MYST protein acetyltransferase activity requires active site lysine autoacetylation

EMBO Journal

Volumn 31, Issue 1, 2012, Pages 58-70

  Yuan, Hua ^a   Rossetto, Dorine ^b   Mellert, Hestia ^c   Dang, Weiwei ^a   Srinivasan, Madhusudan ^d   Johnson, Jamel ^a   Hodawadekar, Santosh ^a   Ding, Emily C ^a   Speicher, Kaye ^a   Abshiru, Nebiyu ^e   Perry, Rocco ^a   Wu, Jiang ^f   Yang, Chao ^f   Zheng, Y George ^f   Speicher, David W ^a   Thibault, Pierre ^e   Verreault, Alain ^g   Johnson, F Bradley ^a   Berger, Shelley L ^a   Sternglanz, Rolf ^d   McMahon, Steven B ^c   Côté, Jacques ^b   Marmorstein, Ronen ^a   more..

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b LAVAL UNIVERSITY   (Canada)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d STONY BROOK UNIVERSITY   (United States)

^e UNIVERSITÉ DE MONTRÉAL   (Canada)

^f GEORGIA STATE UNIVERSITY   (United States)

^g INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

acetylation; HATs; MYST proteins

Indexed keywords

ACYLTRANSFERASE; ENZYME INHIBITOR; ESA1 PROTEIN; FUNGAL PROTEIN; GLUTAMIC ACID; LYSINE; MOF PROTEIN; MYST PROTEIN LYSINE ACETYLTRANSFERASE; RECOMBINANT PROTEIN; SAS2 PROTEIN; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; AUTOACETYLATION; BIOCHEMISTRY; CATALYSIS; CELL FUNCTION; CELL VIABILITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN PROCESSING; PROTEIN STRUCTURE; YEAST CELL;

ACETYLATION; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HISTONE ACETYLTRANSFERASES; HISTONES; HUMANS; LYSINE; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA;

EID: 84855341934     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.382     Document Type: Article

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