Chronic blockade of cannabinoid CB 2 receptors induces anxiolytic-like actions associated with alterations in GABA A receptors

British Journal of Pharmacology

Volumn 165, Issue 4, 2012, Pages 951-964

  García Gutiérrez, María S ^a,b   García Bueno, Borja ^c   Zoppi, Silvia ^c   Leza, Juan C ^c   Manzanares, Jorge ^a,b  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

AM630; anxiety disorders; CB 2 receptor; DB A2 mice; GABA A 2; GABA A 2; JWH133

Indexed keywords

1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; CANNABINOID 2 RECEPTOR;

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2 GENE; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2 GENE; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANQUILIZING ACTIVITY; TREATMENT DURATION; TREATMENT RESPONSE; WESTERN BLOTTING;

AMYGDALA; ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; BEHAVIOR, ANIMAL; CANNABINOIDS; CEREBRAL CORTEX; GENE EXPRESSION; INDOLES; MALE; MICE; MICE, INBRED DBA; MICE, INBRED ICR; RECEPTOR, CANNABINOID, CB2; RECEPTORS, GABA-A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84855340630     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01625.x     Document Type: Article

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