V and C proteins of measles virus function as virulence factors in vivo

Virology

Volumn 267, Issue 1, 2000, Pages 80-89

  Patterson, John B ^a   Thomas, Diane ^a   Lewicki, Hanna ^a   Billeter, Martin A ^b   Oldstone, Michael B A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

VIRULENCE FACTOR; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; MEASLES VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS EXPRESSION; VIRUS LOAD; VIRUS REPLICATION; VIRUS VIRULENCE;

ANIMALIA; DNA VIRUSES; MEASLES VIRUS; MUS MUSCULUS; RNA VIRUSES;

EID: 0034141209     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1999.0118     Document Type: Article

References (37)

1. Bellini W.J., Englund G., Rozenblatt S., Arnheiter H., Richardson C.D. Measles virus P gene codes for two proteins. J. Virol. 1985;908-919.
2. Cadd T., Garcin D., Tapparel C., Itoh M., Homma M., Roux L., Curran J., Kolakofsky D. the Sendai paramyxovirus acccessory C proteins inhibit viral genome amplification in a promoter-specific fashion. J. Virol. 70:1996;5067-5074.
3. Campbell I., Stalder A., Akwa Y., Pagenstecher A., Asensio V. Transgenic models to study the actions of cytokines in the central nervous system. Neuroimmunomodulation. 5:1998;126-135.
4. Cattaneo R., Kaelin K., Baczko K., Billeter M. A. Measles virus editing provides an additional cysteine-rich protein. Cell. 56:1988;759-764.
5. Chen Z., Li Y., Krug R. M. Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3′-end processing machinery. EMBO J. 18:1999;2273-2283.
6. Curran J., Boeck R., Kolakofsky D. The sendai virus P gene expresses both an essential protein and an inhibitor of RNA synthesis. EMBO J. 10:1991;3079-3085.
7. Delenda C., Taylor G., Hausmann S., Garcin D., Kolakofsky D. Sendai viruses with altered P, V, and W protein expression. Virology. 242:1998;327-337.
8. Didcock L., Young D. F., Goodbourn S., Randall R. E. Sendai virus and simian virus 5 block activation of interferon-responsive genes: Importance for virus pathogenesis. J. Virol. 73:1999;3125-3133.
9. Escoffier C., Manie S., Vincent S., Muller C. P., Billeter M., Gerlier D. Nonstructural C protein is required for efficient measles virus replication in human peripheral blood cells. J. Virol. 73:1999;1695-1698.
10. Garcia-Sastre A., Egorov A., Matassov D., Brandt S., Levy D. E., Durbin J. E., Palese P., Mustert T. Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems. Virology. 252:1998;324-330.
11. Garcin D., Latorve P., Kolakofsky D. Sendai virus C proteins counteract the interon-mediated induction of an antiviral state. J. Virol. 73:1999;6559-6565.
12. Griffin D. E., Bellini W. J. Measles virus. Fields B. N., Knipe D. M., Howley P. M. Virology. 1996;1267-1312 Lippincott-Raven, Philadelphia.
13. Horikami S. M., Smallwood S., Moyer S. A. The Sendai virus V protein interacts with the NP protein to regulated viral genome RNA replication. Virology. 222:1996;383-390.
14. Joly E., Mucke L., Oldstone M. A. B. Viral persistence in neurons explained by lack of major histocompatibility class I expression expression. Science. 253:1991;1283-1285.
15. Kato A., Katsuhiro K., Sakai Y., Yoshida T., Shioda T., Nagai Y. Importance of the cysteine-rich carboxy-terminal half of V protein for sendai virus pathogenisis. J. Virol. 71:1997a;7266-7272.
16. Kato A., Kiyotani K., Sakai Y., Yoshida T., Nagai Y. The paramyxovirus, Sendai virus, V protein encodes a luxury function required for viral pathogenisis. EMBO J. 16:1997b;578-587.
17. Kurotani A., Kiyotani K., Kato A., Shioda T., Sakai Y., Mizumoto K., Yoshida T., Nagai Y. Sendai virus C proteins are categorically nonessential gene products but silencing their expression severly impairs viral replication and pathogenesis. Genes to Cells. 3:1998;111-124.
