Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4

PLoS Pathogens

Volumn 7, Issue 12, 2011, Pages

  McFadden, Nora ^a   Bailey, Dalan ^a   Carrara, Guia ^a,c   Benson, Alicia ^b   Chaudhry, Yasmin ^a   Shortland, Amita ^c   Heeney, Jonathan ^c   Yarovinsky, Felix ^b   Simmonds, Peter ^d   Macdonald, Andrew ^e   Goodfellow, Ian ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CASPASE 3; CASPASE 7; CELL PROTEIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GENOMIC RNA; ISG54 PROTEIN; LEUCINE; MDA5 PROTEIN; MESSENGER RNA; METHIONINE; MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN; MUTANT PROTEIN; PROTEIN VP1; PROTEIN VP2; RETINOIC ACID INDUCIBLE PROTEIN I; STAT1 PROTEIN; SUBGENOMIC RNA; TBK1 PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR; VIRULENCE FACTOR 1; VIRUS RNA; VIRUS PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALICIVIRUS INFECTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; INNATE IMMUNITY; INTESTINE VILLUS; LIVER; MITOCHONDRION; MOUSE; NONHUMAN; NOROVIRUS; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; OPEN READING FRAME 4; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SPLEEN; STOP CODON; VIRUS CULTURE; VIRUS LOAD; VIRUS REPLICATION; VIRUS STRAIN; WILD TYPE; ANIMAL; C57BL MOUSE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; IMMUNOPRECIPITATION; METABOLISM; MOLECULAR GENETICS; MOUSE MUTANT; PATHOGENICITY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE GENETICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRULENCE; WESTERN BLOTTING;

CALICIVIRIDAE; MURINE NOROVIRUS; MUS; NOROVIRUS; RNA VIRUSES;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CALICIVIRIDAE INFECTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; IMMUNITY, INNATE; IMMUNOPRECIPITATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; NOROVIRUS; OPEN READING FRAMES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE GENETICS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; VIRAL PROTEINS; VIRULENCE; VIRULENCE FACTORS; VIRUS REPLICATION;

EID: 84855269254     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002413     Document Type: Article

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