340
    • (2004) J Natl Cancer Inst , vol.96 , pp. 621-628
    • Cuzick, J.1    Warwick, J.2    Pinney, E.3    Warren, R.M.4    Duffy, S.W.5
  • 36
    • 78651090566 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial (NCIC CTG MAP1) examining the effects of letrozole on mammographic breast density and other end organs in postmenopausal women
    • 2009 Dec 6 [Epub ahead of print]
    • Cigler T, Tu D, Yaffe MJ, Findlay B, Verma S, Johnston D, Richardson H, Hu H, Qi S, Goss PE (2009) A randomized, placebo-controlled trial (NCIC CTG MAP1) examining the effects of letrozole on mammographic breast density and other end organs in postmenopausal women. Breast Cancer Res Treat. 2009 Dec 6 [Epub ahead of print]
    • (2009) Breast Cancer Res Treat
    • Cigler, T.1    Tu, D.2    Yaffe, M.J.3    Findlay, B.4    Verma, S.5    Johnston, D.6    Richardson, H.7    Hu, H.8    Qi, S.9    Goss, P.E.10
  • 38
    • 58249085105 scopus 로고    scopus 로고
    • Aromatase inhibitors and mammographic breast density in postmenopausal women receiving hormone therapy
    • 10.1097/gme.0b013e31816956c3 18480735
    • NA Mousa P Crystal WL Wolfman MA Bedaiwy RF Casper 2008 Aromatase inhibitors and mammographic breast density in postmenopausal women receiving hormone therapy Menopause 15 875 884 10.1097/gme.0b013e31816956c3 18480735
    • (2008) Menopause , vol.15 , pp. 875-884
    • Mousa, N.A.1    Crystal, P.2    Wolfman, W.L.3    Bedaiwy, M.A.4    Casper, R.F.5


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