Genetic and functional heterogeneity of the hepatitis C virus p7 ion channel during natural chronic infection

Virology

Volumn 423, Issue 1, 2012, Pages 30-37

  Li, Hui ^a   Atkins, Elizabeth ^b   Bruckner, Joseph ^a   McArdle, Susan ^a   Qiu, Wan Chong ^a   Thomassen, Lisa V ^a   Scott, John ^a   Shuhart, Margaret C ^a   Livingston, Stephen ^c   Townshend Bulson, Lisa ^c   McMahon, Brian J ^c   Harris, Mark ^b   Griffin, Stephen ^b,d   Gretch, David R ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c ALASKA NATIVE TRIBAL HEALTH CONSORTIUM   (United States)

^d UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Functional heterogeneity; Genetic heterogeneity; Hepatitis C virus; Hyperactive channel activity; P7 ion channel; PH activated channel activity

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; FLUORESCENT DYE; ION CHANNEL; LIPOSOME; PROTEIN VP7;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CHANNEL GATING; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; DISEASE SEVERITY; FEMALE; GENETIC HETEROGENEITY; GENETIC VARIABILITY; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; LIVER FIBROSIS; MALE; MIXED INFECTION; MOLECULAR CLONING; PH; PRIORITY JOURNAL; PROTEIN ASSEMBLY; SEQUENCE ALIGNMENT; VIRUS GENOME; VIRUS ISOLATION; VIRUS RELEASE;

ADULT; AMINO ACID SEQUENCE; FEMALE; GENETIC VARIATION; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; VIRAL PROTEINS;

HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 84855347059     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2011.11.011     Document Type: Article

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