A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondria

Journal of General Virology

Volumn 85, Issue 2, 2004, Pages 451-461

  Griffin, Stephen D C ^a   Harvey, Ruth ^c,d   Clarke, Dean S ^a   Barclay, Wendy S ^b   Harris, Mark ^a   Rowlands, David J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b UNIVERSITY OF READING   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d CENTRAL PUBLIC HEALTH LABORATORY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMANTADINE; ANTIVIRUS AGENT; HELIX LOOP HELIX PROTEIN; ION CHANNEL; MEMBRANE PROTEIN; PROTEIN P7; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; BOVINE DIARRHEA VIRUS; CELL ASSAY; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; DRUG SENSITIVITY; DRUG TARGETING; ENZYME ACTIVITY; GENETIC CONSERVATION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; INFLUENZA VIRUS; INTRACELLULAR MEMBRANE; MAMMAL CELL; MITOCHONDRIAL MEMBRANE; MUTATION; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

AMANTADINE; AMINO ACID SEQUENCE; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; HEPACIVIRUS; HUMANS; ION CHANNELS; MAMMALS; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT; VIRAL MATRIX PROTEINS; VIRAL PROTEINS;

BOVINAE; HEPATITIS C VIRUS; INFLUENZA VIRUS; MAMMALIA;

EID: 1342289027     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.19634-0     Document Type: Article

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