18. Lamb R. A., Kolakofsky D. Paramyxoviridea: The viruses and their replication. Fields B. N., Knipe D. M., Howley P. M. Virology. 1996;1177-1204 Lippincott-Raven, New York.
19. Lawrence D. M., Vaughn M. M., Belman A. R., Cole J. S., Rall G. F. Immune response-mediated protection of aldult but not neonatal mice from neuron-restricted measles virus infection and central nervous system disease. J. Virol. 73:1999;1795-1801.
20. Lin G. Y., Paterson R. G., Richardson C. D., Lamb R. A. The V protein of the paramyxovirus SV5 interacts with damage-specific DNA binding protein. Virology. 249:1998;189-200.
21. Liston P., Briedis D. J. Measles virus V protein binds zinc. Virology. 198:1994;399-404.
22. Manchester M., Eto D. S., Oldstone M. B. A. Characterization of the inflammatory response during acute measles encephalitis in NSE-CD46 transgenic mice. J. Neuroimmunol. 2:1999;207-217.
23. Marion R. A., Fortes P., Beloso A., Dotti C., Ortin J. A human sequence homologue of staufen is an RNA-binding protein that is associated with polysomes and localizes to the rough endoplasmic reticulum. Mol. Cell. Biol. 19:1999;2212-2219.
24. Oldstone M. B. A., Lewicki H., Thomas D., Tishon A., Dales S., Patterson J., Manchester M., Homann D., Naniche D., Holz A. Measles virus infection in a transgenic model: Virus-induced immunosupression and central nervous system disease. Cell. 98:1999;629-640.
25. Ortin J. Multiple levels of post-transcriptional regulation of influenza virus gene expression. Semin. Virol. 3:1998;335-342.
26. Paterson R. G., Leser G. P., Shaughnessy M. A., Lamb R. A. The paramyxovirus SV5 V protein binds two atoms of zinc. Virology. 198:1995;399-404.
27. Portner A., Gupta K. C., Seyer J. M., Beachy E. H., Kingsbury D. W. Localization and characterization of sedai viurs nonstrucural C and C′ proteins by antibodies against synthetic peptides. Virus Res. 6:1986;109-121.
28. Radecke F., Billeter M. A. The nonstructural C protein is not essential for multiplication of edmonston B strain measles virus in cultured cells. Virology. 217:1996;418-421.
29. Radecke F., Spielhofer P., Schnieder H., Kaelin K., Huber M., Dotsch C., Christiansen G., Billeter M. A. Rescue of measles virus from cloned DNA. EMBO J. 14:1995;5773-5784.
30. Rall G. F., Manchester M., Daniels L. R., Callahan E., Belman A., Oldstone M. B. A. A transgenic mouse model for measles virus infection of the brain. Proc. Natl. Acad. Sci. USA. 94:1997;2243-2248.
31. Schneider H., Kaelin K., Billeter M. A. Recombinant measles viruses defective for RNA editing and V protein synthesis are viable in cultured cells. Virology. 277:1997;314-322.
32. Tan S. L., Katz M. G. Biochmemical and genetic evidence for complex formation between the influenza A virus NS1 protein and the interferon-induced PKR protein kinase. J. Int. Cytol. Res. 18:1998;757-766.
33. Tapparel C., Hausmann S., Pelet S., Curran J., Kolakofsky D., Roux L. Inhibition of sendai virus genome replication due to promoter-increased selectivity: A possible role of the accessory proteins. J. Virol. 71:1997;9588-9599.
34. Tober C., Seufert M., Schneider H., Billeter M. A., Johnston I. C. D., Niewiesk S., ter Meulen V., Schneider-Schaules S. Expression of measles virus V protein is associated with pathogenicity and control of viral RNA synthesis. J. Virol. 72:1998;8124-8132.
35. Valsamakis A., Schneider H., Auwaerter P. G., Kaneshima H., Billeter M. A., Griffin D. E. Recombinant measles viruses with mutations in the C, V, or F gene have altered growth phenotypes in vivo. J. Virol. 72:1998;7754-7761.
36. Wang W., Riedel K., Lynch P., Chien C. Y., Montelione G. T., Krug R. M. RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific amino acids. RNA. 5:1999;2212-2219.
37. Wardrop E. A., Briedis D. J. Characterization of V protein in measles virus-infected cells. J. Virol. 65:1991;3421-3428.